• Proceedings of the PSK Conference
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• 2003.04a
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• pp.292.1-292.1
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• 2003

Purpose. To develop a new heterodisperse 650mg acetaminophen HPMC matrix tablet with biphasic sustained release profiles. Methods. Hydroxypropylmethylcellulose(HPMC) matrix tablets were prepared by wet-granulating drug with other excipients, followed by direct compression of the dried granule mixtures into tablet using a rotary tablet machine. (omitted)

• Journal of Pharmaceutical Investigation
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• v.27 no.4
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• pp.323-329
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• 1997

Ipriflavone is non-hormonal antiosteoporotic drug which inhibits bone resorption by reducing recruitment and/or differentiation of osteoclasts, and stimulates proliferation and differentiation of osteoblast, and also enhances calcitonin secretion in the presence of estrogen. Although some kinds of immediately-released preparation of ipriflavone are available in commercial market, in present study, we tried to formulate sustained-release tablet using coating method with hydrophobic and hydrophilic coating materials. In vitro dissolution test was applied to evaluate sustained-release patterns of several test preparations (Test tablet A, B and C) designed using different preparation method or different compositions. From the results of dissolution test, test tablet A which showed suitable dissolution profile was selected as the candidate of new product. Pharmacokinetic evaluation of test drug, ipriflavone sustained-release tablets, was conducted in 6 beagle dogs weighing $11.5{\pm}0.5\;Kg$ compared with $Theobon^{\circledR}$ tablet, immediately-released tablet (Kukjae Pharm. Co.) as reference drug. Two products were randomly administered to 6 beagle dogs, and after 1 week, cross-over study was conducted. From the present study, AUC and $T_{max}$ of test product were significantly different from those of reference product (p<0.05), respectively$(AUC\;:\;3646.28{\pm}472.56\;vs\;3646.28{\pm}472.56\;ng{\cdot}hr/ml,\;T_{max}\;:\;4.33{\pm}1.03\;vs\;1.42{\pm}0.38\;hr)$. But $C_{max}$ was not significantly different between two products (p>0.05) $(\;512.52{\pm}48.18\;vs\;443.97{\pm}140.53\;ng/ml)$. From the results of pharmacokinetic evaluations, it was noted that absorption amount of test product was increased, but absorption rate was delayed and $C_{max}$ of two products were not changed. And it was concluded that redesign of the sustained-release preparation which has a lower content of iprifavone rather than test tablet A must be considered.

• Journal of Environmental Health Sciences
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• v.39 no.4
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• pp.376-382
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• 2013

Objectives: The objectives of this study were to identify the virucidal efficacy against the viral hemorrhagic septicemia virus (VHSV) of an aquatic disinfectant tablet composed of calcium hypochlorite. Methods: Virucidal efficacy was determined through the viability of VHSV contacted with the disinfectant in a viral stock cultured in a fathead minnow cell line. An aquatic disinfectant tablet and VHSV were reacted under distilled water (DW), hard water (HW) or organic matter suspension (OM) conditions. Results: Under DW and HW conditions, VHSV was inactivated with 24,000- and 2000-fold dilutions of the aquatic disinfectant tablet, respectively. With the investigation of the antiviral effect of the disinfectant under OM conditions, VHSV was inactivated with a 16,000-fold dilution of the aquatic disinfectant tablet. Conclusions: The results from this study showed that the aquatic disinfectant tablet was a highly effective disinfectant against VHSV. In the future, a controlled field trial is required to determine whether the use of an aquatic disinfectant tablet will be able to reduce VHSV in a cultured marine fish farm.

• Journal of The Korean Association of Information Education
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• v.9 no.3
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• pp.463-472
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• 2005

The purpose of the paper was to investigate students' perceptions of tablet computer-based mobile learning in a middle school. We examined the perceptions in terms of: 1) learning effectiveness, which refers to the effects of tablet computer on learning outcomes such as the grade; 2) attitude change, which is the change of students' attitudes and study habit; 3) learning activities, which refers to the kinds of learning activities using tablet computer; and 4) computer utilization, which is the ways of computer use in the study. The result showed that, in general, tablet computer affected all four types of perceptions positively.

• Biomedical Science Letters
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• v.8 no.2
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• pp.101-106
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• 2002

The purpose of this study was to test the capacity of automatic tablet crusher. The Automatic tablet crusher not only saved crushing time, but also removed floating fine powders that was occurred during crushing and caused allergy. The characteristics of powder produced by this crusher were as follows: First, to meet the condition as powder after pulverizing 5∼10 g tablet it took 6 to 12 seconds crushing time. But six seconds would do to get powder f3r oral administration. Second, when the quantity of medicine was measured by HPLC, powder from automatic crusher showed higher than that from pestle. HPLC chromatogram indicated that there was no change of medicine in the process of pulverization.

