• Title/Summary/Keyword: the standard of reference

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Comparison of Automated Breast Volume Scanning and Hand-Held Ultrasound in the Detection of Breast Cancer: an Analysis of 5,566 Patient Evaluations

  • Choi, Woo Jung;Cha, Joo Hee;Kim, Hak Hee;Shin, Hee Jung;Kim, Hyunji;Chae, Eun Young;Hong, Min Ji
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.21
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    • pp.9101-9105
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    • 2014
  • Background: The purpose of this study was to compare the accuracy and effectiveness of automated breast volume scanning (ABVS) and hand-held ultrasound (HHUS) in the detection of breast cancer in a large population group with a long-term follow-up, and to investigate whether different ultrasound systems may influence the estimation of cancer detection. Materials and Methods: Institutional review board approval was obtained for this retrospective study, and informed consent was waived. From September 2010 to August 2011, a total of 1,866 ABVS and 3,700 HHUS participants, who underwent these procedures at our institute, were included in this study. Cancers occurring during the study and subsequent follow-up were evaluated. The reference standard was a combination of histology and follow-up imaging (${\geq}12months$). The recall rate, cancer detection yield, diagnostic accuracy, sensitivity, specificity, and positive (PPV) and negative (NPV) predictive values were calculated with exact 95% confidence intervals. Results: The recall rate was 2.57 per 1,000 (48/1,866) for ABVS and 3.57 per 1,000 (132/3,700) for HHUS, with a significant difference (p=0.048). The cancer detection yield was 3.8 per 1,000 for ABVS and 2.7 per 1,000 for HHUS. The diagnostic accuracy was 97.7% for ABVS and 96.5% for HHUS with statistical significance (p=0.018). The specificity of ABVS and HHUS were 97.8%, 96.7%, respectively (p=0.022). Conclusions: ABVS shows a comparable diagnostic performance to HHUS. ABVS is an effective supplemental tool for mammography in breast cancer detection in a large population.

Effects of Mastitis on Buffalo Milk Quality

  • Tripaldi, C.;Palocci, G.;Miarelli, M.;Catta, M.;Orlandini, S.;Amatiste, S.;Di Bernardini, R.;Catillo, G.
    • Asian-Australasian Journal of Animal Sciences
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    • v.23 no.10
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    • pp.1319-1324
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    • 2010
  • The objectives of this study were to compare the effectiveness of different indicators of mammary inflammation in buffalo and to evaluate the association of the indicators with buffalo milk yield, composition, and rennet coagulation properties. This study was carried out at four buffalo farms in central Italy using a total of 50 lactating buffalo. Milk from each buffalo was tested at the beginning, middle, and end of lactation. To evaluate the relationship between mastitis markers and milk components, three classes were defined for each of the following markers: total somatic cell count (TSCC), differential somatic cell count (DSCC), and bacteriological results The regression coefficient for the reference method and the alternative method of determining TSCC was 0.81, indicating that the method routinely used to analyze buffalo milk consistently underestimated actual TSCC. The milk samples positive for udder-specific bacteria also had higher TSCC values than the samples that were negative for bacteria ($872{\times}10^3$/ml vs. $191{\times}10^3$/ml). In samples that were positive for udder-specific bacteria, polymorphonuclear leukocytes (PMN) made up greater than 50% of the cells. Moreover, only 1% of the samples in the lowest TSCC class were positive for bacteria. The correlation between TSCC and PMN was stronger (0.70), and PMN values in buffalo milk increased significantly when the TSCC class changed from low (38%) to medium and high (56% and 64%). Milk yield was negatively related to TSCC. Significant changes in lactose (4.87%, 4.80% and 4.64%) and chloride content (0.650 mg/ml, 0.862 mg/ml and 0.882 mg/ml) were also observed with increasing TSCC values. Higher TSCC was associated with impaired rennet coagulation properties: the clotting time increased, while the curd firming time ($p{\leq}0.05$) and firmness decreased. We concluded that in buffalo as in dairy cows, TSCC is a valid indicator of udder inflammation; we also confirmed that a value of $ 200{\times}10^3 cells/ml should be used as the threshold value for early identification of an animal affected by subclinical mastitis. In addition to its association with significantly decreased milk yield, a TSCC value above this threshold value was associated with changes in milk composition and coagulating properties.

