• Biomedical Science Letters
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• v.11 no.2
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• pp.201-209
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• 2005

This study aimed to investigate the cerebroprotective effect of nociceptin on transient focal cerebral ischemia in Sprague-Dawley rats by determining the changes in regional cerebral blood flow (rCBF) and the infarct size. Right middle cerebral artery (MCA) was occluded for 2 hours, and thereafter was followed by reperfusion by an intraluminal monofilament technique. An open cranial window was made on the right parietal bone for determination of continuous changes in rCBF by laser-Doppler flowmetry. The infarct size was morphometrically determined using the 2,3,5-triphenyltetrazolium chloride technique. In normal rats, nociceptin ($0.01\~100\;nmol/kg$, Lv.) increased rCBF and decreased cerebral arterial resistance in a dose-dependent manner. Systemic arterial blood pressure was little affected by nociceptin at the doses of 0.01 and 0.1nmol/kg, but dose-dependently reduced at the doses of 1 nmol/kg or more. In transient cerebral ischemic rats, nociceptin ($0.01\~0.1$ nmol/kg, i.p.) significantly attenuated the postischemic cerebral hyperemia, and progressively increased rCBF. The improving effect of nociceptin on the postischemic rCBF response was markedly blocked by pretreatment with $[Nphe^1]nociceptin(1-13)NH_2$ (1 nmol/kg, i.p.), a selective nociceptin receptor antagonist, but not by naloxone ($3{\mu}mol/kg$, i.p.), a selective opioid receptor antagonist. The cerebral infarct size was significantly reduced by nociceptin ($0.01\~0.1$ nmol/kg) administered i.p. 5 min after MCA occlusion in transient cerebral ischemia of 2-hour MCA occlusion and 22-hour reperfusiion. It is suggested that nociceptin improves the postischemic cerebral hemodynamics and thereby has a cerebroprotective effect in transient focal cerebral ischemia.

• 제어로봇시스템학회:학술대회논문집
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• 2004.08a
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• pp.736-740
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• 2004

In order to overcome the problems of simulation methods, the power system transient stability assessment method using critical fault clearing time functions has been developed. Using the above method, this paper has developed the new method which can assess accurately and efficiently the effects of control and protection systems on transient stability which is the most important characteristic to assess in power systems. At first, critical fault clearing time functions CCT(W:load) are defined by taking notice of the fact that transient stability is mainly controlled by fault clearing time and load. Next, the method to be enable to assess accurately and efficiently the effects of control and protection systems on transient stability has been newly developed by using the above functions. Finally, it has been applied to the effect assessment in the occurrence of a three-phase fault in a model power system. Results of application have been clarified its effectiveness.

• Nuclear Engineering and Technology
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• v.52 no.2
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• pp.258-270
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• 2020

A new task of using the Jacobian-Free-Newton-Krylov (JFNK) method for the PWR core transient simulations involving neutronics, thermal hydraulics and mechanics is conducted. For the transient scenario of PWR, normally the Picard iteration of the coupled coarse-mesh nodal equations and parallel channel TH equations is performed to get the transient solution. In order to solve the coupled equations faster and more stable, the Newton Krylov (NK) method based on the explicit matrix was studied. However, the NK method is hard to be extended to the cases with more physics phenomenon coupled, thus the JFNK based iteration scheme is developed for the nodal method and parallel-channel TH method. The local gap conductance is sensitive to the gap width and will influence the temperature distribution in the fuel rod significantly. To further consider the local gap conductance during the transient scenario, a 1D mechanics model is coupled into the JFNK scheme to account for the fuel thermal expansion effect. To improve the efficiency, the physics-based precondition and scaling technique are developed for the JFNK iteration. Numerical tests show good convergence behavior of the iterations and demonstrate the influence of the fuel thermal expansion effect during the rod ejection problems.

