• Asia pacific journal of information systems
• /
• 제17권4호
• /
• pp.97-112
• /
• 2007

Most traditional newspaper publishers provide online editions to counter the competition of online news providers. However, the relationship between the online and print editions of the same newspaper has not been clearly defined. Some see the online newspaper as a substitute, while others consider it a complement. A 2002 NAA online newspaper consumer survey indicated that one-third of its respondents said they were now using the print newspaper less. Others have argued that the online edition will not wipe out print consumption, and may even complement it. While the print edition offers particular advantages such as portability, less eye strain, and the tactile experience of a printed page, the online edition also offers specific advantages such as access to breaking news, continually updated information, access to old archives, etc. All these factors would tend to lower the degree of interchangeability between the products. However, recent empirical studies show that the online edition is a substitute for rather than a complement of the print edition. Still, to some print readers, the online edition provides additional value. In this paper, by capturing the two different aspects of online editions the substitute aspect and the additional value added aspect as well as other available online alternatives, we develop an analytical model to derive the optimal production and distribution strategies of both online and print editions. Confronting the "free versus fee" issue, we show that it is optimal to provide an online version of the print newspaper for free to non-print subscribers. However, the amount of free news content that the publishers need to put on the Web depends on the available alternatives on the online market. The "fee" and "free" options both have merits and demerits as well. If the publisher charges for the online version of the print newspaper, she can generate revenue from the fee charged to online readers. However, doing so will limit the size of the online audience and further reduce online advertising revenue. At the same time, by providing a high-quality online version and charging for it, the price of the print newspaper must stay low in order to lure high valued readers. On the contrary, if the publisher provides an online version of the print newspaper for free, she can obtain a larger audience for the online version. At the same time, by providing a low-quality online newspaper, the publisher can increase the print newspaper price to get more revenue from high valued offline readers, although no revenue is incoming from online version readers. Through systematic measuring of all the pros and cons, our analysis shows that the optimal option is not "fee" but "free."

• Journal of Korean Neurosurgical Society
• /
• 제29권2호
• /
• pp.222-230
• /
• 2000

Purpose : Resection of the epileptogenic zone in the parietal and occipital lobes may be relevant although only few studies have been reported. Methods : Eight patients with parietal epilepsy and nine patients with occipital epilepsy were included for this study. Preoperatively, all had video-EEG monitoring with extracranial electrodes, MRI, 3D-surface rendering of MRI using Allegro(ISG Technologies Inc., Toronto, Canada), and PET scans. Sixteen patients underwent invasive recording with subdural grid. Eight had parietal resection including the sensory cortex in two. Seven had partial occipital resection. Two underwent total unilateral occipital lobectomy. The extent of the resection was made based mainly on the data of invasive EEG recordings, MRI, and 3D-surface rendering of MRI, not on the intraoperative electrocorticographic findings as usually done. During resection, electrocortical stimulation was performed on the motor cortex and speech area. Results : Out of eight patients with parietal epilepsy, three had sensory aura, two had gustatory aura, and two had visual aura. Six of nine patients with occipital epilepsy had visual auras. All had complex partial seizures with lateralizing signs in 15 patients. Four had quadrantopsia. One had mild right hemiparesis. Abnormality in MRI was noticed in six out of eight parietal epilepsy and in eight out of nine occipital epilepsy. 3D-surface rendering of MRI visualized volumetric abnormality with geometric spatial relationships adjacent to the normal brain, in all of parietal and occipital epilepsy. Surface EEG recording was not reliable in localizing the epileptogenic zone in any patient. The subdural grid electrodes can be implanted on the core of the structural abnormality in 3D-reconstructed brain. Ictal onset zone was localized accurately by subdural grid EEGs in 16 patients. Motor cortex in nine and sensory speech area in two were identified by electrocortical stimulation. Histopathologic findings revealed cortical dysplasia in 10 patients ; tuberous sclerosis was combined in two, hamartoma and ganglioglioma in one each, and subpial gliosis in six. Eleven patients were seizure free at follow-up of 6 months to 37 months(mean 19.7 months) after surgery. Seizures recurred in two and were unchanged in one. Six produced transient sensory loss and one developed hemiparesis and tactile agnosia. One revealed transient apraxia. Two patients with preoperative quadrantopsia developed homonymous hemianopsia. Conclusion : This study suggests that surgical treatment was relevant in parietal and occipital epilepsies with good surgical outcome, without significant neurologic sequelae. Neuroimaging studies including conventional MRI, 3Dsurface rendering of MRI were necessary in identifying the epileptogenic zone. In particular, 3D-surface rendering of MRI was very helpful in presuming the epileptogenic zone in patients with unidentifiable lesion in the conventional MRI, in planning surgical approach to lesions, and also in making a decision of the extent of the epileptogenic zone in patients with identifiable lesion in conventional MRI. Invasive EEG recording with the subdural grid electrodes helped to confirm a core of the epileptogenic zone which was revealed in 3D-surface rendered brain.

