• Journal of Chest Surgery
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• 제48권4호
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• pp.289-293
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• 2015

A 38-year-old male was admitted with symptoms of upper respiratory infection. Despite medical treatment, his symptoms of dyspnea and anxiety became aggravated, and bilateral lung infiltration was noted on radiological imaging studies. His hypoxemia failed to improve even after the application of endotracheal intubation with mechanical ventilator care, and we therefore decided to initiate venovenous extracorporeal membrane oxygenation (VV ECMO) for additional pulmonary support. On his twentieth day of hospitalization, hypotension and desaturation (arterial saturated oxygen <85%) developed, and right ventricular failure was confirmed by two-dimensional echocardiography. Therefore, we changed from VV ECMO to venoarteriovenous (VAV) ECMO, and the patient ultimately recovered. In this case, right ventricular dysfunction and volume overloading were induced by long-term VV ECMO therapy, and we successfully treated these conditions by changing to VAV ECMO.

• 대한한의학회지
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• 제23권4호
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• pp.140-150
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• 2002

Objectives: The water extract of Omija-tang (OMIT) has traditionally been used for treatment of ischemic heart and brain damage in oriental medicine. However, little is known about the mechanism by which the water extract of OMJT rescues cells from these damages. Therefore, this study was designed to investigate the protective mechanisms of OMJT on oxidative stress-induced toxicity in H9c2 cardiomyoblast cells. Methods: Treatments of $H_2O_2$, or $ZnC_{12}$ markedly induced death of H9c2 cardiomyoblast cells in a dose-dependent manner. The characteristics of oxidative stress-induced death of H9c2 showed apparent apoptotic features such as DNA fragmentation. OMJT significantly reduced both ${H_2O_2}-induced$ cell death and chromatin fragmentation. The decrease of B치-XL expression by $H_2O_2$ were inhibited by OMJT. In addition, the increase of Bcl-XS expression was also inhibited by OMJT. In particular, Fas expression, which is generally recognized as cell death-inducing signal by Fas/FasL interaction, was markedly increased by H2O2 in a time-dependent manner. Also, the expression profile of proteins in Chang cells were screened by using two-dimensional (2-D) gel electrophoresis. Among 300 spots resolved in 2-D gels; the comparison of control versus apoptotis cells revealed that signal intensity of 6 spots decreased and 11 spots increased. Results and Conclusions: Taken together, this study suggests that the protective effects of the water extract of OMJT against oxidative damages may be mediated by the modulation of Bcl-XL/S Fas expression.

• 비파괴검사학회지
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• 제19권1호
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• pp.8-15
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• 1999

교류전위차법 (alternating current potential drop : ACPD)을 이용하여 이차원 표면균열을 갖고 있는 강자성체 (ferromagnetic material)와 상자성체 (paramagnetic material)의 모드 I (opening mode) 응력확대계수($K_I$)를 효과적으로 계측하는 방법을 개발하기 위하여 하중에 따른 교류전위차 변화(change in ACPD)에 미치는 자속(magnetic flux)의 영향을 연구하였다. 그리고 하중에 따른 전위차 변화에 미치는 탈자(demagnetization) 및 균열길이의 영향을 연구하였다. 기전력을 많이 유도할 수 있도록 설계된 계측계의 경우 하중에 따른 교류전위차 변화량은 크게 증가하였다. 아울러 교류전위차 변화와 응력확대계수 변화 사이의 관계는 탈자 등의 조치가 없어도 선형적이며, 탈자는 전위차 변화에 거의 영향을 미치지 않았다. 일정 $K_I$ 변화에 의한 전위차 변화량은 균열길이에 의존하지 않고 계측계에 의존한다. 교류전위차법을 이용하여 효과적으로 응력확대계수를 결정하는 방법은 기전력을 많이 유도할 수 있도륵 설계된 계측계를 사용하여 교류전위차 변화를 측정하는 것이다.

• Restorative Dentistry and Endodontics
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• 제22권1호
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• pp.347-357
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• 1997

An accurate working length is an essential factor in the success of endodontic treatment. There are several methods for determining working length; electronic apex locator, tactile sense by clinician, and radiography. Among these methods, the most commonly used method is radiography. But this method requires excessive radiation, long developing time, and many equipments. In additon, it could give an image distortion and two dimensional image. To improve these disadvantages, an intraoral digital radiographic system (Digora$^{(R)}$) which use an imaging plate instead of a film, was developed. The purpose of this investigation was to compare Digora imaging with conventional radiography in determining the working length. Maxillary first or second molars of human dried skull were used. Files were inserted into canals at randomly selected lengths, from 2mm short of the radiographic apex to 2rnm beyond. Radiographs and Digora images(Digora positive and Digora negative) were evaluated to determine the adjustment needed to place the file 0.5mm from the radiographic apex. The results were as follows ; 1. There was no significant difference in accuracy between those evaluated in ${\pm}0.5mm$ and those accurately evaluated in the 3 images. 2. When comparing the accuracy of each image without distinguishing the 3 images, in the group accurately determined within ${\pm}0.5mm$, the mesiobuccal group showed significantly higher accuracy compared to the palatal group(p<0.05).