• Korean Management Science Review
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• v.28 no.1
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• pp.25-42
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• 2011

The mobile industry is the key foundation of digital convergence, and its constant growth is expected. Among mobile industries, new products leading the development of devices are the Emerging Device. This study is conducted to find out factors making differentiated by comparing the structural equation model(SEM) of the Tablet PC and the e-Book Reader. The main findings are as follows. First, the application of TAM to the Emerging Device shows that fitness of the model is generally high but the effect of Perceived Ease of Use has not been verified or found insignificant. Second, the acceptance model of the Tablet PC and the e-Book Reader has found that playfulness stimulates acceptance intentions. Third, the cost level of the Emerging Device acceptance model is not a factor stimulating consumers' acceptance intentions. Fourth, product attributes of the Tablet PC and the e-Book Reader to differentiate themselves from the other device are Functionality and Playfulness respectively.

• Journal of Pharmaceutical Investigation
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• v.40 no.3
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• pp.161-166
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• 2010

A fast dissolving tablet was developed using the freeze-drying technique. Hyeonggaeyeongyotang was selected as a model oriental medicine. Formulation and processing parameters were studied to obtain freeze-dried tablet with high drug loading, good palatability, and fast disintegration time. $Kollidon^{(R)}$ CLM served as both matrix former and taste masking agent. Ethanol used as co-solvent, decreased the disintegration time of tablet. Aspartame was employed to impart better taste. Drying condition was found to have a major effect in the morphology of the tablets. Freeze-drying process was optimized to decrease the processing time and improve the appearance of the tablets.

• Journal of architectural history
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• v.26 no.6
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• pp.55-66
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• 2017

This study attempted to analyze how dancheong for palace tablets during the Joseon period was designed as related to what plans and what materials were being used. It also investigated how this unique culture formed. The results found the following: First, the tablet dancheong unveiled through literature was designed using diverse techniques such as jinchae and yeokcheongchil. In jinchae, shell powder was applied to the tablet as the first lacquering, and then was colored. Second, in lacquer, maechil, chaesaekchil and jeohyeoptaechil were used. In yeokcheongchil, vegetable black, oil ash and perilla oil were applied to bitumen. Third, during the Joseon Dynasty, dancheong was applied to a tablet after first lacquering just like the danpihoe lacquering of Jiangsu Sheng, China. This tablet dancheong technique was developed based on a unique Korean lacquering culture that had been handed down from ancient times.

• YAKHAK HOEJI
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• v.20 no.1
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• pp.63-69
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• 1976

Prednisolone tablet product design problem was structured as constrained optimization problem and subsequently solved by multiple regression analysis and Lagrangian method of optimixation. Prednisolone was the drug chosen and anhydrous lactose and corn starch were the adjuvants. The effect of anhydrous lactose and corn starch concentrations on tablet hardness, volume, disintegration time and in vitro release rate was studied. The concentrations of anhydrous lactose and corn starch used in this experiment were 30-60 percent and 5-30 percent, respectively. A full second-order (quadratic) model with all possible two-factor interactions was employed. To obtain the values of anhydrous lactose and corn starch which miniumize the in vitro : release time (t$_{60%}$) subject to the constraint on tablet hardness, disintegration time and volume, we solved the Lagrange function. Multiple correlation coefficients for the regression models were correlated at less than 0.05 level and it was found that the optimum concentrations of anhydrous lactose and corn starch were 45 percent and 21 percent, respectively.

• The Journal of Information Systems
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• v.24 no.2
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• pp.117-138
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• 2015

Purpose The number of Tablet PC users has recently increased in steep, which started to offer media companies more opportunities to enter into a new business field. Based on Information System Success model, this study finds that tablet magazine's quality factors influence perceived usefulness, user satisfaction and intention of continuous use. Design/methodology/approach We conducted a survey for 20-40's Tablet PC users. After pilot study, we analyzed the main survey data by using SPSS 18.0 and AMOS 18.0, and employed structural equation modeling to test the hypotheses. Findings Our research results are summarized as follows : First, information quality has a positive impact on user satisfaction, but not on perceived usefulness. Second, service quality has a positive impact on perceived usefulness, but not on user satisfaction. Third, perceived usefulness positively influences user satisfaction. Fourth, user satisfaction positively influences the intention of continuous use. In particular we found that Tablet PC usage experience had a moderating effect on the relationship between perceived usefulness and user satisfaction.