• 한국정보통신학회논문지
• /
• 제20권2호
• /
• pp.437-444
• /
• 2016

일반적인 부정맥 분류 방법의 경우 심방 박동 수와 관련한 PP간격, P모양의 다양성과 같은 조건을 이용하는데, 잡음으로 인해 정확한 P파의 검출이 어렵기 때문에 잡음의 영향을 비교적 적게 받는 R파를 이용하는 것이 유리하다. 따라서 본 연구에서는 R파 중심의 ECG(electrocardiography) 패턴 분석과 템플릿 문턱치를 도입하여 조기수축 부정맥 분류 방법을 제안한다. 이를 위해 형태 연산을 통한 전 처리 과정과 차감 동작 기법을 통해 R파를 검출하였다. 이후 RR 간격의 평균 가중치와 변화율을 이용하여 먼저 조기수축 파형의 패턴을 분류하고, R파의 진폭에 대한 템플릿 문턱값을 통해 조기심실수축과 조기심방수축을 분류하는 알고리즘을 개발하였다. 제안한 방법의 우수성을 입증하기 위해 조기 심방과 심실수축이 30개 이상 포함된 MIT-BIH 6개의 레코드를 대상으로 한 R파의 평균 검출율은 99.77%의 성능을 나타내었고, 조기심실수축과 심방수축 부정맥은 각각 94.91%와 95.76%의 평균 분류율을 나타내었다.

• 한국결정성장학회지
• /
• 제20권4호
• /
• pp.164-167
• /
• 2010

본 연구에서는 HVPE을 이용하여 sapphire(001) 기판 위에 직경 2 inch, 두께 약 1.5 mm인 bulk GaN를 성장하고, 이를 mechanical polishing을 통해 $10{\times}10,\;15{\times}15$ mm 크기의 free-standing GaN template을 제작하여 그 특성을 평가하였다. 성장된 GaN 단결정의 X-ray diffraction pattern 결과 (002) 및 (004) 면으로부터의 회절에 의한 peak가 나타났으며, (002) 면의 DCXRD(Double crystal X-Ray diffraction) rocking curve peak의 반치폭(FWHM)은 98 arcsec으로 나타났다. 제작한 GaN template는 363 nm 파장에서 sharp한 PL spectrum을 나타내었으며, 불순물 defect에 의한 yellow 영역에서의 broad peak은 관찰되지 않았으며, 제작된 GaN template표면의 etch-pit 밀도는 $5{\times}10^6/cm^2$으로 매우 낮았다. 이러한 분석결과를 통하여 성장된 GaN template는 LED 및 LD 등의 청색 발광소자 및 고온, 고출력 소자용 기판재료로 응용이 가능할 것으로 생각 된다.

• 한국GIS학회:학술대회논문집
• /
• 한국GIS학회 2003년도 추계학술대회논문집
• /
• pp.15-20
• /
• 2003

As an emerging technology in Computer graphics areas, SVG(Scalable Vector Graphic) makes it possible to make use of Vector graphics for servicing maps in basic internet browsing environment. SVG based thematic map Internet GIS system implemented by this research is free of special server side GIS mapping system and client side extra technology. It provides high-quality vector map which can interact with the user, template map which can be used for other purpose, glance the future map based on Webservices technologies. Many good characteristics of SVG in mapping at computer screen and reusability of SVG document provide new era of visualzation of geographic information.

• Korean Journal of Chemical Engineering
• /
• 제35권11호
• /
• pp.2283-2289
• /
• 2018

$TiO_2$ microspheres were successfully synthesised by simple solution phase method by using various amount of titanium butoxide as precursor. The prepared $TiO_2$ were characterized by X-ray diffraction (XRD), UV-vis diffuse reflectance absorption spectra (UV-DRS), X-ray photoelectron spectroscopy (XPS) and scanning electron microscopy (SEM). XRD analysis revealed that the as-synthesized $TiO_2$ microsphere poses an anatase phase. The photocatalytic degradation experiments were carried out with three different dyes, such as methylene blue, brilliant black, reactive red-120 for four hours under UV light irradiation. The results show that $TiO_2$ morphology had great influence on photocatalytic degradation of organic dyes. The experimental results of dye mineralization indicated the concentration was reduced by a high portion of up to 99% within 4 hours. On the basis of various characterization of the photocatalysts, the reactions involved to explain the photocatalytic activity enhancement due to the concentration of titanium butoxide and morphology include a better separation of photogenerated charge carriers and improved oxygen reduction inducing a higher extent of degradation of aromatics.