• 자원환경지질
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• 제29권3호
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• pp.335-343
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• 1996

The dipole-dipol electrical resistivity survey was conducted to investigate the probable contamination of the Han river by leachate from the near-by Nanjido Landfill. The survey line of 3 km was set along the unpaved road toward the Han river. For the convenience of the field work, the survey line was divided into four segments. The complete two-dimensional resistivity section was constructed by connecting the inversion result of each segment. Gravity survey was also carried out along the profile parallel to the resistivity line. Near surface resistivity generally appeared to be of very low value in most part of the survey area and the boundary between the alluvium layer and underlying basement rocks is well discriminated on the resistivity section. These results agree well with those of the preceding Schlumberger depth sounding made at adjacent area by Lee and fun (1995). The variation of thickness of the alluvium layer delineated by gravity anomaly profile also correlates well with the result of the resistivity survey on the qualitative basis. The problem of contamination by leachate from the Nanjido Landfill, where various waste materials have been dumped without any proper treatment facilities, has been remains unsolved yet. Therefore, we present the most probable passages of leachate flow based on the survey results and have briefly discussed about measure for contamination control. Considering the thickness of alluvium and the possible existence of fractured zone, the middle point between 1st and 2nd landfill and the midst of 1st landfill are the most hazardous regions to make leachates flow into the Han river. Since large amounts of leachates are observed from the test wells located on the lines extending from the border between the 1st and 2nd landfill and the middle of the lst landfill, contamination protection barriers are strongly recommended near these regions.

• 대한정형도수물리치료학회지
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• 제9권2호
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• pp.25-45
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• 2003

Sling exercise treatment(S-E-T) is a therapeutic exercise based on scientific studies for the purpose of treating musculoskeletal or neurological disorders thereby improving strength, endurance, and skills for sensory-motor integration. Exercise resistance and intensity can be modified in various ways by changing the length of rope, patient position, therapist's manual resistance, and using elastic rope. The therapist can also progress to successively higher levels of exercise resistance and intensity by changing the position of the hanging point: the subject of this article. In brief, there are three axial components in S-E-T; hanging point, motor axis, and suspension point. The hanging point can be changed in several ways in relation to the joint; axial, superior, inferior, medial, and posterior hanging points. The position of the hanging point affects the amount of load on agonist and antagonist muscles as well as on the range of motion. To create an advanced exercise program, selection of hanging point can be two-dimensional such as superior-lateral or anterior-medial. Therapists, therefore, can freely but carefully select the best hanging point based on the purpose of the exercise and their level of knowledge in S-E-T.

• 대한치과보철학회지
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• 제34권4호
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• pp.850-868
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• 1996

The accuracy and dimensional stability of impression materials are one of the most important factors for successful prosthodontic treatment. The purpose of this study was to evaluate the accuracy of several dental elastomeric impression materials used widely and clinically : Impregum-$F^{(R)},\;Permlastic^{(R)},\;Silascon^{(R)},\;Perfect^{(R)},\;Xantopren^{(R)}$. There have been many studies to evaluate the accuracy of impression materials. But it has not been decided yet, which method was most suitable for the evaluation of the accuracy. In this study, two resin teeth, #15 & 25, were prepared with rounded shoulder margin and 90 degree cavosurface angle. For the polysulfide rubber and polyether, the custom tray was made at least 24 hours prior to impression taking. For the silicone rubber materials, putty/wash impression technique was applied in taking impressions. Marginal openings of the castings on the master dies and prepared resin teeth were measured under stereomicroscope. The results were statistically analyzed and compared between tested impression materials. The results were as follows ; 1. In the overall accuracy of impression materials, polyether was the most accurate one, followed by polysulfide, additional silicone and condensation silicone. 2. On the first model pouring, condensation silicone had the largest discrepancies and there was significant difference compared to the other impression materials. 3. Polysulfide had the least discrepancies in the first model pouring, but showed larger discrepancies in the immediate second pouring than the first pouring. 4. On the immediate second pouring, the discrepancy of polyether was shown to be the smallest, while the largest one was additional silicone. 5. Polyether and polysulfide rubber using custom impression trays showed superior accuracy to silicone rubber, putty/wash impression technique.