• 한국산학기술학회논문지
• /
• 제16권1호
• /
• pp.445-452
• /
• 2015

경두개직류전류자극(tDCS)은 낮은 직류 전류 강도를 사용하여 대뇌피질의 자발적인 신경학적 활동의 흥분성을 증가 또는 감소시키는 신경조절 기법이다. 본 연구의 목적은 tDCS를 적용한 후 다양한 감각 기능의 변화를 측정하는데 있다. tDCS의 효과를 측정하기 위해 CPT 검사를 50명의 건강한 대상자에게 단일 기간(8월4일에서 8월29일), 단일 공간, 단일 맹검법으로 무작위 배정하였다. 신경전도검사는 우세 손의 말초신경 병변을 구별하기 위해 정중 감각과 운동신경을 측정하였다. 대상자들은 각 25명 씩 대뇌피질의 DLPFC의 tDCS 자극군과 대뇌피질의 DLPFC의 tDCS 위자극군으로 2개의 다른 조건 아래서 1 mA의 전류강도로 15분씩 양극 tDCS로 적용하였다. 촉각, 빠른 통증과 느린 통증을 각각 평가하기 위해 우세한 제 2수지에 2000, 250, 그리고 5 Hz의 주파수로 CPT 검사인 Neurometer$^{(R)}$를 이용하여 수치들을 기록하였다. DLPFC의 양극 tDCS 자극군의 CPT 수치들에서는 250과 5 Hz에서 통계적으로 유의한 증가를 보였다. 양극 tDCS 위자극군의 모든 CPT 수치들은 감소하였다. 이러한 결과는 DLPFC의 양극 tDCS가 건강한 대상자들의 감각 지각과 통증 역치들을 조절할 수 있다는 것을 보여준다. 따라서 본 연구는 재활과 통증 치료 분야에서 유용한 치료 방법 중 하나로 제시할 수 있을 것으로 생각한다.

• The Korean Journal of Pain
• /
• 제21권3호
• /
• pp.179-186
• /
• 2008

Background: The adrenergic nervous system in the spinal cord contributes to the development of neuropathic pain after nerve injury. Brain derived neurotrophic factor may facilitate the sympathetic change in the spinal cord and influence the state of neuropathic pain. We probed the effect of chronic repetitive administration of systemic 4-methylcatechol, which is known to be a neurotrophic factor inducer, in a spinal nerve ligation model. Methods: We made the rat neuropathic pain model by the ligation of the L5 spinal nerve. Intraperitoneal 4-methylcatechol ($10{\mu}g/kg$) or the same volume of saline wasadministrated twice daily just after the operation for 7 days. The tactile allodynia was measured by using von Frey filaments and its change was followed up from 3 days after SNL. The lumbosacral enlargement of the spinal cord was taken out and the mRNA contents of the ${\alpha}_2-adrenoceptor$ subtypes were measured by real time polymerase chain reaction and this was then compared with the control groups. The antiallodynic effect of intrathecal clonidine (3, 10, $30{\mu}g$) was evaluated and compared in the 4-methylcatechol treated rats and the control rats. Results: The expression of the ${\alpha}_{2A}$ and ${\alpha}_{2C}$ adrenoceptor subtypes did not change after 4-methylcatechol treatment. Intrathecal clonidine showed an earlier and better effect at the highest dose ($30{\mu}g$ intrathecal), but not with any other doses. Conclusions: Chronic intraperitoneal administration of 4-methylcatechol may improve the effect of intrathecal clonidine, but we could not prove the increase of ${\alpha}_{2A}$ and ${\alpha}_{2C}$ adrenoceptors in the spinal cord of 4-methylcatechol treated rats.

