• 대한안전경영과학회:학술대회논문집
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• 대한안전경영과학회 2002년도 추계학술대회
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• pp.305-319
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• 2002

International capital movement has made progress at global liberalization of finance and foreign exchange, international monetary norm changing into floating exchange rate system, easiness of collection of information and trade at improvement of information communication technology from early of 1970's. Results of empirical test for relation between foreign exchange rate or various determination factors of foreign exchange rate and interest rate are followed by next sentences. First, according to relation between foreign exchange rate and interest rate, correlation for each of variables after OECD entrance is increased. But, long-term ＆short-term interest rate is affected by Hanbo ＆ Kia's bankruptcy, continuous large scale coporates bankruptcy and crisis of foreign exchange. Therefore, financial instability is occured. If portfolio investment fund has been inflow as it is mollified by continuous shortage of foreign exchange and fall of country's credit rating, it is expected to have positive effect for long-term & short-term interest rate from appreciation of won against dollar. Second, results from relation between determination factor of foreign exchange rate and interest rate are followed by next sentences. If surplus of current account and goods account is continued, yield of corporate bond is to be stable. But, margin of surplus is expected to diminish after second quarter 98, and difference between external and domestic interest (after adjusting foreign exchange rate) is to be diminished. And if net inflows of foreign investor's fund (stock and bond) is diminished, it is to have negative effect for yield of corporate bond. According to foreign investor's investment movement of previous years, hedge md were stayed at least during two years in Mexico. It means that sudden capital outflow is not to be happened at Korea. But if external factors from depreciation of yen and China's renminbi are instable, interest rate is expected to increase from capital's outflows. Third, if it is to decrease instability of foreign exchange rate from increase in surplus of future current account, credit rating's upwardness, stability of yen and renminbi, foreign exchange rate is expected to be stable. It is expected to have continuous stability from short-term interest rate to long-term interest rate in this empirical test.

• 한국물환경학회지
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• 제25권1호
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• pp.7-17
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• 2009

Soil and Water Assessment Tool (SWAT) was used to assess the impact of potential future climate change on the water cycle and soil loss of the Daecheong reservoir watershed. A sensitivity analysis using influence coefficient method was conducted for two selected hydrological input parameters and three selected sediment input parameters to identify the most to the least sensitive parameters. A further detailed sensitivity analysis was performed for the parameters: Manning coefficient for channel (Cn), evaporation (ESCO), and sediment concentration in lateral (LAT_SED), support practice factor (USLA_P). Calibration and verification of SWAT were performed on monthly basis for 1993~2006 and 1977~1991, respectively. The model efficiency index (EI) and coefficient of determination ($R^2$) computed for the monthly comparisons of runoffs were 0.78 and 0.76 for the calibration period, and 0.58 and 0.65 for the verification period. The results showed that the hydrological cycle in the watershed is very sensitive to climate factors. A doubling of atmospheric $CO_2$ concentrations was predicted to result in an average annual flow increase of 27.9% and annual sediment yield increase of 23.3%. Essentially linear impacts were predicted between two precipitation change scenarios of -20, and 20%, which resulted in average annual flow and sediment yield changes at Okcheon of -53.8%, 63.0% and -55.3%, 65.8%, respectively. An average annual flow increase of 46.3% and annual sediment yield increase of 36.4% was estimated for a constant humidity increase 5%. An average annual flow decrease of 9.6% and annual sediment yield increase of 216.4% was estimated for a constant temperature increase $4^{\circ}C$.

• 한국토양비료학회지
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• 제12권1호
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• pp.15-23
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• 1979

본(本) 연구의 제(第)1보(報)에서 추출(抽出)된 비옥도(肥沃度) 구성인자(構成因子)의 인자평점(因子評点) 및 현지조사(現地調査)에서 얻은 기타(其他) 환경인자(環境因子)를, 설명변수(說明變數)로 취(取)하고, 현지(現地)에서 청취조사(聽取調査)로부터 얻어진 쌀 수확량(收穫量)을 목적변수(目的變數)로 하여 다중회귀(多重回歸) 분석(分析)과 하야시의 수량화(數量化) 이론(理論) I (Hayashi's theory of quantification No.1)를 적용(適用)하여 생산력을 추정(推定)한 결과(結果)는 다음과 같다. (1) 시료(試料) 개체(個體)에 대하여 얻어진 다섯개의 인자평점(因子評点)을 설명변수(說明變數)로 하여 다중회귀분석(多重回歸分析)을 행(行)한 결과(結果) 중상관계수(重相關係數)가 0.43으로 추정(推定) 정도(程度)가 낮았다. (2) 비옥도(肥沃度) 인자간(因子間)의 상호작용(相互作用)을 고려(考慮)하여 직선회귀(直線回歸) 모델을 이차방정식(二次方程式)으로 변형(變形)시켜 생산력(生産力)을 추정(推定)한 결과(結果) 중상관계수(重相關係數)가 0.59로써 추정정도(推定精度)는 약간 높아졌으나 만족할 수 있는 추정식(推定式)은 얻지 못하였다. (3) 답(畓) 토양(土壤)에서 쌀의 생산력(生産力)을 지배(支配)하는 인자(因子)로서 비옥도(肥沃度)는 물론(勿論) 중요(重要)하지만 다른 환경인자(環境因子)의 영향(影響)도 받을 것으로 사료(思料)되어 비옥도군(肥沃度群), 수분공급(水分供給)의 양부(良否), 토양배수(土壤排水)의 양부(良否), 기후대(氣候帶), 표토(表土)의 점착성(粘着性), 표토(表士)의 결시성(結持性), 토성(土性) 및 하층토(下層土)의 구조발달정도(構造發達程度) 등(等)을 설명변수(說明變數)도 취(取)하여 하야시의 수량화(數量化) 이론(理論) 1을 적용(適用)하여 생산력(生産力)을 추정(推定)한 결과(結果) 중상관계수(重相關係數)가 0.9였고, 이들 인자(因子)들 중(中) 비옥도군(肥沃度群), 수분공급(水分供給) 및 기후대(氣候帶) 인자(因子)가 생산력(生産力)에 크게 기여(寄與)하고 있는 것으로 나타났다.

