• Fisheries and Aquatic Sciences
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• v.16 no.4
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• pp.303-309
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• 2013

Microsatellite markers are important for gene mapping and for marker-assisted selection. Sixty-five polymorphic microsatellite markers were developed with an enriched partial genomic library from olive flounder Paralichthys olivaceus an important commercial fish species in Korea. The variability of these markers was tested in 30 individuals collected from the East Sea (Korea). The number of alleles for each locus ranged from 2 to 33 (mean, 17.1). Observed and expected heterozygosity as well as polymorphism information content varied from 0.313 to 1.000 (mean, 0.788), from 0.323 to 0.977 (mean, 0.820), and from 0.277 to 0.960 (mean, 0.787), respectively. Nine loci showed significant deviation from the Hardy-Weinberg equilibrium after sequential Bonferroni correction. Analysis with MICROCHECKER suggested the presence of null alleles at five of these loci with estimated null allele frequencies of 0.126-0.285. These new microsatellite markers from genomic libraries will be useful for constructing a P. olivaceus linkage map.

• Journal of The Korean Society of Integrative Medicine
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• v.4 no.4
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• pp.77-82
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• 2016

Purpose: The purpose of this study was to investigate the therapeutic effect of non-invasive vagus nerve stimulation by transcutaneous electrical nerve stimulation application on the autonomic nervous system of human body. Methods: Participants were seventeen healthy adults. Standard deviation of all normal N-N intervals(SDNN), root mean square of successive differences(RMSSD), low frequency(LF), high frequency(HF) were compared in pre and post Mean values after intervention. Data were analyzed in Wilcoxon's signed-ranks test. Results: The results of this study is that sistolic blood pressure and pulse rate decreased mean value after non-invasive vagus nerve stimulation by transcutaneous electrical nerve stimulation. High frequency, low frequency, SDNN, RMSSD increased mean value in heart rate variability after intervention. But that is not significant except for SDNN. Conclusion: Non-invasive vagus stimulation by transcutaneous electrical nerve stimulation effect on parasympathetic nerve stimulation, and then it might be effective method for autonomic nerve balance control.

• Journal of Korean Society for Quality Management
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• v.46 no.1
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• pp.39-74
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• 2018

Purpose: For more than 30 years, robust parameter design (RPD), which attempts to minimize the process bias (i.e., deviation between the mean and the target) and its variability simultaneously, has received consistent attention from researchers in academia and industry. Based on Taguchi's philosophy, a number of RPD methodologies have been developed to improve the quality of products and processes. The primary purpose of this paper is to review and discuss existing RPD methodologies in terms of the three sequential RPD procedures of experimental design, parameter estimation, and optimization. Methods: This literature study composes three review aspects including experimental design, estimation modeling, and optimization methods. Results: To analyze the benefits and weaknesses of conventional RPD methods and investigate the requirements of future research, we first analyze a variety of experimental formats associated with input control and noise factors, output responses and replication, and estimation approaches. Secondly, existing estimation methods are categorized according to their implementation of least-squares, maximum likelihood estimation, generalized linear models, Bayesian techniques, or the response surface methodology. Thirdly, optimization models for single and multiple responses problems are analyzed within their historical and functional framework. Conclusion: This study identifies the current RPD foundations and unresolved problems, including ample discussion of further directions of study.

• Proceedings of the Korea Water Resources Association Conference
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• 2004.05b
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• pp.479-483
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• 2004

A new calculation method of expected overtopping probability of rubble mound breakwater considering real tide occurrence has been proposed. A calculation method of expected overtopping probability of rubble mound breakwater was proposed by Kweon and Suh (2003). In their calculation, the fluctuation of tidal elevation was expressed by the sinusoidal change that yields the uniform distribution of occurrence frequency. However, the realistic distribution of tidal elevation should influence on the overtopping chance. In this study, the occurrence frequency of tidal elevation obtained from the real sea is included. The tidal elevation used in this study is collected from the east coastal part of Korean peninsular. Analyzing the annual data of the tidal fluctuation measured hourly during 355 days, the distribution of occurrence frequency is formulated utilizing by the normal distribution with one peak. Among the calculation procedures of annual maximum wave height, wave height-period joint distribution, wave run-up height and occurrence frequency of tide, only the annual maximum wave height is again chosen randomly from normal distribution to consider the uncertainty. The others are treated by utilizing the distribution function or relationship itself, It is found that the inclusion of the variability of tidal elevation has great influence on the computation of the expected overtopping probability of rubble mound breakwater. The bigger standard deviation of occurrence frequency is, the lower the overtopping probability of rubble mound breakwater is.

• Journal of Korea Water Resources Association
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• v.43 no.11
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• pp.933-944
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• 2010

This study compares the CEM and SGS methods which are geostatistical stochastic simulation methods for assessing the uncertainty by spatial variability in the estimation of the spatial distribution of probability rainfall. In the stochastic simulations using CEM and SGS, two methods show almost similar results for the reproduction of spatial correlation structure, the statistics (standard deviation, coefficient of variation, interquartile range, and range) of realizations as uncertainty measures, and the uncertainty distribution of basin mean rainfall. However, the CEM is superior to SGS in aspect of simulation efficiency.