• Molecules and Cells
• /
• 제26권1호
• /
• pp.5-11
• /
• 2008

Stalled DNA replication forks activate specific DNA repair mechanism called post-replication repair (PRR) pathways that simply bypass DNA damage. The bypassing of DNA damage by PRR prevents prolonged stalling of DNA replication that could result in double strand breaks (DSBs). Proliferating cell nuclear antigen (PCNA) functions to initiate and choose different bypassing pathways of PRR. In yeast, DNA replication forks stalled by DNA damage induces monoubiquitination of PCNA at K164, which is catalyzed by Rad6/Rad18 complex. PCNA monoubiquitination triggers the replacement of replicative polymerase with special translesion synthesis (TLS) polymerases that are able to replicate past DNA lesions. The PCNA interaction motif and/or the ubiquitin binding motif in most TLS polymerases seem to be important for the regulation of TLS. The TLS pathway is usually error-prone because TLS polymerases have low fidelity and no proofreading activity. PCNA can also be further polyubiquitinated by Ubc13/ Mms2/Rad5 complex, which adds an ubiquitin chain onto monoubiquitinated K164 of PCNA. PCNA polyubiquitination directs a different PRR pathway known as error-free damage avoidance, which uses the newly synthesized sister chromatid as a template to bypass DNA damage presumably through template switching mechanism. Mammalian homologues of all of the yeast PRR proteins have been identified, thus PRR is well conserved throughout evolution. Mutations of some PRR genes are associated with a higher risk for cancers in mice and human patients, strongly supporting the importance of PRR as a tumor suppressor pathway.

• 한국디지털건축인테리어학회논문집
• /
• 제11권2호
• /
• pp.13-19
• /
• 2011

Starting in modern times by Le Corbusier, architectures made by concretes are still developing in these times. For several decades, the shape of box architecture has been the most familiar type of buildings. Of course "The concrete is the type of box building" isn't always right, but what we have most seen was the buildings which has been stylized and made by concretes. Through modern times to these days based on international style and functionalism, the type of box building was the most effective and good profit type of architecture which has not disregarded the capitalism. Free-form building are becoming a common place, and many of these are designed and constructed using sophisticated techniques. The main technique being used is Generative Technology of Form for free-form construction. People's interest is growing in this, and it is becoming widely used both abroad and domestically. The purpose of this paper is to investigate the use of Generative Technology of Form which is a digitally adapted design methodology in architecture. The digital design process used for contemporary buildings share many typical features that exist within a standard digital template, but also an increasing amount of mass customization that has to be produced at an additional cost. This paper will summarize these features in terms of free-form architecture, and in terms of the digital design process. In fact, 3D models have to be conceded as main design products considering features of Free Form Design Architecture. However it is practical to design twice over, because all forms of architectural drawings are 2D. From now on, design of Free Form Design Building is not to separate between design process and practical process, but to compound them as unified design system applied the process to communicate information interactively. For this, it should be required to impose unified digital design process and perform researches about effective way to apply in the field of Free-form Design Architecture.

• 한국재료학회지
• /
• 제24권6호
• /
• pp.319-325
• /
• 2014

Cobalt nano-rods were fabricated using a template-free electrochemical-deposition process. The structure of cobalt electro-deposits strongly depends on the electrolyte composition and on the density of the applied current. In particular, as the content of boric acid increased in the electrolyte, deposits of semi-spherical nuclei formed, and then grew into one-dimensional nano-rods. From analysis of the electro-deposits created under the conditions of continuous and pulsed current, it is suggested that the distribution of the active species around the electrode/electrolyte interface, and their transport, might be an important factor affecting the shape of the deposits. When transport of the active species was suppressed by lowering the deposition temperature, more of the well-defined nano-rod structures were obtained. The optimal conditions for the preparation of well-defined nano-rods were determined by observing the morphologies resulting from different deposition conditions. The maximum height of the cobalt nano-rods created in this work was $1{\mu}m$ and it had a diameter of 200 nm. Structural analysis proved that the nano-rods have preferred orientations of (111).

