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Prevalence of peripheral arterial disease(PAD) used by edinburgh claudication questionnaire among the elderly people in rural communities (일부 농촌지역 노인들에서 Edinburgh 파행 설문지를 이용한 말초동맥질환 유병률)

  • Son, Ji-Yeon;Kim, Gui-Yeon;Lee, Jong-Young;Kim, Doo-Hie
    • Journal of Preventive Medicine and Public Health
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    • v.28 no.2 s.50
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    • pp.364-372
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    • 1995
  • Peripheral arterial disease(PAD) is a major health problem in the elderly population, so prevalence of PAD is investigated using Edinburgh claudication questionnaire. Subjects were over 65 years old in the kyeongsan county. The prevalence of PAD was 9.0% in total population(8.5% in men, 9.3% in women). definite claudication was 3.9%, atypical claudication was 5.1%. and, grade 1 was 4.4%, grade 2 was 4.6%. The prevalence of PAD was increased with age but not statistically significant. There was no difference of PAD by gender and smoking. PAD was significantly associated with systolic blood pressure positively. But, unexpectedly, PAD was significantly associated with BMI negatively. PAD are important elderly health problem in the our country. So the etiology and preventive methods of PAD will be researched on our country population.

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Numerical Modeling of Wave-Type Turbulent Flow on a Stepped Weir (계단형 보에서의 파형 난류 흐름 수치모의)

  • Paik, Joongcheol;Lee, Nam-Ju;Yoon, Young Ho
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.37 no.3
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    • pp.575-583
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    • 2017
  • Various types of flow patterns around the stepped weir and spillway, such as the skimming flow over such structures and the wave-type flow with a standing undular hydraulic jump and roller downstream of the structures, are developed in open channels. Unsteady three-dimensional numerical simulations are carried out using a hybrid RANS-LES turbulence modeling approach and the volume of fluid method for resolving free surface fluctuations to represent the turbulent flow including the skimming flow and wave-type flow over a stepped weir installed in a rectangular channel. The comparison of numerical results with an existing experimental measurement reveals that the present numerical simulations reasonably well reproduce the turbulent flow passing the stepped weir, in terms of time-averaged velocity profiles at selected locations downstream of the weir, flow topology characterized by the wave-type and skimming flows, the maximum height and length of the standing wave and the length of reattachment of recirculating zone. The numerical result further elucidates the distinct flow behaviors of the wave-type and skimming flow by presenting instantaneous intense variations of free surface and velocity vectors, the distributions of Reynolds shear stress and turbulent kinetic energy and three-dimensional complex features of coherent structures and total pressure distribution.

Effect of NPK Fertilization on the Yields and Effective Components of Chrysanthemum boreale M. (산국의 수량과 유효성분에 대한 NPK의 효과)

  • Yang, Min-Suk;Jung, Yeun-Kyu;Sohn, Bo-Kyoon;Cho, Ju-Sik;Lee, Seong-Tae;Kim, Pil-Joo;Lee, Kyung-Dong
    • Applied Biological Chemistry
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    • v.46 no.2
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    • pp.134-139
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    • 2003
  • To establish the fertilization condition to increase the productivity of Chasanthemum boreale M. with high quality, the effects of three nutrients (N, P, K) on the yields and the effective components were investigated in the pot scale. NPK was applied by chemical fertilizers with $(N-P_2O_5,-K_2O=250-160-160\;kg/ha)$ as a main treatment, and NP $(N-P_2O_5,-K_2O=250-160-160\;kg/ha)$, NK $(N-K_2O =250-160\;kg/ha)$, and PK $(P_2O_5K_2O=160-160\;kg/ha)$ treatments were settled as comparison. Dry yields of C. boreale M. was increased significantly to 4 fold higher by nitrogen. Nitrogen increased apparently plant growth and inorganic nutrient uptake. In the flower, which is most useful and edible part as a herbal medicine, main amino acids were glutamic acid and aspartic acids, and the total content was increased significantly by three elements of application. In addition, the content of cumambrin A, which is known to have the effect of blood-pressure reduction, was increased source to 6.2 times by nitrogen higher than that in PK treatment. Potassium was more effective in biosynthesis of cumambrin A than phosphorus, but the biological pathway was not clear, still.

