Journal of Oriental Neuropsychiatry (동의신경정신과학회지)

The Korean Society of Oriental Neuropsychiatry (대한한방신경정신과학회)
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Analysis of Clinical Research Trends on Traditional Chinese Medicine Treatment for Depression Syndrome Similar to Hwabyung: Focusing on CNKI

화병(火病) 유사 병증의 한의학적 치료에 대한 임상연구 동향분석 - CNKI를 중심으로

  • Choi, Eun-ji (Department of Korean Neuropsychiatry, Kyung Hee University Hospital at Gangdong) ;
  • Suh, Hyo-weon (Department of Clinical Korean Medicine, Graduate School, Kyung Hee University) ;
  • Kim, Jong Woo (Department of Korean Neuropsychiatry, Kyung Hee University Hospital at GangdongDepartment of Neuropsychiatry, College of Korean Medicine, Kyung Hee University) ;
  • Chung, Sun Yong (Department of Korean Neuropsychiatry, Kyung Hee University Hospital at GangdongDepartment of Neuropsychiatry, College of Korean Medicine, Kyung Hee University)
  • 최은지 (강동경희대학교병원 한방신경정신과) ;
  • 서효원 (경희대학교 대학원 임상한의학과) ;
  • 김종우 (강동경희대학교병원 한방신경정신과) ;
  • 정선용 (강동경희대학교병원 한방신경정신과)
  • Received : 2017.11.20
  • Accepted : 2017.12.16
  • Published : 2017.12.30
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Abstract

Objectives: To analyze whether a concept similar to Korean 'Hwabyung' exists in China. We investigated the status of clinical studies conducted in China for relevant diseases and trends of the traditional Chinese medicinal (TCM) treatment adopted in clinical studies. Methods: To explore the concept of a condition similar to Korean Hwabyung in China, we searched for the existence of concept and pattern that were parallel or similar to those of Hwabyung in TCM text-books and diagnostic guidelines. We searched and analyzed clinical studies of TCM treatment for depression syndrome similar to Hwabyung from CNKI using terms 'depression' and 'qi stagnation transforming into fire'. Using extracted data, characteristics of clinical research, herbal medicine, and acupuncture treatment used in the clinical research and their effects were systematically reviewed. Results: Symptoms of 'qi stagnation transforming into fire' were most similar to those of Hwabyung. Nine articles were selected from a total 258 articles. Most of them used DSM-IV or CCMD-3 for depression diagnosis. They applied 'diagnostic and efficacy guidelines for TCM diseases and syndromes' for pattern diagnosis of 'qi stagnation transforming into fire'. Danzhixiaoyao-san and Jiaweixiaoyao-san were found to be effective when they were used alone or in combination with antidepressants. Acupuncture treatment also showed remarkable effect on LR3, HT7, LI4, PC6, GV20 when it was used alone or in combination with antidepressants. However, careful interpretation is required because a small number of studies are included.Conclusions: 'Qi stagnation transforming into fire' seemed to have symptoms similar to Hwabyung. However, further research is needed to determine its diseases and pattern types compared to Hwabyung. According to included studies of 'depression with Qi stagnation transforming into fire', herbal medicine and acupuncture treatment tended to be effective in relieving depressive symptoms. However, more discussion is required for future application of herbal medicine and acupuncture for treating Hwabyung.

