• 제목/요약/키워드: two-step growth

검색결과 294건 처리시간 0.022초

Salmonella sp. 의 신속한 동정을 위한 증진배양의 개선에 관한 연구

  • 김기태;김태우;육순학;이영호;백운화
    • 한국미생물·생명공학회지
    • /
    • 제24권6호
    • /
    • pp.647-651
    • /
    • 1996
  • The development of an enrichment method for the rapid and effective identification of Salmonella spp. in sewage or food was studied. As a growth factor for Salmonella, 10 mM cyclic adenosine monophosphate (cAMP) in trypticase soy broth with 0.6% yeast extract (TSBYE) increased cell number five-folds and 0.6% yeast extract in selenite broth increased cell number ten-folds of control. Bile salts in selenite broth was tested for the selection of S. enteritidis in a mixture with Staphylococcus aureus, Pseudomonas aeruginosa, Lactobacillus plantarum and Escherichia coli. The latter four strains were effectively inhibited at 0.1% bile salt. A two-step culture method was used to enrich Salmonella spp.; a primary-enrichment and secondary- enrichment culture. At a primary-enrichment step, selenite broth with 0.6% yeast extract and 10 mM cAMP was used, and at a secondary-enrichment step, 0.1% bile salt was additionally used. Culture times of a primary- enrichment and a secondary-enrichment step were 8 hr and 6 hr, respectively. In this procedure, cell number increased from 10$^{0.3}$ to 10$^{8.5}$ with inhibition of other strains within 14 hr. In the case of an initial cell concentrarion as low as 10$^{-2}$ cfu/ml, a cell number increased to 10$^{7}$ cfu/ml by using a 10 hr primary-enrichment and 6 hr secondary-enrichment procedure.

  • PDF

아공정 Al-Si 합금에서 Si 함량과 냉각속도에 따른 제이차수지상간격의 변화 (Change of Secondary Dendrite Arm Spacing of Hypoeutectic Al-Si Alloys according to Si Content and Cooling Rate)

  • 박경섭;김희수
    • 한국주조공학회지
    • /
    • 제37권4호
    • /
    • pp.108-114
    • /
    • 2017
  • In this study, we investigated the effect of the Si content on the secondary dendrite arm spacing (SDAS) of hypoeutectic Al-Si binary alloys in the range of 4~10 wt% Si. Cooling curves were measured during the solidification of the alloy cast in a step-wise mold. We compared two kinds of solidification time: the first is the total solidification time for both dendritic and eutectic growth, and the second is the solidification time for only dendritic growth. The proportional constant in the relationship between SDAS and cooling rate was estimated, as this constant represents the stability of the cast microstructure. The proportional constant decreased with the Si contents from 4 wt% to 8 wt%, and it remains relatively uniform with up to 10 wt% of Si.

The Effect of Social Entrepreneurship in a Startup Company on Corporate Social Responsibility

  • JUNG, Kum-Jong;JEON, Byung-Hoon
    • 동아시아경상학회지
    • /
    • 제10권1호
    • /
    • pp.47-57
    • /
    • 2022
  • Purpose - Overall social entrepreneurship has a positive effect on the organization's C.S.R. and overall growth. This study aims to identify the effects of social entrepreneurship in startup companies on corporate social responsibility by identifying gaps in the literature and providing feasible solutions to the gaps. Research design, Data, and methodology - The qualitative content analysis that was conducted by this research takes the form of two research designs. The first step to conducting a conceptual content analysis is to choose the level of analysis, specifically words, phrases, word sense and the second step is the relational content analysis by choosing the concept to be examined, only that the analysis entails examining the relationships between concepts Result - According to the investigation of numerous previous literature review, the current authors found out total six solutions and the application of suggested solutions indicated that the use of innovative models, startup organizations can gain a competitive edge against dominant competitors in their industry of operations, Conclusion - Finally, the conclusion of this research indicates through the use of innovative solution models, startup organizations can gain a competitive edge against dominant competitors in their industry of operations and startup companies may range from an increase in reputation to growth in profitability and entrepreneurs' satisfaction.

