• Asian Pacific Journal of Cancer Prevention
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• v.14 no.5
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• pp.2937-2943
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• 2013

Backgrounds: Polymorphisms of OPRM1 A118G and ABCB1 C3435T have been suggested to contribute to inter-individual variability regarding pain sensitivity, opioid usage, tolerance and dependence and incidence of adverse effects in patients with chronic pain. This study aimed to investigate the association of both two polymorphisms with opioid requirements in Chinese patients with cancer pain. Methods: The genotypes of rs1799971 (OPRM1) and rs1045642 (ABCB1) were determined by PCR-RFLP and direct sequencing methods respectively in 112 patients with cancer-related pain. Comparisons between the different genotype or allele groups were performed with t-tests or one-way ANOVA tests, as appropriate. The potential relationship of allele number with opioid response was performed with a trend Jonckheere-Terpstra test. Results: In the 112 subjects, the frequencies of variant 118 G and 3435T allele were 38.4% and 37.9%, respectively. Significant higher 24h-opioid doses were observed in patients with GG (P=0.0004) and AG + GG (P=0.005) genotypes than the AA carriers. The dominant mutant 118G allele tended to be associated with progressively increasing 24h-opioiddoses (P=0.001). Compared with CC/CT, patients with ABCB1 TT genotype received higher 24h- and weight-surface area-adjusted-24h- opioids doses (P=0.057 and 0.028, respectively). Conclusions: The OPRM1 A118G single nucleotide polymorphism (SNP) is a key contributor for the inter-individual variability in opioidrequirements in Chinese cancer pain patients. This may possibly extend to the ABCB1 C3435T SNP.

• Journal of Families and Better Life
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• v.30 no.5
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• pp.121-134
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• 2012

The purpose of this study was to investigate the influences of adolescents' body image and communication with their parents on the alienation of male and female middle school students. The subjects were 253 middle school students. The data were analyzed with SPSS win 18.0 using Cronbach's ${\alpha}$, t-test, one-way ANOVA, Scheff$\acute{e}$ test and stepwise regression. The findings showed that problematic communication with the father was the strongest factor in explaining the alienation of male middle school students. The second strongest factor was the middles school student's open communication with the mother, and the third strongest factor was the middle school student's perception of physical health. Unlike male students, open communication with the father was the strongest factor in explaining the alienation of female middle school students. Problematic communication with the mother was the second strongest factor. Perception of physical appearance was the third strongest, and perception of physical health was the fourth strongest factor. Based on the results of the study, implications were discussed in terms of the alienation of male and female middle school students.

• Journal of the Korean Institute of Telematics and Electronics S
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• v.35S no.7
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• pp.72-85
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• 1998

In this paper, we propose a new method that sequentially estimates TDOA(Time Delay Of Arrival) and FDOA(Frequency Delay Of Arrival) for extracting the information about the bearing and relative velocity of a target in passive radar or sonar arrays. The objective is to efficiently estimate the TDOA and FDOA between two sensor signal measurements, corrupted by correlated Gaussian noise sources in an unknown way. The proposed method utilizes the one dimensional slice function of the third order cumulants between the two sensor measurements, by which the effect of correlated Gaussian measurement noises can be significantly suppressed for the estimation of TDOA. Because the proposed sequential algoritjhm uses the one dimensional complex ambiguity function based on the TDOA estimate from the first step, the amount of computations needed for accurate estimationof FDOA can be dramatically reduced, especially for the cases where high frequency resolution is required. It is demonstrated that the proposed algorithm outperforms existing TDOA/FDOA estimation algorithms based on the ML(maximum likelihood) criterionandthe complex ambiguity function of the third order cumulant as well, in the MSE(mean squared error) sense and computational burden. Various numerical resutls on the detection probability, MSE and the floatingpoint computational burden are presented via Monte-Carlo simulations for different types of noises, different lengths of data, and different signal-to-noise ratios.