• 대한환경공학회지
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• 제39권10호
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• pp.568-574
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• 2017

본 연구는 폐목재로부터 organosolv 공정을 이용해서 리그닌을 분리할 때 영향을 미치는 주요 3개의 반응조건(반응시간($X_1$), 산 촉매의 농도($X_2$) 및 반응온도($X_3$))을 리그닌 회수율(y) 기준으로 최적화하였다. 중심합성계획법(central composite design, CCD)에 따라 반응온도 $136.4-203.6^{\circ}C$, 산촉매 농도 0-2.5%, 반응시간 26.36-93.64 분의 범위를 가진 실험계획을 수행해서 2차 모델식 및 최적조건을 수립하였다. 2차 모델식은 $y=-79.89+0.91X_1+9.8X_2-2.54{\times}10^{-3}X_1{^2}-2.11X_2{^2}$와 같이 얻었으며, 결정계수(coefficient of determination, $R^2$) 값은 0.8531으로 10% 이내의 유의수준에서 유의성을 나타냈다. 2차 모델식에 따라 예측되는 최고 리그닌 회수율은 12.46 g/100 g of dry wood이며 이때 최적 반응 조건은 반응온도 $178.2^{\circ}C$, 산 촉매 농도 2.32%으로 나타났다. 폐목재 대상 organosolv 공정에서의 리그닌 수율은 반응온도보다는 산 촉매 농도의 영향이 더 크게 나타났으며 반응시간에 의한 영향은 없는 것으로 나타났다. 모델의 변동성 분석(analysis of variance, ANOVA)에 따르면 리그닌 수율(y)에 대한 모델식의 유의확률은 p<0.001로 높은 유의성을 보였다. 최적조건에서 모델의 재현성을 검증한 결과 모델식이 실제공정을 적절하게 모사한 것으로 나타났다.

• 한국버섯학회지
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• 제19권1호
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• pp.71-75
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• 2021

느타리 1 kg 봉지재배를 통해 살균배지의 주요 화학성과 2주기까지의 버섯 수량간 관계를 분석한 결과, 버섯수확량은 pH, 총질소 함량, CN율과 2차 함수식에서 매우 높은 상관을 보였다. pH는 4.9~5.0의 범위에서, 총 질소량은 2.0~2.2%에서, CN율은 20~22.5에서 가장 높은 수량성을 보였다. 1주기 버섯은 pH, 총질소량 및 CN율과 높은 상관을 보였고 2주기 버섯은 CN율 외에는 상관이 나타나지 않았다. 그러나 수량합계가 1주기 수량보다 3종의 화학성과의 관계에서 모두 더 높은 상관이 나타났다. 그리하여 본 연구에서 배지의 pH, 총질소 함량 및 CN율은 전 수확기간에 걸쳐서 버섯수량에 큰 영향을 미친다는 결론을 얻을 수 있었다.

• 폴리머
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• 제29권4호
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• pp.369-374
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• 2005

본 실험에서는 레몬 오일을 함유한 알긴산 칼슘 마이크로캡슐을 에멀션-내부 젤화법으로 제조하였으며, 방출실험을 통하여 아로마테라피의 가능성에 대해 살펴보았다. 적외선분광분석(FT-IR)과 시차주사열량계(DSC)를 통해 레몬 오일의 봉입 여부를 확인하였고, 제조된 마이크로캡슐의 직경 및 형태를 주사전자현미경(SEM)으로 관찰하였다. 제조된 마이크로캡슐은 평균 $4\~7$um직경 및 $50\~85\%$의 캡슐화를 보였으며, $37^{circ}C$에서 적외선 수분계(IMDB)를 통한 방출실험 결과. 알긴산 및 $CaCl_2$의 농도가 증가할수록 가교밀도가 증가하므로 레몬 오일의 방출률이 감소함을 관찰할 수 있었다. 또한, 물리적 압력을 통한 방출실험을 실시함으로써, 캡슐벽의 붕괴와 방출속도가 외부적인 요인에 의해 방출속도를 제어할 수 있음을 확인하였다.

