• Title/Summary/Keyword: traditional oriental prescription

Search Result 233, Processing Time 0.022 seconds

A Review of Statistical Analysis Methods Applied on Traditional Korean Medicine Research (한의학 연구에 활용된 통계분석 방법에 대한 고찰)

  • Jang, Seon-Il;Yun, Young-Gab;Choi, Kyoung-Ho
    • Herbal Formula Science
    • /
    • v.17 no.1
    • /
    • pp.75-83
    • /
    • 2009
  • Objective : The purpose of this study is to indicate of problems in statistical analysis method of "The Korean Journal of oriental Medical Prescription" and we will be proposed the useful application of the statistical analysis method. Methods : In this paper, we were analysed statistical analysis methodology from published journal articles "The Korean Journal of Oriental Medical Prescription" December, year 2000 to December, year 2008. We were investigated of problems in application of structured analysis methods those journal articles that including statistical analysis techniques and analysis methods. Results : 1. A random allocation of the experimental group and control groups are important factors in the planning process of statistical analysis. However, there are less explanation those journal articles. 2. There are no consideration in specimen size that there will be considerate by the level of significance and statistical test. 3. Many article authors were confused between parametric methods and non-parametric methods that they were applied parametric statistical analysis methods although inapplicable sample size. 4. There were applied the parametric methods consists of t-test instead non-parametric methods in the comparison of average intergroup relations. 5. There were less understanding posterior analysis and were confused with t-test. Conclusion : Our goal was to outline the key methods with a brief discussion of problems(statistical analysis methods), avenues for solutions. we recommend authors to use an appropriate statistical analysis methods for obtaining a more cautions results.

  • PDF

An experimental study for the development of prescription on atopic dermatitis (아토피 피부염 외치치료제 처방 개발을 위한 실험적 연구)

  • Kim, Gun Woo;Bak, Ji Won;Sim, Boo-Yong;Kim, Dong Hee
    • The Korea Journal of Herbology
    • /
    • v.29 no.4
    • /
    • pp.13-20
    • /
    • 2014
  • Objectives : Atotang was composed of 10 kinds of traditional medicinal herb. This research was performed to examine biological effects of Atotang for the development of prescription on atopic dermatitis. Methods : Atotang was extracted with 80% EtOH. Free radical scavenging assay has tested for anti-oxidative activity as well as the contents of total polyphenol. We observed the production of ROS, nitric oxide(NO) and the inflammatory cytokines such as interleukin-1beta(IL-${\beta}$), IL-6, tumor necrosis factor-alpha(TNF-${\alpha}$), Prostaglandin E2($PGE_2$) in Raw 264.7 cells stimulated by LPS. We used Disc diffusion method to investigate antibacterial activity on Candida albicans, Staphylococcus aureus and Staphylococcus epidermis. Result : Content of total phenolic compound of Atotang was 36.3 mg/g ext. DPPH and ABTS scavenging activities were 77% and 46% at 200 ug/ml respectively, showing dose-dependent increase. The amounts of ROS and NO in RAW 264.7 cells were decreased by 30% and 19% at 200 ug/ml, respectively, showing dose-dependent decrease. The prodcution of IL-1beta, IL-6 and TNF-alpha in RAW 264.7 cells were decreased dose-dependently by 81%, 67%, and 20% at 200 ug/ml, respectively. Atotang was reduced LPS-stimulated production of $PGE_2$ by 33%. Atotang on C. albicans, S. aureus and S. epidermis was selected by a disc diffusion method and inhibition effect of the Atotang on the growth of S. epidermis was the greatest. Conclusion : The results indicated that Atotang showed biological activities showing anti-oxidant, anti-inflammatory and antibacterial effects. Based on these results, it is concluded that Atotang can be applied to the prescription on atopic dermatitis.

