• Journal of Korean Physical Therapy Science
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• v.13 no.2
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• pp.99-119
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• 2006

Endothelin (ET) is a 21 amino acid peptide with multifunctional effects on the vasculature as well as a variety of other cell types such as respiratory, gastrointestinal, urogenital, endocrine, central nervous systems, and others. Endothelin has emerged as a modulator by autocrine and paracrine actions for many cellular activities, including vasoconstriction, cell proliferation, hormone production, neurotransmitter and/or neuromodulator. The endothelin family consists of three closely related peptides, ET-1, ET-2, and ET-3 derived from separate genes, such as chromosome 6, 1, and 20, respectively. ET-1 is the predominant isoform produced in the cardiovascular system and about which most is known. Endothelin receptors are seven-transmembrane GTP-binding protein-coupled receptors, which are classified into endothelin-A (ETA) and endothelin-B (ETB) receptors. Interestingly, recent evidence is accumulating to suggest that ET -1 may contribute to a variety of pain states such as allodynia and hyperalgesia in animals and humans. Therefore, in this review the biological characteristics and contraction-related mechanism of endothelin-1 in mammalian cells will be summarized. Especially, we focus on multifunctional roles for ET-1 in noxious stimulation-induced pain for the study of pain specialized physical therapy.

• Journal of Technology Innovation
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• v.25 no.3
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• pp.51-82
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• 2017

In terms of both economic growth and social welfare, this paper discusses the optimal proportion and size of basic research budget by adding knowledge stock to an endogenous growth model. On the basis of the modified endogenous growth model, this paper derived an equation that consists of kinds of parameters and suggested this equation as a criterion for determining whether allocated basic research budget has been appropriate. This paper also found that the theoretical optimal ratio between government investment spending and investment in basic research is equal to the ratio between the partial elasticity of output with respect of public capital stock and the partial elasticity of output with respect of knowledge stock. In addition, after the required parameters were specified based on precedent literatures, this paper estimated an optimum size of the basic research budget using the theoretical optimal ratio with official statistical records and compared the estimated size to its actual size. This paper therefore is expected to contribute to budget planning and allocation regarding establishing basic research policy, because the results of this paper presents a useful criterion for optimum level and an approximate size of investment in basic research. However, it should be noted that although the optimal solution is optimal in a economic sense, it may not be the best solution from a practical perspective.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.51 no.2
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• pp.188-194
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• 2015

The powered purse seine fishery is an important fishery accounting for 19.4% of adjacent water fishery production in Korea, and the commercial fishing is associated with high rate of fatal and non-fatal occupational injury. The hazard analysis for the fishermen's safety of offshore large powered purse seiner was conducted to serve as a basic data for improving the healthy and safe working environment of fishermen using fishermen's occupational accidents of the national federation of fisheries cooperatives (NFFC) in 2013 (n=583). As a result, the occupational accident occurrence rate of this fishery was 182.6‰ in all industries 30.9 times the rate of that. In addition, death and missing rate was found to have a very serious level management to 25.1‰ in all industries of death of 17.5 times. The accident occurred in 72.3 to 85.8% was happened at sea. The others, slipping and struck by object etc occurred more frequently in order in the frequency of accident occurrence pattern. However, the occurrence rate of death and missing did not match the frequency of accident pattern. In other words, slipping occurred frequently higher while death and missing risk was not high. And the contact with fishing gear and fall in the waters was low while death and missing risk was high. The results are expected to contribute for identification and assessment of safety hazard occurred in offshore large powered purse seiners.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.4
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• pp.573-586
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• 2016

This study attempted to look into the effects of the job environment and job esteem on job satisfaction in the field of skin beauticians. To achieve this, a survey of their characteristics, job environment, job esteem and job satisfaction was carried out on 470 women in their 20s~50s working at skin care shops in the Seoul and Gyeonggi areas. First, it was found that the effects of the working environment on their vocational satisfaction, sense of belonging, level of contribution, wages and welfare, which are sub-factors of job satisfaction, are relatively high. This result shows that it is important to ensure proper resting facilities and resting areas. Second, it was shown that the higher the social evaluation, self-(implicit) assessment, future value, and self-fulfillment orientation, the higher the sub-factors of job satisfaction. This means that it is important to treat skin beauticians as professionals in order to improve their social recognition. The sub-factors of job environment-working conditions, organizational environment and job stability, and sub-factors of job environment-social evaluation, self(intrinsic) evaluation, future value and self-achievement orientation, had a major effect on the sub-factors of job satisfaction, respectively. Together with the general improvement in the sub-factors of job environment, the future value, as well as social evaluation, self(intrinsic) evaluation and self-achievement orientation, which together constituted the current value of job esteem, were the major factors affecting job satisfaction. Consequently, this study hopes to contribute to the development of the skin beauty industry by providing basic data on personnel management for skin care managers to improve skin beauticians' job satisfaction.

