• Journal of the Korean Mathematical Society
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• v.54 no.6
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• pp.1733-1757
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• 2017

Let $R={\oplus}_{{\alpha}{\in}{\Gamma}}R_{\alpha}$ be an integral domain graded by an arbitrary torsionless grading monoid ${\Gamma}$, ${\bar{R}}$ be the integral closure of R, H be the set of nonzero homogeneous elements of R, C(f) be the fractional ideal of R generated by the homogeneous components of $f{\in}R_H$, and $N(H)=\{f{\in}R{\mid}C(f)_v=R\}$. Let $R_H$ be a UFD. We say that a nonzero prime ideal Q of R is an upper to zero in R if $Q=fR_H{\cap}R$ for some $f{\in}R$ and that R is a graded UMT-domain if each upper to zero in R is a maximal t-ideal. In this paper, we study several ring-theoretic properties of graded UMT-domains. Among other things, we prove that if R has a unit of nonzero degree, then R is a graded UMT-domain if and only if every prime ideal of $R_{N(H)}$ is extended from a homogeneous ideal of R, if and only if ${\bar{R}}_{H{\backslash}Q}$ is a graded-$Pr{\ddot{u}}fer$ domain for all homogeneous maximal t-ideals Q of R, if and only if ${\bar{R}}_{N(H)}$ is a $Pr{\ddot{u}}fer$ domain, if and only if R is a UMT-domain.

• Journal of Navigation and Port Research
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• v.45 no.4
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• pp.204-211
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• 2021

The Maritime Domain Awareness system is a component that is necessary to enhance the awareness of all situations occurring at sea in relation to security, safety, economy, and the environment. To establish a marine situation recognition system that is currently being introduced in major maritime countries after approval by the International Maritime Organization's Maritime Safety Committee in 2010, operational measures should be established. For the purpose of establishing a technological foundation for the efficient construction of a Korean maritime situation recognition system, this study analyzed the status of each system (RADAR, VHF, and V-PASS, etc.) and proposed the application of data and communication standards.

• Korean Journal of Mathematics
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• v.19 no.3
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• pp.255-261
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• 2011

Let D be an integral domain, S be a torsion-free grading monoid such that the quotient group of S is of type (0, 0, 0, ${\ldots}$), and D[S] be the semigroup ring of S over D. We show that D[S] is an H-domain if and only if D is an H-domain and each maximal t-ideal of S is a $v$-ideal. We also show that if $\mathbb{R}$ is the eld of real numbers and if ${\Gamma}$ is the additive group of rational numbers, then $\mathbb{R}[{\Gamma}]$ is not an H-domain.

• Journal of the Korean Mathematical Society
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• v.48 no.1
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• pp.191-205
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• 2011

It is well known that for a Krull domain R, the divisor class group of R is a torsion group if and only if every subintersection of R is a ring of quotients. Thus a natural question is that under what conditions, for a non-Krull domain R, every (t-)subintersection (resp., t-linked overring) of R is a ring of quotients or every (t-)subintersection (resp., t-linked overring) of R is at. To address this question, we introduce the notions of *-compact packedness and *-coprime packedness of (an ideal of) an integral domain R for a star operation * of finite character, mainly t or w. We also investigate the t-theoretic analogues of related results in the literature.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.26 no.7
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• pp.1262-1269
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• 2002

It is inevitable to evaluate the life of turbine rotor because the operating periods of power plants need to be extended. For the test, seven kinds of specimens with different degradation levels were prepared by the isothermal heat treatment at $630^{\circ}C$. Magnetic methods utilizing Barkhausen noise coercive force($BN_c$) were applied to detect the degradation caused by thermal aging. Magnetic property of material is related with domain dynamics and that is affected by the microstructure of material. Therefore $BN_c$ is very sensitive to the microstructure change of the material. With the increase of degradation, $BN_c$ was decreased and this phenomenon is considered due to precipitations and grain size. The result was compared with Vickers hardness($H_v$) and coercive force($H_c$) to detect the relative variation, and was related with $H_v$ and YS to estimate the change of the mechanical properties with the degradation.

• Proceedings of the KSME Conference
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• 2001.06a
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• pp.250-255
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• 2001

It is inevitable to evaluate the life of turbine rotor because the operating periods of power plants need to be extended. The magnetic methods utilizing Magnetic Barkhausen noise curve were applied to detect the degradation caused by thermal aging. The Magnetic property of material depends on the domain dynamics and it is affected by the microstructure of material. Therefore the magnetic property is very sensitive to the microstructure change of the material. It is, thus, very useful to detect the state of degradation of varying materials. The test specimen made of 1Cr-1Mo-0.25V steel was used widely for turbine rotor material, and seven kinds of specimens with different degradation levels were prepared by the isothermal heat treatment at $630^{\circ}C$. With the increase of degradation, BHN was decreased. The result was compared with coercive force and vickers hardness.