일부 서울지역 남.여 고교생의 체격과 영양상태에 관한 유사종단적 연구 (A Semi-longitudinal Study on Physiques and Nutritional Status of Korean Youth in a Seoul Special City)

  • 윤태영
    • Journal of Preventive Medicine and Public Health
    • /
    • 제20권1호
    • /
    • pp.97-113
    • /
    • 1987
  • This study was carried out to know physical growth and development, physical and nutritional indices and body fat weight and so forth by semi-longitudinal research method to measure body height, body weight, chest girth and sitting height of 260 of general high school and 306 of vocational high school 3rd grade students who are living in Seoul and born from 1966 March 1st to 1967 Feb.28th. The results are as follows: 1) Physical growth and development Growth in terms of body height showed one step straight linear development, andthat of body weight showed two step straight linear development in each section in high school. The age of cross over between two sexes of general high school students was between 10.6 to 12. 3 years in body height, between 10.8 to 13 years in body weight, between 11.2 to 14.6 years in chest girth and between 10 to 13 years in sitting height. The age of cross over between two sexes of vocational high school students was between 10.5 to 12.5 years in body height, between 10.5 to 12.5 years in body weight, between 10.5 to 12.5 years in chest girth and between 10.5 to 12.5 years in sitting height. In this periods, female group was superior to male group and after that male group was superior to female group again. The growth of vocational school students was superior to that of general school students in both sexes in terms of body height and body weight significantly. 2) Physical growth and nutritional indices In all cases of relative body weight, relative chest girth and relative sitting height, it was found to be increasing thereafter with advancing ages. In cases of $R{\"{o}}hrer$ index and Kaup index, it was found to be reaching to normal state thereafter with advancing ages. In each case of Vervaeck and Pelidisi index, it was found to be increasing and reaching to normal state thereafter with advancing ages. 3) Total body fat by vital measuring method Average values of body surface area, body volume and body density are measured indirectly by using the body height and body weight as Table 12, 13 and 14. The rate of body fat weight of general high school students was from minimum $11.96{\pm}3.53%(3.33{\pm}1.10kg$) to maximum $18.25{\pm}6.46%(9.08{\pm}2.01kg$) in male and from $25.88{\pm}3.62%(7.96{\pm}0.78kg$) to $43.00{\pm}7.22%(12.91{\pm}1.21kg$) in female. The rate of body fat weight of vocational high school students was from minimum $11.20{\pm}2.88%(3.32{\pm}1.13kg$) to maximum $17.16{\pm}5.88(10.83{\pm}3.16kg$) in male and from minimum $25.11{\pm}2.26%(7.91{\pm}0.89kg$) to maximum $42.16{\pm}7.96%(13.22{\pm}1.75kg$) in female.

  • PDF

마그네시아의 치밀화 및 입자성장에 미치는 첨가물의 영향 (Effect of Additives on Densification and Grain Growth of Magnesia)

  • 이해원;김환
    • 한국세라믹학회지
    • /
    • 제19권2호
    • /
    • pp.127-132
    • /
    • 1982
  • This experiment has been carried out for the purpose of investigating the effect of additives on densification and grain growth in magnesium oxide by a two-step process; hot pressing and heat treating. MgO powder has been obtained by calcining extra reagent grade MgCO3 at 90$0^{\circ}C$ for 30 minutes, and additives have been added to $MgCO_3$ in the form of soluble salts-Al$(NO_3)_3$$. $9H_2O$ and $Cr(NO_3)_3$.9H_2O$. The hot pressing has been carried out with changes of soaking time at 125$0^{\circ}C$ under the pressure of 250kg/$\textrm{cm}^2$, and the heat treating also at same temperature. The initial particle size of MgO measured by particle size analyzer was 0.86 microns. Densification rate obeyed the equation D=K lnt + C, and grain growth rate obeyed the equation G-G0=kt1/2. It was vaporization of some $Cr_2O_3$ and formation of solid solution that had an influence on desification of MgO containing $Cr_2O_3$. Activation energy for grain growth of pure MgO was 62.4 kcal/mole, therefore grain growth was supposed to be diffusioncontrolled process. But after heat treatmeat, excess additives were expected to slow down the grain growth by the formation of second phase or the solute atoms at grainboundary.

