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Hypocholesterolemic Effects of Green Tea in Cholesterol-Fed Rats (고 콜레스테롤 식이 투여 흰쥐에 있어서 녹차의 콜레스테롤 저하 효과)

  • 진현화;양정례;정종화;김양하
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.33 no.1
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    • pp.47-51
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    • 2004
  • Green tea, which is high in polyphenols, is thought to have hypocholesterolemic effects. The present study was performed to further elucidate the hypocholesterolemic actions of green tea, specially the catechin and (-)-epigallocatechin gallate (EGCG) for their effects on the diet-induced hypercholesterolemia in rats. Male Sprague-Dawley rats were fed with green tea-free diet (control), diets containing 4% green tea powder (GTP), 1.0% green tea catechin (catechin) or 0.5% epigallocatechin gallate (EGCG) for 7 wks. All diets that were provided green tea contained approximately 0.5% EGCG Hypercholesterolemia was induced by adding 1% cholesterol and 0.5% cholic acid to all diets. There were no differences in food intake among groups. The green tea treatments showed significant improvement in the serum levels of total cholesterol, LDL-cholesterol, triacylglycerides and atherogenic index in the following order; EGCG>Catechin>GTP (p<0.05). The serum HDL-cholesterol level was highest in the EGCG-treated group. The catechin or EGCG diet up-regulated by 5 times the enzyme activity of hepatic cholesterol 7$\alpha$ -hydroxylase (CYP7Al) compared to control diet (p<0.05). Hepatic CYP7Al mRNA level paralleled tile increases in the CYP7Al activity. These results suggest that the EGCG in the green tea may account for the hypocholesterolemic effect by the induction of CYP7Al gene expression.

The Role of Trivalent Chromium as a Supplement (3가 크롬의 보조제로서의 역할)

  • 박형숙;강영희
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.33 no.4
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    • pp.762-768
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    • 2004
  • Chromium has been known to be involved in the glucose metabolism, and hence the utilization of cellular glucose is impaired in the chromium deficiency. Chromium has been recognized as an essential nutrient since the finding of low-molecular-weight Cr-binding substance (LMWCr) as a biological modifier of insulin action. Clinical chromium deficiency associated with glucose intolerance that respond to the administration of chromium. The major impediment to the use of orally administered chromium is poor absorption of trivalent chromium in its inorganic form. Trivalent chromium is more available in yeast md, more recently, as chromium picolinate for oral absorption. The widespread use of these supplements has resulted in controversy regarding chromium's role as a nutrient, its use for treatment of insulin resistance, and its potential toxicity. Most recent evidence strongly supports tile conclusion that there is little fear of toxic reactions from chromium consumption. This report reviews the evidence for the potential toxicity of chromium supplements in contrast with its usefulness as a nutrient or therapeutic agent in the treatment or prevention of insulin resistance.

Effects of Combined Treatment of Gamma Irradiation and Addition of Rosemary Extract Powder on Ready-to-Eat Hamburger Steaks: I. Microbiological Quality and Shelf-life (감마선 조사와 로즈마리 추출분말 병용처리가 즉석 햄버거 스테이크에 미치는 영향: I. 미생물학적 특성 및 저장성)

  • 오상희;김장호;이주운;이유석;박경숙;김종군;이효구;변명우
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.33 no.4
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    • pp.687-693
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    • 2004
  • The objective of this study was to evaluate the combined treatment effect of gamma irradiation and rosemary extract powder on ready-to-eat hamburger steaks. After irradiation at 5, 10 and 20 k㏉, hamburger steaks manufactured with rosemary extract powder (200 and 500 ppm) were stored at 5$^{\circ}C$ for 4 months and at 3$0^{\circ}C$ for 3 weeks. Total aerobic bacteria count of the ready-to-eat hamburger steak was approximately 5 log CFU/g level. All doses of gamma irradiation were effective in reducing the population of total aerobic bacteria and coliform bacteria in hamburger steaks. In hamburger steaks irradiated at 20 k㏉, tile microbial growth was not observed during storage. The shelf-life of hamburger steaks were determined by microbiological counts of 10$^{6}$ ∼10$^{7}$ CFU/g and those of the steaks irradiated at 0, 5 and 10 k㏉ were ranged among 14, 28∼42 and 98∼112 days, respectively. The shelf-life of both irradiated hamburger steaks added with 500 ppm rosemary extract powder at 5 and 10 k㏉ was extended more 14 days than non-added sample. Results suggested that both gamma irradiation and rosemary extract powder may improve the shelf-stability of ready-to-eat ham-burger steak. However, when the storage temperature was abused (3$0^{\circ}C$), the rosemary extract powder had not sufficient effect on the shelf- stability of hamburger steaks.