• Health Policy and Management
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• v.21 no.1
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• pp.93-114
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• 2011

This study was conducted to identify college students' supportive attitude toward the elderly and their awareness of the socialization of care for the elderly, since they will have the responsibility for and the support of the aged society in the near future. This study was also conducted to analyze the factors which affect the socialization of elderly care, and to contribute to building a care system which promotes ahealthy and happy lifestyle for the elderly. After conducting a survey of 1,100 students from13 universities around the entire country, I have analyzed 1,089 data forms, and omitted 11 data entries which had errors or were not answered. 1. Those surveyed are 1,089 students from 13 universities around the entire country. Regional distributions are as follows : 263 students from 4 universities in Daegu and Kyongsangbuk Do(24.2%), 291 students from 3 universities in Busan and Kyongsangnam Do(26.7%), 272 students from 2 universities in Jeolla Do(25.0%), 263 students from 4 universities in Seoul and Gyeonggi Do. Males are 51.7% and females are 48.3% of these students. 2. Instrumental supportive sense level is high in men and emotional supportive sense level is higher in women. Also emotional supportive sense is higher in groups of those having more family members and coming from agricultural regions. 3. The sense of living with aged parents is higher in those living with grandparents than those living separate. The sense of living with sons and daughters after aging is stronger in the students from the Science and Engineering Departments than in the Social and Human Sciences Departments; also higher for men than women. 4. Recognition of elderly care socialization is higher in those from Social and Human Sciences Departments than from Science and Engineering Departments; higher in the case of upper classmenand aged groups, groups having fewer family members than more family members, and in the case of living separated from grandparents. 5. The factors affecting the sense of living with grandparents were family cohesion and instrumental supportive sense. The factors affecting the sense of elderly care socialization were family cohesion, instrumental supportive sense, and emotional supportive sense. From the results it is concluded that to insure a healthy and happy lifestyle for aged people, elderly care socialization offered by society and the country must provide desirable, appropriate care services based on the centralized support system of the family. In order to do this, we propose that elderly care needs inter-family and inter-generational fusion programs to improve family cohesion and care recognition. Also, elderly care is in urgent need to build a strong Family and Health Welfare System for care socialization.

• Herbal Formula Science
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• v.27 no.4
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• pp.269-284
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• 2019

This study was to investigate whether cultivated ginseng (CG), cultivated wild simulated ginseng (CWG) and cultivated red ginseng (CRG) extracts influences on the obesity. The saponin contents of 3 kinds of ginsengs were analysed by HPLC-ESI-TOF-MS. Total saponin contents were determined in CG on the most contents and since red ginseng has the highest PD (protopanaxadiol type) / PT (protopanaxatriol type) ratio, there may be differences between ginseng, wild ginseng, and red ginseng with respect to their pharmacological effects. Male C57BL/6J mice were fed a normal diet(N), HFD (60% Kcal fat, C), HFD with CG, CWG and CRG extracts (800 mg/kg) for 5 weeks. We observed change of total body weight, degree of hepatic lipid accumulation and immunohistochemical change of GLP-1 and insulin-secreting cells. Also this study attempts to use the physiological analysis method to analyze the changes of blood lipids, insulin and leptin concentration. The change of body weight and size of accumulated lipid droplets in liver lobules decreased in all of the experimental groups than the control(C) group. In the pancreas, the immunohistochemical density of insulin-secreting cells were significantly stronger in the CWG and CRG than C group. The levels of serum insulin and leptin significantly decreased 55.6%, 54.3% respectively in CWG and CRG. The changes of triglyceride, total cholesterol in serum decreased in CRG than the C group. Obesity related CG, CWG and CRG extracts might have contribute to improvement of obesity by regulating the levels of blood lipids and biochemical indicator of fat accumulation.

