• 대한한의학회지
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• 제20권3호
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• pp.66-76
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• 1999

The purpose of this study was to asses the etlect of Uncaria rhynchophylla (UR). one of the oriental herbs having a capability to block calcium channels, on affecting vestibular compensation (VC) in Sprague - Dawley rats. Animals were divided into a drug treatment group receiving, UR per oral for 10 days preceding unilateral labyrinthectomy (ULX) and a control group with saline ingestion, To evaluate behavioral changes. horizontal spontaneous nystagmus (SN) and roll head tilt (RHT) were recorded by a video camem with zoom lens in the course of vestibular compensation (VC). Immunohistochemical staining was performed by conventional ABC method to visualize cFos-like immunoreactive (cFLI) neurons in the medial vestibular nuclei (MVN) and cFLI cells were counted by image analyzer. Bodyweight was increased significantly, about 35g, by UR treatment for 10 clays before ULX. Compared with the control group, the drug group showed significant reduction of RHT 6 hrs after ULX as well as fast disappearance of SN at early stages of vestibular compensation. Also, recovery of the spatial and temporal cFLI expressions in the bilateral MVN was accelerated 24 hrs after ULX. These results suggest that Uncaria rhynchophyila has a beneficial effect to ameliorate vestibular compensation in unilateral labryinthectomized rats.

• Advances in pediatric surgery
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• 제13권2호
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• pp.187-193
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• 2007

Contralateral exploration in children with unilateral inguinal hernia is controversial. This study was done to identify risk factors for the development of contralateral inguinal hernia in patients with unilateral inguinal hernia. The clinical experience of 4,206 inguinal hernias repaired by one pediatric surgeon on 3,358 children at HanYang University Hospital from September 1979 to December 2002 was analyzed. 1,868 (55.6%) hernias occurred on right side, 1,190 (35.4%) on left side, and 300 (8.9%) were bilateral. 2,702 children were boys and 656 were girls (M:F = 4.1:1). 170 children of 3,058 children with unilateral hernias (5.6%) developed contralateral inguinal hernia at 1 day to 95 months after herniotomy. 146 children were boys and 24 were girls (M:F = 6.1:1). The patients who had had herniotomy before 1 year of age developed contralateral hernia in 17.4%, compared with 5.6% overall average. The earlier the first herniotomy was performed, the more frequently contralateral hernia developed. The occurrence of contralateral inguinal hernia was more frequent in boys (146 of 2,460, 5.9%) than girls (24 of 598, 4.0%) and more frequent after left herniotomy (80 of 1,190, 6.7%) than after right herniotomy (90 of 1,868, 4.8%), but statistically not significant. 52.9% of contralateral inguinal hernia developed within 1 year after hernia repair, and 87.6% developed within 3 years. Routine exploration on contralateral side in children is not necessary.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제39권
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• pp.12.1-12.5
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• 2017

Background: Rehabilitation of normal function and form is essential in cleft lip repair. In 2005, Dr. David M. Fisher introduced an innovative method, named "an anatomical subunit approximation technique" in unilateral cleft lip repair. According to this method, circumferential incision along the columella on cleft side of the medial flap is continued to the planned top of the Cupid's bow in straight manner, which runs parallel to the unaffected philtral ridge. Usually, small inlet incision is needed to lengthen the medial flap. On lateral flap, small triangle just above the cutaneous roll is used to prevent unesthetic shortening of upper lip. This allows better continuity of the Cupid's bow and ideal distribution of tension. Case presentation: As a modification to original method, orbicularis oris muscle overlapping suture is applied to make the elevated philtral ridge. Concomitant primary rhinoplasty also results in good esthetic outcome with symmetric nostrils and correction of alar web. As satisfactory results were obtained in three incomplete and one complete unilateral cleft lip patients, indicating Fisher's method can be useful in cleft lip surgery with functional and esthetic outcome. Conclusions: Clinically applied Fisher's method in unilateral cleft lip patients proved the effectiveness in improving the esthetic results with good symmetry. This method also applied with primary rhinoplasty.

• 대한후두음성언어의학회지
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• 제30권1호
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• pp.28-33
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• 2019

Background and Objectives : Laryngeal electromyography (LEMG) is valuable to evaluate the innervation status of the laryngeal muscles and the prognosis of vocal fold paralysis (VFP). However, there is a lack of agreement on quantitative interpretation of LEMG. The aim of this study is to measure the motor unit action potentials (MUAP) quantitatively in order to find cut-off values of amplitude, duration, phase for unilateral vocal fold paralysis patients. Materials and Method : Retrospective chart review was performed for the unilateral VFP patients who underwent LEMG from March 2016 to May 2018. Patient's demography, cause of VFP, vocal cord mobility, and LEMG finding were analyzed. The difference between normal and paralyzed vocal folds and cut-off values of duration, amplitude, and phase in MUAP were evaluated. Results : Thirty-six patients were enrolled in this study. Paralyzed vocal fold had significantly longer duration (p=0.021), lower amplitude (p=0.000), and smaller phase (p=0.012) than the normal. The cut-off values of duration, amplitude, and phase in MUAP for unilateral VFP were 5.15 ms, $68.35{\mu}V$, and 1.85 respectively. Conclusion : An analysis of MUAP successfully provided quantitative differences between normal and paralyzed vocal folds. But, additional research is needed to get more available cut-off value which is helpful to evaluate the status of laryngeal innervations.

