• 제목/요약/키워드: traditional Chinese medicine(TCM)

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『의방유취』를 이용한 한의학 치료기술 개발의 가능성에 대한 모델링 연구 (A study of the value of Korean medical text "Uibang Yuchi(醫方類聚)" as a representative Database for developing new diseases treatment skills)

  • 차웅석;장영재;나지원;안상우
    • 한국의사학회지
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    • 제36권1호
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    • pp.143-154
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    • 2023
  • This paper is a study that considers how current scientific medicine could be supported by traditional medicine, and if the scope of this support is expected to gradually widen. This study begins by understanding the process by which Traditional Chinese Medicine (TCM) has developed interventions for COVID-19. We then examine what support is offered by the ancient Korean medical text "Uibang Yuchi". This paper insists that a key database is absolutely necessary to develop treatment techniques for new diseases. The key database should be considered not only from the point of view of knowledge but also from the point of view of intellectual property rights, and for this reason, the text of "Uibang Yuchi" is important. This paper shows the process of how a new treatment technique can be derived from the ancient book "Uibang Yuchi". We expect that the suggested model would play a role as a reference model in the process of pursuing similar strategies in the future.

중의 약재로부터 피부 미백제의 탐색 (The Study on the Whitening Effects of Traditional Chinese Medicines)

  • ;;이수연;김영희;박선기;오선택;김기호
    • 대한화장품학회지
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    • 제35권4호
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    • pp.257-263
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    • 2009
  • 본 연구에서는 미백 화장품 원료를 개발하기 위해 중국에서 전통적으로 사용되어 오던 47종의 천연약재 또는 복합처방 중에서 멜라닌 생성 저해 효과를 지닌 원료를 찾고자 하였다. 그 중 버섯 티로시나제 활성 실험에서는 저해 효과를 보이지 않았으나, B16-F10 멜라닌 생성세포(B16-F10 melanoma cell)를 이용하여 류기노와 단삼을 선별하였으며 단삼에서 단삼소(丹蔘素, $\alpha$,3,4-trihydroxybenzenepropanoic acid sodium salt)를 분리하여 B16-F10 멜라노마 세포를 이용하여 멜라닌 생성 억제에 관한 실험을 실시하였다. 류기노와 단삼소는 농도에 따라 멜라닌 생성을 억제하였으며, 류기노는 $300\;{\mu}g/mL$의 농도에서 약 60%, 단삼소는 $100\;{\mu}g/mL$의 농도에서는 약 50%의 멜라닌 생성 저해 효과를 보였다. 따라서 연구 결과로써 얻어진 2종의 원료는 새로운 천연 미백 소재로 적용할 수 있을 것으로 기대된다.

야제 (夜啼)의 한의학 치료에 대한 최신 중의학 임상 연구 동향 -2000년대 이후 발표된 임상 연구 논문을 중심으로- (Review of Clinical Research Literatures on Effect of Traditional Chinese Medicine for Pediatric Night Crying)