Cytotoxic Effect of Korean Traditional Prescriptions on the Human Gastric Cancer Cell Lines (한약처방제의 인체 위암 세포주에 대한 세포독성 효과에 관한 연구)

  • Kim, Eun-Hae;Eun, Young-Ah;Kang, Bong-Joo;Sung, Hyun-Jae;Park, Kap-Joo
    • Korean Journal of Pharmacognosy
    • /
    • v.28 no.4
    • /
    • pp.233-238
    • /
    • 1997
  • ln order to search for antigastric cancer agents from Korean traditional prescriptions. We selected 41 traditional prescriptions, based on a review of the Korean traditional medicine books. Both boiling water and methanol extracts were tested, by means of the Sulforhodamine B (SRB) protein assay. Six of the 41 water extracts; #3, #34, #35, #38, #40, #41 showed efficacy against gastric cancer cell (AGS: Human gastric carcinoma, ATCC HTB 103). #3 inhibited 50% cancer cell growth1 at the concentration of $152\;{\mu}g/ml$, #34, #35, #38, #40 and #41 inhibited 50% cancer cell growth at the concentration of $145\;{\mu}g/ml$, $129\;{\mu}g/ml$, $173\;{\mu}g/ml$, $10\;{\mu}g/ml$ and $19\;{\mu}g/ml$ respectively. Ten of the 41 methanol extracts; #1, #3, #32, #33, #35, #36, #37, #38, #41 were active. #1 inhibited 50% cancer cell growth at the concentration of $206\;{\mu}g/ml$, #3, #32, #33, #35, #36, #37, 738, #40, #41 inhibited 50% cancer cell growth at the concentration of $133\;{\mu}g/ml$, $159\;{\mu}g/ml$, $199\;{\mu}g/ml$, $147\;{\mu}g/ml$, $113\;{\mu}g/ml$, $187\;{\mu}g/ml$, $130\;{\mu}g/ml$, $9\;{\mu}g/ml$, $15\;{\mu}g/ml$ respectively. Prescription #3, #35, #38, #40, #41 were also interesting because both methanol and water extracts were active.

  • PDF

A Study of Method about Gathering-analysis, of Legal Guarantee Device about Offerer Rights in Oriental Herbal Prescription-mystique (한방처방비법등의 수집분석방법 및 자료제공자등의 권리에 대한 법적보장방안연구)

  • 이지연;김홍준;주영승;이기성;박상구;이상정
    • The Journal of Korean Medicine
    • /
    • v.21 no.4
    • /
    • pp.159-173
    • /
    • 2000
  • Objectives : First, to restore reliability of oriental prescriptions that are effective against incurable diseases, Second, in the short term, to secure the validity of traditional remedies with the help of accumulated data and in the long term, develop new therapeutic methods and prescriptions in order to broaden its aspect in the field of medicine. Third, to maintain predominance on oriental therapeutic methods and put it into practical use based upon the results obtained by this paper. Methods : In the primary sub-thesis(herbalogical analytic methods applied on unknown oriental prescriptions), models of analytic method and in gathering information that could be put into practice are being revised In the secondary sub-thesis(method in gathering and analysing in dealing with oriental prescription), several statistical approaches and analysis on data that has been gathered are being revised. In the tertiary sub-thesis(research on legal guarantee of the offerer rights), an alternative scheme that covers the limitations of the legislative content in dealing with offerer rights is being revised Results : This research has revealed several problems, including those which were foreseen, in proceeding with the project. The prospect of the involvement of the medical personnel engaging in the field of oriental medicine was remarkably bright. Given the condition that the project will proceed as it follows, unknown oriental prescriptions and remedies which have been particularly ignored will eventually play an important role in clinical practice. Conclusions : It is clear to everyone that these oriental remedies will remain ignored by the public unless they gain popularity. Strict verifications on these oriental remedies are definitely needed in order to overcome this limitation. Finally, it should provide a momentum in the field of medicine in gaining popularity to the public.

  • PDF

Preventive Effects of Sihosamultang Extract on Lipid Peroxidation by Free Radicals and Oxidative Damage of Hepatocytes by tert-Butyl Hydroperoxide (시호사물탕이 t-BHP로 유도된 간세포의 산화적 손상 및 자유기에 의한 지질과산화 반응에 미치는 영향)

  • Kim Tae-Gi;Park Sun-Dong;Moon Jin-Young
    • Herbal Formula Science
    • /
    • v.8 no.1
    • /
    • pp.241-255
    • /
    • 2000
  • Sihosamultang(SST) has been used for the treatment of puerperal fever, liver disease in traditional medicine. The present study was carried out to evaluate the antioxidant effects of SST extract in vitro. The inhibitory effect of SST extract on lipid peroxidant was examined in the linoleic acid autoxidation system. In this test, SST extract significantly inhibited the time course of the lipid peroxidation. And SST extract showed about 73% scavenging effect on DPPH radical. And this extract inhibited not only the lipid peroxide formation induced by hydroxyl radical derived from $ H_{2}O_{2}-Fe^{2+}$ in the rat liver homogenate, but also the superoxide generation from xanthine-xanthine oxidase system in a dose-dependent manner. In addition, SST extract protected the hepatic cell death induced by tert-butyl hydroperoxide. These data indicated that SST might play a protective role against oxidative injury by free radicals.