• The Journal of Korean Medicine
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• v.23 no.2
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• pp.108-118
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• 2002

Objective : Acupuncture and herbal medicine have been used to prevent and treat cerebrovascular accident, such as stroke, and many studies of acupuncture and moxibustion concerning stroke have been undertaken in humans and various animals. However, the protective effect of the electroacupuncture (EA) of Huan-do (GB30) on the transient forebrain ischemia injury has not been published. Methods : The nenroprotective effects of EA (2 ms, 10 Hz, and 1 - 2 mA) of GB30 on the transient forebrain ischemia injury were investigated by immunohistochemistry of c-Fos-like protein in Sprague-Dawley rats. Results : The transient forebrain ischemia injury resulted in increased expression of c-Fos-like protein (cFL) in the dentate gyms (DG) and CAl for 6 hrs after ischemia, and EA increased significantly expression of cFL in the CAl and DG. For 48 hrs after, there was delayed expression of cFL at the CAl and DG, representing the sign of neuronal cell death, but EA decreased the delayed expression of cFL, significantly. Conclusion : These results suggest that the nenroprotective effects of EA on transient forebrain ischemia injury may be related to excitatory regulation of cFL at the early stage and inhibitory regulation in the long term.

• Electrical & Electronic Materials
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• v.10 no.3
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• pp.268-273
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• 1997

In this paper the transient electron transport in GaAs bulk is simulated by using ensemble Monte Carlo method. To analyze the transient electron transport the 10000 electrons in the .GAMMA. valley are simulated simultaneously for 10 picoseconds. The electric field-velocity relation is obtained. The high impurity density reduces the negative differential resistance effect. The result of transient average velocity shows the electron velocity in the transient state is faster than that in the steady state. This transient velocity overshoot is caused by the intervalley scattering mechanism. And we confirmed the fact that the energy relaxation time is longer than the momentum relaxation time.

• JSTS:Journal of Semiconductor Technology and Science
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• v.14 no.5
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• pp.609-614
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• 2014

The fringe field effects on the transient characteristics of nano-electromechanical (NEM) memory cells have been discussed by using an analytical model. The influence of fringe field becomes stronger as the size of a cell decreases. By using the proposed model, the dependency of NEM memory transient characteristics on cell parameters has been evaluated.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.23 no.6
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• pp.436-439
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• 2010

SiC power device possesses attractive features, such as high breakdown voltage, high-speed switching capability, and high temperature operation. In general, device design has a significant effect on the switching characteristics. In this work, we report the effect of the interface states ($Q_f$) on the transient characteristics of SiC DMOSFETs. The key design parameters for SiC DMOSFETs have been optimized by using a physics-based two-dimensional (2-D) mixed device and circuit simulator by Silvaco Inc. When the $SiO_2$/SiC interface charge decreases, power losses and switching time also decrease, primarily due to the lowered channel mobilities. High density interface states can result in increased carrier trapping, or more recombination centers or scattering sites. Therefore, the quality of $SiO_2$/SiC interfaces has a important effect on both the static and transient properties of SiC MOSFET devices.

• Journal of the Institute of Electronics Engineers of Korea SP
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• v.41 no.3
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• pp.155-162
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• 2004

This paper concentrated on lip synchronization (lip sync) test for DTV with respect to audio and video signals using a finite digital bitstream In this paper, we propose a new lip sync test method which does not effect on the current program by use of the transient effect area test signals (TATS) and audio-video time index lip sync test signals (TILS).the experimental result shows that the time difference between audio and video signal can be easily measured by captured oscilloscope waveform at any time.

• Proceedings of the KIEE Conference
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• 2007.11b
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• pp.57-59
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• 2007

When onsite power is supplied from grid due to electrical transient in NPP, the effect of the nuclear plant risk will be increased by the change of grid performance. It is important to analyze the effect for bus voltage of onsite according to grid reliability. Therefore, we analytically accomplish the effect for bus voltage by electrical transient in KSNP.

• Journal of the Optical Society of Korea
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• v.15 no.3
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• pp.237-243
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• 2011

Thermal characteristics, such as diffusivity and temperature induced change in the fiber mode index of rotation sensing fiber coil are critical factors which determine the time varying, thermo-optically induced bias drift of interferometric fiber-optic gyroscopes (IFOGs). In this study, temperature dependence of the transient effect is analyzed in terms of the thermal characteristics of the fiber coil at three different temperatures. By applying an analytic model to the measured bias in the experiments, comprehensive thermal factors of the fiber coil could be extracted effectively. The validity of the model was confirmed by the fact that the extracted values are reasonable results in comparison with well known properties of the materials of the fiber coil. Temperature induced changes in the critical factors were confirmed to be essential in compensating the transient effect over a wide temperature range.