A Study on the Characteristics of Carbon Dioxide Emissions from Gasoline Passenger Cars (국내 휘발유 승용차의 CO2 배출 현황)

  • Lyu, Young-Sook;Ryu, Jung-Ho;Jung, Sung-Woon;Jeon, Min-Seon;Kim, Dae-Wook;Eom, Myung-Do;Kim, Jong-Choon
    • Transactions of the Korean Society of Automotive Engineers
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    • v.15 no.2
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    • pp.58-64
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    • 2007
  • As the concerns regarding global worming were increased, the pressure of greenhouse gas(GHG) emission reduction on mobile source was also increased. Carbon dioxides contribute over 90% of total GHG emission and the mobile source occupies about 20% of this $CO_2$ emission. Therefore automotive exhaust is suspected to be one of the major reasons of the rapid increase in greenhouse effect gases in ambient air. In this study, in order to investigate $CO_2$ emission characteristics from gasoline passenger cars(PC), which is the most dominant vehicle type in Korea, 106 vehicles were tested on the chassis dynamometer. $CO_2$ emissions and fuel efficiency were measured. The emission characteristics by displacement, gross vehicle weight, vehicle speed and CVS-75/vehicle speed mode were discussed. Test modes were vehicle speed modes and CVS-75 mode that have been used to develop emission factors and to regulate for light-duty vehicle in Korea. It was found that $CO_2$ emissions showed higher large displacement, heavy gross vehicle weight, low vehicle speed and CVS-75 mode than small displacement, light gross vehicle weight, high vehicle speed and vehicle speed mode, respectively. From these results, correlation between $CO_2$ emission and fuel efficiency was also determined. The results of this study will contribute to domestic greenhouse gas emissions calculation and making the national policy for climate change.

Relationship between Hydrochemical Variation of Groundwater and Gas Tigtness in the Underground Oil Storage Caverns (지하원유비축기지 공동주변 지하수의 수질화학적 변화와 기밀성과의 관계)

  • Jeong Chan Ho
    • The Journal of Engineering Geology
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    • v.14 no.3 s.40
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    • pp.259-272
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    • 2004
  • The purpose of this study is to investigate the effect of hydrochemical variation of groundwater on the gas tigtness in an unlined oil storage cavern. The groundwater chemistry is greatly influenced by the seawater mixing, the water curtain and the dissolution of grounting cements. The chemical composition of groundwater greatly varies ac-cording to both the location of monitoring wells and the sampling period. Most of groundwater shows alkaline pH and high electrical conductivity. The chemical types of groundwater show the dominant order as follows : Na-Cl type > Ca-Cl type > $Ca-HCO_3(CO_3)$ type. Thermodynamic equilibrium state between chemical composition of groundwater and major minerals indicates that carbonate minerals except clay minerals can be precipitated as a secondary mineral. It means that the secondary precipitates can not greatly exerts the clogging effect into fracture aperture in rock mass around oil storage cavern. The content of total organic carbon (TOC) shows a slightly increasing trend from initial stage to late stage. The $EpCO_2$ was computed so as to assess the gas contribution on the $CO_2$ in groundwater. The $EpCO_2$ of 0$\~$41.3 indicates that the contribution of oil gas on $CO_2$ pressure in groundwater system can be neglected.

The Effect of Community-based Health Intervention Program to Improve Metabolic Disease in Jeju Island (제주 지역주민기반 대사성질환 개선 프로그램 중재 효과)

