• Progress in Medical Physics
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• v.15 no.2
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• pp.84-93
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• 2004

Stereotactic radiosurgery (SRS) is a technique that delivers a high dose to a target legion and a low dose to a critical organ through only one or a few irradiations. For this purpose, many mathematical methods for optimization have been proposed. There are some limitations to using these methods: the long calculation time and difficulty in finding a unique solution due to different tumor shapes. In this study, many clinical target shapes were examined to find a typical pattern of tumor shapes from which some possible ideal geometrical shapes, such as spheres, cylinders, cones or a combination, are assumed to approximate real tumor shapes. Using the arrangement of multiple isocenters, optimum variables, such as isocenter positions or collimator size, were determined. A database was formed from these results. The optimization procedure consisted of the following steps: Any shape of tumor was first assumed to an ideal model through a geometry comparison algorithm, then optimum variables for ideal geometry chosen from the predetermined database, followed by a final adjustment of the optimum parameters using the real tumor shape. Although the result of applying the database to other patients was not superior to the result of optimization in each case, it can be acceptable as a plan starling point.

• Journal of Astronomy and Space Sciences
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• v.31 no.3
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• pp.225-233
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• 2014

The first Korean satellite laser ranging (SLR) system, Daedeok SLR station (DAEK station) was developed by Korea Astronomy and Space Science Institute (KASI) in 2012, whose main objectives are space geodesy researches. In consequence, Korea became the $25^{th}$ country that operates SLR system supplementing the international laser tracking network. The DAEK station is designed to be capable of 2 kHz laser ranging with precision of a few mm both in daytime and nighttime observation of satellites with laser retro-reflector array (LRA) up to the altitude of 25,000 km. In this study, characteristics and specifications of DAEK station are investigated and its data quality is evaluated and compared with International Laser Ranging Service (ILRS) stations in terms of single-shot ranging precision. The analysis results demonstrated that the DAEK station shows good ranging performance to a few mm precision. Currently, the DAEK station is under normal operations at KASI headquarters, however, it will be moved to Sejong city in 2014 to function as a fundamental station for space geodesy researches in combination with other space geodesy systems (GNSS, VLBI, DORIS, etc.).

• Korean Security Journal
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• no.49
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• pp.97-129
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• 2016

This study is empirically intended to look into the effects of security martial arts leader's leadership behaviors on their role perception and coaching confidence, and the mediating effects of their role perception in the relationship between their leadership behaviors and their coaching confidence. To achieve this, a survey was carried out to incumbent security martial arts leaders. The questionnaires were used for data analysis. The correlation analysis prior to a test of research hypothesis showed that there was a significant positive relationship between all potential factors(< p.01). Especially, there was a high relationship between psychological coaching confidence, human relational coaching confidence, exercise coaching, exercise prescription, and volunteer activities. The detailed results of hypothesis verification were as follows: First, hypothesis 1 showed that leadership behaviors had a significant positive effect on role perception, supporting hypothesis 1. Second, hypothesis 2 showed that role perception had a significant positive effect on coaching confidence, supporting hypothesis 2. Third, hypothesis 3 showed that leadership behaviors had a significant positive effect on coaching confidence, supporting hypothesis 3. Fourth, hypothesis 4 showed that role perception was partially mediated in the effects of leadership behaviors on coaching confidence, supporting hypothesis 4. The findings suggest that the effects of security martial arts leader's leadership behaviors on their coaching confidence can be maximized in combination with their role perception.

• Child Health Nursing Research
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• v.19 no.3
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• pp.216-227
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• 2013

Purpose: Despite the well-known public health benefits of vaccination, increasing public concern about the safety of childhood vaccinations has led some parents to refuse or hesitate having their children immunized. The purpose of this study was to identify the subjectivity of parents toward refusal of childhood vaccination. Methods: Q-methodology, in which subjective viewpoints are explored and analyzed using a combination of quantitative and qualitative techniques, was used. Thirty-five participants were asked to rank 42 statements on diverse issues of childhood vaccination according to a continuous 9-point scale ranging from -4 for strongly disagree to +4 for strongly agree. Collected data was analyzed using the PC-QUANAL program. Results: The results revealed three discrete groups of parents in the refusal of children's immunization: type I, distrust; type II, concern about side effects, and type III, belief that vaccinations are unnecessary. Conclusion: Special nurse counselors who can provide correct information about vaccination based on the three types should be part of the government policy. Customized education programs to shift viewpoints should be also redeveloped according to the results in this study.

• Spatial Information Research
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• v.23 no.4
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• pp.91-101
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• 2015

Due to recent increase of indoor spatial information demands, several international standards have been published for indoor spatial information. OGC has also recently published two standards for indoor space; CityGML and IndoorGM. CityGML aims to provide a standard for 3D city modeling and the level of details (LoD) 4 covers the indoor space. IndoorGML focuses only on indoor space and provides several functions to complement the weakness of CityGML. It is therefore recommended to apply IndoorGML as a combination with CityGML. However since the weakness and strengths between these standards are not yet fully studied and understood, there is no well-defined guideline to apply them in a proper way. It means that we need to carry out a comparative study between them for their proper integration. For this reason, we discuss the pros and cons of these standards from two use-cases. The sites for the use-cases cover Lotte World Mall and Jongno-5 subway station, respectively. We studied these use-cases to compare CityGML and IndoorGML through the data construction of CityGML and IndoorGML for these sites. And based on several application scenarios, we also analyzed the weakness and strengths of each standard from different viewpoints. We expect that these comparative studies will be helpful to make a guideline on the application and integration between CityGML and CityGML.

