• Title/Summary/Keyword: volume index

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Comparison of plan dosimetry on multi-targeted lung radiotherapy: A phantom-based computational study using IMRT and VMAT

  • Khan, Muhammad Isa;Rehman, Jalil ur;Afzal, Muhammad;Chow, James C.L.
    • Nuclear Engineering and Technology
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    • v.54 no.10
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    • pp.3816-3823
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    • 2022
  • This work analyzed the dosimetric difference between the intensity modulated radiotherapy (IMRT), partial/single/double-arc volumetric modulated arc therapy (PA/SA/DA-VMAT) techniques in treatment planning for treating more than one target of lung cancer at different isocenters. IMRT and VMAT plans at different isocenters were created systematically using a Harold heterogeneous lung phantom. The conformity index (CI), homogeneity index (HI), gradient index (GI), dose-volume histogram and mean and maximum dose of the PTV were calculated and analyzed. Furthermore, the dose-volume histogram and mean and maximum doses of the OARs such as right lung, contralateral lung and non GTV were determined from the plans. The IMRT plans showed the superior target dose coverage, higher mean and maximum values than other VMAT techniques. PA-VMAT technique shows more lung sparing and DA-VMAT increases the V5/10/20 values of contralateral lung than other VMAT and IMRT techniques. The IMRT technique achieves highly conformal dose distribution to the target than other VMAT techniques. Comparing to the IMRT plans, the higher V5/10/20 and mean lung dose were observed in the contralateral lung in the DA-VMAT.

Dosimetric Comparison of Three Dimensional Conformal Radiation Radiotherapy and Helical Tomotherapy Partial Breast Cancer (유방암 환자의 3D-CRT, TOMO 방법에 따른 선량 분포 평가)

  • Kim, Dae-Woong;Kim, Jong-Won;Choi, Yun-Kyeong;Kim, Jung-Soo;Hwang, Jae-Woong;Jeong, Kyeong-Sik;Choi, Gye-Suk
    • The Journal of Korean Society for Radiation Therapy
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    • v.20 no.1
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    • pp.11-15
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    • 2008
  • Purpose: The goal of radiation treatment is to deliver a prescribed radiation dose to the target volume accurately while minimizing dose to normal tissues. In this paper, we comparing the dose distribution between three dimensional conformal radiation radiotherapy (3D-CRT) and helical tomotherapy (TOMO) plan for partial breast cancer. Materials and Methods: Twenty patients were included in the study, and plans for two techniques were developed for each patient (left breast:10 patients, right breast:10 patients). For each patient 3D-CRT planning was using pinnacle planning system, inverse plan was made using Tomotherapy Hi-Art system and using the same targets and optimization goals. We comparing the Homogeneity index (HI), Conformity index (CI) and sparing of the organs at risk for dose-volume histogram. Results: Whereas the HI, CI of TOMO was significantly better than the other, 3D-CRT was observed to have significantly poorer HI, CI. The percentage ipsilateral non-PTV breast volume that was delivered 50% of the prescribed dose was 3D-CRT (mean: 40.4%), TOMO (mean: 18.3%). The average ipsilateral lung volume percentage receiving 20% of the PD was 3D-CRT (mean: 4.8%), TOMO (mean: 14.2), concerning the average heart volume receiving 20% and 10% of the PD during treatment of left breast cancer 3D-CRT (mean: 1.6%, 3.0%), TOMO (mean: 9.7%, 26.3%) Conclusion: In summary, 3D-CRT and TOMO techniques were found to have acceptable PTV coverage in our study. However, in TOMO, high conformity to the PTV and effective breast tissue sparing was achieved at the expense of considerable dose exposure to the lung and heart.

