• 한국지역지리학회지
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• 제21권3호
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• pp.489-502
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• 2015

실리콘펜 또는 케임브리지 현상으로도 알려져 있는 케임브리지 클러스터는 생명공학 산업 및 정보통신 산업에 특화되어 있는 혁신 클러스터로 잘 알려져 있다. 본 연구는 케임브리지 클러스터의 진화구조를 트리플힐릭스 관점을 중심으로 고찰한 것이다. 케임브리지 클러스터는 케임브리지대학을 중심축으로 형성된 자연발생적 클러스터로 간주할 수 있으나, 오늘날 케임브리지가 세계적인 첨단산업 클러스터의 기반을 갖추게 된 밑바탕에는 1960년대 후반에 결성된 산-학-관 협력체인 '케임브리지지역발전위원회'의 활동과 그 결과로 만들어진 모트보고서가 중요한 영향을 미쳤다. 그 후 1970년대부터 본격화된 클러스터의 성장과정에는 케임브리지대학의 칼리지들이 조성하기 시작한 사이언스 파크와 케임브리지대학의 스핀오프(스핀아웃) 활동이 활발하게 나타났다. 클러스터 진화의 역동성을 주도하는 지역 내 스핀오프 활성화의 기저에는 케임브리지 지역에 오랜 세월 누적되어 온 기업가주의 문화와 창업 및 기업 활동을 촉진하는 기업가 네트워크와 사회자본의 영향이 중요하게 작용했다. 그러나 2000년대 들어 대학의 재정 지원을 축소하고 기업가적 대학으로의 전환을 유도하는 정부의 정책기조가 심화됨에 따라 케임브리지대학의 스핀오프 활동은 크게 위축되었고, 이것이 케임브리지 클러스터의 역동적 진화를 위협하는 요소로 작용하고 있다.

• 한국경제지리학회지
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• 제26권4호
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• pp.375-390
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• 2023

본 연구는 국외 바이오산업 클러스터의 태동 과정과 경쟁력 결정요인을 살펴보았다. 바이오산업은 다양한 산업에 접목할 수 있으며, 인공지능과 정보통신기술 등과 결합한 고부가가치 창출이 가능한 까닭에 세계 주요국에서 주목하는 유망 신산업이다. 또한, 기업, 대학, 병원, 연구기관, 정부 등 여러 이해관계자와 연계·협력이 필요하다는 점에서 클러스터의 중요성이 강조된다. 그러나 이 같은 중요성과 관심에 비해 국내의 관련 연구는 다소 미흡한 편이다. 특히, 국외 사례 연구도 소수의 선도 클러스터에 지나치게 치우쳐 있어, 국내 지역 실정에 부합하지 않는 정책과 발전 방안을 내놓는 경향이 있다. 이 같은 문제를 완화하고자, 본 연구는 미국의 바이오 헬스 캐피털 리전, 영국의 케임브리지 클러스터, 덴마크와 스웨덴의 메디콘밸리 세 곳의 태동 및 성장 과정을 살펴보았다. 이를 통해, 부족했던 관련 사례 연구를 풍부하게 하고, 각 클러스터의 경쟁력 결정요인을 파악하여 국내 바이오산업 클러스터의 조성과 육성에 대한 시사점을 제시하고자 한다.

• International Journal of Computer Science & Network Security
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• 제22권4호
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• pp.17-26
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• 2022

Sensor Nodes play a major role to monitor and sense the variations in physical space in various real-time application scenarios. These nodes are powered by limited battery resources and replacing those resource is highly tedious task along with this it increases implementation cost. Thus, maintaining a good network lifespan is amongst the utmost important challenge in this field of WSN. Currently, energy efficient routing techniques are considered as promising solution to prolong the network lifespan where multi-hop communications are performed by identifying the most energy efficient path. However, the existing scheme suffer from performance related issues. To solve the issues of existing techniques, a novel hybrid technique by merging particle swarm optimization and game theory model is presented. The PSO helps to obtain the efficient number of cluster and Cluster Head selection whereas game theory aids in finding the best optimized path from source to destination by utilizing a path selection probability approach. This probability is obtained by using conditional probability to compute payoff for agents. When compared to current strategies, the experimental study demonstrates that the proposed GTPSO strategy outperforms them.

• World Technopolis Review
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• 제4권2호
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• pp.87-103
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• 2015

This paper aims to explore how firms develop and grow in regional clusters based in a developing country. The argument is that start-ups / small and large firms are able to grow by developing linkages or networks for resources within clusters - and this tenet is based on studies of firms that are based from such clusters as Silicon Valley in the US, Cambridge in UK and other clusters from which have evolved over long periods of time. Most of the time we hear narratives from the developed world where there are brownfield cluster development efforts. In developing countries governments are making efforts to develop clusters from scratch - which in this paper we term as greenfield cluster versus a brownfield development, which is where the cluster is developed based on existing and new organisations in a region. In this paper, we believe the context of clusters can be important in determining the way firms develop linkages for their growth - and we look at two contexts in Malaysia ie. A greenfield cluster and a brownfield cluster. The paper presents findings from case studies of firms in a greenfield cluster (Cyberjaya) and a brown field cluster (Penang) in Malaysia. The cases reveal fairly different approaches to development of linkages or networks, which we hope will provides insights to cluster development officials and policy makers and implications to researchers for developing studies of clusters and innovation systems.