• Membrane and Water Treatment
• /
• 제10권5호
• /
• pp.353-360
• /
• 2019

ZSM-5 membrane was prepared on tubular macroporous ${\alpha}$-alumina support using a different synthesis route. The effects of organic template agent and Si/Al ratio of the synthesis gel on morphology, structure, and separation performance of the ZSM-5 membrane used for dehydration of isopropanol were investigated. High water perm-selectivity ZSM-5 membrane with a thickness of about $3.0{\mu}m$ and a low Si/Al ratio of 10.1 was successfully prepared from organotemplate-free synthesis gel with a molar composition of $SiO_2$ : $0.050Al_2O_3$ : $0.21Na_2O$ : NaF : $51.6H_2O$ at $175^{\circ}C$ for 24 h. The ZSM-5 membrane exhibited high pervaporation performance with a flux of $3.92kg/(m^2{\cdot}h)$ and corresponding separation factor of higher than 10,000 for dehydration of 90 wt.% isopropanol/water mixture at $75^{\circ}C$.

• 멤브레인
• /
• 제26권5호
• /
• pp.381-390
• /
• 2016

본 연구에서는 고순도의 모데나이트(Mordenite) 입자를 합성하기 위하여 천연 제올라이트를 시드로 사용하여 시드의 농도 및 수열합성 시간에 따른 천연 제올라이트 시드가 합성에 미치는 영향을 고찰하였다. 그 결과 시드가 입자의 형성에 큰 영향을 끼치는 것을 확인할 수 있었고 시드를 3 g/100 g batch 주입하여 $140^{\circ}C$에서 72시간 동안 수열합성을 진행하였을 때 $1-2{\mu}m$ 사이즈의 고순도 모데나이트 입자를 합성할 수 있었다. 이를 통해 모데나이트 입자의 성장 기구를 규명할 수 있었으며, 모데나이트 입자 형성에 있어 시드는 첫째, 구형 모데나이트 전구체 형성 자리 공급의 역할과, 둘째 모데나이트 원료 물질 소스 역할을 한다는 것을 알 수 있었다. 합성된 모데나이트 입자의 가스 흡착량 분석 결과 $CO_2$ 기체의 흡착량이 97.19 mg/g로 다른 가스들에 비해 비교적 높은 흡착성능을 보였으며, $CO_2/H_2$의 선택도가 가장 우수한 것으로 나타났다. 따라서 이러한 결과들을 바탕으로 용도에 맞는 고순도 상의 모데나이트 입자를 합성할 수 있음을 확인하였고 보다 낮은 가격으로 우수한 분리성능을 갖는 분리막 소재개발에 활용할 수 있을 것이라 판단된다.

• Biotechnology and Bioprocess Engineering:BBE
• /
• 제11권3호
• /
• pp.235-239
• /
• 2006

Due to recent advances in genome sequencing, there has been a dramatic increase in the quantity of genetic information, which has lead to an even greater demand for a faster, more parallel expression system. Therefore, interest in cell-free protein synthesis, as an alternative method for high-throughput gene expression, has been revived. In contrast to in vivo gene expression methods, cell-free protein synthesis provides a completely open system for direct access to the reaction conditions. We have developed an efficient cell-free protein synthesis system by optimizing the energy source and S30 extract. Under the optimized conditions, approximately $650{\mu}g/mL$ of protein was produced after 2h of incubation, with the developed system further modified for the efficient expression of PCR-amplified DNA. When the concentrations of DNA, magnesium, and amino acids were optimized for the production of PCR-based cell-free protein synthesis, the protein yield was comparable to that from the plasmid template.