• 제목/요약/키워드: vFo

검색결과 128건 처리시간 0.02초

편측성대마비에 대한 제 1형 갑상성형술과 피열연골내전술의 동시수술시 술전 및 술후 음성언어분석비교 (Analysis of Pre and Post-Operative Speech In Combined Operation of Type I Thyroplasty and Arytenoid Adduction for Unilateral Vocal Cord Palsy)

  • 최홍식;정유삼;김성국;김영호;김광문
    • 대한후두음성언어의학회지
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    • 제9권1호
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    • pp.66-70
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    • 1998
  • Background and Objectives : The managements of unilateral vocal cord palsy include type Ⅰ thyroplasty and arytenoid adduction. One type operation has been shown no satisfactory effect. We evaluated preoperative and postoperative speech of unilateral vocal cord palsy patients who received combined operation of type Ⅰ thyroplasty and arytenoid adduction to help for the management plan of unilateral vocal cord palsy patients. Materials and Methods : We reviewed the postoperative results and complication of 17 surgically treated patients of unilateral vocal cord palsy at Severance hospital from Nov. 1996 to Dec. 1997 retrospectively. They were received combined operation of type Ⅰ thyroplasty and arytenoid adduction. Their pre and post-operative speech were analyzed with MDVP(Multi-Dimension-Voice analysis Program) of CSL(Computerized Speech Lab). Results : After the operation, MPT(Maximal Phonation Time) was increased and MFR(Mean Flow Rate) was decreased in all patients. NHR(Noise to Harmonic Ratio) and VTI(Voice Turbulence Index) were decreased : liner, RAP(Relative Average Perturbation Quotient), PPQ(Pitch Period Perturbation Quotient), sPPQ(smoothed Pitch Period Perturbation Quotient), vFo(fundamental frequency Variation) were decreased : Shimmer, APQ(Amplitude Perturbation Quotient), sAPQ(Smoothed Amplitude Perturbation Qoutient), vAm(Peak Amplitude Variation) were decreased in all the patients. Conclusions : In unilateral vocal cord pals), combined operation of type Ⅰ thyroplasty and arytenoid adduction could obtain satisfactory postoperative voice. MDVP has many parameters and good method for evaluation of voice surgery.

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생쥐 착상 전 배아에서 용해된 Matrigel에 의한 Mitogen Activated Protein Kinase 활성의 조절 (Regulation of Mitogen Activated Protein Kinase Activity by Solubilized Matrigel in the Preimplantation Mouse Embryos)

  • 강병문;정병목;계명찬
    • 한국발생생물학회지:발생과생식
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    • 제6권1호
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    • pp.1-6
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    • 2002
  • 세포외기질(exrtracellular matrix, ECM)에 의한 생쥐 초기 배아의 발생 조절 현상의 기작 규명을 위한 연구의 일환으로 Engelbreth-Holm-Swarm(EHS) mouse sarcoma의 세포외기질로부터 추출한 ECM 복합체인 Matrigel의 성장인자 제거형(GFR-Matrigel)을 생쥐 포배에 처리한 후 mitogen activated protein kinase (MAPK, ERK1/2) 활성 의 변화를 조사하였다. Matrigel 처리 후 10분 이내에 배아의 MAPK 활성이 유의하게 증가하였고, 60분 후에도 유의하게 높은 활성을 유지하였다. 한편 MAPK cascade의 저해제인 PD098059를 전처리한 경우 Matrigel에 의한 MAPK 활성의 증가가 관찰되지 않았다. Matrigel 배양액 내에서 12시간 동안 배양한 포배의 MAPK 활성은 대조군과는 현격한 차이를 보였다. 이러한 결과로부터 ECM에 의한 생쥐초기 배아의 발생 촉진효과 발현기작에는 하위 신호전달 과정의 MAPK 활성화 과정이 관여하는 것으로 사료된다.

