Background and purpose: Gin Ga Chu Yo(該家樞要) was written in the year 1359 by Hwal Su(滑壽) who was a famous oriental doctor between Won(元) and Myeong(明) dynasty. As specialized in sphygmology(脈學), this book was brought together most things about sphygmology(脈學) before Won(元) dynasty by the author. Moreover he added the self-realized things to this book. Methods: In this book, there are all 20 chapters; Chu Yo Hyeon Eon(樞要玄言), Jwa U Su Bae Jang Bu Bu Wi (左右手配臟腑部立), O Jang(五臟), Sa Si peong Maek(四時平脈), Nae Gyeong Sam Bu Maek Beop(內經三部脈法), Ho Heup Chim Bu Jeong O Jang Beop(呼吸沈浮定五臟法), In Ji Ha Gyeong Jung I Jeong O Jang Beop(因指下輕重以定五臟法), Sam Bu So Ju(三部所主), Ji Maek Su Beop(持脈手法), Maek Gwi Yu Sin(脈實有神), Maek Eum Yang Yu Seong(脈陰陽類成 ), Gyeom Hyeon Maek Ryu(兼見脈類), Je Maek Ui Gi Ryu(諸脈宜忌類), Heom Je Sa Jeung Ryu(驗諸死症類) , Sa Jeol Maek Ryu(死絶脈類), O Jang Dong Ji Maek(五藏動止脈), Bu In Maek Beop(婦人脈法), So A Maek Beop(小兒脈法), Maek Sang Tong Hoe(脈象統會), Maek Sang Ga(脈象歌) and an epilogue in the end. This treatise is made up of principal, notes, study and conclusion, we tried to make a translation faithful to the original. Results and Conclusion: Looking into this book, we can know that it is very detail in analyzing item by item, bright and simple in explaining and it is very useful in studying pulse evaluation(脈診). In his preface, Hwal Su(滑壽) expresses his opinion with firm confidence that 'Do(道) of the World scattered in several scholarships and books of method and technique(方術). Nothing of method and technique(方術 ) is more important than medicine. Nothing of medicine goes before pulse evaluation(脈診).' With such good reasons, as a student of sphygmology(脈學), I think this book is very valuable in studying pulse evaluation. So I add Hangul suffixes(吐) to a part of this book and translate it into Korean.

Background and purpose: Maek Kyoung(脈經) is a book written, compiled, and edited by Wang Hui circa 3 A.D. This book is the first technical book devoted to the diagnostics. These are very important data but never make a special study and translate. so I hope this treatise can be great help to understand diagnosis study. Methods: Maek Kyoung(脈經) consists of ten volumes, and the third volume consists of the five chapters, including inter-generation and inter-restriction of the five viscera and the six entrails and prognosis of diseases. This treatise is made up of principal, notes, study and conclusion, we tried to make a translation faithful to the original. Results and Conclusion: Chapter 3 refers to five things. The first is relation between spleen and stomach, the second is how to diagnose diseases by using intergneration and inter-restriction of five elements, the third is roles of spleen that has an influence on four viscera through four seasons, the forth is the fact that quantity of gastroqi decides prognosis of diseases, and the fifth is that climate change has influence on the seriousness of diseases. Chapter 4 refers to four things. The first is relation between lung and large intestines, the second is ordinary and extraordinary pulse condition of lung, the third is that pulse condition including its speed, and the forth is how to diagnose diseases by using intergneration and inter-restriction of five elements and climate change.

Background and purpose: The purpose of this study is to review the recent 10 year Chinese achievements on the objectification of traditional pulse diagnosis in clinical area. Methods: From the China Journal Full Text Database (中國學術期刊全文數据庫) we searched papers on pulse diagnosis by the keyword 'Maizhen'(脈診) Resulls: The researches are summarized into four parts; (1) the researches on the normal pulse in the physiological state (2) the clinical researches of pulse diagnosis on the symptom and disease diagnosis (3) the clinical researches of pulse diagnosis on the acupuncture treatment (4) the application of pulse diagnosis on the functional evaluation of the athlete. Conclusion: The undoubted principles of the traditional pulse diagnosis are evaluated by the objective clinical researches. And the researchers are trying to find a new application area over the traditional one.

Background and purpose: Cardiovascular disease will undoubtedly rise along with the aging of the 'baby-boom' generation. The purpose of this study is to find the new index of the cardiovascular aging. Methods: The effects of aging on the heart and the arterial system are surveyed in the point of structure and function. Results: Arterial stiffening is due to the fatiguing effects of periodic stress on the arterial wall and is the main reason for increasing pulse wave velocity. The systolic hypertension is caused by the early return of wave reflection. The increased after-load by the arterial change leads to the development of left ventricular hypertrophy. The reduction in left ventricular compliance cause the impairments of the diastolic function. In contrast to the lower limb, aging effect in the upper limb are almost due to the ascending aortic pressure wave and the reflected wave from the lower limb. Conclusion: We have the following points. (1) The change of physiological pulse pattern by age can be explained by the early returning of reflected wave. (2) The atrial pulse in old age are generated by the left ventricular hypertrophy.