• 디자인학연구
• /
• 제19권3호
• /
• pp.105-116
• /
• 2006

In product manufacturing industries, a recent issue is the green concept. The green concept is a complicated area. If the green concept is for products, its serious issues have to be criticized. Although the importance of the green concept has overflowed, its influences have not been disputed vigorously. So this study is to critic the serious issues of the green concept in aesthetics in product design, manufacturing, and products' prices. The green environment has four representative elements: systems, policies, minds, and technologies, but they are not in the field of design. An element of the green concept, green design is also a sub concept for design, so it should be based on aesthetics. It is green aesthetics. But since green design first appeared, it has never approached by aesthetics because it has mostly had social meanings and expectations. So for green aesthetics, to think about what makes a product, and what can be aesthetic issues among them are important. Products consist of form, structure, material, and technology. Form means different shapes in a structure, but there cannot be any specific directions for a green concept. Structure has two kinds: interior and exterior structure. While interior structure has a technological character, exterior structure is deeply related with aesthetics, but it has also no chance for green concept. Material can be divided as two also: aesthetic and technological. Aesthetics materials mean the colors, opacity, and tactile sense of materials, but they are not aesthetic issues. Technological materials are recycled materials or non-recycled materials. Even if recycled materials are used today, they are close to systems or policies rather than aesthetics. With this result, green aesthetics is a very difficult concept. Second, green products are usually 30% more expensive than general products. But every consumer has his or her own economical conditions, and nobody can coerce consumers into buying expensive green products for green environments. And green products without good quality cannot satisfy consumers. This means that green concept is not accomplished by just manufacturing green products. Third, although a lot of proposals have appeared as green design in exhibitions, most of them are close to craft because they are so hard to be manufactured. Manufacturing is the first consideration for products. These three issues are enough to explain why green concept is complicated in manufacturing products. If they are not solved, the green concept is just a fiction. So if this study proposes a turning point against blind green-oriented atmosphere, it will be meaningful enough.

• 대한약리학회지
• /
• 제32권3호
• /
• pp.293-300
• /
• 1996

흰쥐에 thioacetamide(TAA)를 투여하면 간성뇌장애가 유발된다. 두가지 행동 상태(꼬리 접촉자극 및 미자극)와 세 단계의 신경학적 이상의 단계(정상, 약한 운동실조, 심한 운동실조)별로 뇌파를 기록하였고, 뇌파 스펙트럼 및 대역 분석을 통하여 간성뇌장애 진행동안 뇌파의 정량적인 변동을 관찰하였다. 정상 쥐에서 자극은 $theta(3.5{\sim}8\;Hz)$ 및 $gamma(30{\sim}50\;Hz)$ 대역의 power을 증가시켰다. 운동실조가 있는 쥐에서 이러한 변화가 일어나지 못하였다. 꼬리 자극을 하는 상태에서 theta 대역의 변화는 gamma 대역의 변화 보다 더욱 일찍 관찰되었다. 신경학적 행동 단계가 심해짐에 따라서 $beta3(21{\sim}30\;Hz)$ 및 gamma 대역에서 power가 점차적으로 감소하였다. 또한 간성뇌장애의 신경학적 증상은 benzodiazepine계 물질에 의하여 야기된다는 가설이 있으므로 beta power의 증가가 관찰될 것으로 기대하였으나 이 연구에서는 관찰하지 못하였다. 이 결과들로 미루어 볼때 이 연구에 사용된 스펙트럼 및 대역 분석이 간성뇌장애동안 신경학적 증상의 정도를 정량화 할 수 있다고 생각된다.