A Study on the Standardization of Kimchi for the Children -The Proper Red Pepper Powder for Children대s Kimchi- (어린이 김치 표준화에 대한 연구 -어린이 김치에 적합한 고추가루-)

  • 송영옥;빈성미;문정원
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.25 no.6
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    • pp.893-898
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    • 1996
  • This study is a continuous work for the standardization of children's kimchi preparation. In order to find out the proper red pepper powder for children's kimchi, four kinds of red pepper powder(A, B, C, D) sold in Kyungsang province were used as samples. The proximate composition, color value, capsaicinoids concentration and sugar content in four kinds of the red pepper powder were determined, and sensory evaluation of kimchi Prepared with those was carried out for different fermentation times. Moisture contents of red pepper powder A, B, C and D were in the range of 11.59~13.48%. Lipid and ash contents of samples were in the range of 7.59~8.39% and 4.34~7.45%, respectively. In comparision of color values measured by a Hunter colorimeter, red pepper powder A showed the highest value for a and b values. Also A showed the brightest color as measured in ASTA color and L value. Capsaicin concentration of D and dihydrocapsaicin concentration of C were found to be the highest among the sanlples. The capsaicin equivalent was in tile order of D>C>A>B. The content of total sugar was in the order of B>A>D>C. In the sensory evaluation of children's kimchi prepared with four kinds of red pepper powder, the color and total acceptability of kimchi prepared with A were found to be the best. The results of sensory evaluation between kimchi prepared with A and school supplied kimchi showed that the former was better. And the composition of A red pepper powder was as follows: capsaicin equivalent 24.l5mg%, total sugar content 15.79% and ASTA color value 178.2.

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Physiological Activities of Ethanol Extracts from Different Parts of Ailanthus altissima (가죽나무(A. altissima) 부위별 에탄을 추출물의 생리활성)

  • Lee, Yang-Suk
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.36 no.4
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    • pp.389-394
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    • 2007
  • The study was carried out to optimize the electron donating ability (EDA), superoxide dismutase (SOD)-like activity, nitrite scavenging ability, and the inhibitory activities of xanthine oxidase and tyrosinase of Ailanthus altissima ethanol extracts from roots, stems and leaves. The EDA of the roots and stem extracts were 64.04% and 63.27% at $1,000{\mu}g/mL$, respectively. The SOD-like activity of the leaves extract was the highest (50.00%) at $1,000{\mu}g/mL$. The nitrite scavenging ability of the leaves extracts was over 98% at pH 1.2 and 3.0. The xanthine oxidase inhibitory rates of the extracts were $93.62%{\sim}95.40%$ and the tyrosinase inhibitory rate of the roots was the highest (62.01%) at the concentration of $1,000{\mu}g/mL$. These results indicated that the roots extract showed the highest EDA and tyrosinase inhibition, while the leaves extract had tile highest SOD-like activity and nitrate scavenging ability.

A Study of Stress Factors Experienced by the Hospitalized Patients (입원이 불안감(Stress)으로서 환자에게 미치는 영향에 관한 일 연구)

