DOI QR코드

DOI QR Code

Metastatic Thymic Adenocarcinoma from Colorectal Cancer

  • Lee, Mina (Department of Thoracic and Cardiovascular Surgery, Inha University Hospital) ;
  • Choi, Suk Jin (Department of Pathology, Inha University Hospital) ;
  • Yoon, Yong Han (Department of Thoracic and Cardiovascular Surgery, Inha University Hospital) ;
  • Kim, Joung-Taek (Department of Thoracic and Cardiovascular Surgery, Inha University Hospital) ;
  • Baek, Wan Ki (Department of Thoracic and Cardiovascular Surgery, Inha University Hospital) ;
  • Kim, Young Sam (Department of Thoracic and Cardiovascular Surgery, Inha University Hospital)
  • Received : 2015.10.08
  • Accepted : 2015.10.19
  • Published : 2015.12.05

Abstract

This report describes the case of a 57-year-old man with an anterior mediastinal tumor. Four years previously, he underwent laparoscopic anterior resection for sigmoid colon cancer. Thirty months after that procedure, bilateral pulmonary metastasectomy was performed. Twelve months later, follow-up computed tomography revealed a 1-cm pulmonary nodule on the upper lobe of the right lung and a solid mass on the anterior mediastinum, and the patient was also observed to have an elevated serum carcinoembryonic antigen (CEA) level. Repeated pulmonary nodule resection and total thymectomy were performed. Immunohistochemical staining of the anterior mediastinal tumor revealed adenocarcinoma, and his serum CEA level returned to normal after the operation. These findings strongly suggested metastatic thymic adenocarcinoma from a colorectal cancer.

Keywords

References

  1. Pastorino U, Grunenwald D. Surgical resection of pulmonary metastases. In: Patterson G, Cooper J, Deslauriers J, Lerut A, Luketrich J, Rice T. Pearson's thoracic and esophageal surgery. 3rd ed. Philadelphia (PA): Churchill Livingstone; 2008. p. 851-63.
  2. Engels EA. Epidemiology of thymoma and associated malignancies. J Thorac Oncol 2010;5(10 Suppl 4):S260-5. https://doi.org/10.1097/JTO.0b013e3181f1f62d
  3. Welsh JS, Thurman SA, Howard SP. Thymoma and multiple malignancies: a case of five synchronous neoplasms and literature review. Clin Med Res 2003;1:227-32. https://doi.org/10.3121/cmr.1.3.227
  4. Tanakaya K, Konaga E, Takeuchi H, et al. Colon carcinoma after thymectomy for myasthenia gravis: report of a case. Surg Today 2002;32:896-8. https://doi.org/10.1007/s005950200175
  5. Yeo SJ, Kim KJ, Kim BY, et al. Metastasis of colon cancer to medullary thyroid carcinoma: a case report. J Korean Med Sci 2014;29:1432-5. https://doi.org/10.3346/jkms.2014.29.10.1432
  6. Jung HY, Cho H, Chung JH, et al. A rare case of primary tubular adenocarcinoma of the thymus, enteric immunophenotype: a case study and review of the literature. J Pathol Transl Med 2015;49:331-4. https://doi.org/10.4132/jptm.2015.04.16
  7. Moser B, Schiefer AI, Janik S, et al. Adenocarcinoma of the thymus, enteric type: report of 2 cases, and proposal for a novel subtype of thymic carcinoma. Am J Surg Pathol 2015; 39:541-8. https://doi.org/10.1097/PAS.0000000000000359
  8. Marx A, Chan JK, Coindre JM, et al. The 2015 World Health Organization classification of tumors of the thymus: continuity and changes. J Thorac Oncol 2015;10:1383-95. https://doi.org/10.1097/JTO.0000000000000654

Cited by

  1. Colorectal Cancer Metastasis to the Thymus Gland: Rare Presentation of Colorectal Cancer as Anterior Mediastinal Mass vol.2017, pp.None, 2015, https://doi.org/10.1155/2017/6581965