• 한국응용과학기술학회지
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• 제19권1호
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• pp.19-24
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• 2002

It is a great role that the character of man or woman could be distinguished by hair on the aspect of ornament. Hair will be support of beautifulness of human being in various permanent wave by many kinds of its drugs. Hair is based upon the skin which enroll the body of high living animals and have multiple membrane structure. This study used rat and the effects of commercial permanent wave products to skin which are composed with thioglycolic acid and bases. Results are as follows. Permanent wave penetrated to 4 hours later with steady state in skins and was not significant changeable after 20hr later. In case of neutralizer with thioglycolic acid lag time and permeability coefficient in healthy skin is 3.38hr and $0.094^{\mu}g/cm^{2}$ ${\cdot}$ hr, it old skin is 3.48hr and 0.129$^{\mu}g/cm^{2}$ ${\cdot}$ hr, and it wounded skin is 4.72hr and $0.158^{\mu}g/cm^{2}$ ${\cdot}$ hr. In conclusion, lag time and permeability coefficient in old skin and wounded skin are faster than healthy skin. In vivo which was studied by general time and method of permanent wave. We notified that fine rinkle and rash of skin were changeable in the case of treating with permanent wave drugs than normal skin. We can see even rash and eruption by the naked eye.

• 한국분말재료학회지
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• 제24권6호
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• pp.489-493
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• 2017

In this study, the surface passivation process for InP-based quantum dots (QDs) is investigated. Surface coating is performed with poly(methylmethacrylate) (PMMA) and thioglycolic acid. The quantum yield (QY) of a PMMA-coated sample slightly increases by approximately 1.3% relative to that of the as-synthesized InP/ZnS QDs. The QYs of the uncoated and PMMA-coated samples drastically decrease after 16 days because of the high defect state density of the InP-based QDs. PMMA does not have a significant effect on the defect passivation. Thioglycolic acid is investigated in this study for the effective surface passivation of InP-based QDs. Surface passivation with thioglycolic acid is more effective than that with the PMMA coating, and the QY increases from 1.7% to 11.3%. ZnS formed on the surface of the InP QDs and S in thioglycolic acid show strong bonding property. Additionally, the QY is further increased up to 21.0% by the photochemical reaction. Electron-hole pairs are formed by light irradiation and lead to strong bonding between the inorganic and thioglycolic acid sulfur. The surface of the InP core QDs, which does not emit light, is passivated by the irradiated light and emits green light after the photochemical reaction.

• 한국재료학회지
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• 제22권9호
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• pp.465-469
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• 2012

This paper focuses on the after synthesis of CdTe quantum dots(QDs) in aqueous solution. CdTe nanoparticles were prepared in aqueous solution using mercaptocarboxylic acid or thioglycolic acid(TGA) as stabilizing agents. QDs emit light smaller than the nano size. The contents of the mercaptocarboxylic acid, and a kind of raw material, were revealed for a period of time. We succeeded in synthesizing a very high quality QDs solution; we discussed how to make QDs better and to keep them stabilized. TGA is known as one of the best stabilizing agents. Many papers have mentioned that TGA is a good stabilizing agent. We dramatically confirmed the state of QDs after the experiments. The QDs solution can be influenced by several factors. Different content of TGA can influence the stability of the CdTe solution. Most papers deal with the synthesis of CdTe, so we decided to discuss the after synthesis process for the stability of the CdTe solution.

• 대한화학회지
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• 제35권5호
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• pp.575-579
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• 1991

6${\beta}$-bromopenicillanic acid(4a)와 p-nitrobenzylbromide, 3-bromophthalide, chloromethylpivalate 및 1-chlorodiethylcarbonate의 반응으로 6${\beta}$-bromopenicillanates(4b~4e)을 합성하였으며, 6${\beta}$-bromopenicillanic acid(4a)와 그의 ester(4b~4e)를 thioglycolic acid와 친핵성 치환반응시켜 새로운 $\beta$-lactam계 화합물인 6-(carboxymethylthio)penicillanic acid(5a)와 그의 ester(5b~5e)를 얻었다.

