• Title/Summary/Keyword: two-dimensional treatment

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Right Heart Failure during Veno-Venous Extracorporeal Membrane Oxygenation for H1N1 Induced Acute Respiratory Distress Syndrome: Case Report and Literature Review

  • Lee, Seung-Hun;Jung, Jae-Seung;Chung, Jae-Ho;Lee, Kwang-Hyung;Kim, Hee-Jung;Son, Ho-Sung;Sun, Kyung
    • Journal of Chest Surgery
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    • v.48 no.4
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    • pp.289-293
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    • 2015
  • A 38-year-old male was admitted with symptoms of upper respiratory infection. Despite medical treatment, his symptoms of dyspnea and anxiety became aggravated, and bilateral lung infiltration was noted on radiological imaging studies. His hypoxemia failed to improve even after the application of endotracheal intubation with mechanical ventilator care, and we therefore decided to initiate venovenous extracorporeal membrane oxygenation (VV ECMO) for additional pulmonary support. On his twentieth day of hospitalization, hypotension and desaturation (arterial saturated oxygen <85%) developed, and right ventricular failure was confirmed by two-dimensional echocardiography. Therefore, we changed from VV ECMO to venoarteriovenous (VAV) ECMO, and the patient ultimately recovered. In this case, right ventricular dysfunction and volume overloading were induced by long-term VV ECMO therapy, and we successfully treated these conditions by changing to VAV ECMO.

Effects & Mechanism of Omija-tang on Oxidative Stress-Induced Death of H9c2 Cardiomyoblast Cell (심근세포의 산화적 손상에 대한 오미자탕의 효과 및 작용기전 연구)

  • 황보연;양경석;이상관;이기상;문병순;신선호
    • The Journal of Korean Medicine
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    • v.23 no.4
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    • pp.140-150
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    • 2002
  • Objectives: The water extract of Omija-tang (OMIT) has traditionally been used for treatment of ischemic heart and brain damage in oriental medicine. However, little is known about the mechanism by which the water extract of OMJT rescues cells from these damages. Therefore, this study was designed to investigate the protective mechanisms of OMJT on oxidative stress-induced toxicity in H9c2 cardiomyoblast cells. Methods: Treatments of $H_2O_2$, or $ZnC_{12}$ markedly induced death of H9c2 cardiomyoblast cells in a dose-dependent manner. The characteristics of oxidative stress-induced death of H9c2 showed apparent apoptotic features such as DNA fragmentation. OMJT significantly reduced both ${H_2O_2}-induced$ cell death and chromatin fragmentation. The decrease of B치-XL expression by $H_2O_2$ were inhibited by OMJT. In addition, the increase of Bcl-XS expression was also inhibited by OMJT. In particular, Fas expression, which is generally recognized as cell death-inducing signal by Fas/FasL interaction, was markedly increased by H2O2 in a time-dependent manner. Also, the expression profile of proteins in Chang cells were screened by using two-dimensional (2-D) gel electrophoresis. Among 300 spots resolved in 2-D gels; the comparison of control versus apoptotis cells revealed that signal intensity of 6 spots decreased and 11 spots increased. Results and Conclusions: Taken together, this study suggests that the protective effects of the water extract of OMJT against oxidative damages may be mediated by the modulation of Bcl-XL/S Fas expression.

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Effective Way of Measuring $K_I$ by Means of ACPD Technique (교류전위차법을 이용한 효과적인 응력확대계수의 측정 방법)

  • Lee, Jeong-Hee
    • Journal of the Korean Society for Nondestructive Testing
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    • v.19 no.1
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    • pp.8-15
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    • 1999
  • In order to develop an effective way of measuring the mode I stress intensity factor, $K_I$, by the technique based on the alternating current potential drop (ACPD), the effect of the magnetic flux in the air on the change in potential drop due to load for both ferromagnetic and paramagnetic materials containing a two-dimensional surface crack was investigated. Additionally the effects of the demagnetization and the crack length on the change in potential drop were examined. In the case that the measuring system was designed to induce a large amount of electromotive force, the amount of the change in potential drop due to load was shown to increase largely Also the relationship between the change in potential drop and that in $K_I$ was indicated to be linear without any treatment and it was shown that the demagnetization had almost no effect on the change in potential drop. The change in potential drop did not depend on the crack length but on the measuring system. For the application of the ACPD technique to determine $K_I$.

