• Title/Summary/Keyword: well-being behaviors

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Human Embryonic Stem Cells Co-Transfected with Tyrosine Hydroxylase and GTP Cyclohydrolase I Relieve Symptomatic Motor Behavior in a Rat Model of Parkinson′s Disease

  • Kil, Kwang-Soo;Lee, Chang-Hyun;Shin, Hyun-Ah;Cho, Hwang-Yoon;Yoon, Ji-Yeon;Lee, Gun-Soup;Lee, Young-Jae;Kim, Eun-Young;Park, Se-Pill
    • Proceedings of the Korean Society of Developmental Biology Conference
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    • 2003.10a
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    • pp.101-101
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    • 2003
  • Main strategy for a treatment of Parkinson's disease (PD), due to a progressive degeneration of dopaminergic neurons, is a pharmaceutical supplement of dopamine derivatives or ceil replacement therapy. Both of these protocols have pros and cons; former exhibiting a dramatic relief but causing a severe side effects on long-term prescription and latter also having a proven effectiveness but having availability and ethical problems Embryonic stem (ES) cells have several characteristics suitable for this purpose. To investigate a possibility of using ES cells as a carrier of therapeutic gene(s), human ES (hES, MB03) cells were transfected with cDNAs coding for tyrosine hydroxylase (TH) in pcDNA3.1 (+) and the transfectants were selected using neomycin (250 $\mu /ml$). Expression of TH being confirmed, two of the positive clone (MBTH2 & 8) were second transfected with GTP cyclohydrolase 1 (GTPCH 1) in pcDNA3.1 (+)-hyg followed by selection with hygromycin-B (150 $\mu /ml$) and RT-PCR confirmation. By immune-cytochemistry, these genetically modified but undifferentiated dual drug-resistant cells were found to express few of the neuronal markers, such as NF200, $\beta$-tubulin, and MAP2 as well as astroglial marker GFAP. This results suggest that over-production of BH4 by ectopically expressed GTPCH I may be involved in the induction of those markers. Transplantation of the cells into striatum of 6-OHDA- denervated PD animal model relieved symptomatic rotational behaviors of the animals. Immunohistochemical analyses showed the presence of human cells within the striatum of the recipients. These results suggest a possibility of using hES cells as a carrier of therapeutic gene(s).

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An Experiential Analysis on Scolding behavior of Elementary School Teachers (꾸중에 대한 초등교사의 체험분석)

  • Kim, Jong-Sook
    • The Korean Journal of Elementary Counseling
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    • v.6 no.1
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    • pp.95-116
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    • 2007
  • This thesis is aimed to understand when and how elementary teachers scold their students and to explore any common psychological factors shown in the process. In order to produce the meaningful results of the research, applied is experience-based analysing method which expectedly leads to discovering psychological cause and effect occurring when school teachers scold students. 11 teachers of elementary school, including me the author, have joined as co-researchers to solve the next two issues and I made guidelines for the analysis. Given that co-researchers are locally scattered, they were grouped into three and in the mean time, analysis on scolding during 4 meeting sessions were made. The results of research problems are as follows. First issue: What common psychological factors exist in when and how teachers scold students? Common factors in 'when' part include three cases: teachers discovering the factors hindering student's desirable growth, noticing the class rules and peaceful communities are broken, or experiencing humiliating remarks and annoying behaviors and In "how' part, on the other hand, teachers speak up in a stronger voice or raise their tone to point out student's wrongdoing and give students a stoic and fierce look. Second issue: What psychological development takes place in scolding? Teachers who participated in this scolding experiment have experienced' feeling responsible and upset'. Feeling responsible is highly likely to be interpreted to result from the idea that teachers supposedly support students to grow into well-functional person in society. Meanwhile, feeling upset or even humiliated is caused by the frustration when they find their authority and dignity Ignored and damaged. The phases teachers go through during the scolding are: recognizing scold-inviting situation-> interpreting clues deserving enough to scold-> being aroused into the feelings-> deciding how to respond-> executing decision-> dealing with emotion. This thesis has distinctive qualities from existing ones in that the research focuses on agonies and conflicts faced with school teachers in class. On top of that, it is noted that this thesis meaningfully enables to realize teachers' psychological mechanism activated from scolding and to provide teachers with opportunities to see themselves more proper perspectives. However, there still remains some reservation since I had rather short period of time to collect data and we, co-researchers, had meeting sessions. To compensate for the possible shortcomings shown in this thesis, further research is expected to be followed to perform a practical analysis.