• Korean journal of food and cookery science
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• v.19 no.5
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• pp.581-590
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• 2003

The purpose of this study was to identify the combinations of factors combinations conferring the highest utility of family restaurants to university students, and establish the relative importance of these factors in terms of their contribution to total utility. 196 of 200 questionnaires were utilized for the analysis. (Eds note: to whom were the questionnaires administered) Frequencies, crosstabs, and the conjoint, max. utility, BTL and Logit models, K-means cluster and one-way ANOVA analysesis, and the Friedman test were the statistical methods used for this study. The findings from this study were as follows: 1) the Pearson's R and Kendall's tau statistics (Eds note: these were not mentioned earlier) show that the model (Eds note: which model is this) fits the data well. 2) it was found that of all the respondents, especially the first and third clusters, regarded both the type of food and the price as very important factors. 3) it was found that all the respondents, especially the third cluster, most preferred a family restaurant (design and simulation) that provided less than 6 fusion and traditional foods. The first cluster most preferred family restaurant (design) that provided over 10 traditional and less than 6 ethnic foods. The second cluster most preferred a family restaurant (design and simulation) that provided over 10 traditional foods. 4) the results of the study have provided some insights into the effective types of family restaurant designs that can be successfully developed by those who manage menu variety, quality and type of food, price, and quality of service to university students dining at family restaurants.

• 대한예방의학회:학술대회논문집
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• 1994.02b
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• pp.84-86
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• 1994

AS A SOCIETY, we are in conflict with ourselves about the cost of health care. 1 On one hand, we want the best care possible, regardless of cost. On the other hand, we are not willing to pay the cost of the care we want. Our conflict parallels a flaw in the medical marketplace. An essential condition for achieving an equilibrium between cost and value is that the two must be connected through decisions. When people decide what products and services (goods) they want, they must not only see the value they will receive, but they mast also be responsible for the costs. Because of a variety of features of the medical marketplace-most notably third-party coverage, third-party advice, and uncertainty about outcomes-the required connection between value and cost is severed. The result is what we see. One side of our collective mind demands more services while the other side cries that costs are too high. Resolving our conflict will require connecting value to cost. An essential step in accomplishing this will be to incorporate costs in practice policies. 1 As controversial as that thought might seem (the great majority of practice policies currently do not take costs into account except in the most rudimentary way), arriving at the conclusion is the easy part. A more difficult issue is how to implement the goal of connecting value to cost. Suppose we agree that, in principle, costs should be considered when practice policies are designed, and that an activity should be recommended and covered only if its health outcomes (benefits minus hanns) are deemed to be worth its costs. The next questions are, Who should do the deeming? What should the deemers be asked?

• The Korean Journal of Food & Health Convergence
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• v.6 no.4
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• pp.1-6
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• 2020

Food hygiene and nutrition is a serious public health concern. It is the responsibility of providers and duty of consumers to ensure that hygienic and nutritious food is being served and consumed respectively. A cross-sectional study was conducted among 384 students to assess the perception of hygiene and nutrition of food in the restaurant of Pokhara Valley, Nepal. Data were collected by a self-administered questionnaire. Two-third of the respondents were female in this study. The taste was the most common reason for the consumption of food in the restaurant. In the same way, more than two-thirds of the respondents considered restaurants' food for not having a balanced diet. Around one-third of the respondents consumed food high in vitamins and minerals, protein, carbohydrate, and calories in restaurants. Around two-thirds of the respondents considered hygiene of food in restaurants as slightly hygienic. More than two-thirds of the respondents considered unhealthy to eat food in the restaurant. The study found the association between education status, family type with a taste of the food. Proper awareness, promotion activities for the healthy nutrition lifestyle & food safety education is highly recommended at the local level.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2021.05a
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• pp.157-158
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• 2021

Big data in the supply chain mainly comes from four aspects. One is the relevant data inevitably generated in the process of product value transfer of enterprises in the supply chain, such as production equipment quality data, planned procurement data, product data, etc; On the other hand, it is derived from the ERP data of various companies in the supply chain; The third is e-commerce data from the customer, and the last is data from external or manually entered data. A third-party data service center analysis and mining the data to predict and control the inventory in the process of supply chain operation. It brings innovation and change of management technology and way of thinking to the whole supply chain in many aspects, and finally achieves the goal of coordinated inventory and zero inventory of the whole supply chain.