Keywords

References

  1. National Oriental Medical College Neuropsychology Textbook Compilation Committee. Korean Neuropsychology. Seoul. Jipmoondang. 2016:497-501.
  2. American Psychiatric Association. Diagnostic and statistical manual of mental disorders: DSM-IV. 4th ed. Washington D.C. American Psychiatric Association. 1994:846.
  3. Kim JW, Lee MS, Park DG, Kwon JH. Reliability and Validity of Structured Interview for Hwa-Byung. The Korean Psychological Association Conference. 2003;(1):296-7.
  4. Min SK. Effects of Paroxetine on Symptoms of Hwa-Byung. Clinical psychopharmacology and neuroscience. 2009;20(2):90-7.
  5. The Korean Society Of Oriental Neuropsychiatry, Hwabyung Research Center. Clinical Guidelines for Hwabyung. Seoul. Jipmoondang. 2013.
  6. Suh HW, Choi EJ, Kim JW, Chung SY. Current Trends in Intervention Studies of Hwabyung in Korean Medicine. Journal of oriental neuropsychiatry. 2016;27(4):261-74. https://doi.org/10.7231/jon.2016.27.4.261
  7. Zhou Z. Internal Medicine of Traditional Chinese Medicine. Beijing. China Press of Traditional Chinese Medicine. 2007.
  8. State Administration of TCM of China. Diagnostic and efficacy guidelines of TCM diseases and syndromes. Nanjing, China. Nanjing University Press. 1994.
  9. Chinese Psychiatric Society. The Chinese Classification of Mental Disorders. 3rd ed. (CCMD-3) Shandong, China. Shandong Publishing House of Science and Technology. 2001.
  10. Min SK, Suh SY, Cho YK, Huh JE, Song KJ. Development of Hwa-Byung scale and research criteria of Hwa-Byung. Journal of Korean Neuropsychiatric Association. 2009;48:77-85.
  11. Zhou J. Multicenter randomized controlled clinical study of Jiaweixiaoyao Capsule in the treatment of mild to moderate depression with dyndrome of qi stagnation transforming into fire. Doctoral Thesis of China Acamemy of Chinese Medical Sciences. 2013.
  12. Chen L. Clinical Study of Jiawei Xiaao Capsule in Treating 62 Cases of Moderate and Moderate Depression with syndrome of qi stagnation transforming into fire (Translated from 加味逍遥胶囊治疗62例轻中度抑郁症气郁化火证临床疗效观察). Master's thesis of Beijing University of Chinese Medicine. 2014.
  13. Ma KX. Selecting and therapeutic evaluating of an effective prescription for mild to moderate depression with anxiety. Doctoral Thesis of China Academy of Chinese Medical Sciences. 2014.
  14. Yang H. Study the therapeutic effect on Dragon Bone and Oyster shell decoction treat for Qi depression transforming into fire type and its effect on HPA Axis. Master's thesis of Gansu university of Chinese medicine. 2015.
  15. Guo YM, Liu CF. Syndrome Differentiation and Treatment of Somatoform Diseases with Depression in 78 Cases(Translated from 中医辨证治疗躯体疾病伴发抑郁78例). China's Naturopathy. 2003;11(6):52-3.
  16. Niu SY, Li N, You H, Shi SX, Liu CM. Effect of integrated therapy of Chinese and western medicine on differentiation of symptoms and signs of patients with depression. Chinese Journal of Clinical Rehabilitation. 2006;10(39):7-9.
  17. Huang X, Shi L, Sun J, Chen Y. Clinical Effect and Mechanism of Acupuncture on Depression(Translated from 针刺对抑郁症的临床疗效及作用机制). Information on Traditional Chinese Medicine. 2013;30(4):68-9.
  18. Liu XF, Feng J, Shi ZY, Wang XP. Acupuncture Adjuvant Treatment Of Refractory Depression And The Safety Of Clinical Research (Translated from 针刺辅助治疗难治性抑郁症的疗效与安全性临床研究). Gansu Science and Technology. 2015;31(14):134-7.
  19. Li JM, Thomas Neuerer, Ilko Atanassov. Treatment of depression by acupuncture and moxibustion in Germany: a report of 128 cases (Translated from 在德国针灸治抑郁症128例疗效观察). Journal of Clinical Acupuncture and Moxibustion. 2004;20(10):5-7.
  20. Choi WC. The Effect of Sihogayonggolmoryeo-tang on Anxiety of Patients with Hwa-byung: Randomized, Double-blinded, Placebo-control Trial. Doctoral thesis of Daejeon University. 2015.
  21. Kim SH, Park YC, Hong KE, Kang W, Lee SR, Jung IC. The effect of Bunsimgi-eum on Hwa-byung: randomized, double blind, placebo controlled trial. Journal of Ethnopharmacology. 2012;144(2):402-7. https://doi.org/10.1016/j.jep.2012.09.029
  22. Jung IC, Lee SR, Park YC, Hong KE, Koo YS, Jo JY, An JJ, Kang WC, Kim JW, Choi SM. The Effect of Sa-am Acupuncture Treatment for Major Symptom of Hwa-byung: A Preliminary Study. Journal of Oriental Neuropsychiatry. 2007;18(1):79-94.
  23. Choi WJ, Lee SG, Son IB, Sun SH. The effects of Sa-am Acupuncture Simpojeongkyeok Treatment on Hwa-byung : Randomized, patient-assessor blind, placebo-controlled acupuncture, pilot clinical trial. Journal of Oriental Neuropsychiatry. 2011;22(2):1-14. https://doi.org/10.7231/JON.2011.22.2.001
  24. Lee GE, Kim NK, Kim HY, Kang HW. The Effects of Acupuncture Treatment on Hwa-byung patient s Insomnia: Patient-assessor blind, Randomized, Placebo-controlled Clinical trial. Journal of Oriental Neuropsychiatry. 2012; 23(1):31-48. https://doi.org/10.7231/JON.2012.23.1.031
  25. Lee SH. A Study on the "HWA-BYUNG" (Anger Syndrome). Journal of Korea General Hospital. 1977;1(2):63-9.
  26. Park JH, Min SK, Lee MH. A Study on the Diagnosis of Hwabyuing. Journal of Korean Neuropsychiatric Association. 1997;36(3):496-502.
  27. Kim JW, Chung SY, Suh HU, et al. The Characteristics of Hwa-byung patients Based on Hwa-byung Epidemiologic Data. Journal of Oriental Neuropsychiatry. 2010;21(2):157-69.