• Journal of Applied Biological Chemistry
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• 제61권4호
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• pp.357-365
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• 2018

된장의 최적 섭취 기간을 판단하기 위해 원료 대두로부터 3년 동안 발효 숙성 하면서 6개월 단위로 시료를 채취하여 분석하였다. 이화학적 분석, 항산화력과 관능 검사를 주성분분석과 k-평균 군집 분석하여 종합적인 품질 특성을 평가하였다. 된장의 품질 특성은 PCA에 의해 1년 간격으로 큰 변화가 확인되었고, 군집 분석에 의해 숙성 기간에 따라 각각 cluster 1, 2, 3의 군집으로 분류되었다. 건강기능성과 관련된 항산화력으로 총 페놀함량, SOD 유사활성, DPPH 라디칼 소거 능력은 cluster 3에서 높았다. Cluster 3에서는 맛과 관련된 관능 평가 항목과 유리아미노산, 유기산 등도 높게 나타났다. 기호도 평가도 cluster 3에서 높게 나타났고 기호도에 가장 큰 영향을 준 관능 항목 요인은 감칠맛과 갈색이었다. 따라서 된장은 숙성 12개월 이후부터 섭취 가능하지만 된장의 맛과 건강 기능적 측면을 동시에 고려한다면 숙성 30개월 이후가 된장의 최적 섭취 시기라고 할 수 있다.

• 한국산림과학회지
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• 제98권3호
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• pp.284-289
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• 2009

이 논문은 VAR 모형과 계량경제모형으로 섬유판 수요를 추정하고 예측정확성을 비교하였으며, VAR 모형을 이용하여 섬유판 수요의 분산분해와 충격반응을 분석하고, 섬유판 수요를 예측하였다. VAR모형은 소비량, 자체가격, 건설업총생산의 시차변수와 더미변수로 구성되어 있고, 계량경제모형은 자체가격, 비목재가격, 건설업총생산, 더미변수로 구성되어 있다. 더미변수는 1990년대 말에 발생한 구제금융의 영향을 반영하였다. 결과에 의하면 섬유판 수요예측은 VAR모형이 계량경제모형보다 더 효율적이다. VAR모형을 이용하여 섬유판 수요의 분산을 분해한 결과에 의하면 섬유판 최종소비처의 산출수준을 나타내는 건설업총생산의 변화가 약 12개월 후에 섬유판 수요변화의 약 50%를 설명하고, 자체가격의 변화가 약 30%를 설명하는 것으로 나타났다. 즉 건설업총생산이 자체가격보다 섬유판 수요에 더 큰 영향을 미친다. 한편 건설업총생산의 충격에 대한 섬유판 수요의 반응은 12개월 동안 서서히 감소하는 반면에 자체가격의 충격에 대한 반응은 6개월이 지나면 거의 사라진다. 즉 건설업총생산이 자체가격보다 섬유판 수요에 더 오래 영향을 미친다. VAR모형을 이용하여 예측한 섬유판의 수요는 건설투자의 증가로 인하여 연평균 약 1.4%씩 증가하여 2010년에 약 220만$m^3$, 2015년에 약 240만$m^3$가 될 것으로 예상된다.

• 한국안광학회지
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• 제18권1호
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• pp.75-84
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• 2013

목적: 연령에 따라 역기하콘택트렌즈(reverse geometry contact lens), MC렌즈(myopia control lens)를 착용 한 후 근시진행억제 효과에 대한 굴절교정값의 변화를 단초점렌즈(single vision lens)와 비교해 알아보고자 한다. 방법: 6세에서 15세 사이의 아동에게 역기하콘택트렌즈 57안, MC렌즈 56안, 단초점렌즈 78안을 각각 착용시킨 후 연령에 따라 Group 1은 10세 이하, Group 2는 11세에서 15세 이하, Group 3은 연구 대상을 모두 포함하여 3그룹으로 나눴다. 이를 바탕으로 12개월 이하, 13~24개월, 25~36개월 까지 굴절교정값의 변화를 통한 근시 진행 억제 효과를 알아보고 통계적 유의성을 검증하고자 하였다. 결과: 착용기간에 따른 굴절교정값의 변화는 Group 3에서 12개월 이하에서는 역기하콘택트렌즈를 착용한 아동에서 변화가 없었고, MC렌즈는 $-0.36{\pm}0.10$ D, 단초점렌즈는 $-0.67{\pm}0.52$ D가 유의하게 변화되었다(P<0.05). 13~24개월에서 역기하콘택트렌즈는 $0.18{\pm}0.49$ D, MC렌즈는 $0.60{\pm}0.42$ D, 단 초점렌즈는 $1.37{\pm}0.72$ D로 유의(P<0.05)하게 변화되었다. 25~36개월에서 역기하콘택트렌즈는 $0.29{\pm}0.61$ D, MC렌즈는 $0.93{\pm}0.57$ D, 단초점렌즈는 $1.72{\pm}0.78$ D로 유의(P<0.05)하게 변화되었다. Group 1에서는 36개월 까지 역기 하콘택트렌즈는 $0.29{\pm}0.73$ D로 MC렌즈는 $1.07{\pm}0.59$ D로 단초점 렌즈는 $1.75{\pm}0.74$ D로 유의(P<0.05)하게 증가하였으며 Group 2에서는 36개월 까지 역기하콘택트렌즈는 $0.28{\pm}0.42$ D로 MC렌즈는 $0.75{\pm}0.49$ D로 단초점 렌즈는 $1.70{\pm}0.84$ D로 유의(P<0.05)하게 증가하여 굴절교정값의 변화는 10세 이하가 11세 이상보다 유의(P<0.05)하게 큰 것으로 나타났다. 결론: 본 연구 결과 12개월 이하의 착용시 역기하콘택트렌즈는 모든 연령에서 굴절교정값의 변화가 없었고, MC렌즈는 모든 연령에서 단초점렌즈보다 더 낮은 시력변화폭을 나타내 근시진행의 억제효과가 있으며, 13~36개월 착용시 역기하콘택트렌즈와 MC렌즈는 모든 연령에서 단초점렌즈보다 낮은 시력변화를 보여 근시진행의 억제효과가 있는 것으로 사료된다.

