• Biotechnology and Bioprocess Engineering:BBE
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• v.11 no.1
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• pp.43-47
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• 2006

Ginseng (Panax ginseng CA. Meyer) hairy root cultures, which are established via the infection of ginseng root discs with Rhizobium rhizogenes, have been used to construct profiles of both biomass growth and nutrient consumption in flask cultures. In a 250 mL shake flask culture, the maximum biomass was observed on the 59th day of the culture period, at 216.8 g (fresh wt) per liter or 11.4 g (dry wt) per liter. The hairy roots were determined to have a growth rate of 0.355 g-DW/g cells/day during the exponential growth phase and a maximum specific growth rate on day 7. Total ginseng saponin and phenolic compound contents were noted to have increased within the latter portion of the culture period. Linear correlations between increases in biomass weight and nutrient uptake were used to imply the conductivity yield $2.60g-DW/(L{\cdot}mS)$ and carbon yield 0.45 g-DW/(g sugar) in the 250 mL flask cultures. The biomass yield when two different nitrogen sources were used (ammonia and nitrate) was shown to remain approximately constant. at $0.47g-DW/(L{\cdot}mM\;NH_4$) and $0.33g-DW/(L{\cdot}mM\;NO_3$); it remained at these levels for 16 days with the ammonia. and for 24 days with the nitrate. The biomass yield when a phosphate source was used was also shown to remain approximately constant for 9 days, at $3.17g-DW/(L{\cdot}mM\;PO_4$), with an $R^2$ of 0.99.

• Membrane Journal
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• v.13 no.1
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• pp.37-46
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• 2003

The electrokinetic effect can be found in cases of the fluid flowing across the charged membrane micropores. The externally applied body force originated from the electrostatic interaction between the nonlinear Poisson-Boltzmann field and the flow-induced electrical field is taken into the equation of motion. The electrostatic potential profile is computed a priori by applying the finite difference scheme, and an analytical solution to the Navier-Stokes equation of motion for slit-like pore is obtained via the Green's function. An explicit analytical expression for the flow-induced streaming potential is derived as functions of relevant physicochemical parameters. The influences of the electric double layer, the surface potential of the wall, and the charge condition of the pore wall upon the velocity profile as well as the streaming potential are examined. With increasing of either the electric double layer thickness or the surface potential, the average fluid velocity is entirely reduced, while the streaming potential increases.

• Journal of Dental Rehabilitation and Applied Science
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• v.31 no.3
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• pp.262-272
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• 2015

Loss of molar support and abnormal jaw relationship lead to occlusal disharmony and cause pathologic signs. Full mouth rehabilitations with reestablishment of occlusal schemes are needed. In this case, the 75 year-old female patient showed posterior bite collapse, irregular occlusal plane and Class II jaw relationship. By observing her profile and interocclusal distance, she was diagnosed as loss of occlusal vertical dimension. Treatment plan is to restore maxillay class I removable partial denture and mandibular fixed prosthesis and to establish vertical dimension and harmonious occlusal plane. Occlusal vertical dimension of 19 mm, which is obtained by 7.5 mm increase between maxillary right lateral incisor and mandibular canine, was established using temporary prosthesis via diagnostic wax-up. Patient adaptation with newly formed vertical dimension was verified during 8 week follow-up period. Within the information of interim prostheses, final restoration was constructed and delivered. The patient showed sound occlusal scheme and esthetic profile.

• Maxillofacial Plastic and Reconstructive Surgery
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• v.13 no.1
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• pp.37-43
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• 1991

Cephalometric prediction tracing is the preoperative double checking procedure which can predict bony and soft tissue change. Soft tissue profile prediction is routinely performed according to the known ratios of the soft to hard tissue movement which can vary considerably in each individual. Besides interindividual variation of the ratios of the soft to hard tissue change, actual results of the postoperative soft tissue profile can reflect other important modifying factors if it is compared with prediction tracing used. The purpose of this study is to compare soft tissue prediction tracing used with postoperative tracing and to find intervening modifying factor via serial tracing. Review of 30 prediction tracing showed that the most important factor contributing to prodiction tracing inaccuracy was the skeletal and dental relapse. And, some factors which may be responsible for prediction tracing inaccuracy were discussed.

• Wind and Structures
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• v.14 no.4
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• pp.285-300
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• 2011

Researchers at the International Hurricane Research Center (IHRC), Florida International University (FIU), are working in stages on the construction of a large state-of-the-art Wall of Wind (WoW) facility to support research in the area of Wind Engineering. In this paper, the challenges of simulating hurricane winds for the WoW are presented and investigated based on a scale model study. Three wind profiles were simulated using airfoils, and/or adjustable planks mechanism with and without grids. Evaluations of flow characteristics were performed in order to enhance the WoW's flow simulation capabilities. Characteristics of the simulated wind fields are compared to the results obtained from a study using computational fluid dynamics (CFD) and also validated via pressure measurements on small-scale models of the Silsoe cube building. Optimal scale of the test model and its optimal distance from the WoW contraction exit are determined - which are two important aspects for testing using an open jet facility such as the WoW. The main objective of this study is to further the understanding of the WoW capabilities and the characteristics of its test section by means of intensive tests and validations at small scale in order to apply this knowledge to the design of the full-scale WoW and for future wind engineering testing.