• Journal of fish pathology
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• v.35 no.1
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• pp.121-128
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• 2022

Recent studies revealed that histone proteins are involved in innate immune responses during pathogen invasion as well as DNA packing. This study characterized the histone genes (H2A.V) of sevenband groupers and analyzed gene expression in NNV-infected sevenband groupers. The open reading frame (ORF) of H2A.V is 387 bp which encoded 128 amino acid residues. The deduced amino acid sequence of H2A.V harbor a highly conserved domain for H2A/H2B/H3 and H2A_C binding domain. Quantitative real-time PCR analysis showed that H2A.V had a high gene expression level in the brain and blood after being NNV-infected. An increase in extracellular histone protein in the blood has been identified as a biomarker for vascular function in humans. More research is required to understand histone's immune response at the protein level or in aquatic animals.

• Journal of Ginseng Research
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• v.47 no.1
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• pp.23-32
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• 2023

Coronavirus disease 2019 (COVID-19) is a highly infectious respiratory disease caused by a severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2). SARS-CoV-2 infection may cause clinical manifestations of multiple organ damage, including various neurological syndromes. There are currently two oral antiviral drugs-Paxlovid and molnupiravir-that are recognized to treat COVID-19, but there are still no drugs that can specifically fight the challenges of SARS-CoV-2 variants. Nucleotide-binding oligomerization domain-like receptor pyrin domain-containing-3 (NLRP3) inflammasome is a multimolecular complex that can sense heterogeneous pathogen-associated molecular patterns associated with neurological disorders. The NLRP3 activation stimulates the production of caspase-1-mediated interleukin (IL)-1β, IL-18, and other cytokines in immune cells. Panax (P.) ginseng is a medicinal plant that has traditionally been widely used to boost immunity and treat various pathological conditions in the nervous system due to its safety and anti-inflammatory/oxidant/viral activities. Several recent reports have indicated that P. ginseng and its active ingredients may regulate NLRP3 inflammasome activation in the nervous system. Therefore, this review article discusses the current knowledge regarding the pathogenesis of neurological disorders related to COVID-19 and NLRP3 inflammasome activation and the possibility of using P. ginseng in a strategy targeting this pathway to treat neurological disorders.

• IMMUNE NETWORK
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• v.10 no.2
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• pp.35-45
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• 2010

Background: Expression of recombinant antibodies and their derivatives fused with other functional molecules such as alkaline phosphatase in Escherichia coli is important in the development of molecular diagnostic reagents for biomedical research. Methods: We investigated the possibility of applying a well-known Fos-Jun zipper to dimerize $V_H$ and $V_L$ fragments originated from the Fab clone (SP 112) that recognizes pyruvate dehydrogenase complex-E2 (PDC-E2), and demonstrated that the functional zipFv-112 and its alkaline phosphatase fusion molecules (zipFv-AP) can be produced in the cytoplasm of Origami(DE3) trxB gor mutant E. coli strain. Results: The zipFv-AP fusion molecules exhibited higher antigen-binding signals than the zipFv up to a 10-fold under the same experimental conditions. However, conformation of the zipFv-AP seemed to be influenced by the location of an AP domain at the C-terminus of $V_H$ or $V_L$ domain [zipFv-112(H-AP) or zipFv-112(L-AP)], and inclusion of an AraC DNA binding domain at the C-terminus of VH of the zipFv-112(L-AP), termed zipFv-112(H-AD/L-AP), was also beneficial. Cytoplasmic co-expression of disulfide-binding isomerase C (DsbC) helped proper folding of the zipFv-112(H-AD/L-AP) but not significantly. Conclusion: We believe that our zipFv constructs may serve as an excellent antibody format bi-functional antibody fragments that can be produced stably in the cytoplasm of E. coli.

• Journal of the Korean Ceramic Society
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• v.52 no.5
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• pp.299-303
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• 2015

The electrolyte is an important component in determining the performance of Fuel Cells. Especially, investigation of the conduction properties of electrolytes plays a key role in determining the performance of the electrolyte. The electrochemical properties of Yttrium stabilized zirconia (YSZ) were measured to allow the use of this material as an electrolyte for solid oxide fuel cells (SOFC) in the temperature range of $700-1000^{\circ}C$ and in $0.21{\leq}pO_2/atm{\leq}10^{-23}$. A Hebb-Wagner polarization experimental cell was optimally manufactured; here we discuss typical problems associated with making cells. The partial conductivities due to electrons and holes for 8YSZ, which is known as a superior oxygen conductor, were obtained using I-V characteristics based on the Hebb-Wagner polarization method. Activation energies for holes and electrons are $3.99{\pm}0.17eV$ and $1.70{\pm}0.06eV$ respectively. Further, we calculated the oxygen ion conductivity with electron, hole, and total conductivity, which was obtained by DC four probe conductivity measurements. The oxygen ion conductivity was dependent on the temperature; the activation energy was $0.80{\pm}0.10eV$. The electrolyte domain was determined from the top limit, bottom limit, and boundary (p=n) of the oxygen partial pressure. As a result, the electrolyte domain was widely presented in an extensive range of oxygen partial pressures and temperatures.