• Journal of Korean Neurosurgical Society
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• 제40권3호
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• pp.175-179
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• 2006

Objective : The surgical outcome of anterior lumbar interbody fusion[ALlF] with pedicle screw fixation for elderly isthmic spondylolisthesis was analyzed. Methods : Consecutive nineteen elderly patients [aged 65 years or more] with isthmic spondylolisthesis [Grade I or II] who underwent single level ALIF with pedicle screw fixation in 2002 were analyzed. Using clinical chart and mailed questionnaires, preoperative and postoperative Visual Analogue Scale[VAS] of back and leg pain and postopertive Macnab criteria were evaluated. Results : The mean age at the time of operation was 68.4 years [range 65 to 78 years]. Twelve patients underwent ALIF with percutaneous pedicle screw fixation. Seven patients underwent ALIF followed by posterior decompression and pedicle screw fixation. The postoperative complication rate was 10.5% [wound dehiscence in 1 patient and incisional hernia in 1 patient]. There was no postoperative major morbidity or mortality. At a mean follow-up duration of 30.7 months [range 25 to 35 months], 93.3% [14/15] of the patients showed excellent or good outcomes in terms of Macnab criteria. The mean VAS scores of back pain and leg pain significantly decreased after surgery. Conclusion : ALIF with pedicle screw fixation yielded favorable results for elderly isthmic spondylolisthesis in selected cases.

• Journal of Chest Surgery
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• 제48권6호
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• pp.447-451
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• 2015

This report describes the case of a 57-year-old man with an anterior mediastinal tumor. Four years previously, he underwent laparoscopic anterior resection for sigmoid colon cancer. Thirty months after that procedure, bilateral pulmonary metastasectomy was performed. Twelve months later, follow-up computed tomography revealed a 1-cm pulmonary nodule on the upper lobe of the right lung and a solid mass on the anterior mediastinum, and the patient was also observed to have an elevated serum carcinoembryonic antigen (CEA) level. Repeated pulmonary nodule resection and total thymectomy were performed. Immunohistochemical staining of the anterior mediastinal tumor revealed adenocarcinoma, and his serum CEA level returned to normal after the operation. These findings strongly suggested metastatic thymic adenocarcinoma from a colorectal cancer.

• 고려인삼학회:학술대회논문집
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• 고려인삼학회 1993년도 학술대회지
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• pp.61-65
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• 1993

To find out the mechanisms of anticancer effect of ginseng, we performed prospective randomized study for the 39 patients with stomach cancer who had undergone radical subtotal or total gastrectomy and postoperative immunochemotherapy with PMF from July 1991 to November 1991 at Department of Surgery, Seoul National University Hospital. The patients were randomly divided into study and control group: the study group was administered with powdered red ginseng of 5400mg daily dose for 12 months postoperatively, the control group was simply followed-up. There were no significant differences between study and control group in twelve months postoperative body weights, triceps skin fold, hemoglobin. albumin, total protein, PNI, total WEC and lymphocyte count, and T-cell percentage (p>0.05). The results of preoperative DNCB skin test of study group was (0) for 8 patients and (+) for 12 patiens. but after operation, it showed the tendency of decreasing (0) and (+) ratio and increasing tendency of (++) ratio (p<0.05), but those of control group showed no increasing tendency of the degree of positive DNCB skin test. From the above results, we could conclude that ginseng had anti - cancer effect by the way of immune mechanism and could be an adjunct to the patients with stomach cancer postoperatively.