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Literature review on maternal-fetal interaction (모-태아 상호작용에 대한 문헌고찰)

  • Cho, Kyeul-Ja;Kim, Jung-Soon
    • Korean Parent-Child Health Journal
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    • v.3 no.2
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    • pp.49-66
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    • 2000
  • Pregnancy is a task of creation in which a women mobilizes her self and the resources available to her in the generation of a new person. Through the pregnancy, a mother has formed the new human relationship with a fetus. Maternal-fetal relationship is considered one of mechanism making the relationship of mother and child. It is important to well-being of mother and fetus, too. The earliest interaction between a mother and her child is during prenatal period. Maternal-fetal dyad is unique and perceived interactions with the fetus make the pregnancy real for the mother. Maternal behavior is "instinctive" and is formed in early childhood by copy of the mother. But, Rubin argues that this behavior is an open intellectual system rather than a prepackaged bundle of traits. There is openness to new learning and a high value placed on knowing which occurs with silent organization in thought. Thus, nurses and other health professionals provide prenatal care that optimally is part of the environment in which the maternal-fetal dyad develops. Thus it is appropriate for nurses to increases their understanding of the dyad and to explore ways to enhance its development. This study focusses on the interaction ability and response of fetus, and the maternal-fetal interaction. The research of fetal responses that involve physiological changes and motor movement have been shown to coccur to both external sensory stimuli and to maternal emotional states. The fetus does also have sensory capacity to be aware of some maternal behaviors, and the motor ability to respond in a way the mother can notice. Thus, very rudimentary interactions appear to be possible. Maternal awareness of fetal activity was supported by several studies. More interesting to the present study are description of maternal-fetal interaction and the finding that there appear to be levels of sensitivity to the fetus involved in maternal-fetal interactions. First, recognition comes that the fetus is separate from the maternal self. Next, the fetus engages in. Lastly, the parent may describe active interaction with the fetus, believing that mother and fetus are communicating on a meaningful level. Several interventions, developed to promote more active interaction between mother and fetus, have been reviewed. In general, the parents were taught to stimulate the fetus and to notice the fetus' responses. This type of intervention might increase the mother's sensitivity to her unborn baby, and she may have a head start toward learning how to res pond sensitivity to the newborn infant. Research In the area of maternal-fetal interaction is scarce. Sensitive behavior is construed as an appropriate and timely response to a signal of need from another person, but no such signal of need can be claimed regarding the fetus. The highest level of maternal-fetal interaction, therefore, might be based more on maternal representations of the imagined fetus than on factual evidence of fetal participation.

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Assessment of Job stress and Psychosocial stress level using Psychosocial health measurement tool in dental technicians (사회심리적 건강측정도구를 이용한 치과기공사의 스트레스 평가)

  • Kim, Wook-Tae;Han, Tae-Young
    • Journal of Technologic Dentistry
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    • v.31 no.3
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    • pp.67-85
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    • 2009
  • This study aims to provide the research for dental technician's stress prevention and management with basic materials by understanding dental technician's psychosocial stress level and examining relevant factors. The subject of this study is 255 dental technologists who work mainly in Seoul Gyeonggi district for a month of April of 2009 and I conducted cross-sectional study through self administered survey. The contents of survey include general feature, occupational feature, health behavior feature. I used Karasek's Job Content Questionnaire, JCQ and Psychosocial well-being index, PWI-SF as means of measurement. To compare the level of dental technician's psychosocial stress, I conducted t-test and ANOVA and I measured the factors that are related with psychosocial stress symptom with step by step multiple regressive analysis. According to the result of Cronbach's a value which is yielded to verify the reliability of means of measurement, the reliability of concept is sufficient. The detailed result of this study is as follows. 1. According to the result of analyzing the stress symptom in accordance with general feature and occupational feature, those dental technologists who are older and not married, graduate from junior college, have lower position, work at university hospital or general hospital show lower stress(p<0.05). There is no difference in the level of psychosocial stress with regard to duty related feature, period of service, daily average working hours, monthly average pay. 2. With regard to health behavior feature, those dental technologists who control weight better and have meal more regularly show lower stress(p<0.05). Those dental technicians who smoke, drink liquid and take a suitable sleep show low stress but the difference does not have significance statistically. 3. With regard to the factors of stress in the workplace, those dental technicians who have lower duty related requirement, have higher duty related control ability, have higher social support, have less instability of employment and have less workload and physical burden show lower stress(p<0.05). 4. According to the result of analyzing the factors that influence dental technologist's stress symptom, social support has the most enormous influence on stress symptom. Unstable employment, regular exercise, regular eating, daily average sleeping hours and technological capacity are also important in this order. According to the result of this study, those dental technicians who have higher social support, less instability of employment, do exercise more regularly, take enough sleep more soundly and have higher technological capacity show lower psychosocial stress symptom. Therefore, to adjust appropriately the dental technician's stress and properly maintain and improve the dental technician's mental health, effective management plan that enables dental technicians to maintain smooth human relationships for dental technicians should be sought. In addition, heath education and health management for dental technicians should be given more thoroughly so that they can establish desirable health behavior in daily life.

