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http://dx.doi.org/10.5667/tang.2011.0003

Traditional Korean medicine theory based-therapeutic potential of Gung-Gwi-Tang on postpartum obesity: psychosocial aspects of postpartum obesity  

Kim, Jeong-Hwa (Graduate School of Social Welfare, Ewha Womans University)
Moon, Phil-Dong (Department of Pharmacology, College of Oriental Medicine, Institute of Oriental Medicine, Kyung Hee University)
Publication Information
CELLMED / v.2, no.3, 2012 , pp. 24.1-24.5 More about this Journal
Abstract
Obesity is psychological and socioeconomic problems as well as health problems related to physical disease and disorder. The obesity epidemic, including a marked increase in the prevalence of obesity among pregnant women, represents a critical public health problem throughout the world. Gung-Gui-Tang (GGT), a prescription of traditional Korean medicine, has been used to treat dizziness due to loss of blood as well as static blood after childbirth. However, the therapeutic potential of GGT on postpartum obesity has not been fully elucidated in an experimental model. In our research, GGT inhibited the increases of body weight and adipose tissues in postpartum mice fed a high-fat diet. GGT also inhibited the elevations of plasma lipid profiles such as triglyceride, low-density lipoprotein cholesterol, total cholesterol, and glutamate pyruvate transaminase. Overall, these results provide evidence that GGT can help to inhibit postpartum obesity and open new perspective to recover the shape of mother into the moment of conception.
Keywords
Gung-Gui-Tang; postpartum obesity; body weight; high-fat diet; plasma lipid profiles;
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1 Bermudez FF, Forbes JM, Jones R. Feed intakes and meal patterns of sheep during pregnancy and lactation, and after weaning. Appetite. 1989;13:211-222.   DOI
2 Brown WV, Fujioka K, Wilson PW, Woodworth KA. Obesity: why be concerned? Am J Med. 2009;122:S4-11.   DOI   ScienceOn
3 Carter AS, Wood Baker C, Brownell KD. Body mass index, eating attitudes, and symptoms of depression and anxiety in pregnancy and the postpartum period. Psychosom Med. 2000;67:264-270.
4 Choi BH. Effect of Cnidii Rhizoma Water Extract on the Cerebral Blood Flow. (Iksan, Republic of Korea: Master's thesis from Wonkwang University), 2004.
5 Davis EM, Stange KC, Horwitz RI. Childbearing, stress and obesity disparities in women: a public health perspective. Matern Child Health J. 2012;16:109-118.   DOI
6 Friedewald WT, Levy RI, Fredrickson DS. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem. 1972;18:499-502.
7 Gustafsson PE, Persson M, Hammarstrom A. Socio-economic disadvantage and body mass over the life course in women and men: results from the Northern Swedish Cohort. Eur J Public Health. 2012;22:322-327.   DOI
8 Hong WS. HwangJeNaeGyeongYeongChu. (Seoul, Republic of Korea: Oriental Medicine Research Center Press), 1985.
9 Huh J. DongUiBoGam. (Seoul, Republic of Korea: BUBIN PUBLISHERS CO.), 1999
10 Kim DI, Kim SW, Kim JH, Kim CW, Kim HJ, Baek SH, Song BK, Yu DY, Yu SG, Yun MH, Lee KS, Lee DG, Lee DN, Lee IS, Lee TK, Lee HJ, Im EM, Jang JB, Jeong JH, Jo JH, Jo HB, Jin CS. HanBangYeoSeongUiHak (Seoul, Republic of Korea: JEONGDAM BOOKS), 2007.
11 Kim WH, Choi DY. JangBuByeonJeungRonChi (Seoul, Republic of Korea: SEONGBOSA), 1985.
12 Lau C, Rogers JM, Desai M, Ross MG. Fetal programming of adult disease: implications for prenatal care. Obstet Gynecol. 2011;117:978-985.   DOI   ScienceOn
13 Lee CF, Hwang FM, Liou YM, Chien LY. A preliminary study on the pattern of weight change from pregnancy to 6 months postpartum: a latent growth model approach. Int J Obes (Lond). 2011;35:1079-1086.   DOI
14 Pedersen P, Baker JL, Henriksen, TB, Lissner L, Heitmann BL, Sorensen T, Nohr EA. Influence of psychosocial factors on postpartum weight retention. Obesity. 2011;19:639-646.   DOI
15 Mokdad AH, Bowman BA, Ford ES, Vinicor F, Marks JS, Koplan JP. The continuing epidemics of obesity and diabetes in the United States. JAMA. 2001;286:1195-1200.   DOI   ScienceOn
16 Ng SF, Lin RC, Laybutt DR, Barres R, Owens JA, Morris MJ. Chronic high-fat diet in fathers programs ${\beta}$-cell dysfunction in female rat offspring. Nature. 2010;467:963-966.   DOI
17 Ozaki M, Fuchinoue S, Teraoka S, Ota K. The in vivo cytoprotection of ascorbic acid against ischemia/reoxygenation injury of rat liver. Arch Biochem Biophys. 1995;318:439-445.   DOI   ScienceOn
18 Pitt B, Mancini GB, Ellis SG, Rosman HS, Park JS, McGovern ME. Pravastatin limitation of atherosclerosis in the coronary arteries (PLAC I): reduction in atherosclerosis progression and clinical events. PLAC I investigation. J Am Coll Cardiol. 1995;26:1133-1139.   DOI
19 Rasouli N, Kern PA. Adipocytokines and the Metabolic Complications of Obesity. J Clin Endocrinol Metab. 2008;93:S64-73.   DOI
20 Reck C, Hunt A, Fuchs T, Weiss R, Noon A, Moehler E, Downing G, Tronick EZ, Mundt C. Interactive regulation of affect in postpartum depressed mothers and their infants: an overview. Psychopathology. 2004;37:272-280.   DOI
21 Reck C, Hunt A, Fuchs T, Weiss R, Noon A, Moehler E, Downing G, Tronick EZ, Mundt C. Interactive regulation of affect in postpartum depressed mothers and their infants: an overview. Psychopathology. 2004;37:272-280.   DOI
22 Van Lieshout RJ, Taylor VH, Boyle MH. Pre-pregnancy and pregnancy obesity and neurodevelopmental outcomes in offspring: a systematic review. Obes Rev. 2011;12:e548-559.   DOI
23 Singh GK, Siahpush M, Hiatt RA, Timsina LR. Dramatic increases in obesity and overweight prevalence and body mass index among ethnic-immigrant and social class groups in the United States: 1976-2008. J Community Health. 2011;36:94-110.   DOI
24 Stienstra R, Duval C, Muller M, Kersten S. PPARs, Obesity, and Inflammation. PPAR Res. 2007;2007:95974.
25 Sundaram S, Harman JS, Peoples-Sheps MD, Hall AG, Simpson SH. Obesity and Postpartum Depression: Does Prenatal Care Utilization Make a Difference? Matern Child Health J. 2012;16:656-667.   DOI
26 Whichelow MJ. Letter: Calorie requirements for successful breast feeding. Arch Dis Child. 1975;50:669.