The Journal of the Korea Contents Association (한국콘텐츠학회논문지)

The Korea Contents Association (한국콘텐츠학회)
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A Study for the Development of Neurofeedback Biosignal Index for Tic Response Supression Test of Tourette's Syndrome

투렛증후군의 틱 반응 억제 시험을 통한 뉴로피드백 생체신호 지표 개발 시론

  • Received : 2022.08.05
  • Accepted : 2022.10.06
  • Published : 2022.10.28
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Abstract

In patients with Tourette's syndrome, a tic occurs when Mu wave synchronization is broken. Conversely, when Mu wave synchronization is achieved, a tick does not occur. When the tic is suppressed, the cognitive control response process is changed, and if the neurofeedback training that adjusts the EEG frequency power is performed with the changed, the patient will be treated autonomously without artificially suppressing the tic. The results of the research test suggest that if the tic patient does not artificially synchronize mu waves in the premotor cortex (Frontal Cortical 3 site), and if EEG control is performed autonomously like neurofeedback training, as a result, tics do not occur. Cognitive control response processes are altered when a subject is inhibited from tics. By training the altered cognitive control with neurofeedback that modulates EEG frequency power, the patient can be treated autonomously without artificially suppressing the tic.Mu-wave synchronizationcan now be added to existing neurofeedback treatment protocols such as SMR reinforcement, theta-beta-wave imbalance correction, and alpha-wave reinforcement. This study will be used in follow-up studies and clinical trials to more scientifically verify the neurofeedback treatment protocol, a treatment for patients with Tourette's syndrome.

투렛증후군 환자에게서 뮤파(Mu wave) 동기화가 깨졌을 때 틱이 발생하고, 그 반대로 뮤파 동기화를 이루면 틱이 발생하지 않는다. 연구시험 결과는 전운동피질(Frontal Cortical 3 사이트)에서 뮤파 동기화를 틱 환자가 인위적으로 하지 않고 뉴로피드백 훈련처럼 자율적으로 뇌파 조절이 이뤄진다면 마찬가지 결과로 틱이 발생하지 않는다는 사실을 시사한다. 피시험자에게 틱을 억제시켰을 때 인지 제어 반응 프로세스가 변경된다. 변경된 인지 제어를 뇌파 주파수 파워를 조절하는 뉴로피드백으로 훈련하면 환자가 인위적으로 틱을 억제하지 않아도 자율적으로 치료가 된다. 연구시험 결과는 뇌 운동영역의 뮤파 통제를 통해 틱이 발생하지 않는 생체신호 지표가 뉴로피드백 훈련의 치료프로토콜이 될 수 있는 단초를 마련하였다. 기존 뉴로피드백 치료 프로토콜인 SMR강화, 세타파-베타파 불균형 수정, 알파파 강화 등에 뮤파 강화를 추가할 수 있게 되었다. 본 연구가 투렛증후군 환자 치료법인 뉴로피드백 치료 프로토콜을 보다 과학적으로 검증하는 후속 연구와 임상시험에 활용될 것이다.

Keywords

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