• 대한치과보철학회지
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• 제57권1호
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• pp.42-48
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• 2019

하악 편측에 소수의 잔존치만 있는 증례에서 통상적인 국소의치로 수복하는 경우에 충분한 유지 및 저항을 얻기 어렵고, 무치악 치조제의 흡수에 따른 의치의 안정성 저하로 인해 잔존지대치에 유해한 힘이 가해질 것으로 예상된다. 이러한 경우에 다수의 임플란트를 이용한 고정성 보철로 수복하게 되면 여러 가지 장점이 있을 수 있으나, 해부학적, 경제적 요인에 의해 치료 방법으로 선택이 제한될 수 있다. 이에, 적은 수의 임플란트를 전략적 위치에 식립하여 임플란트 보조 국소의치(Implant-assisted removable partial denture, IARPD)의 제작을 대안으로 고려해 볼 수 있다. 본 증례보고에서는 전통적인 가철성 국소의치만으로는 적절한 지지, 유지, 안정이 어려운 두 임상증례에서 소수의 임플란트를 전략적 위치에 식립하고 로케이터(Locator) 부착장치를 적용하여 3년간 경과관찰을 통해 좋은 임상 결과를 확인하였기에 이를 보고하고자 한다.

• 한국음향학회지
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• 제41권1호
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• pp.45-51
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• 2022

음질평가는 물리적 음향 자극에 대해 주관적으로 지각되는 음색을 평가한다는 측면에서 심리음향학적 측정과 관련이 있다. 본 논문은 인공와우 사용자의 음질평가를 위한 예비연구로서 바이모달 인공와우 사용자를 대상으로 음질평가를 시행하고 인공와우만 착용했을 때와 바이모달을 착용했을 때의 음질평가 차이를 파악하고자 하였다. 총 13명의 바이모달 인공와우 사용자와 7명의 편측 인공와우 사용자가 연구에 참여하였고 순음 및 어음 청력검사, 보청기 기능이득과 실이삽입이득을 측정하였다. 음질평가에서는 바이올린소리, 남자와 여자 노래소리, 냉장고 소음의 4개 음향자극을 방음실에서 들려주고 6개 음질평가 항목에 대해 0에서 10까지의 척도로 표시하도록 하였다. 검사결과 바이모달 사용자는 편측 인공와우만 착용했을 때보다 바이모달을 착용했을 때 음질평가 5개 항목에서 0.8점 높았고, 바이모달 사용자와 편측 인공와우 사용자 그룹간 비교에서는 두 그룹 사이에 차이를 보이지 않았다. 주관적 측면의 바이모달 혜택 측정을 위해서 좀 더 체계적인 음질평가 도구와 방법에 대한 후속 연구가 필요할 것으로 생각된다.

• 대한수의학회지
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• 제62권3호
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• pp.26.1-26.7
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• 2022

This study was aimed to evaluate the prophylactic anti-glaucoma effect of topical 5% betaxolol (BTX) and 2% dorzolamide (DRZ) on the second eye in dogs with unilateral primary angle closure glaucoma (PACG). Medical records of 60 dogs with unilateral PACG who received prophylactic anti-glaucoma eyedrops in the second eye, from 2016 to 2021, were reviewed. The prophylactic effects of BTX were maintained on 28/60 (46.7%) eyes until last visit and BTX failure was observed on median 510 (range, 53-1,927) days in 32/60 (53.3%) eyes. After DRZ instillation in BTX failure eyes, the prophylactic effects were extended at median 610 (range, 157-2,270) days in 21/32 (65.6%) eyes. DRZ failure eyes (17/21, 81.0%) eyes required chemical ablation or surgical intervention due to uncontrolled intraocular pressure. The duration of prophylactic effects was decreased with aging (R² = 0.334, p = 0.006). The predominant breeds were Shih-Tzu (41.9%) and American Cocker Spaniel (30.6%) with no significant differences in survival curves (p = 0.210). The average prophylactic effects of BTX persisted more than 1.5 year and could be selected the first prophylactic eye drop in unilateral PACG. Also, early surgical intervention should be considered in prophylactic medications failure cases.