  • PDF

Prevention effect of Sunkiwhajung-tang, a prescription, on the gastric ulcer induced by indomethacin in rats (순기화중탕이 Indomethacin으로 유발된 위궤양에 미치는 영향)

  • Kim Sang Chan;Lee Dong En;Kwon Young Kyu
    • Journal of Physiology & Pathology in Korean Medicine
    • /
    • v.17 no.2
    • /
    • pp.326-337
    • /
    • 2003
  • In order to evaluate the prevention effect of Sunkiwhajung-tang (SWT) which has been used as a traditional prescription for the treatment of digestive disease in Korea on the gastric ulcer induced by indomethacin in rats, the changes of number and size of ulcerative lesions, parietal, chief, Grimelius and Serotonin-positive cells in the peri-ulcerative tissues were detected with histological examinations of ulcerative and peri-ulcerative lesions after oral injections of SWT extracts (125, 250 and 500 mg/kg, respectively). SWT prevented to a great extent the expected indomethacin-induced elevation in hemorrhagic ulcerative lesions, the number and size of ulcerative lesions, and the number of parietal cell, chief cell, Grimelius-positive cells and Serotonin-positive cells in the peri-ulcerative lesions in a dose dependent manner. These results provide a story evidence that SWT produced an protective effect on gastric ulcer induced by indomethacin. Determination of the specific mechanisms involved in the protective effect of SWT on the gastric ulcer will require additional study.

A Review on Prescriptions for Mouth and Teeth in 「Throat, Mouth and Teeth」 of 『Yuyaoyuanfang』 (『어약원방(御藥院方)』 「인후구치문(咽喉口齒門)」 중 치아질환 처방에 관한 고찰)

  • Shin, Jae-Hyuck;Song, Ji-Chung;Maeng, Hak-Young;Eom, Dong-Myung
    • The Journal of Korean Medical History
    • /
    • v.25 no.1
    • /
    • pp.81-91
    • /
    • 2012
  • Objectives : "Yayaoyuanfang" is a prescription book, compiled by Xuguozhen in 1267. In "Yayaoyuanfang", there are 13 chapters including "Throat, Mouth and Teeth". Because there are few prescription books focused only on mouth and teeth disease in traditional medicine, "Throat, Mouth and Teeth" in "Yayaoyuanfang" is distinctive. Methods : We try to analyze prescriptions by form, effectiveness and report experiences in "Yayaoyuanfang". Results : There are 95 prescriptions with 77 powder, 5 paste, 5 liquid, 2 granule and 5 other forms. Effectiveness of those are divided into teeth, gum and mouth. Effectiveness for teeth are about pains, weakness, cavity, discoloration and so on. Effectiveness for gum are about pain, swelling, weakness, shrinking, etc. Effectiveness for mouth is about bad breath. Conclusions : "Throat, Mouth and Teeth" in "Yayaoyuanfang" has professional prscriptions for throat, mouth and teeth with several form and effectiveness.

A study of the tendency of anti-cancer experimental study using herbal medicines (한약(韓藥)을 이용(利用)한 항암(抗癌) 실험연구(實驗硏究)의 경향(傾向)에 관(關)한 고찰(考察))