  • PDF

도시성장에 따른 토지이용패턴의 시공간적 영향 평가 (The Spatiotemporal Impact of Urban Growth based on Landuse Pattern)

  • 이동근;최혜영;오규식
    • 환경영향평가
    • /
    • 제18권3호
    • /
    • pp.161-170
    • /
    • 2009
  • As urban growth continues, the earth ecosystem is increasingly dependent on the patterns of urban growth. The impact intensity from urban growth is expected to change predictably with distance from the urban center. However we can't fully understand yet how urban development pattern affects urban ecosystem. In researches about urban ecosystem, it is important to relate the spatial pattern of urbanization to ecological processes. So we used gradient analysis with time data; 1980's, 1990's and 2000's. We attempted to quantify the urban spatiotemporal impacts in Daejeon-city and Cheonan-city, Korea, along a 75km long and 3km wide transect. Through the results, we found the impacts range of urbanization with urban development process of two cities. When the urban growth was concentrated on in both cities, the impacts intensity and range were much stronger and wider. As a result, in urban planning or green space planning, we have to consider suitable urban development forms with surrounding areas, and make legal clauses which limits landuse change. This quantifying the urban gradient is an important step in understanding urban ecology.

중간층 Ti 두께에 따른 CoSi2의 에피텍시 성장 (Effect of Ti Interlayer Thickness on Epitaxial Growth of Cobalt Silicides)

  • 정성희;송오성
    • 한국재료학회지
    • /
    • 제13권2호
    • /
    • pp.88-93
    • /
    • 2003
  • Co/Ti bilayer structure in Co salicide process helps to the improvement of device speed by lowering contact resistance due to the epitaxial growth of $CoSi_2$layers. We investigated the epitaxial growth and interfacial mass transport of $CoSi_2$layers formed from $150 \AA$-Co/Ti structure with two step rapid thermal annealing (RTA). The thicknesses of Ti layers were varied from 20 $\AA$ to 100 $\AA$. After we confirmed the appropriate deposition of Ti film even below $100\AA$-thick, we investigated the cross sectional microstructure, surface roughness, eptiaxial growth, and mass transportation of$ CoSi_2$films formed from various Ti thickness with a cross sectional transmission electron microscopy XTEM), scanning probe microscopy (SPM), X-ray diffractometery (XRD), and Auger electron depth profiling, respectively. We found that all Ti interlayer led to$ CoSi_2$epitaxial growth, while $20 \AA$-thick Ti caused imperfect epitaxy. Ti interlayer also caused Co-Ti-Si compounds on top of $CoSi_2$, which were very hard to remove selectively. Our result implied that we need to employ appropriate Ti thickness to enhance the epitaxial growth as well as to lessen Co-Ti-Si compound formation.

인터넷 구매결정과정에서의 관여도의 조절효과에 관한 연구 (Examining the Moderating Effect of Involvement in the Internet Purchase Decision Process)

