• Korean Journal Plant Pathology
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• v.12 no.3
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• pp.316-323
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• 1996

비가림재배 포도원에서 발생하는 흰가루병에 대하여 triazole계 살균제 flusilazole, myclobutanil, difenoconazole, penconazole, triflumizole, triadimefon의 방제 효과를 검정한 결과는 다음과 같다. 살균제 처리구의 이병과방율과 이병엽율은 무처리구에 비해 현저히 감소하였고, 이들의 방제가는 과방에서 약제에 따라 94.7∼97.9%, 잎에서 85.5%∼90.9%였으며 대조약제인 polyoxin B의 방제가와 유사한 정도를 보였다. 공시살균제의 보호효과는 살균제를 병발생 1주일전에 살포하는 경우, 살포 3주 후에 방제가는 약제에 따라 72.2∼90.5%였으나 4주 후에는 21.2∼41.6%로 감소하여 대조약제 polyoxin B의 52.5%보다 감소시켰으나 myclobutanil의 발아억제 효과는 약제 농도증가에 크게 영향받지 않았다. 살균제에 침지한 cheesecloth를 포도원 선반에 매달아 조사한 공시살균제의 훈증효과는 살포농도의 2배로 처리했을 때 처리점으로부터 반경 30cm이내의 포도송이에서는 약제에 따라 57.2∼71.1%의 방제가를 보였으나 전체 식물체에서는 49.1∼65.8%로서 10일 간격으로 3회 살포한 것 보다 낮은 방제가를 보였다.

• Bulletin of the Korean Chemical Society
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• v.34 no.11
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• pp.3467-3470
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• 2013

• Archives of Pharmacal Research
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• v.28 no.11
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• pp.1213-1218
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• 2005

N,N-Dialkylditihiocarbamate derivatives have been well known as broad-range fungicides. In this study, the triazole derivatives of ten new N,N-disubstituted dithiocarbamates (3a-j) were synthesized and their structures were identified by spectral and elemental analysis. Results of the antifungal activity studies showed that some of the compounds tested were active against M. canis, M. gypseum, and T rubrum at the concentration of 12.5 $\mu$g/mL when c1otrimazol was used as a standard.

• Journal of the Korean Chemical Society
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• v.54 no.5
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• pp.582-588
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• 2010

The synthesis of benzofuran based 1,3,4-thiadiazoles, 1,3,4-triazoles and 1,3,4-oxadiazole via cyclocondensation of thiosemicarbazides have been carried out by conventional and non-conventional methods in excellent yields of product.

• Archives of Pharmacal Research
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• v.20 no.6
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• pp.647-651
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• 1997

The 6, 6-dibromopenam 6 was treated with $CH_{3}/MgBr$ and carbaldehyde 5 to afford the 6-bromo-6-(1-hydroxy-1-methyl)penicillanate 7, which was reacted with acetic anhybride to give acetoxy compound 8. The deacetobromination of 8 with zinc and acetic acid gave 6-exomethylenpenams, Z-isomer 9 and E-isomer 10, which were oxidized to sulfones 11 and 12 by m-CPBA. The p-methoxybenzyl compounds were deprotected by $AlCl_{3}$ and neutralized to give the sodium salts 13, 14, and 15.

• Bulletin of the Korean Chemical Society
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• v.26 no.4
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• pp.658-660
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• 2005

• Bulletin of the Korean Chemical Society
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• v.16 no.1
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• pp.73-76
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• 1995

• Bulletin of the Korean Chemical Society
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• v.32 no.5
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• pp.1692-1696
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• 2011

The reactions of 1H-1,2,4-triazole (Htr) with $MX_2$ ($ZnCl_2$ for 1; $CdBr_2$ for 2) resulted in two coordination polymers, [Zn(tr)Cl]$_n$ (1) and $[Cd(Htr)_2Br_2]_n$ (2). The structural analyses indicate that 1 and 2 feature a 2D layer and 1D triple chain, respectively. In 1, neighouring Zn atoms are connected by ${\mu}_3-1$ ${\kappa}N$: 2 ${\kappa}N$: $4{\kappa}N-tr^-$ anionic ligand into 6- and 16-membered rings, further grow into a 2D sheet. Cd atoms in 2 are bonded by two ${\mu}_2-Br^-$ bridges and neutral ${\mu}_2$-1 ${\kappa}N$: 2 ${\kappa}N$-Htr to form a 1D triple chain. The fluorescent characterizations of 1, 2 and the free Htr ligand feature simlilar emission peakes at 444, 446 and 423 nm respectively, which can be assigned to intra-ligand ${\pi}-{\pi}^*$ transition of (H)tr. The energy gaps of 5.90 eV for 1, 5.16 eV for 2, and 5.93 eV for Htr suggest that the compounds behave as insulators.

• Bulletin of the Korean Chemical Society
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• v.31 no.7
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• pp.1988-1992
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• 2010

4-Amino-1,2,4-triazole copper complex (4-ATzCu) was synthesized, and its thermal behaviors, nonisothermal decomposition reaction kinetics were studied by DSC and TG-DTG techniques. The thermal decomposition reaction kinetic equation was obtained as: $d\alpha$ / dt =$10^{22.01}$ (1-$\alpha$)[-ln(1-$\alpha$)]$^{1/3}$ exp($-2.75\times10^4$ /T). The standard mole specific heat capacity of the complex was determined and the standard molar heat capacity is 305.66 $J{\cdot}mol^{-1}{\cdot}K^{-1}$ at 298.15 K. The entropy of activation $({\Delta}S^{\neq})$, enthalpy of activation $({\Delta}H^{\neq})$, and Gibbs free energy of activation $({\Delta}G^{\neq})$ are calculated as 171.88 $J{\cdot}mol^{-1}{\cdot}K^{-1}$ 225.81 $kJ{\cdot}mol^{-1}$ and 141.18 $kJ{\cdot}mol^{-1}$, and the adiabatic time-to-explosion of the complex was obtained as 389.20 s.

• Journal of Applied Biological Chemistry
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• v.62 no.4
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• pp.407-415
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• 2019

The biological half-life of pesticides applied on crops is the key indicator for ensuring the safety of agricultural products. The biological half-life is affected by the several factors like growing conditions of the crop, climate, application method, and physicochemical properties of pesticides. In this study, the biological half-life was calculated and the degradation rates of six triazole fungicides sprayed on perilla leaves were evaluated. Moreover, the statistical analysis confirmed the correlation between the biological half-life and physicochemical properties of six triazole pesticides. The recoveries of the six pesticides were between 84.8-104.9%, which satisfied the residual pesticide analysis criteria. The biological half-life of six pesticides sprayed on perilla leaves, calculated using the first-order kinetics model, ranged between 6.4-15.1 days. When the biological half-life and the physicochemical properties were correlated using the principal component analysis: pKa and Log P, the biological half-life was found to be affected by PC1. The correlation coefficient between biological half-life and physicochemical properties (pKa), calculated by Spearman rank-order correlation, was R² = -0.928 (p <0.01). Biological half-life has been shown to correlate with pKa. In conclusion, it can be used as a database for the relationship between biological half-life and physicochemical properties and will contribute to ensure safe supply of agricultural products.