• Journal of Korean Neurosurgical Society
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• 제65권4호
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• pp.531-538
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• 2022

Objective : Anterior communicating artery (Acom) aneurysm is one of the most common intracranial aneurysms, constituting approximately 30-35% of all aneurysm formation in the brain. Anatomically, the H-complex (the anatomic morphology of both A1 to A2 segments) is thought to affects the nature of the Acom aneurysm due to its close relationship with the hemodynamics of the vessel. Therefore, we investigated the relative risk factors of aneurysmal rupture, especially focusing on H-complex morphology of the Acom. Methods : From January 2016 to December 2020, a total of 209 patients who underwent surgery, including clipping and coiling for Acom aneurysm in our institution were reviewed. There were 102 cases of ruptured aneurysm and 107 cases of unruptured aneurysm. The baseline morphology of aneurysms was investigated and the relationship between the H-complex and the clinical characteristics of patients with Acom aneurysms was assessed. Results : Of the 209 patients, 109 patients (52.1%) had symmetrical A1, 79 patients (37.8%) had unilateral hypoplastic A1, and 21 patients (10.0%) had aplastic A1. The hypoplastic A1 group and the aplastic A1 group were grouped together as unilateral dominancy of A1, and were compared with the symmetrical A1 group. There was no significant difference in demographic characteristics and radiological findings of Acom aneurysms between two groups. However, when dichotomizing the patients into ruptured cases and unruptured cases, unilateral dominance of the A1 segment was associated with aneurysmal rupture with statistical significance (p=0.011). Conclusion : These results suggest that the unilateral dominance of the A1 segment does not have a significant effect on the morphology of Acom aneurysms, but contributes to aneurysmal rupture. Thus, we can better understand the effects of hemodynamics on Acom aneurysm.

• 대한영상의학회지
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• 제83권2호
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• pp.372-377
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• 2022

일측성 폐정맥 폐쇄는 총폐정맥이 좌심방내로 연결되는 못하는 드문 심혈관계 기형이다. 일측성 폐정맥 폐쇄는 흔히 어린 시기에 진단이 되며, 성인이 된 이후에 진단이 되는 경우는 극히 드물다. 성인 환자에서 활동 시 호흡곤란과 객혈이 흔한 임상증상이다. 폐실질의 이상은 폐정맥 폐쇄의 간접적인 소견이며, 간질성 폐질환으로 나타날 수 있다. 우리는 62세 여자 환자에서 일측성 간질성 폐질환을 보이는 일측성 폐정맥 폐쇄의 증례와 12년간의 흉부 X선 사진 소견의 변화를 보고하고자 한다.

• 대한치과교정학회지
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• 제25권3호
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• pp.311-321
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• 1995

이상적 교합이란 치아의 교합이 저작계의 다른 부분과 기능적으로 조화를 이루고, 중심교합상태에서 양측으로 동시에 균일한 접촉을 이루는 것을 말한다. 악골의 양측을 이용한 균형된 저작은 양측의 균등한 견치유도와 기능적 능력에 의해 가능해지지만 교합간섭이나 저작계에 대한 기능적 요구의 감소로 좌우측중 어느 한쪽만을 선호하는 편측저작양상이 유도되기도 한다. 편측저작은 악골의 발육 교합 및 안면의 전체적인 형태에 이르기까지 악안면 전체에 형태적, 기능적인 부전을 초래할 잠재성을 가진 증상이나 이에 대한 연구가 많지 않다. 본 연구는 저작습관의 분포를 알아보고, 저작습관에 따른 교합력의 차이와 안면골격형태를 비교 연구할 목적으로 시도하였다. 부산대학교 치과대학 재학생 186명을 대상으로 설문지를 이용하여 저작습관에 따라 양측저작군과 편측저작군으로 나누어 저작습관의 분포를 조사하였고, 이 중 두개안면부의 성장발육에 영향을 미칠만한 질병에 이환되지 않았고 측모가 양호하며 Angle분류 I급의 교합상태를 보이면서 교정치료와 보철치료를 받은 경험이 없고 악관절 질환이 없는 자 중 양측저작자와 편측저작자 각각 25명을 선정하여 교합력계(MPM 3000)를 이용하여 최대교합력을 측정하고, 정모두부방사선규격사진을 촬영하여 안면골격형태를 비교연구하여 다음과 같은 결과를 얻었다. 1. 저작습관은 양측저작자($68\%$)가 많았으며, 편측저작자 중 $68\%$는 우측을, $32\%$는 좌측의 저작을 선호하였다. 2. 양측저작군은 좌우측의 최대교합력이 비슷하였고, 편측저작군은 저작측이 비저작측보다 교합력이 컸으며 특히 여자에서 그 차가 뚜렷하였다. 편측저작군은 양측저작군에 비해 저작측은 교합력이 컸으며, 비저작측은 작았지만 유의성은 없었다. 저작습관에 상관없이 남자가 여자보다 교합력이 컸으며 남자는 여자의 교차력의 약2배정도이었다. 남녀를 합한 경우 편측저작군의 저작측은 양측저작군의 교합력과 비슷하였으나 비저작측은 그것보다 작았다. 3. 정모두부방사선규격사진을 이용하여 안면골격형태를 비교한 결과 양측저작군의 좌우측, 편측저작군의 저작측과 비저작측간에 차이가 없었다.