A Study on Property with Ratio of Water Mixture in Hydroponic Polyurethane Waterproofing Materials (수경화성 폴리우레탄 도막 방수재의 물 혼합비에 따른 물성변화연구)

  • Park, Jin-Sang;Park, Wan-Goo;Kim, Dong-Bum;Lee, Min-Kyu;Oh, Sang-Keun
    • Journal of the Korean Recycled Construction Resources Institute
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    • v.3 no.4
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    • pp.348-354
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    • 2015
  • Urethane waterproofing materials which currently being used most commonly in the Korean domestic market have high applicability and construct layers without forming any joints, but under the influence of low temperature and low humidity, as well as the thickness of the applied layer, the curing time of this material may become extended in construction sites. To resolve these issues, a proposed method of using water-hardening type of polyurethane waterproofing materials are being developed. However, there currently lacks any standards or evaluation methods on determining an optimal mixture ratio of water for the water-hardening polyurethane waterproofing materials. Therefore, workers and construction workers are relying on their hands-on-skills and experience to determine this ratio and are not able to obtain a consistent performance quality out of these materials. Therefore, for the establishment of a board applicability of the water-hardening polyurethane waterproofing methods in construction sites, this study objectively analyzes the changes in the performance of these materials depending on the changes of the water mixture ratio and attempts to procure the optimal ratio on the basis of forming a provisionary standard. The study prepares mixtures of varying ratio(no water added, 5, 10, 15, 20, 25, 30, 40 and 50) and conducts comparative analysis respective mixtures' performances and their changes in the physical properties in an objective manner and proposes a provisional optimal value that can serve as a data base that can be used as a reference for future studies.

Comparison of the flow estimation methods through GIUH rainfall-runoff model for flood warning system on Banseong stream (반성천 홍수경보 시스템을 위한 GIUH기반 한계홍수량 산정기법 비교연구)

  • Seong, Kiyoung;Ahn, Yujin;Lee, Taesam
    • Journal of Korea Water Resources Association
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    • v.54 no.5
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    • pp.347-354
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    • 2021
  • In the past few years, various damages have occurred in the vicinity of rivers due to flooding. In order to alleviate such flood damage, structural and non-structural measures are being established, and one of the important non-structural measures is to establish a flood warning system. In general, in order to establish a flood warning system, the water level of the flood alarm reference point is set, the critical flow corresponding thereto is calculated, and the warning precipitation amount corresponding to the critical flow is calculated through the Geomorphological Instantaneous Unit Hydrograph (GIUH) rainfall-runoff model. In particular, when calculating the critical flow, various studies have calculated the critical flow through the Manning formula. To compare the adequacy of this, in this study, the critical flow was calculated through the HEC-RAS model and compared with the value obtained from Manning's equation. As a result of the comparison, it was confirmed that the critical flow calculated by the Manning equation adopted excessive alarm precipitation values and lead a very high flow compared to the existing design precipitation. In contrast, the critical flow of HEC-RAS presented an appropriate alarm precipitation value and was found to be appropriate to the annual average alarm standard. From the results of this study, it seems more appropriate to calculate the critical flow through HEC-RAS, rather than through the existing Manning equation, in a situation where various river projects have been conducted resulting that most of the rivers have been surveyed.

Standardization and Management of Interface Terminology regarding Chief Complaints, Diagnoses and Procedures for Electronic Medical Records: Experiences of a Four-hospital Consortium (전자의무기록 표준화 용어 관리 프로세스 정립)

  • Kang, Jae-Eun;Kim, Kidong;Lee, Young-Ae;Yoo, Sooyoung;Lee, Ho Young;Hong, Kyung Lan;Hwang, Woo Yeon
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.22 no.3
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    • pp.679-687
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    • 2021
  • The purpose of the present study was to document the standardization and management process of interface terminology regarding the chief complaints, diagnoses, and procedures, including surgery in a four-hospital consortium. The process was proposed, discussed, modified, and finalized in 2016 by the Terminology Standardization Committee (TSC), consisting of personnel from four hospitals. A request regarding interface terminology was classified into one of four categories: 1) registration of a new term, 2) revision, 3) deleting an old term and registering a new term, and 4) deletion. A request was processed in the following order: 1) collecting testimonies from related departments and 2) voting by the TSC. At least five out of the seven possible members of the voting pool need to approve of it. Mapping to the reference terminology was performed by three independent medical information managers. All processes were performed online, and the voting and mapping results were collected automatically. This process made the decision-making process clear and fast. In addition, this made users receptive to the decision of the TSC. In the 16 months after the process was adopted, there were 126 new terms registered, 131 revisions, 40 deletions of an old term and the registration of a new term, and 1235 deletions.

