• Title/Summary/Keyword: true values

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Added Value of Contrast Leakage Information over the CBV Value of DSC Perfusion MRI to Differentiate between Pseudoprogression and True Progression after Concurrent Chemoradiotherapy in Glioblastoma Patients

  • Pak, Elena;Choi, Seung Hong;Park, Chul-Kee;Kim, Tae Min;Park, Sung-Hye;Won, Jae-Kyung;Lee, Joo Ho;Lee, Soon-Tae;Hwang, Inpyeong;Yoo, Roh-Eul;Kang, Koung Mi;Yun, Tae Jin
    • Investigative Magnetic Resonance Imaging
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    • v.26 no.1
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    • pp.10-19
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    • 2022
  • Purpose: To evaluate whether the added value of contrast leakage information from dynamic susceptibility contrast magnetic resonance imaging (DSC MRI) is a better prognostic imaging biomarker than the cerebral blood volume (CBV) value in distinguishing true progression from pseudoprogression in glioblastoma patients. Materials and Methods: Forty-nine glioblastoma patients who had undergone MRI after concurrent chemoradiotherapy with temozolomide were enrolled in this retrospective study. Twenty features were extracted from the normalized relative CBV (nCBV) and extraction fraction (EF) map of the contrast-enhancing region in each patient. After univariable analysis, we used multivariable stepwise logistic regression analysis to identify significant predictors for differentiating between pseudoprogression and true progression. Receiver operating characteristic (ROC) analysis was employed to determine the best cutoff values for the nCBV and EF features. Finally, leave-one-out cross-validation was used to validate the best predictor in differentiating between true progression and pseudoprogression. Results: Multivariable stepwise logistic regression analysis showed that MGMT (O6-methylguanine-DNA methyltransferase) and EF max were independent differentiating variables (P = 0.004 and P = 0.02, respectively). ROC analysis yielded the best cutoff value of 95.75 for the EF max value for differentiating the two groups (sensitivity, 61%; specificity, 84.6%; AUC, 0.681 ± 0.08; 95% CI, 0.524-0.837; P = 0.03). In the leave-one-out cross-validation of the EF max value, the cross-validated values for predicting true progression and pseudoprogression accuracies were 69.4% and 71.4%, respectively. Conclusion: We demonstrated that contrast leakage information parameter from DSC MRI showed significance in differentiating true progression from pseudoprogression in glioblastoma patients.

Effect of age, season and sex on the blood properties in the Cheju horse (제주마(濟州馬)의 혈액성분(血液成分)에 미치는 연령(年齡), 계절(季節) 및 성(性)의 영향(影響))

  • Han, Bang-kuen;Chang, Duk-gi;Hyun, Hae-sung
    • Korean Journal of Veterinary Research
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    • v.30 no.4
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    • pp.525-532
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    • 1990
  • The values of blood composition were analyzed by age, season, and sex from Chejuhorse in Korea. The results obtained were summarized as follow; 1. The values of white blood cell(WBC), packed cell volume(PCV), mean corpuscular volume (MCV), and mean corpuscular hemoglobin concentration(MCHC) were significantly different between age. The WBC value was decreased with the progress of age and the PCV value was lower in the early age of 1,2 to 3 years than in the higher age of 4 to 5, and over 6 years. 2. The mean value of MCV was increased with the progress of age but the adverse was true in MCHC. 3. In the case of seasons, the values of red blood cell(RBC), WBC, hemoglobin(Hb) PCV, MCV, mean corpuscular hemoglobin(MCH), MCHC, globulin(Glo), albumin/globulin(A/G) ratio, inorganic phosphorus(Pi), cholesterol(Chol), and chlorine(Cl) showed significant differences. The number of RBC was not varied from winter to summer but decreased in autumn. The number of WBC was high in summer and autumn, but low in winter and spring. 4. The values of MCV were high in autumn and winter, but low in spring and summer. 5. The values of MCH and MCHC were similar in spring and summer, but strikingly increased in autumn. 6. The values of Glo and A/G ratio were negatively correlated with the season; The value of A/G ratio was lowest in summer but no differences were observed in spring, autumn and winter. On the other hand, the value of Glo was highest in summer but no differences were observed in spring, autumn, and winter. 7. The values of Pi, Chol, and CI were high in summer and winter, but low in spring and autumn. 8. The values of RBC, MCV, and MCH were significantly different between sex. The value of the RBC count in male was higer than the female, but the adverse is true in MCV, and MCH.

