• BMB Reports
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• 제51권3호
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• pp.106-118
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• 2018

How the organ size is adjusted to the proper size during development and how organs know that they reach the original size during regeneration remain long-standing questions. Based on studies using multiple model organisms and approaches for over 20 years, a consensus has been established that the Hippo pathway plays crucial roles in controlling organ size and maintaining tissue homeostasis. Given the significance of these processes, the dysregulation of the Hippo pathway has also implicated various diseases, such as tissue degeneration and cancer. By regulating the downstream transcriptional coactivators YAP and TAZ, the Hippo pathway coordinates cell proliferation and apoptosis in response to a variety of signals including cell contact inhibition, polarity, mechanical sensation and soluble factors. Since the core components and their functions of the Hippo pathway are evolutionarily conserved, this pathway serves as a global regulator of organ size control. Therefore, further investigation of the regulatory mechanisms will provide physiological insights to better understand tissue homeostasis. In this review, the historical developments and current understandings of the regulatory mechanism of Hippo signaling pathway are discussed.

• 한국복합재료학회:학술대회논문집
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• 한국복합재료학회 2000년도 추계학술발표대회 논문집
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• pp.238-244
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• 2000

FBGs have been extensively used as strain sensors or temperature sensors in a variety of applications related to composites because of embedding ability, small size and multiplexing capability. We inspected embedding environments inside composites with optical fiber by microscope analysis and birefringence characteristics of FBG embedded into textile composite laminate by cure monitoring using a high power WSFL. The cure monitoring of the cases with the striped FBG and the recoated FBG provided comprehensive understandings about the birefringence effect induced by the transverse stress. And these results allowed to consider a recoating method as an important tool to relieve birefringence.

• 수산해양교육연구
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• 제24권1호
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• pp.25-33
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• 2012

Though science and technology are evolving rapidly in recent years, the traditional science education has limits for students to be satisfied their interests and needs because they couldn't follow these speeds. STEAM as a education integrating science, technology, engineering, arts and mathematics has strengths of increasing interests and understandings in science and technology and improving integrated thinking and problem solving ability for leaners. In this study we analyze the elementary school curriculum and construct physics learning based on STEAM and develop a android application to increase interests in science and improve problem solving ability. In the future, we need to analyze and develop the curriculum and contents for the STEAM education.

• 한국철도학회:학술대회논문집
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• 한국철도학회 2000년도 춘계학술대회 논문집
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• pp.598-605
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• 2000

The design of a current collection system of high speed train requires the fundamental understandings fer the dynamic characteristics of a catenary system and pantograph. The stiffness of the catenary system of high speed train has the varying characteristics for the change of the contact point with a pantograph, since the supporting pole and hanger make the different boundary conditions for the updown stiffness of a trolley wire. The variation of stiffness results in Mathiue equation, which characterizes the stability of the system. However, the two terms variation of the stiffness due to span length and hanger distance cannot be solved analytically. In this paper, the stiffness variations are calculated, and the physical reasoning of linear model and one term Mathieu equation are reviewed. And the numerical analysis for the two term variation of the stiffness is done for the several design parameters of the pantograph.

• Journal of Ship and Ocean Technology
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• 제7권3호
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• pp.56-65
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• 2003

The hull monitoring systems of container ships with four long-base gages give enough information for identifying the hull girder loads such as bending and torsional moments. But such a load-identification for container ships has not been known. In this paper, a load-identification method is suggested in terms of a linear matrix equation that the measured strain vector equals to the multiplication of the transformation matrix and the desired strain component vector. The equation is proved to be mathematically complete by the property of positive-definite determinant of the transformation matrix. The method is applied to a hull stress monitoring system for 8100TED container ship during sea trial, and the estimated external loads illustrate reasonable results in comparison with the pre-estimated results. This moment decomposition concept has also been tested in real operation conditions. The typical phenomena over the Suez Canal illustrated very suitable results comparing with the physical understandings. Henceforth, one can effectively use the proposed concept to monitor the hull girder loads such as bending and torsional moments.

• 한국컴퓨터정보학회논문지
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• 제20권11호
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• pp.127-133
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• 2015

In this paper, we propose that college counselors be more knowledgable of adult ADHD symptoms and develop better understandings of subtypes of the disorder. The findings in this study show that college students with different subtypes of ADHD symptoms experience different types of psychological maladjustment as well as different levels of psychological distress. Specifically, combined-type trait group show the highest levels of each of subscale of SCL-90-R among the other groups (i.e., normal, predominant inattentive subtype, hyperactive-impulsive type). Furthermore, combined typed trait group show significantly higher levels of animosity and paranoid ideation than the others. Therefore, college counselors need to provide effective interventions addressing intense emotion and cognitive distortion among college students with ADHD combined symptoms.

• Advances in materials Research
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• 제5권2호
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• pp.81-92
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• 2016

Stress concentration is an interesting and essential field of study, as it is the prime cause of failure of structural parts under static load. In the current paper, stress and strain concentration factors in unidirectional functionally graded (UDFGM) plate with central circular cutout are predicted by carrying out a finite element study on ANSYS APDL platform. The present study aims to bridge the lacuna in the understandings of stress analysis in perforated functionally graded plates. It is found that the material variation parameter is an important criterion while designing a perforated UDFGM plate. By selecting a proper material variation parameter and direction of material gradation, the stress and strain concentrations can be significantly reduced.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2004년도 하계학술대회 논문집 B
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• pp.1046-1048
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• 2004

Inductance is an important parameter determining the characteristics of current waveform in electric motors. There are many kinds of inductances, however, self and mutual inductances are the major components. These inductances are changed under the variation of the magnetic circuit, current, frequency etc., even in the same winding distribution. Therefore this paper deals with the characteristics of inductance according to the shape of stator tooth. The analysis model is newly developed motor made of SMC(Soft Magnetic Composite) to reduce the core loss in high speed. the result of this paper gives the basic understandings of inductance to extend the applications of the motors.

• 대한수학교육학회지:수학교육학연구
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• 제10권1호
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• pp.103-113
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• 2000

A case study was conducted to investigate the understandings of the subject matter knowledge and pedagogical content knowledge held by 63 elementary preservice teachers in dealing with the division by a fraction. The study results showed that, in terms of the subject matter knowledge, the preservice teachers did not have a conceptual understanding of the division by a fraction and, in terms of the pedagogical content knowledge, they depended heavily on algorithms without a conceptual understanding of the meaning of the division by a fraction.

• 대한공간정보학회지
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• 제10권5호
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• pp.29-43
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• 2002

Accesses to lands, houses, the Internet and other utilities are regarded as basic human needs to escape poverty and are required to recognize the relationships between the digital divide and socio-economical inequality. The digital divide might not be a single technical disparity, but stems from a complicated mixture of economic and socio-technical symptoms of inequality. There is growing awareness of scrutinizing causal mechanisms between the digital divide and poverty since combating poverty could be a primary step to mitigate the digital divide. In this paper, the Hexad model is proposed to explicate poverty interpretation by using 6 parameters as a major tool for partly assisting in poverty monitoring system in connection with land information. A solution model of the Internet is suggested to break the digital divide. It expounds a conceptual framework and new idea for poverty management to notify spatio-temporal locations of poor actors and geography of the digital divide when efforts of poverty eradication hinge on understandings of geographic location of digital disadvantaged groups through parcel-based land information.