• Journal of the Korea Society of Computer and Information
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• v.20 no.6
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• pp.117-126
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• 2015

Multi-Cultural Family Support Act means that to lead a stable family life in Korea by improves the quality of life for members of multi-cultural families through the extensive support and ultimately it refers to a law designed to contribute to the integration between society and them. This Law was newly enacted as Law No. 8937 in March 21, 2008. And through the six times amendments it improve the part of the lack also now in February 18, 2015, some amendments are submitted by Jasmine Lee with 12 lawmakers. Now in 2015, the number of foreigners who living in Korea are beyond 150 million and it can see that has entered into a full-fledged multi-cultural society. And it can place a greater significance that had laid the foundation of the various support policies to lead a stable family life for members of multi-cultural families. However, the problem that much current law which associated with the Multi-cultural Family Support Act cannot accept the social changes has emerged. Thus, in this paper try to present a legislative plan that can respond appropriately to the real world through the analysis of it.

• Journal of rehabilitation welfare engineering & assistive technology
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• v.10 no.1
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• pp.9-18
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• 2016

This study reported a case study that showed educational usefulness of SAFMEDS (Say All Fast a Minute Every Day Shuffled) on the improvement of Fluency. The participants were 3 experts with special teacher and speech and pathology, who enrolled a graduate level course, Research in Children with Autism Spectrum Disorder. The SAFMEDS strategy was employed as a study tool for the participants to acquire fluent verbal repertoires related to the key terminologies of Skinner's (1957) analysis of verbal behavior, list 60 pairs of terms. The participants developed 60 term flash cards which presented a target term on the front of the card, and its definition on the back. During the intervention, the participants were required to see the definition and says its term. The results of this study indicated that the SAFMEDS was effective to improve participants' fluent verbal repertoires in terms of both accuracy and fluency. The results of this study would be able to contribute for education professionals to improve certain target operant's accuracy and fluency.

• Journal of Digital Convergence
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• v.13 no.7
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• pp.223-228
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• 2015

This study aims to verify the effect of the strength note program by comparing and analyzing the effect of the strength note program on self-esteem and self-efficacy of university students in Convergence Age. This study targeted 70 male and female university students in G area and the subjects were asked to find their and other people's positive characteristics or strengths once a week and record them. For analysis of the collected data, frequency and percentage analysis and paired-t-test were conducted using SPSS WIN 20.0. As the result, the strength note program significantly influenced the improvement in self-esteem and self-efficacy of university students. This result demonstrates the necessity of the strength note program for improving self-esteem and self-efficacy of university students. Therefore, there is a need to provide a specific and systematic strength note program to help university students get over diverse problems. It is considered that this will help mental health, academic achievement and career search of university students and contribute to the enhancement in happiness and the quality of life. Also it will be the basis for future longitudinal studies through interdisciplinary convergency research.

• The Journal of the Korea Contents Association
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• v.12 no.6
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• pp.78-91
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• 2012

The Terrestrial DTV service compliant with ATSC has been advancing for years. In KBA(Korean Broadcasters Association), a multi-channel service was broadcasted on air during the period of the 2006 FIFA World Cup Germany with the various type of MMS(Multi Mode Service) using MPEG-2 encoding method. MMS Service can provides not only one HD channel but also serveral additional services within 6MHz bandwidth. Using digital video compression technology(MPEG-2), many various programs such as HDTV, SDTV, Audio and Data are able to be transmitted within the same bandwidth. From November 2009, KBS has been preparing an advanced MMS service, 'Korea-View' which has both methods of encoding, MPEG-2 and H.264 that is compliant ATSC mobile standard, A/153. Korea-View is a kind of multi-channel broadcast service to provide one HD and 3 SD programs with the bandwidth of 6MHz. Terrestrial multi-channel service is required to focuse on expanding viewer service. Such Terrestrial multi-channel services will contribute to transferring to digital broadcasting and to extending the viewers' welfare. Due to advances in digital technology, Pay-TV channels has increased to hundreds. Even though digital switchover is being proceeded, terrestrial broadcasters have been unable to deliver multi-channel services. In this paper, technical features and differences of MMS and Koreaview will be analyzed regarding terrestrial multi-channel broadcasting services, and the politic direction will be proposed in accordance with introduction of future service.