The role of Forensic Nurse in the situation of Sexual Assault (성폭력 발생시 법의간호사의 역할)

  • Youk, Gi-Young;Kwak, Jyung-Sik
    • Journal of forensic and investigative science
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    • v.1 no.1
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    • pp.31-44
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    • 2006
  • The importance regarding the notion of immediate medical treatment and nursing for the victims of sexual crimes is not widely recognized yet in Korea. Throughout this research is focused on the nursing systems and the system of foreign countries in reference to sexual crime victims, and the conclusion is as follows. In Korea, there are currently no educational or medical institutes for the medical handling for the victims of sexual crimes, and the role of nurses in the medical institutes is insufficient. In addition, the basis for the standard of operation regarding the initial response, evidence collection, pursuit of systematical evidence and data is not established even in the sexual assault counseling/advocacy center. Therefore, it is necessary to foster the sexual assault nurse examiner for the sexual crime victims, and to develop adequate training programs based on the present situation in Korea. Though the cooperation among government, medical institutes, and social movement groups, it is essential to initiate effective and publicly-trusted specialized training programs for forensic nurses who will be fully charged with the treatment of sexual crime victims. By introducing the sexual assault nurse examiner system, it can be possible to develop advanced treatment for the child or adolescent victims of sex crimes.

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Efficacy of Fine Needle Aspiration Biopsy in Parotid Gland Tumors (이하선 종양에서 세침흡인검사의 유용성)

  • Lee, Chang-Hee;Lee, Hyun-Sub;Jin, Sung-Min;Lee, Sang-Hyuk;Pyo, Jung-Soo;Sohn, Jin-Hee
    • Korean Journal of Head & Neck Oncology
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    • v.27 no.2
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    • pp.204-209
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    • 2011
  • Background and Objectives : The usefulness of fine needle aspiration biopsy(FNAB) for diagnosis of parotid gland tumors is controversial, because of the generalized belief requiring surgery for most parotid tumors. The aim of this study was to evaluate the efficacy of FNAB for diagnosis in parotid gland tumors. Material and Methods : FNAB was performed in 91 patients who underwent parotid surgery at Kangbuk Samsung Hospital from January 2007 to December 2010. The result of FNAB, 11 malignancies and 75 benign tumors and 5 non-neoplasms were analyzed and compared with the final histopathologic diagnoses. Sensitivity, specificity, accuracy, positive predictive value(PPV), and negative predictive value(NPV) were calculated using final histopathologic diagnosis of the surgical specimen as the standard diagnostic reference for comparative analysis. Results : 86 specimens(94.5%) were suitable for evaluation. We compared the result of FNAB and the final histopathology in 79(89.4%) cases. The sensitivity, specificity, accuracy, PPV, and NPV of FNAB for detecting pleomorphic adenoma was 95.8%, 88.4%, 92.3%, 90.2%, and 95.0%. In Warthin's tumor, results were 86.4%, 94.2%, 92.3%, 82.6%, and 95.6%. Among 11 patients who were diagnosed with malignancy on final histopathologic report, only 3(30%) patients were diagnosed with the same as on FNAB, the other 8 patients were initially diagnosed incorrectly as benign tumors in FNAB. There were no complications related to FNAB. Conclusion : Diagnostic accuracy for FNAB in benign parotid tumors was high. However, in malignant tumors, FNAB shows low diagnostic usefulness compared with benign tumors. FNAB can be effective and safe diagnostic technique for evaluating the benign parotid glands tumors.

On-site Water Nitrate Monitoring System based on Automatic Sampling and Direct Measurement with Ion-Selective Electrodes