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The Effects of the Benefit-Sharing Activities through Dynamic Trust on Recontract Intention in Foods-Service Franchisers (외식 프랜차이즈 사업의 성과공유활동이 동태적 신뢰를 통해 재계약의도에 미치는 영향)

  • Kim, Ha-Kyung;Park, Hyeon-Suk
    • Journal of Distribution Science
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    • v.14 no.7
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    • pp.101-114
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    • 2016
  • Purpose - The aim of this study is to investigate the benefit-sharing activities. They affect contract renewal intention between franchisers and franchisees that are linked through a contract with the intention of building their relationship from the level based on dynamic trust. This study will show a new approach on qualitative growth and consolidation of competitive power and may well be able to suggest practical ways to strengthen directions in the field of franchise industries. Research design, data, and methodology - In this study, based on literature review, we separated logistical-supporting activities and non-logistical-supporting activities from benefit-sharing activities. We modeled how benefit-sharing activities influence contract renewal intention of franchisees by dynamic trust. In particular, considering the possibility of trading concepts and characteristics of trust between providers opportunistic behaviors was defined as variables, depending on the situation and dynamic characters reveal their relationship trust concept. That is, dynamic trust having the possibility of changing depending on opportunistic risks and interdependencies by Lewis & Weigert(1985, 2012) was classified into transitional-based trust, calculated based trust, relational-based trust and balance-based on trust. The total of 104 samples from domestic franchisees being with franchisees were collected by using a structural composed questionnaire. Results - The results are as following. Benefit-sharing activities in logistical supporting activities appeared to affect the multidimensional concept of transitional trust, calculated based on trust, relationship-based trust and balance based on trust dynamic trust with all-defined impact. Non-logistical supporting activities appeared to affect significantly the positive (+) to the dynamic trust concept except transitional trust. Lewis & Weigert(1985; 2012) have proposed a dynamic confidence calculated from relations within-based trust relationship based on trust appears to affect the significant positive (+) to the balance-based confidence transactions confidence mechanism of the system side in the verified relationship. Finally, a relationship based on trust and confidence in the balance based on the Influence of dynamic renewed confidence showed significantly affect the positive(+). In particular, the balance based trust showed the acts as a mediating factors between relational trust and confidence and renew calculated. Conclusion - From the above these results, the significance from this study is as following. First, the proposed activity is to share and validate the approach by identifying the potential in the relationship from the contract with building dynamic trust, and one of the ways from the franchise headquarters and affiliated merchants mutual growth through win-win cooperation in sharing activities. Next, the dynamic segmentation confidence to suggest the possibility can be broken down over the validity and reliability test for each concept. In addition, by identifying the relationship between the dynamic level of confidence granular multi-dimensional concept, to determine the level of trust with a dynamic relationship between risk and interdependencies can be possible in franchise industries. In order to maintain and develop their mutual relationship, franchise industries should propose confidence-building steps to promote their quality improvement.