• Smart Structures and Systems
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• v.22 no.4
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• pp.441-457
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• 2018

Characteristic parameter values of seismic isolators deviate from their nominal design values due to uncertainties and/or errors in their material properties and element dimensions, etc. Deviations may increase over service life due to environmental effects and service conditions. For accurate evaluation of the seismic safety level, all such effects, which would result in deviations in the structural response, need to be taken into account. In this study, the sensitivity of the probability of failure of the structures equipped with nonlinear base isolation systems to the uncertainties in various isolation system characteristic parameters is investigated in terms of various isolation system and superstructure response parameters in the context of a realistic three-dimensional base-isolated building model via Monte Carlo Simulations. The inherent record-to-record variability nature of the earthquake ground motions is also taken into account by carrying out analyses for a large number of ground motion records which are classified as those with and without forward-directivity effects. Two levels of nominal isolation periods each with three different levels of uncertainty are considered. Comparative plots of cumulative distribution functions and related statistical evaluation presented here portray the potential extent of the deviation of the structural response parameters resulting from the uncertainties and the uncertainty levels considered, which is expected to be useful for practicing engineers in evaluating isolator test results for their projects.

• Journal of Environmental Science International
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• v.2 no.1
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• pp.27-42
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• 1993

Based on the Results of Marine Meteorological and Oceanographical Observations during 1966∼1987 and the Ten-day Marine Report during 1970∼1989 by Japan Meteorological Agency, the possible area where the Japan Sea Proper Water (JSPW) can be formed is investigated by analyzing the distribution of water types in the Japan Sea. The Japan Sea can be divided into three subareas of Northern Cold Water(NCW), Polar Front(PF) and Tsushima Warm Current (TWC) by the Polar Front identified by a 6℃ isothermal line at the sea surface in vinter. Mean position of the Polar Front is approximately parallel to the latitude 39∼40。N. The standard deviation of the Polar Front from the mean position of about 130km width is the smallest in the region between 136。E and 138。E where the Polar Front is very stable, because the branches of the Tsushima Current are converging in this region. However, standard deviations are about 180∼250km near the Korean peninsula and the Tsugaru Strait due to greater variability of warm currents. In the NCW area north of 40∼30。N and west of 138。E, the water types of the sea surface to the loom depth are similar to those of the JSPW. This fact indicates that the surface layer of the NCW area is the possible region of the JSPW formation in winter.

• Journal of The Korean Society of Agricultural Engineers
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• v.54 no.5
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• pp.123-128
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• 2012

For optimal reservoir operation and management, there are essential elements including water supply in agricultural reservoir and demand in irrigation district. To estimate agricultural water demand and supply, many factors such as weather, crops, soil, growing conditions cultivation method and the watershed/irrigation area should be considered, however, there are occurred water supply impossible duration under the influence of the variability and uncertainty of meteorological and hydrological phenomenon. Focusing on agricultural reservoir, amount and tendency of agricultural water supply and demand shows seasonally/regionally different patterns. Through the analysis of deviation and changes in the timing of the two elements, duration in excess of water supply can be identified quantitatively. Here, we introduce an approach to assessment of irrigation vulnerable duration for effective management of agricultural reservoir using time dependent change analysis of residual water supply and irrigation water requirements. Irrigation vulnerable duration has been determined through the comparison of water supply in agricultural reservoir and demand in irrigation district based on the water budget analysis, therefore can be used as an improved and basis data for the effective and intensive water management.

• The Journal of Internal Korean Medicine
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• v.45 no.3
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• pp.478-487
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• 2024

Objectives: This case report describes good clinical progress in a patient with symptoms related to angina pectoris treated with a herbal medication. Methods: The 66-year-old male patient hospitalized in Chonnam National University Hospital (CNUH) in May 2020 for symptoms of dyspnea and chest pain was diagnosed with angina pectoris, medicated, underwent PCI in August 2020, and continued to take the medicine prescribed at CNUH during hospitalization. Korean medical treatments, including herbal medicines (Saengmaeg-san-hap-Bojungikgi-tang-gami, Yeonggyechulgam-tang), acupuncture, and cupping therapy were administered for 22 days. Symptom severity was assessed with a daily visual analog scale (VAS) for dyspnea and chest pain and standard deviation of NN (SDNN) score of heart rate variability. Results: Post-treatment, severity of dyspnea, chest pain, and fatigue reduced from VAS 7 to VAS 2, VAS 6 to VAS 1, and VAS 7 to VAS 1, respectively. The SDNN score improved from 16.474 ms to 23.270 ms. There were no side effects from Korean medicine treatment. Conclusion: Traditional Korean treatment could effectively treat symptoms related to angina pectoris.

• Journal of the Korean Applied Science and Technology
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• v.41 no.2
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• pp.219-232
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• 2024

The aim of this study was to explore the impact of body mass index (BMI) and drumming exercise on autonomic nervous system function in adult women. Ten adult women (aged 30-50) were divided into two groups based on their BMI: a normal BMI group (Low BMI, LBMI < 23 kg/m²) and an overweight BMI group (High BMI, HBMI > 23 kg/m²). Both groups participated in a drumming exercise program, consisting of 50-minute sessions, three times a week, for a duration of 8 weeks. Body composition and heart rate variability were assessed before and after the 8-week exercise period. Heart rate variability was evaluated using linear analysis in the time domain and frequency domain. Additionally, non-linear analysis was conducted using a Poincaré plot. The autonomic nervous system index was determined by measuring parasympathetic nervous system index and sympathetic nervous system index. Following the 8-week intervention, the HBMI group exhibited a significant decrease in weight (p=0.034), BMI (p=0.044), body fat mass (p=0.032), and waist circumference (p=0.013) compared to the LBMI group. Furthermore, the HBMI group demonstrated significant increases in RMSSD (p=0.018) and TP (p=0.033) in linear analysis, as well as SD1 (p=0.018) in non-linear analysis and PNS Index (p=0.040) compared to the LBMI group. RMSSD, SD1, and PNS Index serve as indicators of parasympathetic nervous system activity in linear and non-linear analyses, respectively. These findings indicate that drumming exercise significantly enhances autonomic nervous system function in overweight women.