  • Kim, Dong-Wook;Jung, Dae-Hyun;Cho, Woo-Jae;Sim, Kwang-Cheol;Kim, Hak-Jin
    • Journal of Biosystems Engineering
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    • v.42 no.4
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    • pp.350-357
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    • 2017
  • Purpose: In-situ monitoring of water quality is fundamental to most environmental applications. The high cost and long delays of conventional laboratory methods used to determine water quality, including on-site sampling and chemical analysis, have limited their use in efficiently managing water sources while preventing environmental pollution. The objective of this study was to develop an on-site water monitoring system consisting mainly of an Arduino board and a sensor array of multiple ion selective electrodes (ISEs) to measure the concentration of $NO_3$ ions. Methods: The developed system includes a combination of three ISEs, double-junction reference electrode, solution container, sampling system consisting of three pumps and solenoid valves, signal processing circuit, and an Arduino board for data acquisition and system control. Prior to each sample measurement, a two-point normalization method was applied for a sensitivity adjustment followed by an offset adjustment to minimize the potential drift that could occur during continuous measurement and standardize the response of multiple electrodes. To investigate its utility in on-site nitrate monitoring, the prototype was tested in a facility where drinking water was collected from a water supply source. Results: Differences in the electric potentials of the $NO_3$ ISEs between 10 and $100mg{\cdot}L^{-1}$ $NO_3$ concentration levels were nearly constant with negative sensitivities of 58 to 62 mV during the period of sample measurement, which is representative of a stable electrode response. The $NO_3$ concentrations determined by the ISEs were almost comparable to those obtained with standard instruments within 15% relative errors. Conclusions: The use of the developed on-site nitrate monitoring system based on automatic sampling and two-point normalization was feasible for detecting abrupt changes in nitrate concentration at various water supply sites, showing a maximum difference of $4.2mg{\cdot}L^{-1}$ from an actual concentration of $14mg{\cdot}L^{-1}$.

Establishment of Quality Control System for Angiographic Unit (IVR장치의 성능 평가 기준 개발)

  • Kang, Byung-Sam;Son, Jin-Hyun;Kim, Seung-Chul
    • The Journal of the Korea Contents Association
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    • v.11 no.1
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    • pp.236-244
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    • 2011
  • Recently, the number of interventional procedures has increased dramatically as an alternative of invasive surgical procedure. The need for the quality control program of the angiographic units has also increased, because of concerns about the increased patient dose and the importance of image quality of angiographic units for the successful procedures. The purpose of this study was to propose an optimal guideline for the quality control program of the angiographic units. We reviewed domestic and international standards about medical imaging system and we evaluated the quality of 61 angiographic units in Korea with the use of NEMA 21 phantom. According to the results of our study, we propose a guideline for the quality control program of the angiographic units. Quality control program includes tube voltage test, tube current test, HVL test, image-field geometry test, spatial resolution test, low-contrast iodine detectability test, wire resolution test, phantom entrance dose test. Proposed reference levels are as follows: PAE < $\pm$ 10% in tube voltage test, PAE < $\pm$ 15% in tube current test, minimum 2.3 mmAl at 80 kVp in HVL test, minimum 'acceptable' level at image-field geometry test, 0.8 lp/mm for detector size of 34-40cm, 1.0 lp/mm for detector size of 28-33cm, 1.2 lp/mm for detector size of 22-27cm in spatial resolution test, minimum 200mg/cc in low contrast iodine detectability test, phantom entrance dose should be under 10R/min, 0.012 inch wire should be seen at static wire resolution test, and 0.022 inch wire should be seen at moving wire resolution test.

An Efficient Weight Signaling Method for BCW in VVC (VVC의 화면간 가중 양예측(BCW)을 위한 효율적인 가중치 시그널링 기법)

  • Park, Dohyeon;Yoon, Yong-Uk;Lee, Jinho;Kang, Jungwon;Kim, Jae-Gon
    • Journal of Broadcast Engineering
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    • v.25 no.3
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    • pp.346-352
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    • 2020
  • Versatile Video Coding (VVC), a next-generation video coding standard that is in the final stage of standardization, has adopted various techniques to achieve more than twice the compression performance of HEVC (High-Efficiency Video Coding). VVC adopted Bi-prediction with CU-level Weight (BCW), which generates the final prediction signal with the weighted combination of bi-predictions with various weights, to enhance the performance of the bi-predictive inter prediction. The syntax element of the BCW index is adaptively coded according to the value of NoBackwardPredFlag which indicates if there is no future picture in the display order among the reference pictures. Such syntax structure for signaling the BCW index could violate the flexibility of video codec and cause the dependency issue at the stage of bitstream parsing. To address these issues, this paper proposes an efficient BCW weight signaling method which enables all weights and parsing without any condition check. The performance of the proposed method was evaluated with various weight searching methods in the encoder. The experimental results show that the proposed method gives negligible BD-rate losses and minor gains for 3 weights searching and 5 weights searching, respectively, while resolving the issues.