  • 김상민;이진용;이선행;도태윤
    • 대한한방소아과학회지
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    • 제32권3호
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    • pp.100-118
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    • 2018
  • Objectives The purpose of this study is to analyze some of the TCM (traditional Chinese medicine) clinical research literatures about pediatric night crying in order to learn clinical application of Korean medicine treatment for pediatric night crying. Methods We searched clinical trial literatures about TCM treatment of pediatric night crying from the CNKI (China National Knowledge Infrastructure) (January 2000 to June 2018). We analyzed the literature in regards to the treatment methods and the results. Results Among the 459 searched studies, 13 randomized controlled trials and 41 case studies were selected and analyzed. In most of the studies, the effectiveness of TCM in treating patients was significantly high, so we confirmed the effectiveness of TCM on pediatric night crying. The most commonly used pattern differentiations (辨證) were Spirit damage due to fright and fear (驚恐傷神), Spleen deficiency and cold (脾虛寒) and Heart fire heat (心火熱). Methods of treatment include herbal medicines (internal medicine and external application), massage therapy (Tuina methods), acupuncture and other treatments (bloodletting). The most commonly used herb medicines were Cicadidae Periostracum (蟬?), Poria Cocos (茯?), Glycyrrhizae Radix (甘草), Uncariae Ramulus et Uncus (釣鉤藤), Junci Medulla (燈心草), Fossilia Ossis Mastodi (龍骨), Atractylodis Rhizoma Alba (白朮), Cinnabaris (朱砂), and Coptidis Rhizoma (黃連). The most commonly used massage methods were Clearing Liver Channel (淸肝經), Clearing Heart Channel (淸心經), Kneading $Xi{\check{a}}oti{\bar{a}}nx{\bar{i}}n$ (?小天心), Supplementing Spleen Channel (補脾經), Clearing $Ti{\bar{a}}nh{\acute{e}}shu{\check{i}}$ (淸天河水), and Rubbing Abdomen (摩腹). Conclusions Based on the results of clinical studies from China, the use of Korean medicine for the treatment of pediatric night crying has been shown to be effective in relieving symptoms. Based on the results of this study, it is possible to widen the scope of Korean medicine by additionally reviewing clinical and experimental studies on pediatric night crying.

화병(火病) 유사 병증의 한의학적 치료에 대한 임상연구 동향분석 - CNKI를 중심으로 (Analysis of Clinical Research Trends on Traditional Chinese Medicine Treatment for Depression Syndrome Similar to Hwabyung: Focusing on CNKI)

  • 최은지;서효원;김종우;정선용
    • 동의신경정신과학회지
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    • 제28권4호
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    • pp.349-358
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    • 2017
  • Objectives: To analyze whether a concept similar to Korean 'Hwabyung' exists in China. We investigated the status of clinical studies conducted in China for relevant diseases and trends of the traditional Chinese medicinal (TCM) treatment adopted in clinical studies. Methods: To explore the concept of a condition similar to Korean Hwabyung in China, we searched for the existence of concept and pattern that were parallel or similar to those of Hwabyung in TCM text-books and diagnostic guidelines. We searched and analyzed clinical studies of TCM treatment for depression syndrome similar to Hwabyung from CNKI using terms 'depression' and 'qi stagnation transforming into fire'. Using extracted data, characteristics of clinical research, herbal medicine, and acupuncture treatment used in the clinical research and their effects were systematically reviewed. Results: Symptoms of 'qi stagnation transforming into fire' were most similar to those of Hwabyung. Nine articles were selected from a total 258 articles. Most of them used DSM-IV or CCMD-3 for depression diagnosis. They applied 'diagnostic and efficacy guidelines for TCM diseases and syndromes' for pattern diagnosis of 'qi stagnation transforming into fire'. Danzhixiaoyao-san and Jiaweixiaoyao-san were found to be effective when they were used alone or in combination with antidepressants. Acupuncture treatment also showed remarkable effect on LR3, HT7, LI4, PC6, GV20 when it was used alone or in combination with antidepressants. However, careful interpretation is required because a small number of studies are included.Conclusions: 'Qi stagnation transforming into fire' seemed to have symptoms similar to Hwabyung. However, further research is needed to determine its diseases and pattern types compared to Hwabyung. According to included studies of 'depression with Qi stagnation transforming into fire', herbal medicine and acupuncture treatment tended to be effective in relieving depressive symptoms. However, more discussion is required for future application of herbal medicine and acupuncture for treating Hwabyung.