• 한국항공우주학회지
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• 제33권9호
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• pp.34-40
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• 2005

본 연구에서는 비정상 유동해석을 위한 CFD 코드의 개발을 위해 대각화 ADI 기법을 적용한 정상 해석기법과 내재적 이중시간 전진기법을 도입하였다. 정상상태 Navier-Stokes 방정식의 Jacobian 행렬은 비점성항에 대해서만 적용하였고 여기에 내재적 인공점성 연산자를 첨가하여 블록 5대각 행렬을 유도하였다. 시간단축을 위해 스칼라 5대각 행렬로 대체하였다. 가상시간에 대한 정상상태기법에 실시간에 대한 미분항이 포함된 새로운 잔류항을 정의하였다. 가상시간에 대해 수렴된 해로부터 실시간 해를 구하고 시간에 대해 적분을 수행하는 내재적 이중시간 전진기법을 이용한 비정상 Navier-Stokes 코드를 개발하였다. 이에 대한 검증으로 정지한 유체속에 진동하는 평판문제, 원기둥 후방의 주기적인 Karman 와류생성, 이중원호 익형주위의 충격파 진동문제등을 수치해석하여 이론치, 실험치, 타연구자의 계산결과와 비교, 분석하였다.

• Nuclear Engineering and Technology
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• 제15권1호
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• pp.33-40
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• 1983

본 논문에서는 Shanks의 수열 전환방법 중 $E_{k}$-전환을 연구하여 $E_1$-전환과 single extrapolation 방법과의 관계를 정립하고 나아가서 중성자 확산 방정식의 반복법에 $E_1$$^2$-전환을 적용하여 double extrapolation 방법을 유도하고 있으며, 이를 CITATION코드에서 적용해 보았다. 이 경우 double extrapolation은 기존의 single extrapolation 방법보다 효과적으로 외부 반복법을 가속시키고 있는데 단, double extrapolation 방법이 일어날 수 있는 조건을 만족시켜 double extrapolation이 일어나는 경우이다. 또 CITATION코드는 내부 반복법에서 'Equipose' 방법이라하여 내부 반복횟수를 1회만 하고 외부 반복법으로 넘어가는 방법이 가장 빠른 것으로 간주하고 program이 되어 있으나, 내부 반복법에서 에너지 군별로 반복횟수를 다르게 줄 경우, 예를 들면 속 중성자속과 열 중성자속을 계산하는 반복과정중 반복횟수를 각각 2번과 1번으로 줄 경우는 기존의 Equipose보다 매우 빠름을 알 수 있다. 단, 이 경우는 에너지 군이 2군일 경우 명확하게 보여주고 있다.

• 미생물학회지
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• 제29권1호
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• pp.49-55
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• 1991

The heat shock responses of Campylobacter jejuni were studied by examination of their survival rates and synthesis of heat shocd proteins. When C. jejuni cells were treated at the sublethal temperatures of 48.deg.C for 30 minutes, most of the cells maintained their viabilities and synthesized the heat shock proteins of 90, 73, and 66 kD in molecular weight. By the method of two-dimensional electrophoresis, the heat shock proteins of C. jejuni were identified to be Hsp90, Hsp73, and Hsp66. During the heat shock at 48.deg.C, the heat shock proteins were induced from about 5 minutes after the heat shock treatment. Their synthesis was continued upto 30 minutes, but remarkably retarded after 50 minutes. When C. jejune cells were heat shocked at 51.deg.C for 30 minutes, the survival rates of the cells were decreased by about $10^{3}$ fold and synthesis of heat shock proteins and normal proteins was also generally retarded. The cells exposed to 55.deg.C for 30 minutes died off by more than $10^{5}$ cells and the new protein synthesis was not observed. But when C. jejuni cells were heat-shocked at the sublethal temperature of 48.deg.C for 15 to 20 minutes and then were exposed at the lethal temperature of 55.deg.C for 30 minutes, their viabilities were higher than those exposed at 55.deg.C for 30 minutes without pre-heat shock at 48.deg.C. Therefore, the heat shock proteins synthesized at the sublethal temperature of 48.deg.C in C. jejuni were thought to be responsible for thermotolerance. However, when C. jejuni cells heat-shocked at various ranges of sublethal and lethal temperatures were placed back to the optimum temperature of 42.deg.C, the multiplication patterns of the cells pretreated at different temperatures were not much different each other.