A kinetic profile of the catalytic domain of stromelysin-1 (SCD) using the fluorescent peptide substrate has been determined by the stopped-flow technique. The pH profile has a pH optimum of about 5.5 with an extended shoulder above pH 7. Three pKa values, 5.0, 5.7, and 9.8 are found for the free enzyme state and two pH independent Kcat/Km values of 4.1$\times$104 M-1 s-1 and 1.4$\times$104 M-1 s-1 at low and high pH, respectively. The profile is quite different in shape with other MMP family which has been reported, having broad pH optimum with two pKa values. The substrate specificity of SCD towards fluorescent heptapeptide substrates has been also examined by thin layer chromatography. The cleavage sites of the substrates have been identified using reverse-phase HPLC method.SCD cleaves Dns-PLA↓L↓WAR and Dns-PLA↓L↓FAR at two positions. However, the Dns-PLA↓LRAR, Dns-PLE↓LFAR, adn Dns-PLSar↓LFAR are cleaved exclusively at one bond. The double cleavages of Dns-PLALWAR and Dns-PLALFAR by SCD are in marked contrast to the close structurally related matrilysin. A notable feature of SCD catalysis agrees with the structural data that the S1' pocket of SCD is deeper than that of matriysin. The differences observed between SCD and matrilysin may form the basis of understanding the structural relationships and substrate specificities of the MMP family in vivo.
Journal of Family Resource Management and Policy Review
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v.9
no.3
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pp.97-112
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2005
This research has studied the people's perception and understanding of the 'Healthy Family Act' that has been enacted and practised from the year 2005. For this purpose, a survey has been conducted during October 2004 in several central and local cities in Korea, including Seoul, and a total of 741 samples have been used for the final analysis. The results of this study is as follows. The participants showed a very low level of recognition of the 'Healthy Family Act', and they Perceived that establishing a home-friendly atmosphere was of primary importance among the tasks that should be conducted by the State and local governments to encourage 'healthy families' The participants chose 'supporting the mental & physical health of family members' for the government supporting programs to make healthy families, and chose 'healthy life cultures such as clothes, food, and housing' for the government programs to support the everyday living cultures of the people. 1 Two thirds(2/3) of the participants indicated a willingness to participate in voluntary activities, and more than half of the participants said that they will participate in educational programs. Also, the participants indicated that divorce counselling should be offered only to the people who want the counselling, and as far as 'contents' are concerned, the participants indicated that 'the upbringing of children' should be the most important subject of the counselling. Finally, the participants indicated a willingness of participating educational programs in the order of parent education, family ethics education, realization of family values and family life education.
The purpose of this study is to examine the information search behavior of medical consumers visiting a hospital, and investigate the consumption values of medical consumers, classified according to the information search behavior, and characteristics of online health and disease information. This study also tried to identify the factors affecting medical consumers classified according to information search behavior, and gain an extensive understanding of medical consumers'consumption values and online information use. The analysis results of this study are as follows: First, the consumption values of medical consumers were classified into a total of 7 factors, i.e. future-positive value, family-oriented value, sustainablehealth value, rational-progressive value, social-cooperative value, socialachiever value and hedonistic-individual value. Next, the characteristics of medical consumers'online information search behavior were classified into three types of consumer groups, i.e. the limited information-oriented consumer group, the practical information-oriented consumer group and the passionate information-oriented consumer group. Second, the analysis of the differences among the three groups classified according to the characteristics of the information search behavior in terms of consumption values, use of online information sources, utility and the intention to reuse online information showed that all the differences were statistically significant. The passionate information-oriented consumer group showed the highest scores in the sustainable-health value, the social-achiever value and the hedonisticindividual value. Third, the factors affecting medical consumers, classified into three groups according to the characteristics of the information search behavior, were found to be socio-demographic variables like consumers' age and occupation, consumers'consumption values, use of online information sources, and utility of online information. This study tried to understand what values medical consumers have according to the differences in the information search behavior by examining the consumption values of medical consumers according to the information search behavior. The significance of this study lies in the fact that consumption values are instrumental in understanding medical consumers by identifying the fundamental motives and desires of consumers' behavior.
Family tourism has become the mainstream demand of the tourism market, and it is also an effective way to obtain happiness. This paper takes family tourists as the research object, takes the family tourism family affection interaction behavior and the experience value relationship as the link, Empirically tests the family tourism "interaction behavior-social support-experience value" conceptual model and the relationship hypothesis. The results showed that interaction of family affection had a positive and significant effect on the functional, cognitive and emotional experience value of family tourists. Family interaction in family tourism has a significant positive impact on social support. Social support has significant positive effects on functional, cognitive, emotional and overall experiential values. This conclusion expands the theoretical and empirical research on the relationship between interaction behavior and experience value, and provides a basis for understanding the interaction behavior and experience value of family love from the perspective of tourism experience essence.
