• Journal of Physiology & Pathology in Korean Medicine
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• v.22 no.4
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• pp.746-753
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• 2008

East Asian traditional medicine(Asian medicine) should be understood correctly on the basis of Asian medical network. For the correct understanding we analyzed Asian medical history which could be divided into three categories based on Dong-Eui-Bo-Gam. There are three mechanisms of human diseases, which are the pathogenesis of six external etiological factors(wind, cold, summer-heat, dampness, dryness and fire) due to affection by exopathogen [外感六氣], the pathogenesis of five viscera due to internal injury [內傷五藏], and the pathogenesis of physical constitution due to vital activity [生命體質]. While Chinese medicine has mainly developed the pathogenesis of the former two, Korean traditional medicine has mainly developed the pathogenesis of physical constitution.

• Journal of Physiology & Pathology in Korean Medicine
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• v.28 no.3
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• pp.263-270
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• 2014

The objective of this study was to investigate the diagnosis and treatment of Raynaud disease such as syndrome differentiation and herbal medicine by reviewing Chinese traditional medicine's journals. The journal search was carried out using China National Knowledge Infrastructure(CNKI) and PubMed from January 2008 to August 2013. Searching key words were the various combination of "Raynaud disease", "traditional chinese medicine", "syndrome differentiation", "herbal medicine". The final selection of 38 studies were selected and summarized by researchers. The syndrome differentiation was classified as yang deficiency and cold syncope, qi stagnation and blood stasis. The most frequently prescribed herbal medication was Dangguisinitang.

• Journal of Physiology & Pathology in Korean Medicine
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• v.27 no.6
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• pp.818-822
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• 2013

This report is aimed to investigate the effect of Traditional Korean Therapy (TKT) in treating recurred breast cancer metastasized to lung. A 53-year-old woman who was diagnosed as left breast cancer and underwent surgery, adjuvant chemotherapy and radiotherapy in early 2009 was admitted for the treatment of recurred, metastatic lung cancer in late 2012. She was treated with TKT including acupuncture, moxibustion and pharmacopuncture. The effect was evaluated with positron emission tomogram and computed tomogram (PET-CT). The metastatic tumors in both lungs were disappeared after the treatment for about 2 months. These results suggest that TKT is a therapeutic method to treat metastatic lung cancer originated from breast cancer.

• Speech Sciences
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• v.12 no.2
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• pp.59-72
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• 2005

The purpose of this study was to investigate the effects of rhythm therapy program on MPT(Maximum Phonation Time) and acoustic parameters in patients with Parkinson's disease. The therapy program utilized 5 Korean traditional rhythms: jinngyang, jungmori, jungjungmori, jajinmori, and semachi. The therapy consisted of counseling regarding vocal hygiene and actual therapy procedures. Six subjects with Parkinson's disease participated in the study; 3 subjects in experimental group and the other 3 subjects in control group. The pre- and post- acoustic analyses were performed in both groups. The results of this study were as follows; 1) MPT was significantly increased in the experimental group, 2) mono-pitch was significantly improved in the experimental group, 3) mono-loudness was significantly improved in the experimental group, and finally, HNR was significantly increased in the experimental group compared to the control group.

• Journal of Physiology & Pathology in Korean Medicine
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• v.31 no.6
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• pp.305-312
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• 2017

Theory of visceral and meridian system is the most important part in traditional Korean medicine. In theory of visceral system, the aspect of function has been emphasized more than anatomical substance. In this research, the concept of visceral system would be attempted to be expanded from 'five viscera and six bowels' to whole body, and new analysis system composed of genesis, structure, function and operation. The theories of traditional Korean medicine remain at the organ system or organ level, therefore progressive research using the new analysis system is needed to approach tissue and cell levels.