Background and purpose: The purpose of this study is to review the recent achievements on ryodoraku and suggest new ryodoraku studies. Methods: The study papers related with ryodoraku, published in foreign countries and Korea up to the present, were collected first by internet search & journal. And then the collected papers were classified and summarized. Results and Conclusion: There are three study trends. One is finding some effect and analysis for some symptoms, another is finding a distinguishing mark and a diagnostic index, and the other is raising several points & providing solution & studying about relativity with another diagnosis. Some studies finding some effect and analysis for some symptoms are to be classified into four items(1. effect of drugs medication. 2. effect of ryodoraku therapy. 3. effect of other treatments. 4. effect of other treatments with ryodoraku therapy). Other studies finding a distinguishing mark and a diagnostic index are to be classified into two items(1. diagnostic index of symptoms. 2. distinguishing mark of disease). The other studies are to be classified into three items(1. ryodoraku introduction and raising several points at issue. 2. improvement machinery and tools. 3. studying about relativity with another diagnosis). Finally we need solving the ryodoraku problems(the condition of measurement and reproducibility, relation with Kyung-rak(經絡) and Ryodoraku, the reason of Ryodoraku points producing and etc.).

Background and and purpose : The aim of this study is to define the concept and to arrange symptoms of Blood stasis(瘀血) by review of other thesises, literatures connected with it and reserch trend, in order to making a questionnaire of Blood stasis(瘀血) Methods: By review of other thesises and literatures connected with it, we defined the concept and arranged. symptoms of Blood stasis(瘀血). Results: The concept of Blood stasis(瘀血) is summarized as stasis of blood, pollutant of blood and external blood of vessel. The causes and Symptoms of blood stasis is arranged. Conclusion: Review of literatures led to the selection of 48 items describing blood stasis pattern(瘀血證)

Background and purpose: The Han(cold)-Yol(heat) patternization is one of the most usually used diagnostic methods in oriental medicine. This is preceding studies for compensating questionnaries on Han-Yol that were made by sook-kyeng Kim. Methods: Questionnaries on Han-Yol that will be worked out should be useful for clinical examination. So We selected symptoms based on Donguibogam that is regarded as a clinical textbook in Korea. Results: It is expected that not only Sil-Yol but also Hu-Yol and Yol combined with Han can be diagnosed by new questionnaries. Conclusion: These symptoms based on Donguibogam will be made into questionnaries that can diagnose not only Sil-Yol but also Hu-Yol and Yol combined with Han.

Background: PWV is determined by dividing the distance by the time taken for the pulses traveling between two measuring sites, used as a marker of arterial stiffness and an important indicator for cardiovascular disease. Methods: A PWV measurement system, which offers a non-invasive, simple method of measurement, and simultaneous recording of six signlas(ECG, PCG and four pulse waves from carotid, femoral, radial and dorsalis pedis arteries) was developed. Seventeen healthy subjects with a mean age of 33 years(22 to 52) without any cardiovascular disease were participated for the experiment. Two observers(A and B) performed two consecutive measurements from the same subject in a random order. For the evaluation of stability and accuracy of the PWV measurement system, reproducibility of PWV from between-observer were also evaluated. Results: PWV $values(Mean{\pm}SD)$ measured by A were $7.07{\pm}1.48m/s$, $8.43{\pm}1.14m/s$ , $8.09{\pm}0.98m/s$ for aorta, arm, and leg, respectively. The values obtained from B were $6.76{\pm}1.00m/s$, $7.97{\pm}0.80m/s$, and $7.97{\pm}0.72m/s$ for aorta, arm, and leg, respectively. Between-observer $differences(mean{\pm}SEM)$ from the aorta, arm and leg were $0.14{\pm}0.15m/s$, $0.18{\pm}0.10m/s$ and $0.07{\pm}0.10m/s$. Reproducibility coefficients(2SD) from the aorta, arm, and leg were 0.62m/s, 0.84m/s and 0.86m/s. Correlation coefficients were significantly higher in aortic PWV, 0.93, compared to the coefficients for arm and leg. Coefficient of variance which reflects the reproducibility of the system ranged from $4.4{\sim}5.8%$ in all regional PWV. , Conclusion: Reproducibility of PWV in the study shows that the developed system has reliable and reproducible characteristics. The PWV measurement system used for the study offers comfortable and simple operation and provides accurate analysis and results with high reproducibility. Results of the PWV measurement system could contribute to various clinical applications in the future.

Background and purpose: We evaluated the reliability of two electrodermal measurement devices on meridian skin areas; Electro Acupuncture according to Dr. Voll (EAV) method and newly developed MIR-1. Methods: Eighteen volunteers were tested repeatedly on the same condition with each device. To explore the intra-rater, inter-rater, and test-retest reliabilities, one rater tested each subject twice in succession, then the other rater tested the subject in a row. Finally, retests on the subjects with each device were performed 1 week later. The reliability was determined by Pearson correlation and intraclass correlation statistics. Results: EAV method showed poor reliability, while MIR-1 showed good reliability. Conclusion: It is suggested that further research on the reliability and useful device in both fields of clinical practice and biomedical research.

Background and purpose: The measurement of direct current (DC) potential on skin area of meridian has recently been adopted to explore the electrophysiological characteristics of meridian system, But there exists two problems to be explained; the entity of the DC potential to be measured and the characteristics of electrode gel interface of measurement system, It is not clear whether the DC potential reflect, at least hypothetically, the entity of meridian, and if there exist any unstable factor in the DC potential measurement system. Methods: In this study, we designed an electronic circuit model of skin and applied known DC potential sources $({\pm}10.75mV,\;0mV)$ to the electrode interface of the skin model. Results: The result showed that the measured DC potential changed according to the time, and the same phenomenon was observed when the electrode gel was replaced with an electric condenser. It is suggested that the measurement of DC potential on electrode gel interface is very difficult and produces unstable values due to the capacity effect of electrode gel. Conclusion: Further studies on the DC potential evaluation in the context of meridian study should consider and bypass this problem.