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Evaluation of Dose Volume and Radiobiological Indices by the Dose Calculation Grid Size in Nasopharyngeal Cancer VMAT (비 인두암 체적 조절 호형 방사선 치료의 선량 계산 격자 크기에 따른 선량 체적 지수와 방사선 생물학적 지수의 평가)

  • Kang, Dong-Jin;Jung, Jae-Yong;Shin, Young-Joo;Min, Jung-Whan;Shim, Jae-Goo;Park, So-Hyun
    • Journal of radiological science and technology
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    • v.43 no.4
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    • pp.265-272
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    • 2020
  • The purpose of this study was to investigate the dose-volume indices and radiobiological indices according to the change in dose calculation grid size during the planning of nasopharyngeal cancer VMAT treatment. After performing the VMAT treatment plan using the 3.0 mm dose calculation grid size, dose calculation from 1.0 mm to 5.0 mm was performed repeatedly to obtain a dose volume histogram. The dose volume index and radiobiological index were evaluated using the obtained dose volume histogram. The smaller the dose calculation grid size, the smaller the mean dose for CTV and the larger the mean dose for PTV. For OAR of spinal cord, brain stem, lens and parotid gland, the mean dose did not show a significant difference according to the change in dose calculation grid size. The smaller the grid size, the higher the conformity of the dose distribution as the CI of the PTV increases. The CI and HI showed the best results at 3.0 mm. The smaller the dose calculation grid size, the higher the TCP of the PTV. The smaller the dose calculation grid size, the lower the NTCP of lens and parotid. As a result, when performing the nasopharynx cancer VMAT plan, it was found that the dose calculation grid size should be determined in consideration of dose volume index, radiobiological index, and dose calculation time. According to the results of various experiments, it was determined that it is desirable to apply a grid size of 2.0 - 3.0 mm.

The Analysis of the Oxidation Index of Korea Traditional Paper(Hanji) Which Is Used as the Rrestoration Paper of the Waxed Volume in the Annals of Joseon Dynasty (조선왕조실록 밀랍본 복원용지로서 전통한지의 oxidation index 분석)

  • Seo, Jin-Ho;Jeong, So-Young;Jeong, Seon-Hwa
    • Journal of Korea Technical Association of The Pulp and Paper Industry
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    • v.40 no.1
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    • pp.55-61
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    • 2008
  • The annals of Joseon Dynasty is the most valuable resource containing the record of Korean history and has been known as one of the UNESCO's Memory of the World Register. In some period, wax-treated paper was used in the annals of Joseon Dynasty to prevent the damage from pests. But, wax-treated volumes were discolored to brown, white or black, and partially cracked by the stiffened wax. It means that wax-treated volumes were damaged by the hardening and oxidizing of wax. The wax is considered as the first reason in damages on the wax-treated volume. Therefore, in this study we analysed the oxidation index of Korea traditional paper(Hanji) which is used as the restoration paper of the waxed volume in the annals of Joseon Dynasty by using FT-IR. As the analysis of FT-IR, the traditional two-layed stamping paper (Hanji sample F), which was treated by starch in its surface, was shown the most stable state after the accelerated ageing test.

A study on improving the evaluation of motorway functions using Trip Length Frequency Distribution(TLFD) (통행거리빈도분포를 활용한 고속도로 기능 평가 개선 연구)

  • Kwon, Ceholwoo;Yoon, Byoungjo
    • Journal of Urban Science
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    • v.11 no.2
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    • pp.9-17
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    • 2022
  • The purpose of this study is to develop an index for evaluating the function of a new motorway using the travel distance frequency distribution (TLFD) calculated using the vehicle travel route big data, and to overcome the limitations of the evaluation through the existing traffic volume. The mobility evaluation index of motorways was developed by applying it to the TLFD data table in 2019. The smaller the value of the mobility evaluation index of the link is calculated, the more it is a link with mainly short-distance travel, and the higher the value of the mobility evaluation index, the more it means a link with mainly long-distance travel. The accessibility evaluation index was calculated through the result of the mobility evaluation index of all motorways developed, and all motorways were grouped into three groups using K-means clustering. Group A was found to exist inside a large city and consisted of motorways with many short-distance traffic, Group B was investigated as acting as an arterial between groups, and Group C was classified as a motorway consisting mainly of long-distance traffic connecting large cities and large cities. This study is significant in developing a new motorway function evaluation index that can overcome the limitations of motorway function evaluation through the existing traffic volume. It is expected that this study can be a reasonable comprehensive indicator in the operation and planning process of motorways.