길랑-바레 증후군의 한방치료에 관한 고찰 - 중의학 저널을 중심으로 - (A Literature Study on Treatment of Guillain-Barre Syndrome Based on Traditional Chinese Medicine Journals)

  • 김형중;이은주;이선행;장규태
    • 대한한방소아과학회지
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    • 제29권3호
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    • pp.21-31
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    • 2015
  • Objectives : The purpose of this study is to analyze Korean medicine treatment of guillain-barre syndrome based on TCM (Traditional Chinese Medicine) Journals. Methods : 12 control studies and 28 case studies in CNKI (China National Knowledge Infrastructure) were selected for analysis. Results and Conclusions : 1. In control studies, most studies have studied western medicine (Control) versus western medicine + TCM (Intervention group). The intervention group had significantly better results than that of the control group. 2. In case studies, syndrome differentiations related to dual deficiency of qi and blood are common. Every syndrome differentiations has deficiency syndrome. 3. The most commonly used acupoints are LI11, ST36, LI4 and GB34. 4. The most commonly used meridians are large intestine meridian and stomach meridian.

A Review of Current Clinical Research on Herbal Monotherapy for Coronavirus Disease-19 (COVID-19)

  • Jee Won Shon;Do Kyung Han;Won Gun An
    • 대한한의학회지
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    • 제44권4호
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    • pp.193-207
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    • 2023
  • Objectives: The purpose of this study was to evaluate the effectiveness and safety of traditional herbal medicine as a stand-alone treatment group through major English databases due to the lack of RCTs in Korea, and to provide a review of the herbal interventions used. Methods: Using four databases (Pubmed, EMBASE, OASIS, RISS), combination of words such as "Coronavirus" "RCT" "Herb" "Decoction" "TCM" were used. RCTs using herbal medicines to treat coronavirus were searched. Final 4 studies were selected by two authors according to inclusion and exclusion criteria. Results: A total of 1,435 patients were studied. The Chinese herbs used in the treatment group were Shengmai Yin, JingYinGuBiao granules, Jinhua Qinggan granules, and Bufei Huoxue capsules. The intervention group showed greater attenuation of pneumonia lesions on CT. Also, improvement in 6-min walk distance (6MWD), and negative conversion rate in treatment group were reported. Furthermore, scores on the Fatigue Assessment Inventory (FAI) were lower in the herbal group than in the placebo group. The median time to recovery of COVID-19 related symptoms was shorter in TCM group compared to the control group. Reported adverse effects were diarrhea, liver dysfunction, and excessive menstruation, and two papers did not mention side effects in detail. Conclusion: Herbal medicine alone can increase the conversion rate of viral negativity and relieve COVID-19 related symptoms without significant adverse effects.

자궁근종의 치료에 대한 고찰 -2010년 중국내 발표 논문 중심으로- (The Study on the Treatment of Leiomyoma - Focusing on the Papers Published in 2010 within China -)

  • 백영주;김명동
    • 대한한방부인과학회지
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    • 제24권1호
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    • pp.109-131
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    • 2011
  • Objectives: This study aims to search the clinical cases that treated leiomyoma through the traditional Chinese medicine, to understand the study trend on leiomyoma in China, and to clairfy the cause of leiomyoma and its treatment by the oriental medicine herbs. Methods: We searched the key word "leiomyoma" in the China National Knowledge Infrastructure (CNKI)[http://www.cnki.net], and narrowed its searching area to the papers published in the year 2010. Of 720 study papers, we chose 21 clinical papers on the leiomyoma, and studied the patient case, treating method, result of treatment, and checked the category, cause, treatment method of leiomyoma. Results: The results are shown in the Table 1-3. Conclusions: Leiomyoma is categorized in the traditional Chinese medicine as both lump occuring inside the body and stony abdominal lump. The main cause of leiomyoma is qi-stagnation and blood stasis, essence deficiency and pathogen affluence. The treatment method is used by activating blood and resolving stasis but harmonizing the spleen and stomach to prevent damaging healthy qi. The development herbal medicine of treating leiomyoma is Gyehongbyeolgaphwan, Gyejibongnyeonggyonang, Gungryusogyonang, Angonpyoen etc. In treating leiomyoma, the herbs were much used to regulate qi as Baekbokryung, Danggwi, Baekchul, Doin, Moryeo, Achul, Mokdanpi etc. Traditional Chinese Medicine(TCM) treatment of leiomyoma has efficiency of improve symptom but low ratio of complete recovery.