  • 최옥신
    • Journal of Korean Academy of Nursing
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    • v.5 no.1
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    • pp.93-111
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    • 1975
  • As the hospitalized patients will be facing new stress situation due to change of his environment from home to hospital it will be very important to understand the psychological stress experienced by hospital patients not only for helping patients in the process of recovery from illness but also fulfil1ing the objective of comprehensive nursing care by understanding the needs of the patients. There is no doubt that it would be very helpful for treatment of patients as well as for improvement of nursing care if we know more about psychological needs of patients and give them adequate support to meet these needs. The study to find out the causes and degree of stress events experienced by hospitalized patients, with the objective of instituting improvement of nursing care program based on the needs of patients, was conducted during the month of September 1974 with 60 patients randomly selected from those admitted to medical and surgical wards at Yonsei Medical Center in that period The questionnaire form included 36 questions which are considered to be stress events for hospital patients, and was devide into five areas namely, such events related to 1) disease itself, 2) hospital environment, 3) nursing care and treatment, 4) communication and human relations, and 5) family and economic problems. The results of the study were as follows: 1. It was confirmed that hospitalization considered to be a stress producing factor and most patients perceived the admission to hospital as a stress factor. 2. According to the rating scale, it was found that degree of perceived stress shows a variation according to the source of stress producing event. 3. No significant differences in the mean values were observed statistically with the perceived stress levels according to demographic and other variables of patients related to hospitalization. 4. Among the questions related to disease itself, "Admission for surgery" was perceived most frequently as a stress event (97.14%) by patients. 5. With regard to the questions related to hospital environment, "death of the patient room-mate" was the most serious stress event perceived by patients (90%) and "living with hospital regulations"was considered to be less serious stress event (23.33%). 6. As for the questions related to nursing care and treatment, "limitation of freedom" was perceived as a stress factor most frequently (70.91%) by the patients and "worry for wrong treatment" turned out to be less frequent stress event (50.0%). 7. As for the questions related to communication and human relations, "difficulty to meet doctors when wanted"appeared to be the most frequent stress event by the respondents (75.86%) , followed by "no explanation about treatment or examination"(75.0%) and "no explanation about nursing care procedures"(71.66%). 8. With regard 111 tile questions related to family and economic problems, "inadequate finances for family living due to hospitalization"and "high cost of hospitalization" were the most frequent cause of stress mentioned by the patients. (80.0%). 9. As a result of application of the stepwise regression analysis, it was found that about 89% was explained by those events associated with disease itself, hospital environment and family and economic problems. By adding those events related to "nursing care and treatment" and "communication and human relation", 100% of stress associated with hospitalization was explained.

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COMPARATIVE STUDY ON BODY TEMPERATURE CHANCE OF NEWBORN INFANTS IN GENERAL CRIB AND ELECTRIC-HEAT CRIB (일반침대와 가온침대에 있는 신생아의 체온변화에 관한 비교연구)

  • 박영숙
    • Journal of Korean Academy of Nursing
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    • v.4 no.1
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    • pp.95-106
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    • 1974
  • The Purpose of this study was to observe the body temperature changes of newborn infants in general crib and electric heat crib after birth for the period required to reach the optimum body temperature. Forty-seven newborn infants who were delivered at Seoul National University Hospital during the period from June 12 to September 13, 1973 were chosen as Subjects for this study. The criteria for the choice of subjects were the babies with normal spontaneous delivery; body weight 2.5kg and over at birth; Apgar so ore seven and over and gestation period over thirty-six weeks. Of these subjects, by random sampling thirty-one newborn infants were placed in the general crib and sixteen in the electric-heat crib. The rectal body temperature of these newborn infants were taken and recorded at fifteen-minute interval for the first one hour period after birth, at thirty minute interval for the next two hours and at one hour interval for the remaining period up to eight hours. The results of the study were as follows: 1. The mean body temperature of the newborn infants on admission to nursery ranged from 98.7℉. to 99℉. irrespective of the body weight and the room temperature. 2. There was a significant difference in the body temperature changes of the newborn infants as a total between the general crib and the electric-heat crib from three to eight hours after birth. It was found that the body temperature of the newborn infants in the electric-heat crib was significantly higher than that of the newborn infants in the general crib. 3. In comparison with the body temperature changes of the newborn infants in the general crib, the newborn infants in the electric- heat crib exhibited significantly higher body temperatures in all three body weight groups; from four to eight hours after birth in the 2.5-2.9kg body weight group; from three to seven hours after birth in the 3.0-3.4kg body weight group; from two and half to six hours after birth in the group with body weight over 3.5kg. 4. Time required to reach 98℉. of body temperature was four hours in the 3.5-2.9kg body weight group, three hours in the 3.0-3.4kg. body weight group and two and half hours in the group with body weight over 3.5kg in the electric- heat crib. In the general crib, it took over eight hours in the 2.5-2.9kg body weight group and five hors in both the 3.0-3.4kg and over 3.5kg body weight group to reach 98℉ of body temperature. 5. The lowest mean body temperature of newborn infants in both general and electric- heat crib appeared in forty-five minute after birth and the temperature ranged from 96.4℉ to 96.5℉. 6. The mean body temperature of the newborn infants in the general crib was increased as the room temperature. 7. The body weight, the room temperature and the time elapsed after birth fore proved to be significant factors influencing the body temperature changes of newborn infants. From tile above results, the three hypotheses were positively accepted.