• Bulletin of the Korean Chemical Society
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• 제31권4호
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• pp.934-940
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• 2010

The reduction of [$Os_3(CO)_{11}P(OMe)_3$] and subsequent ionic coupling of the reduced species with $[Ru({\eta}^5-C_5H_5)(CH_3CN)_3]^+$ resulted in the formation of [$Os_3(CO)_{11}P(OMe)_3(Ru({\eta}^5-C_5H_5))_2$] which can be converted to spiked tetrahedral cluster, [$HOs_3(CO)_{11}P(OMe)_3Ru_2({\eta}^5-C_5H_5)(C_5H_4)$] via the intramolecular hydrogen transfer. Due to the unavailability of a suitable single crystal, the PW91/SDD and LDA/SDD density functional methods were used to predict possible structures and the available spectroscopic information (IR, NMR) of [$Os_3(CO)_{11}P(OMe)_3(Ru({\eta}^5-C_5H_5))_2$]. The most probable geometry found by constrained search is the isomer (a2) in which the phosphite, $P(OMe)_3$, occupies an axial position on one of the two osmium atoms that is edge bridged by the $Ru(CO)_2({\eta}^5-C_5H_5)$ unit. By using the most probably geometry, the predicted infrared frequencies and $^1H$, $^{13}C$ and $^{31}P$ NMR chemical shifts of the compound are in the same range as the experimental values. For this type of complex, the LDA/SDD method is appropriate for IR predictions whereas the OPBE/IGLO-II method is appropriate for NMR predictions. The activation energy and reaction energy of the intramolecular hydrogen transfer coupled with the structural change of the transition metal framework were estimated at the PW91/SDD level to be 110.32 and -0.14 kcal/mol respectively.

• 천문학회보
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• 제41권2호
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• pp.36.1-36.1
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• 2016

This is a presentation of the paper published as Kimm et al. 2016, ApJ, 823, 52. We investigate the formation of metal-poor globular clusters (GCs) at the center of two dark matter halos with $Mhalo{\sim}4{\times}107Msun$ at z>10 using cosmological radiation-hydrodynamics simulations. We find that very compact (${\leq}1$ pc) and massive (${\sim}6{\times}105Msun$) clusters form rapidly when pristine gas collapses isothermally with the aid of efficient $Ly{\alpha}$ emission during the transition from molecular-cooling halos to atomic-cooling halos. Because the local free-fall time of dense star-forming gas is very short (${\ll}1Myr$), a large fraction of the collapsed gas is turned into stars before stellar feedback processes blow out the gas and shut down star formation. Although the early stage of star formation is limited to a small region of the central star-forming disk, we find that the disk quickly fragments due to metal enrichment from supernovae. Sub-clusters formed in the fragmented clouds eventually merge with the main cluster at the center. The simulated clusters closely resemble the local GCs in mass and size but show a metallicity spread that is much wider than found in the local GCs. We discuss a role of pre-enrichment by Pop III and II stars as a potential solution to the latter issue. Although not without shortcomings, it is encouraging that a naive blind (not tuned) cosmological simulation presents a possible channel for the formation of at least some massive GCs.

• Asian Pacific Journal of Cancer Prevention
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• 제14권4호
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• pp.2429-2432
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• 2013

Background and Objectives: Yanting in Sichuan Province is one of the highest risk areas of esophageal cancer (EC) in the world. We here summarize the epidemiology of EC in Yanting using data from the national screening programme during 2006-2011. Methods: Random cluster sampling was used to select a proportion of natural villages from six towns in Yanting, and residents aged 40-69 years old were invited for screening. Participants were screened using endoscopy with iodine staining and then confirmed by histological examinations. Results: The overall detection rates of low-grade hyperplasia (LH), moderate hyperplasia (MH), high-grade hyperplasia (HH), carcinoma in situ (CIS), intramucosal carcinoma (IC) and invasive carcinoma (INC) were 5.33%, 1.28%, 0.68%, 0.15%, 0.06% and 0.29%, respectively. The detection rates of LH, MH, HH and INC increased with age, reaching the peak among those aged 60-65 years, and the prevalences of LH and MH were higher among men than among women. In addition, the detection rates of hyperplasia were much higher in mountainous than in hilly areas. Conclusions: Among the high risk population, there are a great number of people with early-stage EC or precancerous conditions who do not have presenting symptoms. In particular, the elderly, men, or those living in mountainous areas are the most vulnerable population. It is therefore important to reinforce health education and screening services among such high risk populations.