  • 곽기영;지소영
    • Asia pacific journal of information systems
    • /
    • 제18권2호
    • /
    • pp.15-40
    • /
    • 2008
  • With the explosive growth of the Internet, Internet shopping malls have become recognized as one of the major purchasing channels for consumers, as well as one of the competitive distribution channels for companies that allow them to contact with customers without intermediaries. It has motivated information systems(IS) researchers to examine the factors influencing consumer behavior and the purchase decision process in the context of Internet shopping malls. Despite the extensive research that has been conducted on the purchase decision process of consumers in online shopping malls, the results have demonstrated a need for further understanding of consumer behavior due to the unique features of virtual space and the characteristics of online consumers. Previous studies from marketing and consumer behavior domains have suggested that the concept of involvement plays an important role in explaining consumers' purchase behavior. Despite the critical role of involvement and the explosive growth of e-commerce, little research has examined the role of involvement in the Internet shopping mall context. With this motivation, this study has two research objectives. First, it introduces and tests an theoretical model capable of better explaining consumers' intention to purchase in the Internet shopping mall context. The proposed model extends and integrates existing models on purchase intention by incorporating purchase experience, innovativeness, and perceived self-control as the consumer factors, along with perceived risk, information provision, and perceived price as the Internet shopping mall factors. Second, this study examines how involvement differences may affect consumers' intention to purchase. For this purpose, two factors from involvement theory, involvement type and involvement level, are introduced into the research model as moderating variables. In order to test the proposed model, the overall approach employed was a field study using the structural equation model. We developed our data collection instrument by adopting existing validated questions wherever possible. All question items were measured with a seven-point, Likert-type scale, with anchors ranging from 'strongly disagree' to 'strongly agree.' Two IS researchers reviewed the instrument and checked its face validity. We collected empirical data for this study over a period of two weeks from subjects who had purchase experiences through Internet shopping malls. A total of 473 complete and valid responses were obtained. We carried out data analysis using a two-step methodology with AMOS 4.0. The first step in the data analysis was to establish the convergent and discriminant validity of the constructs. In the second step, we examined the structural model based on the cleansed measurement model. The empirical results partly support the proposed model and identify the moderating effect of involvement differences. Theoretical and practical implications of the study are discussed, along with its limitations.

Deep learning for the classification of cervical maturation degree and pubertal growth spurts: A pilot study

  • Mohammad-Rahimi, Hossein;Motamadian, Saeed Reza;Nadimi, Mohadeseh;Hassanzadeh-Samani, Sahel;Minabi, Mohammad A. S.;Mahmoudinia, Erfan;Lee, Victor Y.;Rohban, Mohammad Hossein
    • 대한치과교정학회지
    • /
    • 제52권2호
    • /
    • pp.112-122
    • /
    • 2022
  • Objective: This study aimed to present and evaluate a new deep learning model for determining cervical vertebral maturation (CVM) degree and growth spurts by analyzing lateral cephalometric radiographs. Methods: The study sample included 890 cephalograms. The images were classified into six cervical stages independently by two orthodontists. The images were also categorized into three degrees on the basis of the growth spurt: pre-pubertal, growth spurt, and post-pubertal. Subsequently, the samples were fed to a transfer learning model implemented using the Python programming language and PyTorch library. In the last step, the test set of cephalograms was randomly coded and provided to two new orthodontists in order to compare their diagnosis to the artificial intelligence (AI) model's performance using weighted kappa and Cohen's kappa statistical analyses. Results: The model's validation and test accuracy for the six-class CVM diagnosis were 62.63% and 61.62%, respectively. Moreover, the model's validation and test accuracy for the three-class classification were 75.76% and 82.83%, respectively. Furthermore, substantial agreements were observed between the two orthodontists as well as one of them and the AI model. Conclusions: The newly developed AI model had reasonable accuracy in detecting the CVM stage and high reliability in detecting the pubertal stage. However, its accuracy was still less than that of human observers. With further improvements in data quality, this model should be able to provide practical assistance to practicing dentists in the future.

CELECOXB (CELEBREX) INHIBITS PHORBOL ESTER-INDUCED COX-2 EXPRESSION AND $PGE_2$ PRODUCTION IN MOUSE SKIN: AP-1 AND C/EBP AS POSSIBLE MOLECULAR TARGETS

  • Chun, Kyung-Soo;Surh, Young-Joon
    • 한국독성학회:학술대회논문집
    • /
    • 한국독성학회 2002년도 Current Trends in Toxicological Sciences
    • /
    • pp.103-104
    • /
    • 2002
  • Cyclooxygenase (COX), an important enzyme involved in mediating the inflammation, catalyzes the rate-limiting step in the formation of prostaglandins from arachidonic acid. There are two isoforms of COX, designated as COX-1 and COX-2. While COX-1 is constitutively expressed in most tissues, COX-2 can be induced transiently by proinflammatory cytokines, endotoxins, growth factors, oncogenes, UV and mitogens.(omitted)

  • PDF