• Korean Journal of Microbiology
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• v.38 no.3
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• pp.213-220
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• 2002

Inducible expression system for the three structural proteins, capsid (C), precursor membrane (prM/M), and envelop (E) of Japanese encephalitis virus (JEV) was established in BHK-21 cells. Doxycycline, a tetracycline analog, was utilized as an inducer. Transfectants BHK-21/IV (vector only), BHK-21/IC (for C), BHK-21/IP3 (for prM), and BHK-21/IE1 (for E) were selected and cloned in the presence of G4l8 or hygromycin. Transcribed mRNAs for the corresponding genes were observed after doxycycline induction. Effects by the JEV structural gene expression on the transfectants were monitored via cell growth, chromatin condensation, internucleosomal DNA fragmentation, and DNA contents analyses. Clear cell growth retardation and chromatin condensation were observed in all three transfectants while only BHK-2/IC corresponded to the induction status in the DNA fragmentation and DNA content analyses. Combined results, therefore, suggested that JEV capsid protein should be one of the direct and independent factors in apoptotic cell death induced by IEV infection.

• Journal of the Korean Society for Nondestructive Testing
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• v.24 no.1
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• pp.1-7
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• 2004

The angular dependence (or profile) of backscattered ultrasound was measured for steel specimens with a range of surface roughness, $1{\sim}71{\mu}m$. Backscattering profiles at or near the Rayleigh angle still showed roughness dependence while the assessment of surface roughness via normal profile became impossible due to the paint layer masking the roughness. The peak amplitude directly radiated at the Rayleigh angle was proportional to the surface roughness, while the averaged peak amplitude radiated from the backward propagating Rayleigh wave, produced by reflection at a corner, was inversely proportional. In the painted specimens, the linearity of direct backward radiation with the roughness was observed even at the roughness of less than three hundredths of a wavelength, and the abnormal multiple bark reflection caused by periodic roughness disappeared.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.25 no.5
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• pp.691-700
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• 2021

The IP cameras have rapidly replaced the analog CCTVs as the cameras have the advantages of not only being able to remotely monitor, but also supplying power through the UTP cable, In this paper, we introduce the protocol architecture of the ONVIF standard which is widely applied to the IP camera and other Internet protocols to support it, and implement the ONVIF Device on a commercial board. Although these functions can be controlled by the Client (PC), several functions such as privacy masks, temperature display of the thermal camera, and ROI (Region of Interest) are implemented through a web viewer on the device. Through the experiment, the functions of ONVIF Profile S and web viewer are verified through SOAP messages exchanged between Device (IP camera) and Client program and streamed images.

• Phonetics and Speech Sciences
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• v.13 no.4
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• pp.67-74
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• 2021

This study examines the effectiveness of semi-occluded vocal tract exercise (SOVTE) conducted through telepractice for 10 female teachers who have experienced vocal discomfort while working in early childhood education facilities (childcare centers, kindergartens). The effects of SOVTE conducted through telepractice were evaluated based on the Korean voice handicap index (KVHI), the Korean version of the voice activity and participation profile (K-VAPP), vocal effort, and auditory perception evaluation by using the grade, roughness, breathiness, asthenia, and strain (GRBAS) scale. The results show that total, functional, and physical scores of KVHI significantly reduced after SOVTE. The total score in K-VAPP significantly reduced after SOVTE. Moreover, vocal effort significantly decreased after SOVTE. However, statistically significant differences were not noted in GRB scales before and after SOVTE. In conclusion, early childhood teachers experienced reduced vocal discomfort SOVTE conducted through telepractice. The study results indicate that voice therapy conducted through telepractice is an effective method for reducing vocal discomfort in early childhood teachers.

• Journal of Veterinary Science
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• v.23 no.5
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• pp.64.1-64.9
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• 2022

Background: Fluralaner is a novel drug belonging to the isoxazoline class that acts on external parasites of domestic animals. It is used systemically via drinking water, especially against red poultry mite in layer chickens. Fluralaner is frequently used in layers infected with D. gallinae. However, no study to date has investigated the effects of feed intake and water hardness. Objectives: This study aimed to investigate the effects of variable water hardness and feed intake on the pharmacokinetic profile of fluralaner. Methods: Layer chickens were divided into four groups (n = 8): fed + purified water (Group 1), feed restricted + purified water (Group 2), feed restricted + hard water (Group 3), and feed restricted + soft water (Group 4). After administering a single dose of the drug with drinking water, the blood samples were collected for 21 days. Fluralaner concentrations in plasma samples were determined by liquid chromatography/tandem mass spectrometry. The maximum plasma concentration (C_max), time to reach maximum plasma concentration (t_max), area under the concentration-time curve values (AUC_0-21d), half-life (t_1/2), and other pharmacokinetic parameters were calculated. Results: Although the highest maximum plasma concentration (C_max) was determined in Group 1 (fed + purified water), no statistically significant difference was found in the C_max, t_max, t_1/2, MRT_{0-inf_obs}, Vz/F_obs, and Cl/F_{_obs} parameters between the experimental groups. Conclusions: It was concluded that the feed intake or water hardness did not change the pharmacokinetic profile of fluralaner in layer chickens. Therefore, fluralaner could be used before or after feeding with the varying water hardness in poultry industry.