• Journal of Physiology & Pathology in Korean Medicine
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• v.22 no.3
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• pp.528-534
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• 2008

It has been known that Tri-origin theory could describe pertinently the dynamic phenomena of life. From the viewpoint of the asian image-mathematics, the most representative Tri-origin could be Four Images, Five Phases, and Six Qi(six kinds of weather). In Korean traditional medicine, Tri-origin could be meridian system, Jangbu viscera system, and body essence vital energy mentality blood system. Here we reasoned whether asian image-mathematics could be applicable to Korean traditional medicine system, and as a conclusion ; Meridian system belongs to Six Qi, Jangbu viscera system belongs to Five Phases, and body essence vital energy mentality blood system belongs to Four Images.

• Journal of Physiology & Pathology in Korean Medicine
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• v.20 no.1
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• pp.171-173
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• 2006

Trichomonicidal activity of thirty methanolic herbal extracts used in traditional medicine in Korea was evaluated. Trichomonas vaginalis was used as experimental model, and anti-Trichomonas activity was determined over cultures of the parasite in TYM Diamond medium. Six methanolic extracts such as Acanthopanacis Cortex, Agrimoniae Herba, Pulsatillae Radix, Sanguisorbae Radix, Sophorae Radix, and Torilidis Fructus showed more than 50% trichomonicidal activity at the concentration of 200 g/ml. These extracts were further fractionated into n-butanol soluble and aqueous phases. Except for Acanthopanacis Cortex, all of n-butanol soluble phases showed potent trichomonicidal activity, while none of aqueous phases exhibited trichomonicidal activity.

• The Journal of Internal Korean Medicine
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• v.32 no.1
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• pp.26-32
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• 2011

Objectives : Non-alcoholic fatty liver disease (NAFLD) is known to be increasing and becoming a health-related issue worldwide. This study aimed to analyze its prevalence and characterize NAFLD. Methods : NAFLD-related papers were surveyed via PubMed and in Korean medical journals, and then the prevalence and pathology were reviewed. Results : The prevalence of NAFLD in the general population is around 10~30% worldwide. The prevalence of NAFLD in Korea is estimated as 15~30%, which is higher than in China and Japan. The most important etiological-factors of NAFLD include central obesity resulting from excessive calorie intake and less physical activity, which lead to adiponectin hypoactivity and insulin resistance. The Oriental medicine view point of NAFLD pathology is phlegm-dampness by dysfunction of free flow in liver. Conclusions : This study provided an overview of the prevalence and pathology of NAFLD, and can support the development of a strategy for traditional Korean medicine-based prevention or treatment of NAFLD.

• Journal of Physiology & Pathology in Korean Medicine
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• v.19 no.5
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• pp.1386-1390
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• 2005

Lycii Fructus (LF) has been reported to possess various biological activities. In this study, we investigated the anti-inflammatory and anti-allergic effects of LF extract in lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophage cells and rat peritoneal mast cells(RPMC). LF extract inhibited NO production and the expressions of inducible NO synthase (iNOS) mRNA and enzyme protein, determined by Griess reactions, RT-PCR and Western blotting, respectively, in LPS-stimulated RAW 264.7 macrophages cells. LF extract significantly inhibited histamine release in compound48/80 stimulated rat peritoneal mast cells compared with the compound48/80 only treated cells. It is suggested that the LF extract can improve the inflammation status that involves the histamine release.

• Journal of Physiology & Pathology in Korean Medicine
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• v.21 no.6
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• pp.1450-1455
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• 2007

Evodiae Fructus(EF) has been used as Traditional medicine for the treatment of headache, abdominal pain, hemorrhage, and menorrhae in many Asian countries. The present study was conducted to investigate the immunomodulatory effect on cyclophosphamide(CY)-induced immunesuppression of water extracted EF(EFE). In the mouse spleen cell proliferation assay, EFE enhanced mitogenic activity and restored the CY-induced cell suppression. In the nitric oxide(NO) assay, EFE inhibited NO production and iNOS protein levels in LPS-stimulated RAW 264.7 cells. In the GC-MS analysis, many ingredients of EFE were detected by solvents. These results indicated that EFE can modulate immune response through immune cell proliferation, the regulation of NO production and the inhibition of CY-induced immunotoxicity.