• 대한의용생체공학회:의공학회지
• /
• 제28권1호
• /
• pp.46-54
• /
• 2007

Objective: The first aim of this study is to determine the effects of acupuncture on the autonomic nervous system (ANS) via Heart Rate (HR) and Pupil Size (PS), and to compare the effects of acupuncture on the subjects' ANS when they are in a sitting position with the effects when they are in a supine position. Methods: Ten healthy male subjects were randomized to receive either verum acupuncture stimulation in a sitting position (SitV), verum acupuncture stimulation in a supine position (SupV), sham acupuncture stimulation in a sitting position (SitS), and sham acupuncture stimulation in a supine position (SupS). Acupuncture stimulation was applied to Neguan point (PC6) on the forearm. The subject's electrocardiogram (ECG) and pupil size were recorded continuously from 5 min before stimulation to 12 min after stimulation. Results: Verum and sham acupuncture stimulation were found to have reduced heart rate (p<0.01) and to have increased pupil size (p<0.01) in all the subjects. But when the reduction in HR and the increment in PS after verum acupuncture stimulation (both sitting and supine position) were compared with those after sham acupuncture stimulation, it was found that the reduction in HR (74.48 and 73.47 bpm, p<0.063) and the increment of PS (7.32 and, 6.10 mm, p<0.001) after verum acupuncture stimulation were greater than those after sham acupuncture stimulation, and that the corresponding values were statistically significant. In addition, at the baseline, it was found that the subjects had a larger PS and a faster HR in a sitting position than when they did so in a supine position. And then the reduction and increment ratio in the subject's HR and PS when they underwent acupuncture stimulation in a sitting position was significantly different from the reduction and increment in their HR and PS when they underwent the procedure in a supine position-i.e., the reduction ratio in HR was greater when they underwent the procedure in a sitting position, and such reduction ratio was statistically significant (p<0.05). As for the increment in PS, it was greater when the subjects underwent the procedure in a supine position, and such increment was significant (p<0.05). Conclusion: Manual acupuncture stimulation on Neguan point (PC6) has more significant influence on the autonomic nervous system rather than sham acupuncture (tactile stimulation). And the position-induced different states of ANS have different influence on the acupuncture effect.

• 감성과학
• /
• 제16권2호
• /
• pp.207-220
• /
• 2013

영상실감증대를 위한 시각, 청각, 촉각정보의 제시방식에 대해서는 많은 진보가 이루어 졌다. 반면 후각은 정의하기 어렵고 다루기 까다롭기 때문에 관련연구를 찾아보기 어렵다. 본 연구에서는 후각정보를 통한 영상실감증대 연구의 첫걸음으로 후각정보에 대한 사용자 수용도를 조사한 후 이에 근거하여 다양한 영상을 분류하였다. 이를 위해 먼저 영상에 냄새가 존재하는지 (냄새존재여부), 그 냄새가 실감을 증대시키는지 (실감증대효과), 영상과 함께 해당 냄새를 경험하고 싶은지 (냄새제시선호)라는 세가지 질문을 선정하였다. 각 질문들에 높은 혹은 낮은 점수를 받을 만한 다양한 장르의 영상 (51)개를 수집한 후, 참가자들에게 하나씩 영상을 시청하게 한 후 위의 세가지 질문에 대해 7점 척도로 평정하게 하였다. 영상분류를 위해 두 질문씩 쌍으로 묶어 각 질문의 척도를 2차원 평면의 X, Y축으로 설정한 후 평정값을 이용하여 영상분류를 위한 산포도를 구성하였다. 2차원 평면의 서로 다른 사분면에 위치한 영상군집들은 영상실감증대를 위한 후각정보 제시에 중요한 시사점을 줄 것으로 기대한다.