Good Agriculture Practice (GAP) and Sustainable Resource Utilization of Chinese Materia Medico

  • Wenyuan Gao;Wei Jia;Hongquan Duan;Luqi Huang;Xiaohe Xiao;Peigen Xiao;Peak, Kee-Yoeup
    • Journal of Plant Biotechnology
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    • 제4권3호
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    • pp.103-107
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    • 2002
  • The Good Agriculture Practice (GAP) program, being established in China, is an optimal way for the sustainable utilization of the medicinal plant and animal resources. Most frequently used Chinese materia medica will be mainly produced from the GAP bases in the future. To assure the successful operation of GAP program, standard operating procedure (SOP) should be implemented for specific plants or animals. Both GAP and SOP include the requirements in many aspects from the ecological environment of cultivation place, germplasm and varieties, seedling and transplant, fertilization, irrigation, and field care, to harvest and process, package, transport and storage. As a complex system, GAP demands strong commitment from the pharmaceutical industry, local administrative involvement, long term R&D support, and years of time of development before a satisfactory result can be achieved.

소아비만의 효과적인 접근을 위한 문헌적 고찰;1996${\sim}$2007년 국외 논문을 중심으로 (A Literature Review : More Effective Apporoach for Childhood Obesity;Based on International Papers Published from 1996 to 2007)

  • 신미숙;안혜림
    • 한방비만학회지
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    • 제7권1호
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    • pp.9-22
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    • 2007
  • Objectives : This study was designed to collect the latest papers and to find more effective approach for childhood obesity. Methods : We searched 107 papers in English from Pubmed(www.ncbi.nlm.nih.gov) and selected 52 in favor of our study. In addition to that, we searched 29 papers in Chinese from www.cnki.net. Results are as follows. Results and Conclusions : There are not completely new treatments for childhood obesity. Instead of that, many studies aimed for prevention through family education, nutrition education, and exercises education. Specially, because some diseases including hypertension, diabetes and heart disease are connected with obese children, medication can be prescribed optionally. In that case, their mental health must be laid emphasis. And in China, TCM(Traditional Chinese Medicine) is very common treatment for childhood obesity. Acupuncture, herb medication and manual therapy could be used usefully. It is suggested that above latest treatments can be combined with Korean traditional treatments method in treating obese children.

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경증 및 아임상 우울증의 중의학 임상연구 동향 분석 - China National Knowledge Infrastructure를 중심으로 - (The Analysis of Clinical Trial Research Trend on Mild and Sub-clinical Depression in Traditional Chinese Medicine - using China National Knowledge Infrastructure Database -)

  • 고유미;이시우;김상혁
    • 대한예방한의학회지
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    • 제19권1호
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    • pp.47-59
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    • 2015
  • Objective : The purpose of this study was to analyze the trend of clinical research on 'mild and sub-clinical depressions' in China. Method : The journal search was performed using China National Knowledge Infrastructure(CNKI). Our inclusion criteria were as follows: TCM clinical trials for mild, sub-clinical, early stage of depression. Exclusion criteria were the following: non-TCM clinical trials, disease-associated depression related clinical trials. Results : We included 16 papers in this study. 1. In this study, we realized there have been several mild and sub-clinical depressions related clinical trials conducted in the field of TCM. 2. The result of 10 Journals used the Hamilton Depression Rating Scale for diagnosis and assessment criteria of mild and sub-clinical depressions. 3. The selected journals categorized by various interventions, such as, herbal medicine(7), acupuncture(4), miscellaneous(5). 4. Also, 7 Journals showed the significant improvements in patients with mild and sub-clinical depressions by TCM interventions, and 5 studies of TCM patent prescription reported that herbal medicine therapy has less side effect than the western medicine. Conclusion : Through this study, we found out that several researchers in China performed clinical trials on mild and sub-clinical depressions constantly. From the result of this study, we need to concern about the necessity of research on the mild and sub-clinical depression in Korea. Therefore, this result could be used as a meaningful reference for the design of future clinical trials.