• 한국응용과학기술학회지
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• 제26권2호
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• pp.103-109
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• 2009

Chemicals for cosmetics, including skin, the skin absorbs some of the research in the field of science or pharmacy recently, about the environment and the health of the heightened interest in skin absorption. Many other human attributes and absorption evaluation studies are underway in various areas. This study were used rats and carried out to find out the effects of commercial permanent wave products to skin which are composed with thioglycolic acid and bases. Results were as follows. Permanent wave penetrated to 3 hours later with steady state in skins and was not significant changeable after 20hr later. In case of neutralizer with thioglycolic acid lag time and permeability coefficient in healthy skin were 3.32hr and $0.101{\mu}g/cm^2/hr$, in old skin were 3.08hr and $0.117{\mu}g/cm^2/hr$, and in wounded skin were 3.02hr and $0.166{\mu}g/cm^2/hr$. In conclusion, lag time and permeability coefficient in old skin and wounded skin were faster than healthy skin. In vivo, We were studied to general time and method of permanent wave. We found out that fine wrinkle and rash of skin were changeable in the case of treating with permanent wave drugs than normal skin.

• Archives of Pharmacal Research
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• 제13권4호
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• pp.319-324
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• 1990

Synthesis of $\alpha$-piperidino and $\alpha$-morphelino styryl quinoxalinone 2f, 2g respectively by facile one step method is reported. The Michael adducts (3a-d) obtained by the interaction of 2-styryl-2 (1H) quinoxalinone (2) and ethylacetoacetate have been treated with resorcino and hydroxylamine separately. With resorcinol the chromones (4) are obtained whereas with ydroxylamine isoxazoles (6) are the products. Michael addition of acetylacetone to 2 leads to 3-[1'-aryl-2'-(2'-hydroxy-3'-quinoxalinyl)ethyl]-2, 4-pentanediones (5) which undergo cyclisation with hydroxylamine to give isoxazoles (7). Addition of thiopenol and thioglycolic acid to 2 gives 3-$\alpha$[$\beta$-(phenyl)-$\beta$-(plenylthio)]ethyl-2(1H)-quinoxalinone (8) and 3-$\alpha$-[$\beta$-phenyl)-$\beta$-(hydroxycarbonylmethylithio)]-ethyl-2(1H)-qui noxalinone (9) respectively. 2-Bromomethyl-2(1H)-quinoxalinone (1b) reacts with thioglycolic acid to gives S-[2 (1H)-oxoquionoxaline-3-yl-methyl] mercaptoacetic acid (10) which on cyclisation with acetic anhydride/pyridine affords 1, 2, 5, 6-tetrahydro [1, 4]thiazino[4, 3-a] quinoxaline-1, 6-dione (11).

• Bulletin of the Korean Chemical Society
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• 제3권4호
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• pp.162-165
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• 1982

The rate constants of the nucleophilic addition of thioglycolic acid to the derivatives $(H,\;p-CH_3,\;p-CH_3O,\;p-Cl,\;p-NO_2)$ of ${\beta}$-nitrostyrene were determined by ultraviolet spectrophotometry. The rate equations which can be applied over a wide pH range were obtained. Therefrom a reaction mechanism was proposed. Above pH 8.5 sulfide anion adds to the double bond (Michael type addtion). However, below pH 8.5, the neutral molecule and $HSCH_2COO^{\theta}$ add to the double bond.