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A Study on Value Orientation of Health of Rural Health Center Milieu (농촌지역 보건소 환경에 있어서의 건강가치관에 관한 일 조사연구)

  • 김순자
    • Journal of Korean Academy of Nursing
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    • v.5 no.1
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    • pp.17-30
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    • 1975
  • The concept and definition of nursing and her role have been changing in accordance with the socio-cultural factors of the initial society. At present, nursing is conceptualized as a health care profession assisting man to restore, maintain and promote health by providing knowledge, wilt strength and resources through various processes of interaction. Man′s behavior, of individual and group activities for health inclusive, is driven by the initial man′s value orientation. The purpose of this study is to investigate the value orientation regarding health of rural health center milieu in order to give data for; 1. the planning for the delivery of community nursing service, 2. the health education plan at all level of nursing care activities, and 3. the planning of curriculum for nursing education. A hundred opinion leaders among the labor population residing in rural areas (P-group), hundred and six professional nurses at rural health centers (N-group) were indirectly interviewed through questionaries. And ninety five of N-group were interviewed likewise of their perceptions of P-group (NP-group) from July 15, to October 15, 1974. The result is as follows: 1. Maintenance of health is revealed to be the most valued component for man′s happiness in all the three groups. (P-group: 7.30 S. D.=1.31), (N-group :7.84 S. D. =49), and (NP-group : 5.93 S. D. =2.28) 2. The average value score of the maintenance of health revealed significant difference by P〈.001 level between each of the three groups. (Between N-group and P-group : T= -4.07 P and NP ; T=-6.93, N and NP: T=-9.35) 3. Basic health maintenance activities necessary for maintenance and promotion of personal health were moderately valued by all the three groups, P-group ; 3.74 (S. D. =.43) , N-group: 3.52 (S. D. =.34), NP-group: 3.07 (S. D. :.55) Among the 8 categories of basic health maintenance activities, "food intake" was highly valued by P-group (mean value score; 4.00 S. D=.51) , "exercise and rest" and "personal cleanliness" was highly valued by both P-group (4.02, 4.08) and N-group (4.08, 4.22). 4. The mean value score of basic health maintenance activities revealed significant difference by P〈.001 level between each of the three groups (between P-group and N-group: T=-4, 07, N-and NP: T=-6.93, P and NP T=-9.35) 5. Among the 30 questionaries, dynamic activities for health maintenance were more valued in comparison to passive activities in an tile three groups. 6. In N-group, correlation between the value of basic health maintenance activities and the personal health status personal revealed moderate significance. Correlation between the value of basic health maintenance activities and the age revealed low significance. 7. In group, correlation between the value of basic health maintenance activities and; perception of personal health status revealed non significance, between the age and sex revealed low sign affiance, and between the educational status revealed moderate significance. Recommendations are as follows ; 1. The efforts towards alteration of value orientation concerning health in general in community nursing practice de focussed be that of family Planning. 2. In order to prepare professional nurses competent in understanding individual and group, social science and behavioral science be strength ended in planning nursing curriculum. 3. Milieu of nursing experience during nursing education be Planned to begin at simple nursing problem and move towards complex, f. e. home care towards health crisis situation in order to achieve dynamic role mastery.

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Epidemiological Study of the Communicable Disease in Kang Won Area (강원도 농어촌 지역에 발생한 급성전염병의 역학적 고찰)