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P-toluenesulfonanilide, $C_{13}H_{13}NO_2S$의 결정 및 분자구조 (The Crystal and Molecular Structure of P-toluenesulfonanilide, $C_{13}H_{13}NO_2S$)

  • 박권일;조성일
    • 한국결정학회지
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    • 제6권1호
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    • pp.43-48
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    • 1995
  • X-ray 회절법을 이용하여 P-toluenesulfonanilide, C13H13NO2S의 결정 및 분자구조를 규명하였다. Methanol 용액으로부터 얻은 무색 단결정은 단사정계, 공간군은 P21/c이며, a=8.777(1)Å, b=9.784(2)Å, c=15.139(2)Å, β=99.00(1)°, Z=4, V=1284.0(6)Å3, Dc=1.28g/cm3, λ(Mo-Kα)=0.71069Å, μ=2.3cm-1, F(000)=520, Temperature : 293±3K, 직접법으로 개략적인 분자모델을 설정하고 3.0σ이상인 711개의 독립 회절반점에 대하여 완전행렬 최소자승법으로 정밀화하여 최종신뢰도값 R=0.038인 최종적인 분자모형을 구하였다. 두 벤젠고리의 이면각이 68.4°이며 분자들은 c축 방향 2회선 나선형으로 이상적으로 충진되어 있으며 분자간은 van der Walls 결합력으로 이루어져있다.

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비교기 기반 입력 전압범위 감지 회로를 이용한 6비트 500MS/s CMOS A/D 변환기 설계 (Design of a 6-bit 500MS/s CMOS A/D Converter with Comparator-Based Input Voltage Range Detection Circuit)

  • 시대;이상민;윤광섭
    • 한국통신학회논문지
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    • 제38A권4호
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    • pp.303-309
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    • 2013
  • 입력 전압 범위 감지 회로를 이용해서 저전력 6비트 플래시 500Ms/s ADC를 설계하였다. 입력 전압 범위 감지 회로는 변환기내 모든 비교기들 중에서 25%만 동작시키고, 나머지 75%는 동작시키지 않는 방법을 채택하므로 저전력 동작을 가능하게 설계 및 제작하였다. 설계된 회로는 0.13um CMOS 공정기술을 이용해서 제작하였고, 1.2V 전원전압에서 68.8mW 전력소모, 4.9 유효 비트수, 4.75pJ/step의 평가지수가 측정되었다.

The a-Si:H/poly-Si Heterojunction Solar Cells

  • Kim, Sang-Su;Kim, do-Young;Lim, Dong-Gun;Junsin Yi;Lee, Jae-Choon;Lim, Koeng-Su
    • Journal of Electrical Engineering and information Science
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    • 제2권5호
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    • pp.65-71
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    • 1997
  • We present heterojunction solar cells with a structure of metal/a-Si:H(n-i-p)/poly-Si(n-p)/metal for the terrestrial applications. This cell consists fo two component cells: a top n-i-p junction a-Si:Hi cell with wide-bandgap 1.8eV and a bottom n-p junction poly-Si cell with narrow-bandgap 1.1eV. The efficiency influencing factors of the solar cell were investigated in terms of simulation an experiment. Three main topics of the investigated study were the bottom cell with n-p junction poly-Si, the top a-Si:H cell with n-i-p junction, and the interface layer effects of heterojunction cell. The efficiency of bottom cell was improved with a pretreatment temperature of 900$^{\circ}C$, surface polishing, emitter thickness of 0.43$\mu\textrm{m}$, top Yb metal, and grid finger shading of 7% coverage. The process optimized cell showed a conversion efficiency about 16%. Top cell was grown by suing a photo-CVD system which gave an ion damage free and good p/i-a-Si:H layer interface. The heterojunction interface effect was examined with three different surface states; a chemical passivation, thermal oxide passivation, and Yb metal. the oxide passivated cell exhibited the higher photocurrent generation and better spectral response.

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생강추출물의 열처리에 따른 항산화성 변화 (Changes of antioxidative properties according to the heat-treatment of ginger extracts)