• Korean Journal of Health Education and Promotion
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• v.27 no.4
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• pp.123-129
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• 2010

Objectives: The aim of this study is to seek an effective way to support smoking cessation by analyzing any change to the pattern of nicotine dependence according to the change in time. Methods: The study was conducted with 800 male smokers who had participated in smoking cessation programs at public health centers from July 16, 2005 to July 15, 2008. Latent growth curve modeling approach was used for data analysis. Results: From the developmental trajectory of individual nicotine dependence, while nicotine dependence of smokers with high nicotine dependence in the first year was slightly decreased in the third year, smokers with low nicotine dependence in the year showed dramatically lower nicotine dependence in the third year. Compared with those who did not successfully quit smoking, the initial value of nicotine dependence of those who successfully quit smoking in the first and the second year was low. Over the years, nicotine dependence was decreased. Conclusion: From this study it was demonstrated that nicotine dependence was reduced through the practice of smoking cessation and reduced nicotine dependence was a factor which affects successful smoking cessation. These results indicate that multiple attempts to quit smoking finally reduces nicotine dependence. Reduced nicotine dependence is likely to increase the possibility of successful smoking cessation.

• The Journal of Korean Academic Society of Nursing Education
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• v.23 no.2
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• pp.205-213
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• 2017

Purpose: This study observes the degrees of perfectionism (both self-oriented and socially-prescribed perfectionism), academic resilience, and satisfaction with major in nursing students and identifies the influence of perfectionism and academic resilience on satisfaction with major. Methods: Data from 115 second or third-year students in a nursing were collected for two months at different three universities. The data were analyzed with descriptive statistics, independent t-test, one-way ANOVA, Pearson correlation coefficient, and hierarchical multiple regression. Results: Satisfaction with major was higher for second year students compared to third year students. And the satisfaction was higher for those with a higher Grade point average (${\geq}_-3.5$) compared to those with a lower. Self-oriented perfectionism had a higher score than socially-prescribed perfectionism and academic resilience based on self-control was rated the highest score of the subcategories. The degree of satisfaction was positively correlated with Self-oriented perfectionism and academic resilience. The final regression model showed that grade and academic resilience accounted for 34.2% of the variance in predicting the level of satisfaction with major. Conclusion: The results suggest that it is crucial to find a strategy that could enhance academic resilience, especially designed for upper-year university students, to improve the level of satisfaction with major.

• Korean Journal of Human Ecology
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• v.4 no.1
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• pp.31-38
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• 1995

The purpose of this study was to examine the relationship between social networks and perceived self-competence. The subject were 350 third and sixth graders selected from a public elementary school in Seoul. The children were administered the Pattison Psychosocial Network Inventory and The Self Perception Profile for Children. Three major questions are addressed; l)age changes 2)sex differences, and 3) the relation between the characteristics of social networks and self-perceived competence. Data were analyzed by pearson's product moment correlation, one-way ANOVA. Proportion measures were also used since they had allowed for the observation of relationship between two subsets of people within given categories(e.g.,the number of relatives divided by the number of relatives plus nonrelatives). The effects of age and sex of child on the number and daily contact with kin, nankin, peers, adults, males, and females were found. Sixth graders had a larger number of adults than third graders. While children had a greater number of adults than peers, they had more contact with peers than with adults in their network. It was found that boys had greater number of people in their network than girls. And boys had a larger number of and more contact with males, and girls had a larger number of more contact with females. The structure of childrens' social networks structure were correlated with perceived self-competence.