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THE ACCURACY OF DIGORA SYSTEM, AN INDIRECT DIGITAL RADIOGRAPHIC SYSTEM, IN DETERMINING THE WORKING LENGTH (근관장 측정시 구내 디지털 방사선 시스템인 Digora System의 정확도에 관한 연구)

  • Han, Sang-Wook;Hang, Chan-Ui;Cho, Yong-Bum
    • Restorative Dentistry and Endodontics
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    • v.22 no.1
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    • pp.347-357
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    • 1997
  • An accurate working length is an essential factor in the success of endodontic treatment. There are several methods for determining working length; electronic apex locator, tactile sense by clinician, and radiography. Among these methods, the most commonly used method is radiography. But this method requires excessive radiation, long developing time, and many equipments. In additon, it could give an image distortion and two dimensional image. To improve these disadvantages, an intraoral digital radiographic system (Digora$^{(R)}$) which use an imaging plate instead of a film, was developed. The purpose of this investigation was to compare Digora imaging with conventional radiography in determining the working length. Maxillary first or second molars of human dried skull were used. Files were inserted into canals at randomly selected lengths, from 2mm short of the radiographic apex to 2rnm beyond. Radiographs and Digora images(Digora positive and Digora negative) were evaluated to determine the adjustment needed to place the file 0.5mm from the radiographic apex. The results were as follows ; 1. There was no significant difference in accuracy between those evaluated in ${\pm}0.5mm$ and those accurately evaluated in the 3 images. 2. When comparing the accuracy of each image without distinguishing the 3 images, in the group accurately determined within ${\pm}0.5mm$, the mesiobuccal group showed significantly higher accuracy compared to the palatal group(p<0.05).

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Dipole-Dipole Resistivity Survey on the Side of Han River near Nanjido Landfill (난지도에 인접한 한강변에서의 쌍극자-쌍극자 전기탐사)

  • Lee, Kiehwa;Kwon, Byung-Doo;Oh, Seok-Hoon;Kim, Cha-Seop
    • Economic and Environmental Geology
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    • v.29 no.3
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    • pp.335-343
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    • 1996
  • The dipole-dipol electrical resistivity survey was conducted to investigate the probable contamination of the Han river by leachate from the near-by Nanjido Landfill. The survey line of 3 km was set along the unpaved road toward the Han river. For the convenience of the field work, the survey line was divided into four segments. The complete two-dimensional resistivity section was constructed by connecting the inversion result of each segment. Gravity survey was also carried out along the profile parallel to the resistivity line. Near surface resistivity generally appeared to be of very low value in most part of the survey area and the boundary between the alluvium layer and underlying basement rocks is well discriminated on the resistivity section. These results agree well with those of the preceding Schlumberger depth sounding made at adjacent area by Lee and fun (1995). The variation of thickness of the alluvium layer delineated by gravity anomaly profile also correlates well with the result of the resistivity survey on the qualitative basis. The problem of contamination by leachate from the Nanjido Landfill, where various waste materials have been dumped without any proper treatment facilities, has been remains unsolved yet. Therefore, we present the most probable passages of leachate flow based on the survey results and have briefly discussed about measure for contamination control. Considering the thickness of alluvium and the possible existence of fractured zone, the middle point between 1st and 2nd landfill and the midst of 1st landfill are the most hazardous regions to make leachates flow into the Han river. Since large amounts of leachates are observed from the test wells located on the lines extending from the border between the 1st and 2nd landfill and the middle of the lst landfill, contamination protection barriers are strongly recommended near these regions.

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A Clinical Application with the Principle of Hanging Point In the Sling Exercise Therapy (슬링운동치료에서 Hanging Point의 원리와 임상적 적용)

  • Kim, Suhn-Yeop;Kim, Taek-Yean;Park, Sung-Jin
    • The Journal of Korean Academy of Orthopedic Manual Physical Therapy
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    • v.9 no.2
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    • pp.25-45
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    • 2003
  • Sling exercise treatment(S-E-T) is a therapeutic exercise based on scientific studies for the purpose of treating musculoskeletal or neurological disorders thereby improving strength, endurance, and skills for sensory-motor integration. Exercise resistance and intensity can be modified in various ways by changing the length of rope, patient position, therapist's manual resistance, and using elastic rope. The therapist can also progress to successively higher levels of exercise resistance and intensity by changing the position of the hanging point: the subject of this article. In brief, there are three axial components in S-E-T; hanging point, motor axis, and suspension point. The hanging point can be changed in several ways in relation to the joint; axial, superior, inferior, medial, and posterior hanging points. The position of the hanging point affects the amount of load on agonist and antagonist muscles as well as on the range of motion. To create an advanced exercise program, selection of hanging point can be two-dimensional such as superior-lateral or anterior-medial. Therapists, therefore, can freely but carefully select the best hanging point based on the purpose of the exercise and their level of knowledge in S-E-T.

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A STUDY ON THE ACCURACY OF SEVERAL DENTAL ELASTOMERIC IMPRESSION MATERIALS (수종의 치과용 탄성인재의 정확도에 관한 연구)