  • Kim, Hyung-A;Lim, Sung-Woo;Lee, Won-Chul
    • THE JOURNAL OF KOREAN ORIENTAL ONCOLOGY
    • /
    • v.4 no.1
    • /
    • pp.211-232
    • /
    • 1998
  • Because there were lots of side effects and tolerances to the existing anticancer therapeutics, the experiment extracting the anticancer effect from medicinal herbs is in progress liviely. Therefore the purpose of this study were to research the tendency and the course of anticancer studies. To research the tendency of anticancer studies, medicinal herbs of fifty three experimental papers were analyzed and to examine the course of studies, anticancer papers in the medical world were used. The obtained results were as follows: Methods of herbal medicinal treatments were elimination the pathogenic factor(祛邪) and supporting healthy energy(扶正) method used. In this study, immediately tumor bearing and immune response were the most important point. The subject of immediately tumor bearing was not in the specific cancer but in the influence on the life span of general cencerous cells. In the experimental study of immune response, the effect on NK cell activity of medicinal herbs most studied. The combined usage of medicinal herbs and anticancer agent mostly intended to know whether it inhibits the tumor cell growth. The serum test and blood cell number test show if medicinal herbs inhibit side effect of anticancer agent. More than 80 percents of used medicinal herbs, there were anticancer activities. However anticancer experimental studies using medicinal herbs two weak points. The one, it was difficult to choose a prescription according to differentiation of symptoms and signs(辨證論) of the Oriental Medicine, because we put to the test not a man but a mouse. The other, as we observed the indirect effect of the whole physiological regulation caused by synergic effects of the complex prescription, we don't understand the detailed mechanism of the herb. Therefore, if the anticancer effect of the herb is proved the experiment, we should research the concrete medical action of medicinal herbs and immunological analysis of herbal medicines to the body.

  • PDF

KAP Study on Chinese Traditinal Doctor, Hospital and Medicine in China (최근 일부 중국인(中國人)의 중의사(中醫師).중의학(中醫學) 관련 인식(認識).태도(態度) 및 의료행위(醫療行爲)에 관한 연구)

  • Lee, Sun-Dong;Kim, Myung-Dong
    • The Journal of Korean Medicine
    • /
    • v.18 no.2
    • /
    • pp.187-198
    • /
    • 1997
  • The degree of KAP study on Chinease traditional medicine and doctor was examined with some chinease living yenbian district(延邊) from July 1st to August 30th in 1996. The result of the study for predicting health and ill patterns runs as fellows. 1. It is understand to strength and variety about role of chinease traditional medicine doctors and the curable disease. 2. Although most patients go to chinease traditional medicine clinic for the purpose of medicine herbs in package, acupuncture and industry-made pharm, they think the medical fee a little high(70.6%). 3. The 66.7% of respondents recognize chinease traditional medicine doctors as a profession and others think them only abundant works ; therefore it is rather low to ink chinease traditional doctors a profession. 4. Most respondents think that chinease traditional medicine should improved in the inside ; such as scientific reinforcement of theory, lack of univerality, improvment and enlargement of insurance, unkindness, shortage of publicity, dropped equipment, system of medical specialist, lack of integration with westem medicine, exact diagnosis and confidence of remedy, and low efficacy, etc. 5. Chinease likes more experienced-traditional doctor than beginner(78.3%) 6. The policy of korean government against 100 herbal prescription right by western pharmacy has taken the negative recognition(74.6%), 7. The degree that acknowleges of chinease traditional medicine through thease basic contents is average 47.3 mark. To be brief, although the step of the recognition and attitude of oriental medicine is less or very affirmative aspect, actully considerable positive factors is in the last chosen step. In conclusion KAP study connected chinease traditional medicine and doctor has very much postive factors.

  • PDF

Traditional Korean medicine theory based-therapeutic potential of Gung-Gwi-Tang on postpartum obesity: psychosocial aspects of postpartum obesity

  • Kim, Jeong-Hwa;Moon, Phil-Dong
    • CELLMED
    • /
    • v.2 no.3
    • /
    • pp.24.1-24.5
    • /
    • 2012
  • Obesity is psychological and socioeconomic problems as well as health problems related to physical disease and disorder. The obesity epidemic, including a marked increase in the prevalence of obesity among pregnant women, represents a critical public health problem throughout the world. Gung-Gui-Tang (GGT), a prescription of traditional Korean medicine, has been used to treat dizziness due to loss of blood as well as static blood after childbirth. However, the therapeutic potential of GGT on postpartum obesity has not been fully elucidated in an experimental model. In our research, GGT inhibited the increases of body weight and adipose tissues in postpartum mice fed a high-fat diet. GGT also inhibited the elevations of plasma lipid profiles such as triglyceride, low-density lipoprotein cholesterol, total cholesterol, and glutamate pyruvate transaminase. Overall, these results provide evidence that GGT can help to inhibit postpartum obesity and open new perspective to recover the shape of mother into the moment of conception.