  • 김성실
    • Journal of Korean Academy of Nursing
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    • v.2 no.1
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    • pp.73-85
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    • 1971
  • A epidemiological study was conducted by author on 925 official reported patients with the first grade legal communicable disease during the period from January 1969 to December 1970 in all area of Kangwon province. As the results of this study, tile following conclusion were obtained. A) Typhoid fever 1. Of all 925 patients surveyed, typhoid fever showed the highest rate as 50.7 percent. 2. Age group from 10 to 14 years old showed the highest rates 3. High epidemic period was from June to September. 4. As for the occupational distribution, unemployed showed the highest rate as 63.2 percent, followed by-21.1 percent in farmer and 9.4 percent in student. 5. Most of all patients(93.7%) were isolated in their own house 6. The morbidity rate was 16.0 per 100, 000 population and case fatality rate was 1.76 percent 7. The mean of the duration from onset to diagnosis and carnation were 11.7$\pm$7.1 days and 25.1$\pm$13, 8 days respectively. 8. Main diagnostic method was almost the clinical examination B) Dysentery 1, Of all 925 patients surveyed, dysentery showed 44.4 percent 2. Age group from 0 to 9 years old showed the highest rate 3. High epidemic period of this disease was from April to August 4. As for the occupational distribution, unemployed showed the highest rate as 73.9 percent, followed by 17.7 person in farmers and 7.0 percent in student 5. the attack rate of agricultural area was higher than of fishing area 6. The mean of the duration from onset to diagnosis and crating duration were 10.4$\pm$4.3 days and 15.7$\pm$8.8 days respectively. 7. The morbidity rate and case fatality rate were 21.8 per 100.000 population and 1.46 percent, respectively. 8. Most of all patients were isolated in own house 9. Most of all patients (97.6%) were diagnosed by the clinical examination C) Diphtheria 1. As for the age distribution, 0-4 years old group showed the highest rate as 44.4 percent followed by 27.7 percent in 5-9 years old group and 22.2 percent in 10-14 years old group 3. Epidemic season was almost in autumn, winter and spring 3. The morbidity rate was 0.96 per 100.000 population and case fatality rate was high as 26.6 percent 4. 66.6 percent of this disease was isolated in their own house and the others were admitted in hospital D) Paratyphoid fever 1. Most of all patients were attacked below 20 years old 2. Epidemic season was almost was almost in late summer 3. The morbidity rate was 0.53 per 100.000 population 4. The mean of the duration from onset to diagnosis and crating duration were 18.3$\pm$1.3 day and 13.7$\pm$0.2 day. respectively.

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Effects of Preoperative Psychological fare on Postoperative Recovery - An Exploratory Experiment - (수술 전 심리간호가 회복에 미치는 효과에 관한 실험적 연구)

  • 김조자
    • Journal of Korean Academy of Nursing
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    • v.2 no.1
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    • pp.97-113
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    • 1971
  • The purpose of this study was to investigate the preoperative anxiety of surgical patients and to observe the effects of an experimental nursing process on the incidence of vomiting, the number of analgesics used and the voiding ability of surgical patients within a 48 hour postoperative period and also the number of postoperative days in the hospital. This study me based on a sample of 51 patients who were scheduled for abdominal surgery. They were assigned alternately to experimental and control groups. Patients assigned to the experimental group were given nursing care by the writer, using an experimental nursing process. This is a process directed toward helping the patient obtain a suitable psychological state for surgery. This process was performed by use of the following steps: 1. The nurse approached the patient with interest and concern, and observed the patient's behavior to determine the presence of anxiety. 2. The nurse explored further to find out what was causing the anxiety and what was needed too relieve it. 3. The nurse listened carefully lo the patient. 4. The nurse gave an opportunity for expression of individuality. 5. The nurse showed friendliness and reassured the patient 6. The nurse gave instruction about deep berating, turing and coughing and gave an explanation of routine preoperative preparation which decreased the unknown and so decreased the patient's anxiety- The findings of this study are as follows: 7. The investigation of preoperative anxiety through observing and interviewing revealed patients were concerned about the following: a. Length of stay in the hospital 69.7% (31 cases) b. Condition unimproved o. worse 48.,8% (30 cases) c. Postoperative pain and discomfort .56.8% (29 cases) 2. The results of the study regarding the four hypothesis were as follows: a. Preoperative psychological care not reduce the number of analysis needed during the 48 hour period following surgery. b. Preoperative psychological care did not reduce the Postoperative incidence of vomiting c. Preoperative psychological care had no influence on voiding ability following surgery. d. Preoperative psychological care significantly reduced the number of postoperative days in tile hospital. The experimental nursing process proved to be successful in decreasing the length of postoperative hospitalization (improving rate of healing). This study has demonstrated further that the relief of anxiety (emotional distress) is part of the nurse's professional role. In order to be sure psychological care is given it is important to make a nursing care plan which .includes a plan for the psychological care needed by the patient. As this care is given it can be charted off by each nurse just as medication and treatments are checked after they are given.

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