The Effect of Volume Reduction on Computed Treatment Planning during Head and Neck IMRT and VMAT (두경부 IMRT 및 VMAT 시 체적 감소가 전산화치료계획에 미치는 영향)

  • Ki-Cheon Um;Gha-Jung Kim;Geum-Mun Back
    • Journal of radiological science and technology
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    • v.46 no.3
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    • pp.239-246
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    • 2023
  • In this study, we assessed the effect of reduction of tumor volume in the head and neck cancer by using RANDO phantom in Static Intensity-Modulated Radiation Therapy (S-IMRT) and Volumetric-Modulated Arc Therapy (VMAT) planning. RANDO phantom's body and protruding volumes were delineated by using Contour menu of Eclipse™ (Varian Medical System, Inc., Version 15.6, USA) treatment planning system. Inner margins of 2 mm to 10 mm from protruding volumes of the reference were applied to generate the parameters of reduced volume. In addition, target volume and Organ at Risk (OAR) volumes were delineated. S-IMRT plan and VMAT plan were designed in reference. These plans were assigned in the reduced volumes and dose was calculated in reduced volumes using preset Monitor unit (MU). Dose Volume Histogram (DVH) was generated to evaluate treatment planning. Conformity Index (CI) and R2 in reference S-IMRT were 0.983 and 0.015, respectively. There was no significant relationship between CI and the reduced volume. Homogeneity Index (HI) and R2 were 0.092 and 0.960, respectively. The HI increased when volume reduced. In reference VMAT, CI and R2 were 0.992 and 0.259, respectively. There was no relationship between the volume reduction and CI. On the other hand, HI and R2 were 0.078 and 0.895, respectively. The value of HI increased when the volume reduced. There was significant difference (p<0.05) between parameters (Dmean and Dmax) of normal organs of S-IMRT and VMAT except brain stem. Volume reduction affected the CI, HI and OAR dose. In the future, additional studies are necessary to incorporate the reduction of the volume in the clinical setting.

Effect of power law index for vibration of armchair and zigzag single walled carbon nanotubes

  • Khadimallah, Mohamed Amine;Hussain, Muzamal
    • Steel and Composite Structures
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    • v.37 no.5
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    • pp.621-632
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    • 2020
  • This research deals with the study of vibrational behavior of armchair and zigzag single-walled carbon nanotubes invoking extended Love shell theory. The effects of different physical and material parameters on the fundamental frequencies are investigated. By using volume fraction for power law index, the fundamental natural frequency spectra for two forms of single-walled carbon nanotubes are calculated. The influence of frequencies against length-to-diameter ratios with varying power law index are investigated in detail for these tubes. To discretize the governing equation in eigen-value form, wave propagation approach is developed. Complex exponential functions have been used and the axial model depends on boundary condition that has been described at the edges of carbon nanotubes to calculate the axial modal dependence. Computer software MATLAB is utilized for the frequencies of single-walled carbon nanotubes and current results shows a good stability with comparison of other studies.

Analysis of cross-talk effects in volume holographic interconnections using perturbative integral expansion method

  • Jin, Sang-Kyu
    • Journal of the Optical Society of Korea
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    • v.2 no.2
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    • pp.58-63
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    • 1998
  • Cross-talk effects in high-density volume holographic interconnections are investigated using perturbative iteration method of the integral form of Maxwell's wave equation. In this method, the paraxial approximation and negligence of backward scattering introduced in conventional coupled mode theory is not assumed. Interaction geometries consisting of non-coplanar light waves and multiple index gratings are studied. Arbitrary light polarization is considered. Systematic analysis of cross-talk effects due to multiple index gratings is performed in increasing level of diffraction orders corresponding to successive iterations. Some numerical examples are given for first and third order diffraction.