• Asian-Australasian Journal of Animal Sciences
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• 제13권8호
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• pp.1059-1062
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• 2000

The objective of the investigation was to study the effect of intramuscular $PGF_2\;{\alpha}$ and GnRH on estrus behavior and ovarian response in Murrah buffalo heifers. Twelve Murrah buffalo heifers at 32 months of age that had not exhibited behavioral estrus symptom were included in the experiment. Out of 12,4 heifers were in follicular phase (plasma estradiol $57.05{\pm}12.52pg/ml$), another 4 heifers were in luteal phase (Plasma progesterone $2.24{\pm}0.25ng/ml$) while the ovaries of remaining four heifers were inactive (estradiol $23.70{\pm}1.66pg/ml$and progesterone $0.32{\pm}0.06ng/ml$). $PGF_2\;{\alpha}$ (25 mg, Lutalyse, im) and GnRH (200 ug, Fertagyl, iv) was administered to each heifer at interval of 10 days. The plasma progesterone concentration decreased within 48 hrs after $PGF_2\;{\alpha}$ injection and followed thereafter with follicular growth, estrus and ovulation. GnRH administration induced follicular growth, elevation of plasma estradiol concentration with subsequent exhibition of behavioral estrus in 2 out of 4 heifers having inactive ovary. The observation reveals that Murrah buffalo heifers at 32 months of age have developed receptors for $PGF_2\;{\alpha}$ and GnRH on ovarian and pituitary tissue respectively and response the single injection of $PGF_2\;{\alpha}$ and GnRH similar to the mature cycling animals.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제37권
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• pp.8.1-8.6
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• 2015

Background: This study aimed to evaluate the clinical usefulness of autogenous fresh demineralized tooth (auto-FDT) graft prepared at the chairside for alveolar bone grafting during dental implant surgery. Methods: In total, 38 patients requiring both tooth extraction (for endodontic or periodontal reasons or third molar extraction) and alveolar bone regeneration for dental implant placement were included. Within 2 h after clean extraction, the teeth were prepared at the chairside to serve as bone graft material. In the same sitting, blocks or chips of this graft material were used to reconstruct defects at the osteotomy site simultaneously with or before implant placement. Twelve months after prosthesis fabrication and placement, the clinical findings and implant success rates were evaluated. Histological studies were randomly conducted for selected cases. Results: Clinical evaluation showed favorable wound healing with minimal complications and good bone support for the implants. No implant was lost after 12 months of function following prosthetic rehabilitation. Histological examination revealed new bone formation induced by the graft material. Conclusions: Chairside preparation of autogenous fresh demineralized teeth after extraction can be a useful alternative to the use of autogenous bone or other graft materials for the immediate reconstruction of alveolar bone defects to facilitate subsequent implant placement.

• 대한족부족관절학회지
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• 제7권1호
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• pp.61-67
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• 2003

Purpose: We evaluate the clinical, radiologic and pathologic features of giant cell tumor of tendon sheath (GCTTS) in the foot Materials and Methods: Twelve cases of GCTTS excised from foot region, at our hospital from 1999 to 2002, were analyzed. The mean duration of follow up was 19 months. The age and sex of the patient, location and size of the lesion, symptom as well as radiologic findings were evaluated. Results: The most common symptom was painless mass in 7 patients. Three patients had pain sympton and 2 patients had tenderness. The mean duration from identification of the mass to excision was 14 months. Seven cases were located in the forefoot, most commonly in the big toe with 4 cases, 2 cases in the midfoot and 3 cases in the hindfoot. The average diameter along the long axis was 2.8cm. Conclusion: GCTTS in the foot was more common in the big toe and also plantar side same as in the hand. But bony erosion and pain were more frequent than in the hand.

• Journal of Chest Surgery
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• 제26권7호
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• pp.521-525
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• 1993

Sixty-three patients who underwent open mitral commissurotomy at Sejong General Hospital during last 10 years from the August, 1983 to June, 1993 were reviewed There were fifty-one women and twelve men, and the mean age was 34.2 years. According to the NYHA classification, the distribution of patient preoperatively was as follows: class I, 5 patients ; class II, 26 patients ; class III, 30 patients ; class IV, 2 patients, and mean duration of symptome was 4.5 years. The mean mitral valvular area measured with echocardiogram preoperatively was 0.92cm2. All patients underwent open mitral commissurotomy and 41 patients required additional procedures for relief of subvalvular stenosis or other valvular disease. There were no operative death. 63 patients had three different types of mitral stenosis : type I, mobile cusps without subvalvular change [21 patients] ; typeII, thickened cusps with subvalvular change [34 patients] ; type III, rigid cusps with severe subvalvular change [8 patients]. The valvular calcification was seen in 11 patients [17%] and 15 patients [24%] had left atrial thrombus. The duration of follow-up was from 1 month to 168 months [mean, 39.6 months] and there were no late death. Six patients required reoperation and one patient had embolic episode. Conclusively,the open mitral commissurotomy represents a safe surgical precedure for treating mitral stenosis, allowing a complete removal of atrial thrombosis if present, and even when associated with subvalvular changes.