  • Kim, Woo Jin;Kim, Sang Hoon;Park, Shin Young
    • Korean Journal of Clinical Laboratory Science
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    • v.50 no.3
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    • pp.297-303
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    • 2018
  • This study investigated the effect of community-based health intervention program to improve metabolic disease in Jeju island. There were 50 obese local residents in the experimental group (body mass index, $BMI{\geq}25kg/m^2$). They participated in cooking therapy with nutrition education (4 times), exercise program with proprioceptive neuromuscular facilitation (PNF) and stretching training (9 times), and alternative medicine program with healing touch massage (3 times) during a 3-week period. To evaluate the effectiveness of the program, body composition, blood lipid profiles, blood glucose, and waist circumference were assessed before and after the intervention program. After the program, the value of total cholesterol (TC), glycosylated hemoglobin (HbA1C), diastolic blood pressure, percent body fat, and waist circumference were decreased, and became the normal value. Especially, HbA1C, percent body fat, and waist circumference were significantly decreased (P<0.001) in the experimental group, while HbA1C, percent body fat, and waist circumference were significantly increased (P<0.001) in the control group (N=50), who had no intervention. Our results suggest that metabolic syndrome associated markers need intervention program for improving them. In conclusion, although this study did not analyze the effect of the health intervention program and cooking therapy separately, considering the result of this 3-week, short term program, the effect will be more profuse if cooking therapy and exercise program were performed concurrently.

QR code as Interactive Marketing Communication Media : Focused on Technology Acceptance Model (인터랙티브 마케팅커뮤니케이션 매체로써 QR코드 이용에 관한 연구 : 기술수용모델을 중심으로)

  • Shin, Dong-Hee;Chang, Woo Sung
    • The Journal of the Korea Contents Association
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    • v.13 no.3
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    • pp.76-86
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    • 2013
  • This study examined users' acceptance process with the QR code as an interactive marketing communications tool. We collected total 200 survey data and 181 questionnaires among them were used for the analysis during for five days, from 9 to 13 in May 2011. The first research question of this study examined the relationship among subjective norms, perceived usefulness, perceived ease of use, attitudes, and intention to use through the structural equation modeling analysis. The result of the first research showed that subjective norms about the use of QR code affect intention to use via perceived usefulness, and also directly influence on it. The perceived usefulness has the biggest impact on the intention to use. The research question 2 was to look at the condition effect with the presence of experience. As the analysis result of the second research question, the relationships between subjective norms and perceived usefulness are not different whether or not groups experience QR code, and both groups appeared to have had significant impact. Whereas the relationship between subjective norms and intention to use showed a significant influence on the population that has the experience with the QR code. In order to encourage use of the QR code, therefore, we will need to highly impress on users subjective norms which are ambient pressure on the use of QR code and positively offer marketing strategy which gives users the opportunities to get experience with the QR code.

PCR-SSCP of Serum Lysozyme Gene (Exon-III) in Riverine Buffalo and Its Association with Lysozyme Activity and Somatic Cell Count

  • Sahoo, Nihar Ranjan;Kumar, Pushpendra;Bhushan, Bharat;Bhattacharya, T.K.;Sharma, Arjava;Dayal, Sanker;Pankaj, Prabhat Kumar;Sahoo, Monalisa
    • Asian-Australasian Journal of Animal Sciences
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    • v.23 no.8
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    • pp.993-999
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    • 2010
  • Serum lysozyme gene is one of the important genes influencing the immune system as its product can cause lysis of bacterial cell wall by cleaving the peptidoglycan layer. The present investigation on the serum lysozyme gene of Indian riverine buffalo was undertaken with the objectives to identify and characterize single nucleotide polymorphic patterns by PCR-SSCP method as well as to study the effect of different genotypes on serum lysozyme activity and somatic cell count. A total of 280 animals comprising four different famous bubaline breeds (Murrah, Mehsana, Surti and Bhadawari), spread over six different farms across the country were used for this study. A 276 bp (partial intron 2, complete exon 3 and partial intron 3) fragment of lysozyme gene was screened for polymorphism using the SSCP technique. Four genotypes namely AA, AB, BC and AC were observed, out of which BC genotype was found to be the most frequent. Among these three alleles, C allele (0.38) was most prevalent in these populations. Various SSCP allelic variants were cloned for sequencing and sequences were submitted to NCBI Genbank. From the alignment of the nucleotide sequences of various allelic variants, it was found that there were differences in 12 positions among the alleles, out of which maximum variation (at 8 places) was found in the intronic region. The allele A was closer to allele-C than allele-B. Allele B was phylogenetically equidistant from both of the other alleles. Mean lysozyme activity determined in serum samples of different animals of Murrah buffalo was $27.35{\pm}2.42\;{\mu}g$ per ml of serum, whereas the mean somatic cell count was $1.25{\pm}0.13{\times}10^5$ cells per ml of milk. The SSCP pattern-wise effects of various genotypes on lysozyme activity and SCC were analyzed. Although the mean values were apparently different in various genotypes, these differences were statistically non-significant. It can be concluded that the riverine buffaloes are sufficiently polymorphic with respect to serum lysozyme gene. The absence of AA genotype in Bhadawari breed of buffalo can be considered as a marker for breed characterization. The difference of four nucleotides in exon-3 indicates high selection pressure on the gene.