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Determination of Amino Acid Availability and Metabolizable Energy in Protein Feedstuffs by True Amino Acid Availability(TAAA) Method (진정아미노산이용율(TAAA)방법에 의한 단백질공급원의 아미노산 이용율 및 대사에너지 측정)

  • 남궁환;백인기;이희석
    • Korean Journal of Poultry Science
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    • v.20 no.4
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    • pp.189-196
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    • 1993
  • True amino acid availability (TAAA) and true metabolizable energy(TME) values of 8 protein feedstuffs were determined by feeding three roosters exactly 30g of each protein feedstuff after 36h of fasting. From each rooster excreta were collected for 36 h. TAAA were significantly(P<0.01) different among protein feedstuffs. TAAA was highest in fish meal(96.1%), followed by corn gluten(91.2%), rapeseed meal(88.8%), soybean meal(88.7%), meat meal(87.2%), canola meal(86.1%), cottonseeed meal(82.6%) and feather meal(82.5%). Available Iysine values obtained by TAAA method were highly correlated(P<0.01) with those obtained by chick bioassay(CBA) and FDNB method. TME was highest in corn gluten(4,011kcal/kg, as fed basis), followed by fish meal(3,906), feather meal(3,098), soybean meal(3,007), meat and bone meal(2,631), canola meal(2,326), cottonseed meal(2,246) and rapeseed meal(2,120).

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A Study on EOQ Model Involving Estimate Errors (수요, 주문 및 재고비용이 불확실한 상황에서의 EOQ모형에 관한 연구)

  • Kim, Gyu-Tae;Hwang, Hark-Chin;Kim, Chang-Hyun
    • IE interfaces
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    • v.17 no.1
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    • pp.78-83
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    • 2004
  • We consider the sensitivity of average inventory cost rate when true values of the parameters in the EOQ model are unknown over known ranges. In particular, in the case that the valid range on the true economic lot size are known, we provide a formula for estimating the lot size under minimax criterion. Moreover, to estimate the valid range, we apply the propagation of errors technique. Then, we present a scheme to find a (valid) lot size, based on the estimated range of the true lot size from the propagation of errors technique.

Analysis of EOQ Model Involving Estimate Errors (수요, 주문 및 재고비용이 불확실한 상황에서의 EOQ 모형분석)

  • Kim Gyutae;Hwang Hark-Chin;Kim Jong Rae
    • Proceedings of the Korean Operations and Management Science Society Conference
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    • 2003.05a
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    • pp.1028-1034
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    • 2003
  • We consider the sensitivity of average inventory cost rate when true values of the parameters In the EOQ model are unknown over known ranges. In particular, In the case that the valid range on the true economic lot size are known. we provide a formula for estimating the lot size under minimax criterion. Moreover, to estimate the valid range, we apply the propagation of errors technique. Then, we present a scheme to find a (valid) lot size. based on the estimated range of the true lot size from the propagation or errors technique.

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Digestibility of Amino Acids of Maize, Low Tannin Sorghum, Pearl Millet and Finger Millet in Caecectomized Roosters

  • Vasan, P.;Mandal, A.B.;Dutta, Narayan;Maiti, S.K.;Sharma, K.
    • Asian-Australasian Journal of Animal Sciences
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    • v.21 no.5
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    • pp.701-706
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    • 2008
  • The aim of the present study was to determine the apparent and true digestibilities of amino acids of maize, low tannin sorghum, pearl millet and finger millet in adult caecectomized cockerels. Adult cockerels (n = 60), 25-weeks old, were used in this study of which 30 birds were caecectomized as per a standard method. The apparent digestibilities of amino acids of sorghum were not affected by caecectomy, but were higher for maize, finger millet and pearl millet in caecectomized cockerels. Caecectomy had no influence on the true digestibilities of amino acids of maize, but higher digestibilities were observed for most of the amino acids of sorghum and finger millet in caecectomized cockerels. Caecectomy lowered the true digestibility of cystine, threonine and serine of pearl millet. The apparent digestibilities of amino acids of maize, finger millet and pearl millet were underestimated in intact cockerels. The true digestibilities of most of the amino acids of sorghum and finger millet were underestimated, while those of cystine, threonine and serine of pearl millet were overestimated in intact cockerels. The findings suggest that the amino acid digestibility values of cereal grains determined using caecectomized cockerels might be appropriate and reliable for poultry diet formulations. Moreover, the digestibilities of amino acids of finger millet were inferior to other cereal grains, while those of pearl millet were comparable to maize and sorghum.