A Study of Intracranial Hemodynamic Change with Aging (노화에 따른 두개내 혈류의 혈류 동력학적 변화에 관한 연구)

  • Kim Jong-Soon;Kim Byung-Jo;Bae Sung-Soo
    • The Journal of Korean Physical Therapy
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    • v.14 no.4
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    • pp.119-130
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    • 2002
  • The purpose of this study was to evaluate hemodynamics of intracranial blood flow for obtain clinically useful reference values and assess cerebral hemodynamics change with aging. 81 normal Korean subjects(age, 14$\thicksim\∼\thicksim$70 years) examined who han no history of neurologic disease and the subjects divided into group A(age, 14$\∼$39 years), group B(age, 40$\∼$59 years) and group C(age, 60$\∼$70 years). Transcranial doppler was use for measured the maximum velocity(Vmax), mean velocity(Vmean), pulsatility index(PI), resistive index(RI), stenosis index(SI) and depth of sample volume. Vmax was 99.1 1cm/s, Vmean was 63.57cm/s, PI was 0.85, RI was 0.56, SI was 31.94 and depth of sample volume was 52.35 in middle cerebral artery. Vmax was 85.54cm/s, Vmean was 52.52cm/s, PI was 0.82, RI was 0.55, SI was 34.48 and depth of sample volume was 73.62 in anterior cerebral artery. Vmax was 75.45cm/s, Vmean was 45.60cm/s, PI was 0.82, RI was 0.58, SI was 36.14 and depth of sample volume was 62.35 in posterior cerebral artery. Vmax was 70.44cm/s, Vmean was 47.07cm/s, PI was 0.87, RI was 0.58, SI was 29.83 and depth of sample volume was 75.23 in basilar artery Vmax was 63.92, Vmean was 42.42, PI was 0.89, RI was 0.58, SI was 29.89 and depth of sample volume was 66.65 in vertebral artery. Vmax and Vmean was significantly decreased with increasing age in middle cerebral artery, anterior cerebral artery, posterior cerebral artery, basilar artery and vertebral artery And PI and RI was significantly increased with increasing age in basilar artery and vertebral artery. And I suggest that transcranial doppler sonography can be used as one of useful clinical tool for detection of cerebral hemodynamics.

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The study on the characteristics of the price discovery role in the KOSPI 200 index futures (주가지수선물의 가격발견기능에 관한 특성 고찰)

  • 김규태
    • Journal of the Korea Society of Computer and Information
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    • v.7 no.2
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    • pp.196-204
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    • 2002
  • This paper examines the price discovery role of the KOSPI 200 futures index for its cash index. It was used the intrady data for KOSPI 200 and futures index from July 1998 to June 2001. The existing Preceding study for KOSPI 200 futures index was used the data of early market installation, but this study is distinguished to use a recent data accompanied with the great volume of transaction and various investors. We established three hypothesis to examine whether there is the price discovery role in the KOPSI 200 futures index and the characteristics of that. First, to examine whether the lead-lag relation is induced by the infrequent trading of component stocks, observations are sorted by the size of the trading volume of cash index. In a low trading volume, the long lead time is reported and the short lead time in a high volume. It is explained that the infrequent trading effect have an influence on the price discovery role. Second, to examine whether the lead-lag relation is different under bad news and good news, observations are sorted by the sign and size of cash index returns. In a bad news the long lead time is reported and the short lead time in a good news. This is explained by the restriction of"short selling" of the cash index Third, we compared estimates of the lead and lag relationships on the expiration day with those on days prior to expiration using a minute-to-minute data. The futures-to-spot lead time on the expiration day was at least as long as other days Prior to expiration, suggesting that "expiration day effects" did not demonstrate a temporal character substantially different form earlier days. Thus, while arbitrage activity may be presumed to be the greatest at expiration, such arbitrage transactions were not sufficiently strong or Pervasive to alter the empirical price relationship for the entire day. for the entire day.

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