• Korean Journal of Food Science and Technology
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• v.52 no.1
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• pp.40-45
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• 2020

Over 500 genetically modified organisms (GMOs) have been developed since 1996, of which nearly 44% have glufosinate herbicide-tolerant traits. Identification of specific markers that can be used to identify herbicide-tolerant traits is challenging as the DNA sequences of the gene(s) of a trait are highly variable depending on the origin of the gene(s), plant species, and developers. To develop specific PCR marker(s) for the detection of the glufosinate-tolerance trait, DNA sequences of several pat or bar genes were compared and a diverse combination of PCR primer sets were examined using certified reference materials or transgenic plants. Based on both the qualitative and quantitative PCR tests, a primer set specific for pat and non-specific for bar was developed. Additionally, a set of markers that can detect both pat and bar was developed, and the quantitative PCR data indicated that the primer pairs were sensitive enough to detect 0.1% of the mixed seed content rate.

• Analytical Science and Technology
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• v.16 no.5
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• pp.349-357
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• 2003

The universality of low molecular weight metabolites (i.e. amino acids, steroid hormones) allows rapid and straightforward investigation of biochemistry of genetically un-characterized species. Thus in vivo metabolic profiling of amino acid in combination with multivariate data analysis (metabolomics) offers great potential in comparative biology. In this paper, amino acid profiles in biological fluid (media) were studied by using HPLC/FLD. HPLC procedure for amino acids require the formation of derivatives due to the low absorption of the free compounds. o-Phthalaldehyde (OPA) used in association with a thiol, such as 3-mercaptopropionic acid (3-MPA), is one of the most popular and sensitive reagents, which yield quickly fluorescent iso-indoles at room temperature. To improve unstability of OPA/3-MPA derivatization, we optimized injector programs for fixed injection times. Linear regressions for the standard curves were linear in the range 0.5 - 100.0 ppb, giving correlation coefficents above 0.99. The detection limit were 1.70 pmol(GLU) - 23.81 pmol(SER). It is practically useful when the amount of sample is very low on single cells.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.28 no.11
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• pp.837-842
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• 2017

In this paper, as a basic study for combination of turbo equalizer and 4D-8PSK-TCM(4 Dimensional 8 Phase Shift Keying Trellis Coded Modulation) system, which is recommended for X-band band satellite communication in CCSDS, a system combining 8PSK-TCM system and turbo equalizer has designed and performance evaluation of the system has performed. BER performance of 8PSK and 8PSK-TCM systems has evaluated and analyzed in AWGN, Proakis B and Proakis C channels in detail. As results of simulation, BER performance of 8PSK-TCM system is better than 8PSK system in AWGN environment. Furthermore, it can be confirmed that the system combining the 8PSK-TCM system with the turbo equalizer can further improve the BER performance through iterative equalization in the ISI channel environment. The 8PSK-TCM system combined with the turbo equalizer requires SNR of 5.9 dB for BER performance of $10^{-3}$ with 5 iterative equalization in Proakis B and SNR of 9.1 dB for BER of $10^{-2}$ with 5 iterative equalization in Proakis C.

• KIPS Transactions on Software and Data Engineering
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• v.12 no.9
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• pp.381-386
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• 2023

Many existing test case generation researchers extract test cases from models. However, research on generating test cases from natural language requirements is required in practice. For this purpose, the combination of natural language analysis and requirements engineering is very necessary. However, Requirements analysis written in Korean is difficult due to the diverse meaning of sentence expressions. We research test case generation through natural language requirement definition analysis, C3Tree model, cause-effect graph, and decision table steps as one of the test case generation methods from Korean natural requirements. As an intermediate step, this paper generates test cases from C3Tree model-based decision tables using meta-modeling. This method has the advantage of being able to easily maintain the model-to-model and model-to-text transformation processes by modifying only the transformation rules. If an existing model is modified or a new model is added, only the model transformation rules can be maintained without changing the program algorithm. As a result of the evaluation, all combinations for the decision table were automatically generated as test cases.

• Journal of Life Science
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• v.33 no.12
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• pp.1025-1035
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• 2023

In this study, we analyzed SNPs that appear between Korean and Chinese Scapharca subcrenata using the nucleotide sequence data of S. subcrenata analyzed by genotyping by sequencing (GBS). To distinguish the country of origin for S. subcrenata in Korean and Chinese, we developed a primer set as single nucleotide polymorphism (SNP) markers for quantitative real-time PCR (qPCR) analysis and validated by sequencing SNPs. A total of 180 samples of S. subcrenata were analyzed by genotyping by sequencing, and 15 candidate SNPs were selected. SNP marker selection for country of origin were identified through real-time qPCR. Insertion 1 and SNP 21 markers showed the most distinct separation between the sequence types as well as the country of origin through qPCR, with the observed amplification patterns matching the expected outcomes.. Additionally, in a blind test conducted by mixing samples of S. subcrenata at random, Insertion 1 showed 74% accuracy, 52% sensitivity, and 96% specificity, and SNP 21 showed 86% accuracy, 79% sensitivity, and 93% specificity. Therefore, the two SNP markers developed are expected to be useful in verifying the authenticity of the country of origin of S. subcrenata when used independently or in combination.