Journal of Korean Home Economics Education Association
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v.24
no.1
/
pp.1-20
/
2012
The study, published in the 2007 revised curriculum of Practical Arts and Technology and Home Economics textbook(16 species) of the 'human development and family members' area of learning content elements were analyzed. This analysis was conducted in order to evaluate that the 2007 revised curriculum of Practical Arts(Technology and Home Economics) has been made well Articulations. The criteria of Articulations is "Development of learning content, Repeating, Gaps, Reduction. Content criterias is 'human development and family' area. These include "human development, human relationships, marriage and family life, caring for family members and family welfare" of the four criteria and 14 content elements. The results of this analysis, the first content elements is "process of human development, characteristics of human development, family relationships, communication, dating and partner selection, the significance of marriage and family, understanding the basic concepts of family, family change and family problem solving". There was no content elements. content element is 'friendship'. content elements is 'Characteristics of human development', 'understanding of sex and pregnancy and childbirth'. Thus, in the new curriculum, a review of these Articulations are required. Especially, the 'friendship' and 'understanding of sex and pregnancy and childbirth' of the content element should be noted in the curriculum configuration because of content elements be Analyzed as or . Also 'values about marriage change' importance in the low fertility society is a big learning content elements need repeating. However, textbooks should reflect differences in the configuration will hakgyogeupgan. Meanwhile, 'changes in values about marriage' that it is necessary to deal with the repeatedly because of recentely society is The low fertility society, However, for this content element based on the differences between school level to appear the contents of textbooks, the textbook screening process will be provided with the correct guidance.
The purpose of this study is to explore the family as an interaction system, concentrating on the mutual influences between communication and family development; (1) how Communication patterns affect family relationships, and (2) how relationships among family members affect communication. In order to do this Galvin, Brommel used the following frame work; family is a system in which communication regulates cohesion and adaptability by a flow of message patterns through a defined network of evolving interdependent relationships. A family system consists of members, the relationships among them, the family attributes, the members attributes and an environment in which family functions. Within the framework of common cultural communication patterns, each family has the capacity to develop its own communication code based on the experiences of individual members and the collective family experience. Most of us develop our communication skills within the family context learning both the general cultural language and the specific familial communication code. Communication may be viewed as a symbolic, transactional process as the process of creating and sharing meanings. To say that communication is a process implies a continuous interaction of an indefinite large numbers of variables with a concomitant,. continuous change in the values taken by these variables. Finally the process implies change, Family functions include the primary functions of cohesion and adaptability, and supporting functions of family images, themes, boundaries, and biosocial issues. The primary functions reveal concepts integrated family interaction and supporting function, along with those of cohesion and adaptability, give shape to family life. the characteristics of developed relationships of richness, uniqueness efficiency, substitutability, pacing , openness spontaneity, and evaluation are reflected in the verbal and nonverbal behaviors with which family members negotiated a set of common meanings and develop thier own unique message system. The message system is the major element of communication process and influences both the form and the content of thier relationship and in create and share meanings. Family systems need to provide order and predictability for thier members, specifically focusing on communication rules and the networks by which messages are transmitted. Most rules emerge as a result of multiful interactions. There are basic rules and rules about rules, or metarules. Perceiving the rules of family system is very difficult because often family members don't think about the basic rules, much less the metarules. Breaking the rule may result in the creation of a new set because the system may recalibrate itself to accept more variety of behavior. Families develop communication networks to deal with the general issue. Family adaptability may be seen through the degree of flexibility in forming and reforming networks and networks become a vital part of the decision- making process and relate to the power dynamics operating within the family. Networks also play an integral part in maintaining the roles and rules operating with the family system. Thus networks and rules have mutual influence. The family -of -origin issues influence all aspects of family communication and account for many of the communication patterns, rules and networks and the role of the family -of-origin influences as a primary force for communication on behavior of newly forming systems. Each family system develops its own communication meanings. There is not one right way to communicate within a family but may be indefinitly large change of family life and communication behavior. Study on functional family communication helps to gain a better understanding of dynamics of family communication and ability of a new insight into the family.