A Study on the Competitive Strategy of Department Store for Sustainable Development (지속가능한 성장을 위한 백화점의 경쟁전략에 관한 연구)

  • Jin, Chang-Beom;Park, Chul-Ju;Youn, Myoung-Kil
    • Journal of Distribution Science
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    • v.15 no.3
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    • pp.73-80
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    • 2017
  • Purpose - Since Korean distribution market was opened, the domestic environment in department stores has been changed by the pattern of consumption and consumer need based on income classes. As multilateral Free Trade Agreement (FTA) accelerates opening markets, the scale of circulating capital has become bigger. Large-scale commercial facilities have developed quickly as a form of a large shopping center, thus, the matter of choice and securing market area became an important valuable in this trend. Moreover, multi-complex space has been proposed as the goal of successful business with promoting the public benefit. Research design, data, and methodology - This research studied consumer behavior using data about the life style and sales of consumers, not statistical data or survey as previous studies. This research tried to find the differentiation in complex cultural space with consumption behavior of department store. Results - As the structure of society and culture was getting diverse and complex, economic growth and development with such diversity and complexity improved consumers' quality of life. The changes of consumer life style are quite natural like human instinct. Department stores have activated retail business with the products of accumulated technology. Moreover, they have created the space of consumption and culture. Because of these social and environmental changes, department stores are being developed as Multi-functional spaces as well as sale places considering the strategies of department and the changes of consumers' purchasing behaviors. Conclusions - Urban culture complex is a landmark standing for the culture era of 21st century. It has provided an opportunity for consumers to enjoy culture, and has been an important factor to improve company images. Based on these roles and needs, expectancy effects are related with consumer preference and space preference, and the attitude toward companies. Moreover, the expectancy effects from those relationships are getting bigger and bigger. We should respect nature, a characteristic of Korean architecture, maintain visual continuity that harmonies with nature in the development of the complex space of the domestic department stores, and should take significance in the development of the complex cultural space in the direction of feeling the hierarchy of the space to obtain the visual pleasure with the artificial structure.

Effects of Philanthropy Education on Elementary School Students in Korea : Analysis Using a Multiple Convergence Model (나눔교육을 통한 아동의 변화 연구: Multiple Convergence Model의 적용)

  • Kang, Chul-Hee;Kim, Mi-Ok;Lee, Jong-Eun;Lee, Kyoung-Eun
    • Korean Journal of Social Welfare
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    • v.59 no.4
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    • pp.5-34
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    • 2007
  • This study explores the effects of philanthropy education for elementary school students by using a mixed method. To examine the effects of philanthropy education, two different approaches in research methods are conducted with different data collected from different target groups on the same phenomenon: a) experimental designs to analyze students' change(prosocial behaviors) by philanthropy education program performed in a summer camp(43 participants) and elementary schools(162 students); and b) qualitative analysis on students' changes in perceptual, attitudinal, and behavioral aspects by students' diary and memorandum(66 participants) and intensive interviews with teachers(5 teachers) and parents(4 mothers). The analysis of both quantitative and qualitative results shows that philanthropy education has effects on students' changes in diverse aspects including prosocial behavior. First, the results of quantitative analysis show that in every component of the prosocial behavior such as helping, being kind, empathizing, sharing, protecting, and cooperating, students have positive changes after philanthropy education. Such changes are statistically significant as well. Second, the results of qualitative analysis show that students after having philanthropy education display positive changes in diverse aspects. Particularly, the quantitative results are converged with the qualitative results from students, parents, and teachers. On the other hand, unique finding from qualitative analysis is that students after having philanthropy education can have fundamental changes in their personality. Such a change is commonly confirmed by students, parents, and teachers. This study makes it possible to compare results or to validate, confirm, or corroborate quantitative results with qualitative findings on the effects of philanthropy education for students.

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A Study on the Determinants of Purchasing Decision Making for Effective Branding Strategy: Focusing the Medicine Treatment in Infantile Obesity (효과적인 브랜딩 전략을 위한 소비자 구매의사 결정 요인 분석: 소아비만 치료제 유통시장을 중심으로)