  • 이진영;안명수
    • 한국식품조리과학회지
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    • 제10권1호
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    • pp.63-70
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    • 1994
  • Oleoresin, 6-gingerol and 6,10-gingerol: 6-paradol= 1 : 1 mixture were extracted from ginger (Zingi-her of ficinale Roscoe) and changes of its antioxidant activity by heat-treatment were studed. Oleoresin was extracted with Ethanol-Ether and 6,10-gingerol : 6-paradol(1 : 1) and 6-gingerol were extracted with Hexane and Hexan : Ether= 1 : 1, respectively, and identified on the Thin-layer Chromatograpy (TLC) plate with the solvent system of Hexane Ether(1 : 4, v/v). And oleoresin was heat-treated during 0, 10, 30, 60, 120 minutes, and 6-gingercl and 6,10-gingerol . 6-paradol=1 : 1 were heat-treated during 0, 5, 10, 20, 40 minutes, respectively, at 140$^{\circ}C$ dry oven. To compare with antioxidant activity, oleoresins were added into soybean oil at 3fo level, 6-gingerol and 6,10-gingerol : 6-paradol= 1 : 1 at 0.1% level, BHT and TBHQ at 0.02% level, respectively. All the substrates treated were stored in a incubator at 45 2$^{\circ}C$ condition. The oxidative stability was estimated by the analysises of peroxide value and conjugated diene value during storage. The results were as follows: Antioxidant activity of oleoresins were considerably high and by heat-treatment were not decreased. 6-paradol was not show the antioxidant activity. 6,10-gingerol : 6-paradol=1 : 1 provided poor protection for soybean oil. Antioxidant activity of 6-gingerol was higher than 6,10-gingerol : 6-paradol=1 : 1 and by heat-treat-ment antioxidant activity was directly decreased. Relative antioxidant effectiveness(RAE) of each antio-xidant was compared. RhR was found to decrease as follow : TBHQ>oleoresin》BHT TBHQ》BHT>6-gingerol》6,10-gingerol : 6-paradol=1 : 1.

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양성성대질환의 웃음 음성치료(SKMVTT) (Efficacy of laughing voice treatment (SKMVTT) in benign vocal fold lesions)

  • 정대용;위준열;김성태
    • 말소리와 음성과학
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    • 제10권4호
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    • pp.155-161
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    • 2018
  • The purpose of this study was to evaluate the efficacy of a multiple voice therapy technique ($SKMVTT^{(R)}$) using laughter for the treatment of various benign vocal fold lesions. To achieve this, 23 female patients diagnosed with vocal nodules, vocal polyp, and muscle tension dysphonia through videostroboscopy were enrolled in vocal hygiene and $SKMVTT^{(R)}$. All of the patients were treated once a week for 4 to 12 sessions. The GRBAS scale was used to confirm the changes in voice quality before and after the treatment. Acoustic analysis was performed to evaluate jitter, shimmer, NHR, fundamental frequency variation, amplitude variation, PFR, and dB range. Videostroboscopy was performed to confirm the changes in the laryngeal features before and after the treatment. After the $SKMVTT^{(R)}$, the results of the perceptual evaluation demonstrated that the G, R, and B scales significantly improved. An acoustic evaluation also demonstrated that jitter, shimmer, NHR, vAm, vFo, PFR, and dB range also significantly improved after the $SKMVTT^{(R)}$. In comparison to the videostroboscopic findings, the size of the vocal nodules and vocal polyp decreased or disappeared after the treatment. In addition, the size of the cuneiform tubercles decreased, the length of the aryepiglottic folds became longer, and the laryngeal findings of the supraglottic compressions improved after the $SKMVTT^{(R)}$. These results suggest that the $SKMVTT^{(R)}$ is effective in improving the vocal quality of patients with benign vocal fold lesions. In conclusion, it seems that laughter and inspiratory phonation suppressed abnormal laryngeal elevation and lowered laryngeal height, which seems to have the effect of improving hyperfunctional phonation.

엽록소형광을 이용한 한지형 잔디 3종의 하절기 활력도 비교 분석 (Comparison of Vitality among Three Cool-Season Turfgrasses during Summer using Chlorophyll Fluorescence)

  • 고석찬
    • 한국환경과학회지
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    • 제30권7호
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    • pp.547-555
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    • 2021
  • To compare the vitality among cool-season turfgrasses under summer weather conditions and to obtain information to improve the management of turfgrasses in golf courses and sports fields., the chlorophyll fluorescence of three cool-season turfgrasses commonly planted on golf courses in the Jeju area was measured. The turfgrasses were perennial ryegrass (Lolium perenne L.), Kentucky bluegrass (Poa pratensis L.), and creeping bentgrass (Agrostis palustris Huds.). In perennial ryegrass and Kentucky bluegrass, the chlorophyll index was low in early summer and high in late summer. In creeping bentgrass, it remained low throughout the study. Fo tended to be low in the early summer and high in late summer in the three turfgrasses. However, the difference in Fo between late summer and early summer was markedly higher in perennial ryegrass than in Kentucky bluegrass or creeping bentgrass. Fm tended to be low in early summer and high in late summer, without obvious differences among the three turfgrasses. Fv/Fm, a measure of photochemical efficiency, was also low in early summer and high in late summer in the three turfgrasses. However, Fv/Fm in late summer was mostly higher in Kentucky bluegrass and creeping bentgrass than in perennial ryegrass, indicating that the former are more resistant to the high temperature and humidity of late summer. Furthermore, Kentucky bluegrass had a high chlorophyll index in late summer and would be most resistant to the harsh conditions of late summer.