$pep^{27}$ and lytA in Vancomycin-Tolerant Pneumococci

  • Olivares, Alma;Trejo, Jose Olivares;Arellano-Galindo, Jose;Zuniga, Gerardo;Escalona, Gerardo;Vigueras, Juan Carlos;Marin, Paula;Xicohtencatl, Juan;Valencia, Pedro;Velazquez-Guadarrama, Norma
    • Journal of Microbiology and Biotechnology
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    • v.21 no.12
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    • pp.1345-1351
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    • 2011
  • Vancomycin therapy failure due to the emergence of tolerance in pneumococci is increasing. The molecular mechanism of tolerance is not clear, but lytA and $pep^{27}$ are known to be involved. Our aim was to evaluate the expression of both genes in vancomycin-tolerant Streptococcus pneumoniae (VTSP) strains. Eleven VTSP strains from a total of 309 clinical isolates of S. pneumoniae from 1997 to 2006 were classified according to the criteria of Liu and Tomasz. All VTSP strains were evaluated for susceptibility according to CLSI criteria, serotype by the Quellung test, and clonality by PFGE. The expressions of lytA and $pep^{27}$ were analyzed in different growth phases by RT-PCR with and without vancomycin. Eighty-two percent of VTSP strains showed resistance to penicillin, and 100% were sensitive to vancomycin and cefotaxime. The most frequent serotypes of VTSP strains were 23F (4/11) and 6B (3/11). Clonal relationship was observed in only two strains. No significant changes were observed in $pep^{27}$ expression in the three phases of growth in VTSP strains with and without vancomycin. Interestingly, $pep^{27}$ expression in the stationary phase in the non-tolerant reference strain R6 was significantly higher. However, no significant differences in lytA expression were observed between VTSP and R6 strains during the phases of growth analyzed. The absence of changes in $pep^{27}$ expression in VTSP strains in the stationary phase may be related to their ability to tolerate high antibiotic concentrations, and thus, they survive and remain in the host under the antibiotic selective pressure reflected in therapeutic failure.

Comparative Analysis on Resources Characteristics of Deep Ocean Water and Brine Groundwater (해양심층수와 지하염수 자원의 특성)

  • Moon D.S.;Jung D.H.;Kim H.J.;Shin P.K.
    • Journal of the Korean Society for Marine Environment & Energy
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    • v.7 no.1
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    • pp.42-46
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    • 2004
  • Deep Ocean Water (DOW) is formed within restricted area including polar sea (high latitude) by cooling of surface seawater and globally circulating in the state of isolation from surface seawater. Although it is not as obvious as estuaries mixing, brine ground water is mixture of recirculated seawater and ground water. Seawater having high osmotic pressure infiltrates into an aquifer which is connected to the sea. In order to clarify the characteristics of deep ocean water and brine ground water, we investigated their origins, chemical compositions, water qualities and resources stabilities. While concentrations of stable isotopes (/sup 18/O and ²H) in seawater is 0‰, those in brine ground water is on meteoric water line or shifted toward oxygen line. It means that origin of brine ground water is different than that of deep ocean water. The ions dissolved in seawater (Na, Ca, Mg, K) are present in constant proportions to each other and to the total salt content of seawater. However deviations in ion proportions have been observed in some brine ground water. Some causes of these exception to the rule of constant proportions are due to many chemical reactions between periphery soil and ground water. While DOW has a large quantity of functional trace metals and biological affinity relative to brine ground water, DOW has relatively small amount of harmful bacteria and artificial pollutants.

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