  • Choi, Myoung-Soo;Lim, Ju-Hwan;Cho, In-Ho
    • The Journal of Korean Academy of Prosthodontics
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    • v.34 no.4
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    • pp.850-868
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    • 1996
  • The accuracy and dimensional stability of impression materials are one of the most important factors for successful prosthodontic treatment. The purpose of this study was to evaluate the accuracy of several dental elastomeric impression materials used widely and clinically : Impregum-$F^{(R)},\;Permlastic^{(R)},\;Silascon^{(R)},\;Perfect^{(R)},\;Xantopren^{(R)}$. There have been many studies to evaluate the accuracy of impression materials. But it has not been decided yet, which method was most suitable for the evaluation of the accuracy. In this study, two resin teeth, #15 & 25, were prepared with rounded shoulder margin and 90 degree cavosurface angle. For the polysulfide rubber and polyether, the custom tray was made at least 24 hours prior to impression taking. For the silicone rubber materials, putty/wash impression technique was applied in taking impressions. Marginal openings of the castings on the master dies and prepared resin teeth were measured under stereomicroscope. The results were statistically analyzed and compared between tested impression materials. The results were as follows ; 1. In the overall accuracy of impression materials, polyether was the most accurate one, followed by polysulfide, additional silicone and condensation silicone. 2. On the first model pouring, condensation silicone had the largest discrepancies and there was significant difference compared to the other impression materials. 3. Polysulfide had the least discrepancies in the first model pouring, but showed larger discrepancies in the immediate second pouring than the first pouring. 4. On the immediate second pouring, the discrepancy of polyether was shown to be the smallest, while the largest one was additional silicone. 5. Polyether and polysulfide rubber using custom impression trays showed superior accuracy to silicone rubber, putty/wash impression technique.

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Development of An Unsteady Navier-Stokes Solver using Implicit Dual Time Stepping Method and DADI Scheme (내재적 이중시간 전진기법과 DADI 기법을 이용한 비정상 Navier-Stokes 코드개발)

  • Lee, Eun-Seok
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.33 no.9
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    • pp.34-40
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    • 2005
  • In present study, a two dimensional unsteady Navier-Stokes solver has been developed using the Diagonalized ADI (DADI) method and implicit dual time stepping method. The jacobian matrices in steady state Navier-Stokes equations are introduced from inviscid flux terms. The implicit treatment of artificial dissipation terms results in a block penta-diagonal matrix system and it becomes a scalar penta-diagonal matrix by diagonalization. In steady state equations about fictitious time, a new residual including a real time derivative term is introduced. From a converged solution about fictitious time, a real time unsteady solution can be obtained, which is called 'implicit dual time stepping method'. For code validation, an oscillating flat plate, a regular Karman vortices past a circular cylinder and shock buffeting around a bicircular airfoil problems are numerically solved. And they are compared with a theoretical solution, experiments and other researcher's computations.

A Study of Iteration Method for 2-Dimensional 2-Group Diffusion Problems (2차원 2군 확산 문제의 반복법에 대한 고찰)

  • Jong Hwa Chang;Kil Yoo Kim;Chang Hyun Chung
    • Nuclear Engineering and Technology
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    • v.15 no.1
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    • pp.33-40
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    • 1983
  • It is shown that the Shanks sequence $E_{k}$-transformation and the conventional extrapolation method are theoretically related. The $E_1$$^2$-transformation method is then applied for the multigroup diffusion problems. The diffusion code, CITATION, is modified for this study and the computing time is compared for each iteration tactics. The Equipose method, in which only sing1e inner iteration for each energy group is carried for an outer iteration, has been known as the fastest iteration method. However, in the case of 3-group problems, the proposed method, in which the number of inner iteration for the fast and thermal group is 2 and 1 respectively, gives better convergency than the Equipose method by about 12%. The double extrapolation method results in faster computing time than the single extrapolation method without computing storage problem. It is, however, to note that this method is verified only for a two-group treatment.t.

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Synthesis and thermotolerance of heat shock proteins in campylobacter jejuni (Campylobacter jejuni에서 고온충격 단백질의 합성과 내열성)

  • 김치경;김현옥;이길재
    • Korean Journal of Microbiology
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    • v.29 no.1
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    • pp.49-55
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    • 1991
  • The heat shock responses of Campylobacter jejuni were studied by examination of their survival rates and synthesis of heat shocd proteins. When C. jejuni cells were treated at the sublethal temperatures of 48.deg.C for 30 minutes, most of the cells maintained their viabilities and synthesized the heat shock proteins of 90, 73, and 66 kD in molecular weight. By the method of two-dimensional electrophoresis, the heat shock proteins of C. jejuni were identified to be Hsp90, Hsp73, and Hsp66. During the heat shock at 48.deg.C, the heat shock proteins were induced from about 5 minutes after the heat shock treatment. Their synthesis was continued upto 30 minutes, but remarkably retarded after 50 minutes. When C. jejune cells were heat shocked at 51.deg.C for 30 minutes, the survival rates of the cells were decreased by about $10^{3}$ fold and synthesis of heat shock proteins and normal proteins was also generally retarded. The cells exposed to 55.deg.C for 30 minutes died off by more than $10^{5}$ cells and the new protein synthesis was not observed. But when C. jejuni cells were heat-shocked at the sublethal temperature of 48.deg.C for 15 to 20 minutes and then were exposed at the lethal temperature of 55.deg.C for 30 minutes, their viabilities were higher than those exposed at 55.deg.C for 30 minutes without pre-heat shock at 48.deg.C. Therefore, the heat shock proteins synthesized at the sublethal temperature of 48.deg.C in C. jejuni were thought to be responsible for thermotolerance. However, when C. jejuni cells heat-shocked at various ranges of sublethal and lethal temperatures were placed back to the optimum temperature of 42.deg.C, the multiplication patterns of the cells pretreated at different temperatures were not much different each other.

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