• 한국의류산업학회지
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• 제4권3호
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• pp.266-272
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• 2002

This research is compared and analyzed variations of the heavy metal contents in human hairs according to treating permanent wave manipulation before and after and permanent wave agents. This is the survey of women's hairs in 19 years old. On the basis of this we would like to analyze a extend of exposing of heavy metal scientifically. Also, we would to show a basic data for the permitted limits of heavy metal to keep the healthy hair The conclusion is as follows.; Mean contents of heavy metal in hairs is 2.11 ppm (Pb), 0.25 ppm (Cd), 2.62 ppm (Ni), 256 ppm (Zn), 8.45 ppm (Cu). In reducing agents (processing lotions) of perm, 1.50 ppm (Pb), 0.03 ppm (Cd), 0.05 ppm (Ni), 15.45 ppm (Zn), 0.86 ppm (Cu) in a perm (S), 2.30 ppm (Pb), 0.05 ppm (Cd), 0.05 ppm (Ni), 13.05 ppm (Zn), 0.65 ppm (Cu) in a perm (T). In oxidizing agents (neutralizer) of perm, 1.40 ppm (Pb), 0.03 ppm (Cd), 0.09 ppm (Ni), 9.05 ppm (Zn), 0.65 ppm (Cu) in a perm (S), 1.50 ppm (Pb), 0.02 ppm (Cd), 0.16 ppm (Ni), 8.00 ppm (Zn), 0.85 ppm (Cu) in a perm (T). Mean contents of lead(Pb) didn't show significant differences according to treating cysteine perm agents, showed it according to 3 treating thioglycolic acid perm agents (p<0.05). Mean contents of cadmium(Cd) showed significant differences (p<0.001) according to 2 treating both perm agents. Mean contents of nickel (Ni) showed neither. Mean contents of zinc (Zn) showed significant differences according to 2 treating cysteine perm agents (p<0.001) and 1 treating thioglycolic acid perm agents (p<0.01). Mean contents of copper (Cu) didn't show significant differences according to treating cysteine perm agents, showed it according to 1 treating thioglycolic acid perm agents (p<0.001).

• 분석과학
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• 제8권1호
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• pp.25-32
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• 1995

구리이온(II)과 티오글리콜산의 착물인 CuRS를 HMDE(Hanging Mercury Drop Electrode)에 흡착시켜 음극으로 주사하는 흡착벗김 전압전류법으로 미량의 티오글리콜산을 정량하는 방법을 고찰하였다. 지지 전해질로는 pH 6.5 인산염 완충용액과 pH 9.5 붕산염 완충용액을 사용하였고, 최적 조건은 구리이온(II) 농도 $1{\times}10^{-4}M$, 흡착 축적 전위 -0.2V, 흡착 축적 시간 60초, 그리고 주사 속도 20mV/sec이다. 이 때 티오글리콜산의 검출 한계는 $1{\times}10^{-9}M$이다. 이 조건하에서 콜드 파마액과 제모제 속에 포함된 티오글리콜산의 함량을 구하였다.

• 한국축산식품학회지
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• 제26권4호
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• pp.503-510
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• 2006

한국인 유아에서 분리한 13개 균주를 포함한 19개 bifidobacteria 균주를 대상으로 산, 담즙산 및 산소 노출시의 생균수의 변화를 측정하였다. 내산성은 pH 4.0, 3.0, 2.0에서 2시간까지 측정하였는데, 실험 균주마다 매우 상이한 결과를 나타내었으며, 실험 균주 중에서 B. bifidum B3, B. longum D6, B. adolescentis Fl이 우수한 생존력을 나타내었다. 실험 균주를 0.2% thioglycolic acid와 0.2% oxgall이 함유된 MRS 배지에서 생장을 측정한 결과, B. bififdum B3과 B. longum D6이 담즙산에 우수한 저항성을 나타냈으며, 균종간의 경향은 관찰되지 않았다. 호기 상태에서 48시간 노출시킨 후에 생균수의 변화를 측정한 결과, 실험 균주마다 상이한 결과를 나타내었으며 상대적으로 B. bifidum과 B. longum균주들의 생존력이 우수하였다. 산, 담즙, 산소 노출에 대한 생존력은 균종간의 경향을 나타내지 않고 균주마다 상이한 결과를 나타내었는데, 실험 균주 중에는 B. bifidum B3과 B. longum D6 균주가 모두 우수한 생존율을 나타내었다. 이들 균주는 현재 시판되는 상업용 종균과 비교해서도 동등한 성적을 나타내어 상업용 종균으로서의 사용 가능성을 시사하였다.