Efficient hardware implementation and analysis of true random-number generator based on beta source

  • Park, Seongmo;Choi, Byoung Gun;Kang, Taewook;Park, Kyunghwan;Kwon, Youngsu;Kim, Jongbum
    • ETRI Journal
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    • v.42 no.4
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    • pp.518-526
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    • 2020
  • This paper presents an efficient hardware random-number generator based on a beta source. The proposed generator counts the values of "0" and "1" and provides a method to distinguish between pseudo-random and true random numbers by comparing them using simple cumulative operations. The random-number generator produces labeled data indicating whether the count value is a pseudo- or true random number according to its bit value based on the generated labeling data. The proposed method is verified using a system based on Verilog RTL coding and LabVIEW for hardware implementation. The generated random numbers were tested according to the NIST SP 800-22 and SP 800-90B standards, and they satisfied the test items specified in the standard. Furthermore, the hardware is efficient and can be used for security, artificial intelligence, and Internet of Things applications in real time.

Handwritten Numerals Recognition Using an Ant-Miner Algorithm

  • Phokharatkul, Pisit;Phaiboon, Supachai
    • 제어로봇시스템학회:학술대회논문집
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    • 2005.06a
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    • pp.1031-1033
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    • 2005
  • This paper presents a system of handwritten numerals recognition, which is based on Ant-miner algorithm (data mining based on Ant colony optimization). At the beginning, three distinct fractures (also called attributes) of each numeral are extracted. The attributes are Loop zones, End points, and Feature codes. After these data are extracted, the attributes are in the form of attribute = value (eg. End point10 = true). The extraction is started by dividing the numeral into 12 zones. The numbers 1-12 are referenced for each zone. The possible values of Loop zone attribute in each zone are "true" and "false". The meaning of "true" is that the zone contains the loop of the numeral. The Endpoint attribute being "true" means that this zone contains the end point of the numeral. There are 24 attributes now. The Feature code attribute tells us how many lines of a numeral are passed by the referenced line. There are 7 referenced lines used in this experiment. The total attributes are 31. All attributes are used for construction of the classification rules by the Ant-miner algorithm in order to classify 10 numerals. The Ant-miner algorithm is adapted with a little change in this experiment for a better recognition rate. The results showed the system can recognize all of the training set (a thousand items of data from 50 people). When the unseen data is tested from 10 people, the recognition rate is 98 %.

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The Computation of True Thrust Using only the Measured Thrust (측정된 추력 데이터만을 이용한 실제 추력의 계산)

  • Kim Jun-Yeop
    • Journal of the Korean Society of Propulsion Engineers
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    • v.8 no.4
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    • pp.9-15
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    • 2004
  • The measured thrust could be distorted because of the transient response of thrust stand during combustion of rocket motor. As a result of the distorted thrust, it is not easy for us to know the values of thrust peak and thrust duration time. Therefore, it is of great importance to compute the true thrust from the measured thrust. In this study the method to eliminate the transient response from the measured thrust using only the measured thrust was Proposed, and also experimental data were used to approve the proposed method. The result showed that the proposed method would be available to compute the true thrust.

Experimental Study on the Elastic Constants of A Transversely Isotropic Rock by Multi-Specimen Compression Tests Report 2 - Statistical Evaluation and Determination of True Values of Elastic Constants (다중시험편 시험에 의한 평면이방성 암석의 탄성상수 분석연구 제 2 보 - 자료의 통계적 평가와 참값의 결정)

  • Park, Chulwhan;Park, Chan;Jung, Yong-Bok
    • Tunnel and Underground Space
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    • v.22 no.5
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    • pp.346-353
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    • 2012
  • Multi-specimen uniaxial compression test has been carried out in order to find the method to determine the five independent elastic constants from a single standard specimen of a transversely isotropic rock. Total 35 specimens of 7 different angles from a large block of rhyolite presenting the flow structure obviously are used in tests. This second report is to focus on the statistical evaluation of measured strains and analyzed elastic constants. And the determination of their true or near-true values is discussed. As the result of RSD analysis, it turns out that the reliability of measured strains is sufficiently obtained and Saint-Venant approximation is well applicable except 15 degree angled specimen in tests. RSD is decreasing on the increase of the angle of anisotropy. This tendency may be caused not only by the decreasing of the deviation of measured strains, but also by the better applicability of Saint-Venant approximation on the increase of angle. It can be concluded that the analyzed values are considered the near-true ones of five independent constants on the high reliability. But the variation of the apparent Young's modulus expected by these values is not proved to match the measured tendency. It is inferred that the factor to decrease the apparent Young's modulus and/or to increase the shear strain, is present in the test or in the nature of the anisotropy in consideration of this inconsistency.