• Journal of Microbiology and Biotechnology
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• 제8권1호
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• pp.81-88
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• 1998

The determination of appropriate parameters and parameter conditions is very important for the optimization of production of target materials. Taguchi's method has been used widely as the basis for development trials and optimization during industrial process design. Reaction variables which influence product yield are easily determined and their effects are revealed by just a few reactions, negating the need for extensive experimental investigation. There are usually some factors that are responsible for variations in process characteristics, so called noise factors. Controlling noise factors is very costly and difficult or impossible. Taguchi's experimental design method was examined to determine the control factor's level that is less sensitive to the changes in environmental conditions and other noise factors without control of noise factors. In this study, optimization of lipase-catalyzed production of lysophosphatidic acid (LPA) which has various physiological functions was performed by Taguchi's method. We obtained LPA yields ($66.5\%$) with low variance (5.32) at 400 RPM, molar ratio of 40 : 3 (mol) (fatty acid: G-3-P), 48 h, and $50^{\circ}C$. Thus, bioactive LPA with a desired fatty acid moiety could be produced with high yields and low variance despite various environmental noise factors.

• Journal of Microbiology and Biotechnology
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• 제28권6호
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• pp.902-908
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• 2018

Optimization of the culture medium to maximize menaquinone-7 (MK-7) production by Bacillus subtilis strain KCTC 12392BP in static culture was carried out using statistical experimental methods, including one factor at a time, fractional factorial design, and response surface methodology (RSM). Maltose (carbon source), tryptone (nitrogen source), and glycerol (activator) were identified as the key medium components for MK-7 synthesis by the fractional factorial design, and were selected for statistical optimization by RSM. The statistical analysis indicated that, in the range that was studied, maltose, tryptone, and glycerol were all critical factors having profound effects on the production of MK-7, with their coefficients for linear and quadratic all significant at the p < 0.05 level. The established model was efficient and feasible, with a determination coefficient ($R^2$) of 0.9419. The predicted concentrations of maltose, tryptone, and glycerol in the optimal medium were determined as 36.78, 62.76, and 58.90 g/l, respectively. In this optimized medium, the maximum yield of MK-7 reached a remarkably high level of $71.95{\pm}1.00{\mu}g/ml$ after 9 days of static fermentation, which further verified the practicability of this optimized strategy.

• The Korean Journal of Physiology and Pharmacology
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• 제19권1호
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• pp.35-42
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• 2015

In cardiovascular disorders, understanding of endothelial cell (EC) function is essential to elucidate the disease mechanism. Although the mouse model has many advantages for in vivo and in vitro research, efficient procedures for the isolation and propagation of primary mouse EC have been problematic. We describe a high yield process for isolation and in vitro culture of primary EC from mouse arteries (aorta, braches of superior mesenteric artery, and cerebral arteries from the circle of Willis). Mouse arteries were carefully dissected without damage under a light microscope, and small pieces of the vessels were transferred on/in a Matrigel matrix enriched with endothelial growth supplement. Primary cells that proliferated in Matrigel were propagated in advanced DMEM with fetal calf serum or platelet-derived serum, EC growth supplement, and heparin. To improve the purity of the cell culture, we applied shearing stress and anti-fibroblast antibody. EC were characterized by a monolayer cobble stone appearance, positive staining with acetylated low density lipoprotein labeled with 1,1'-dioctadecyl-3,3,3',3'-tetramethyl-indocarbocyanine perchlorate, RT-PCR using primers for von-Willebrand factor, and determination of the protein level endothelial nitric oxide synthase. Our simple, efficient method would facilitate in vitro functional investigations of EC from mouse vessels.

• 예술인문사회 융합 멀티미디어 논문지
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• 제7권8호
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• pp.305-314
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• 2017

Clustering is a method that collects data objects into groups based on their similary. Performance of the state-of-the-art clustering methods is different according to the data characteristics. There have been numerous studies that performed experiments to compare the accuracy of the state-of-the-art clustering methods by applying various kinds of datasets. A common problem of these studies is that they only consider clustering algorithms that yield the most accurate results for a particular dataset. They do not consider what factors affect the execution time of each clustering method and how they are affected. Nevertheless, execution time is an important factor in clustering performance if there is no significant difference in accuracy. In order to solve the problems of the existing research, through a series of experiments using various types of datasets, we compare the accuracy of four representative clustering methods. In addition, we perform practical clustering performance comparisons by deriving time complexity and identifying factors that influences to its performance.