• 한국응용과학기술학회지
• /
• 제35권1호
• /
• pp.299-305
• /
• 2018

지각이란 다양한 감각기관을 통하여 시각, 청각, 촉각, 후각 등 주위 환경에 대한 정보를 습득하는 과정으로 뇌에 전달된 정보를 통합하고 해석하는 것을 의미한다. 이러한 지각된 정보를 바탕으로 상황에 적합한 정보를 효율적으로 사용하는 능력을 지각기술(perceptual skill)이라 하며, 스포츠에서 지각기술은 경기력 향상을 위한 중요한 요소로 작용한다. 따라서 많은 연구자들은 지각기술을 극대화하기 위하여 다양한 방법의 지각기술훈련 프로그램을 개발하고, 그 효과를 검증하려는 시도들이 진행되고 있다. 본 연구에서 소개하고 있는 지각기술훈련은 시지각에 중점을 둔 훈련 방법으로 미국이나 유럽에서 스포츠 경기력 향상을 위해 적용하는 훈련프로그램이다. 축구 페널티킥 상황에서 골키퍼에게 키커의 중요 단서(키커의 엉덩이-몸통, 발의 각도)를 바탕으로 지각기술훈련을 실시한 결과, 볼의 방향 예측 능력이 향상되었고, 테니스에서도 서버의 중요 단서(자세, 공, 라켓)에 대한 지각기술훈련을 실시한 결과, 서브 방향에 대한 예측능력이 향상되었다. 최근 지각기술훈련에 대한 연구가 활발하게 진행되고 있지만 아직까지는 연구의 수가 많지 않으며, 대부분이 실험실 상황에서의 연구로 실제 경기 상황에서의 활용에 대한 연구가 부족한 실정이다. 따라서 연구자들은 스포츠 경기력 향상을 위하여 지각기술훈련의 필요성을 검토하고, 그 효과에 대한 연구 방향을 포괄적으로 검토해 보는 시도가 필요하다.

• 한국콘텐츠학회논문지
• /
• 제7권5호
• /
• pp.102-109
• /
• 2007

회화에서 프레임의 미학을 연구하는 것보다 애니메이션 화면구성에 대한 프레임을 분석하는 것은 더욱 더 중요한 의미를 지니고 있다. 단편 애니메이션작가 조르주 슈피츠게벨의 이미지 형상은 캐릭터를 지우는 흔적을 통하여 작가 신체의 촉각적 감각으로 형상화된 구체적인 표현이라고 말할 수 있다. 이는 들뢰즈가 언급한 형상지우기에 의한 흔적의 변형(메타모포시스 Metamorphosis)과 비유된다. 애니메이션에서 살아 숨쉬는 캐릭터는 들뢰즈가 기술한 형상과 같이 실사영상과는 구별된다. 애니메이션은 프레임 안에서 움직이는 캐릭터의 형상과 큰 움직임이 없는 배경으로 나눠질 수 있는데, 움직이지 않는 배경의 구성은 들뢰즈가 언급한 아플라와 유사한 성격을 갖는다. 이는 실사영상을 프레임 단위로 기록하는 영화와는 다르게 애니메이션은 실제와는 다른 경계인 아플라를 배경으로 표현하고 있으며, 캐릭터는 최소한의 구상성을 갖고 대상에 대한 형상의 일그러짐을 통하여 새로운 형상으로 재탄생되고 있다. 다음은 프레임의 시간지속에 대한 문제이다. 슈피츠게벨의 작품은 프레임과 프레임사이의 상관관계에 의하여 의미가 생성된다. 그의 작품에서는 프레임과 프레임 간의 구성에 따른 형상 묘사 자체가 프레임으로 구성된다. 이러한 과정을 통하여 슈비츠게벨의 작품은 각 프레임 사이에 연결되어 있는 개별 프레임이 새롭게 생성되는 대상의 형상을 묘사하고 있다. 이는 대상에 대한 지시체의 근본이 적용되지 않는 현대영화에서 극히 적게 찾아 볼 수 있다고 들뢰즈는 언급한다. 바꿔 말하면 슈비츠게벨의 작품은 현대영화의 특징을 갖춘 애니메이션으로 프레임과 프레임 사이의 형상을 묘사하고 있다. 이는 들뢰즈가 언급한 대상세계의 법칙과 논리에서 벗어나 이루어지는 크리스털적 묘사임을 알 수 있다.