  • Park, Mun-Seo;Kim, Hyung-Joon;Lee, Sang-Youn
    • Journal of Distribution Science
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    • v.9 no.3
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    • pp.55-64
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    • 2011
  • This study is important in its focus to find key clues in the marketing strategy, consumer behavior, and communication processes that define the infantile obesity market. The study, the first of its kind, surveyed a target audience, purchasing group, and housewives in their quest to determine purchasing decisions and effective branding strategy planning for the infantile obesity market. Another key component of the study was to focus on the key direct and/or indirect distribution channels for the subject market. Recently, obesity has emerged as a major social concern; some studies show that the onslaught of an adverse eating culture in Korea emanates from the prevalence of fast-food dining establishments. Obesity among children leads to adult obesity, especially if the young people's parents are overweight; notably, if either one or both of the parents are obese, the percentage of young people eventually being obese is approximately 80 to 85 percent. Because obesity is the cause of many major health concerns later in life, the struggle for a healthy life is considerably adversely affected by parents' consumer behavior. Infantile obesity, resulting in adult obesity, is also an important national economic and social issue. The sizable direct and indirect economic costs, as well as the tremendous social costs of obesity, cannot be overstated. Effective food branding and advertising centered on food preferences and dietary behaviors, especially to children, creates an effective marketing effort that, ultimately, leads to positive results. Thus, the purpose of this study is to demonstrate that the treatment of childhood obesity in Korea, through the activation of a brand and retail market, can effectively solve social and economic problems that result from infantile and childhood obesity. In this study, obesity markets and distribution channels in the purchase decision-making factors determining factor based on it effective inspection and branding strategies and brand marketing communications strategy proposed measures contribute to the obesity drug market and further enable the childhood obesity problem is intended to assist in solving.

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A Study on Expression of the Film (2019) : Focusing on Genre-Shifting Characters and Actors' Acting (영화 <기생충>(2019)의 표현성 연구 : 장르를 변주하는 캐릭터와 배우의 연기를 중심으로)

  • Lee, A-Young
    • Journal of Korea Entertainment Industry Association
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    • v.14 no.6
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    • pp.77-89
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    • 2020
  • The film "Parasite" portrays Korea's history and its present in a space that clearly represents the real world's hierarchy as a vertical structure. It demonstrates the problems of an insurmountable reality and the elements of various conflicts occurring below the surface of Korean society through a complex mix of human emotions and relationships. The most realistic yet unrealistic characters cross boundaries between being victims and perpetrators, defamiliarizing ordinary scenes from everyday life through their small mistakes, strange obsessions, bizarre behavior, anxious psychology, and desperate struggles. This study analyzes the expression of the film "Parasite" through its characters with the belief that the film expresses director Bong Joon-ho's consistent cinematic philosophy of taking reality beyond the traditional rules of film genres. By doing so, Bong creates a feature of the expression that shifts genres as the characters' personalities amplify related behaviors, conflicts and questions, and that this is the core of the unique nuance and distinct humor of this film. In addition, the personalities of the characters interact with all the film's elements (cinematic techniques, space, props, etc.), evoking effects of various meanings, which are transmitted through the actors'images and acting. In this respect, the study analyzes how the actors were cast in order to realistically reproduce the characters of the actors, how their acting was harmonized with the film's elements, and its features as well as how they were expressed.

A qualitative study on the adjustment process of families adopting an older child (연장입양가족의 적응과정에 대한 질적 연구 : 주 양육자인 입양모의 입장에서)

  • Chung, Ick-Joong;Kwon, Ji-Sung;Min, Sung-Hye;Shin, Hye-Won
    • Korean Journal of Social Welfare Studies
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    • v.42 no.1
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    • pp.399-432
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    • 2011
  • The purpose of this study is to understand the adjustment process of families adopting an older child, and to generate a substantial theory. To achieve this purpose, we conducted in-depth interviews with mothers adopting an older child and analyzed data with qualitative analysis approach. From the analysis, theoretical model has been made, and the model includes the adoptive families' diverse experiences, barriers to adjustment as well as resources and strategies that they mobilized and used for smooth adjustment. Their experiences in the process of adjustment consisted of five phases: unfamiliar meeting, shock, fighting alone without support, control, and stability. Barriers to adjustment process were composed of adoptees' problem behaviors, loss of time, lack of preparation, lack of experiences, repetition of the vicious circle, withstanding alone, improper resources, lack of support, and being criticized. Resources and strategies that families adopting an older child utilized were individual resources and ability such as rearing experiences, intellectual ability, willingness, belief, and perspective change; family system such as spouse and other offsprings; informal support system such as extended families, relatives, friends, neighbors, and other families adopting an older child; formal resources such as adoption workers and helping professionals. From our results, we suggested policy and practice guidelines to help adjustment experiences for families adopting an older child.