향상된 전력효율을 갖는 GaInP/GaAs HBT 마이크로파 푸쉬-푸쉬 전압조정발진기 (A Microwave Push-Push VCO with Enhanced Power Efficiency in GaInP/GaAs HBT Technology)

  • 김종식;문연국;원광호;신현철
    • 대한전자공학회논문지SD
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    • 제44권9호
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    • pp.71-80
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    • 2007
  • 본 논문은 교차결합된 부성저항(cross-coupled negative-gm) 발진기 구조의 캐패시터 공통단자에서 2차 고조파를 얻어내는 새로운 푸쉬-푸쉬 기술에 대해 제안한다. 캐패시터 공통단자에서 2차 고조파가 생성되는 기본적인 이론은 에미터-베이스 접합 다이오드의 비선형 특성에 의한 Voltage clipping과 VCO core 트랜지스터의 Switching 동작 시 생기는 상승과 하상 시간의 차로써 설명된다. Simulation을 통한 비교연구를 통하여 본 논문에서 제안한 방법이 기존의 에미터 공통단자에서 출력을 얻어내는 방법보다 마이크로파 영역에서 전력효율이 더 뛰어나다는 것을 보였다. 본 기술을 적용한 Prototype MMIC VCO가 12-GHz와 17-GHz 대역에서 GaInP/GaAs HBT 공정을 사용하여 설계, 제작되었다. 출력 파워는 각각 -4.3dBm과 -5dBm이 측정되었고, Phase noise는 1-MHz offset에서 각각 -108 dBc/Hz와 -110.4 dBc/Hz가 측정되어 -175.8 dBc/Hz와 -184.3 dBc/Hz의 FoM(Figure-of-Merit)을 얻었다. 제작된 12-GHz와 17-GHz의 VCO Core는 각각 25.7mW(10.7mA/2.4V)와 13.1mW(4.4mA/3.0V)를 소모한다.

상위 6비트를 공유하는 12 비트 SAR A/D 변환기 (12-bit SAR A/D Converter with 6MSB sharing)

  • 이호용;윤광섭
    • 전기전자학회논문지
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    • 제22권4호
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    • pp.1012-1018
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    • 2018
  • 본 논문에서는 IoT 센서 처리를 위한 1.8V 공급전압의 CMOS SAR(Successive Approximation Register) A/D 변환기를 설계하였다. 본 논문에서 2개의 A/D 변환기를 병렬로 사용하여 샘플링 속도를 향상시킨 12비트 SAR A/D 변환기를 제안한다. 2개의 A/D 변환기 중 1개의 A/D 변환기는 12자리 비트를 모두 결정하고, 또 다른 A/D 변환기는 다른 A/D 변환기의 상위 6비트를 그대로 사용하여 전력소모와 스위칭 에너지를 최소화하였다. 두 번째 A/D 변환기는 상위 6비트를 결정하지 않기 때문에 컨트롤 회로와 SAR 로직이 필요하지 않아 면적을 최소화하였다. 또한 스위칭 에너지는 커패시터 용량과 C-DAC 내 전압 변화가 클수록 값이 커지는데 두 번째 A/D 변환기는 상위 6비트를 결정하지 않아 스위칭 에너지를 줄일 수 있다. 또한 커패시터 내 스플릿 커패시터 용량을 유닛 커패시터 용량과 동일하게 회로를 구성하여 C-DAC 내 공정오차를 줄일 수 있다. 제안하는 SAR A/D 변환기는 180nm CMOS 공정을 이용하여 설계하였고, 1.8V의 공급전압, 10MS/s의 변환속도, 10.2비트의 ENOB(Effective Number of Bit)이 측정되었다. 핵심 블록의 면적은 $600{\times}900um^2$, 총 전력소모는 $79.58{\mu}W$, FoM(Figure of Merit)는 6.716fJ/step로 확인할 수 있다.