The purpose of the current study is to investigate parents' understanding and needs for character education in early childhood and during elementary education and to suggest policy implications effective character education for young children. Using focus group interviews, we collected qualitative data from 14 mothers in Seoul, Korea. The mothers were unclear about the definition of character education for their children and about their role in teaching proper values during the early years of their children's development. Most mothers with preschoolers were satisfied with the character education their children were receiving, whereas mothers with children in elementary school were not satisfied with the character education provided by school. The mothers expressed their concerns about the reliability of the teachers and schools of their children. As policy implications, providing regular parent education, activating parent-teacher associations, and strengthening the partnership through support from the community are suggested.
Park, Hye-Jun;Yi, Soon-Hyung;Lee, Kang-Yi;Kim, Bo-Kyung;Park, Sae-Rom
Child Studies in Asia-Pacific Contexts
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v.2
no.2
/
pp.109-122
/
2012
Despite the fact that Muslims are fast becoming part of the world population, they are the least known group. Moreover, Muslims have been seriously misunderstood and negatively perceived because of several tragic events related to terrorist attacks or wars in the Middle East countries. In this light, the current study examined how parenting values and practices varied by importance of religion, gender, and generation, based on the questionnaire data collected from 312 Muslim fathers and mothers living in Jakarta, Indonesia. The most salient result of this study was that the religion was at the center of everyday lives. The importance of religion in their lives clearly translated in their parenting styles by engaging in religious practices with their children. At the same time, Muslim parents in Indonesia had a high level of expectation for their children's education and making happy family life as well as being faithful as Muslim. This study contributed to promoting cultural sensitivity towards Muslims by examining Indonesian Muslim parents' parenting values and practices.
The purpose of the study is to examine the characteristics of the ideal housing for the modern family suggested by the Home Exposition (September, 1915) under the Japanese colonial rule in the macroscopic context of social change and the microscopic context of family. Through this research, we expect to have a partial understanding not only of changes in the outward appearance of traditional housing spaces during the civilization period and the early Japanese colonial rule when foreign cultures began to be introduced but also of families'residential lives and the patterns of change in people's consciousness of housing. Major conclusions from the current analysis are as follows. First, there were some changes in family paradigm induced through a home exhibition. Second, the most important factor for an ideal housing was that it must be the source of harmonic and healthy family life. Third, the importance of an appropriate space norm should be emphasized by providing the minimum size of each room. Fourth, the significance of the housing values of the economy, convenience, and hygiene should be emphasized for the ideal housing. Lastly, it was implied that for an ideal housing, the social and psychological aspects of housing must be satisfied along with the physical aspects. The limitation was that the model of ideal family housing presented in the Home Exposition cannot exclude the characteristics of the colonial perspectives in that it was followed by the model for the Japanese families.
International Journal of Advanced Culture Technology
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v.11
no.4
/
pp.141-153
/
2023
In the global context, particularly in Christian nations, Christmas is considered a culturally and ethically significant time. In this study, we examine Charles Dickens' novel, "A Christmas Carol," and the celebration of Christmas in Korea. We explore the values of Christmas in Korea derived from the significance and importance of this novel. These values include repentance, empathy, compassion, and the importance of humanity. Korean Christmas is regarded as a time for practicing these values, bearing a message akin to the transformation of characters like Scrooge. Furthermore, "A Christmas Carol" conveys a message of improvement and change over time, emphasizing change and growth in Korean Christmas. People reflect on their past, correct their mistakes, nurture hope for the future, and experience personal growth and transformation. Additionally, the novel raises awareness of social injustice and inequality, offering alternatives. In Korean society, Christmas encourages the willingness to care for and help others, facilitating discussions and understanding of societal issues. For these reasons, "A Christmas Carol" is considered a culturally and ethically significant time in Korean Christmas, and the two are intertwined in various aspects. This study explores the interaction between cultural change and ethical teachings by 'A Christmas Carol' and investigates the impact of this work on Christmas culture and social change. It serves as the basis for emphasizing moral principles and humanity during the Christmas season, and this research provides suggestions for future research directions, aiming to deepen the understanding of Dickens' work and the importance of "A Christmas Carol." Through these efforts, it is expected that valuable insights into the connection between Christmas culture and moral messages will be gained. In this study, we will delve into the enduring appeal and cultural significance of "A Christmas Carol," discussing how this novel has evolved into a beloved holiday tradition and a true symbol of Christmas. We will also examine the adaptation of this novel into various media and its influence on holiday season celebrations. Insights into the impact of this novel on Korean society and its continued significance in modern times will be provided, suggesting a direction for a healthier and more desirable path for Korean society.
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