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Synthesis of New Triazolyl-N,N-Dialkyldithiocarbamates as Antifungal Agents  

Ozkirimli Sumru (Istanbul University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry)
Apak T. Idil (Istanbul University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry)
Kiraz Muammer (Istanbul University, Istanbul Faculty of Medicine, Microbiology and Clinical Microbiology Department)
Yegenoglu Yildiz (Istanbul University, Istanbul Faculty of Medicine, Microbiology and Clinical Microbiology Department)
Publication Information
Archives of Pharmacal Research / v.28, no.11, 2005 , pp. 1213-1218 More about this Journal
Abstract
N,N-Dialkylditihiocarbamate derivatives have been well known as broad-range fungicides. In this study, the triazole derivatives of ten new N,N-disubstituted dithiocarbamates (3a-j) were synthesized and their structures were identified by spectral and elemental analysis. Results of the antifungal activity studies showed that some of the compounds tested were active against M. canis, M. gypseum, and T rubrum at the concentration of 12.5 $\mu$g/mL when c1otrimazol was used as a standard.
Keywords
Triazole derivatives; Dithiocarbamates; Antifungal agents;
Citations & Related Records
Times Cited By KSCI : 2  (Citation Analysis)
Times Cited By Web Of Science : 12  (Related Records In Web of Science)
Times Cited By SCOPUS : 12
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