• 제목/요약/키워드: t-FA

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삼차원 마이크로광조형 기술 응용을 위한 광경화 수지 EA1260T의 경화특성 조절에 대한 연구 (Modification of the curing characteristics of the photocurable resin FA1260T for 3D microfabrication using microstereolithography)

  • 김성훈;정대준;주재영;정성호
    • 한국정밀공학회지
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    • 제23권6호
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    • pp.174-179
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    • 2006
  • The curing characteristics of a photocurable resin are critical factors that often decide the ultimate resolution and structural sharpness of a final product fabricated by microstereolithography$(\mu-STL)$. In this study, we investigated the curing characteristics of the FA1260T photopolymer under a visible laser light of 42nm wavelength. Modification of the curing property of the FA1260T is attempted to reduce the cure depth $(D_c)$ by adding a radical quencher to the resin. Also, an organic solvent was used to reduce the resin viscosity for an improvement of the flatness of the liquid surface during layer-by-layer curing. As a result, the minimum $D_c$ has been reduced over a factor of 3 with no abrupt increase. Samples of three dimensional microstructures fabricated using the modified FA1260T are presented.

연신 및 열처리 조건이 PET film의 미세구조에 미치는 영향 (The Effect of Drawing and Annealing Condition on the Fine Structure of PET Film)

  • Park, Jong-Bum;Choi, Suk-Chui;Cho, Hyun-Hok
    • 한국염색가공학회지
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    • 제3권1호
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    • pp.8-16
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    • 1991
  • In order to investigate the fine structure of PET films, PET films were stretchd at various draw ratios (2, 3, 4, 5) below $T_g$ ($72^{\circ}C$) and then annealed at various temperatures (125, 150, 175, $200^{\circ}C$) under free-annealed (FA) and taut-annealed (TA) conditions. Such changes as thermal shrinkage, crystallinity, crystallite size, dynamic viscoelasticity and thermal behaviour were measured in relation to the draw ratio and annealing condition.The following results were obtained. 1. Thermal shirinkage increased with increasing annealing temperature and draw ratio, but decreased in case of draw ratio 4 (draw ratio 3 at $200^{\circ}C$) and above it. 2. The degree of crystallinity of FA samples were higher than those of TA samples. 3. Tan 5 of TA samples were less than those of FA samples, and storage moduli (E') and loss moduli (E") of FA samples were less than those of TA samples; moreover, maximum tan '||'&'||' temperature of FA samples were shifted toward higher temperature than those of TA samples. 4. The melting endotherm ($T_m$) and heat of fusion $(\DeltaH)$ of the PET film increased with the draw ratio and annealing temperature; in addition, premelting endotherm ($T_m$) and heat of fusion $(\DeltaH)$ of the local crystallization in the FA samples were larger than those of TA samples. 5. The X-ray diffraction pattern displayed sharp peaks gradually with the draw ratio and annealing temperature. 6. Crystallite sizes of FA samples were larger than those of TA samples.

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미강 페놀산 농축물과 Hydroxycinnamic Acids의 세포내 항당뇨 및 항산화 활성 (Anti-hyperglycemic and Antioxidative Activities of Phenolic Acid Concentrates of Rice Bran and Hydroxycinnamic Acids in Cell Assays)

  • 정은희;하태열;황인경
    • 한국식품영양학회지
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    • 제23권2호
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    • pp.233-239
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    • 2010
  • Phenolic acid concentrates of rice bran(RB-ex) and hydroxycinnamic acids were investigated for their anti-hyperglycemic activities through glucose uptake and glucokinase activity using HepG2 cells and stimulatory effects on insulin secretion using HIT-T15 cells. RB-ex was prepared as an ethylacetate extract after alkaline hydrolysis and hydroxycinnamic acids, found as major compositions of RB-ex, such as ferulic acid(FA), sinapic acid(SA) and p-coumaric acid(p-CA) were investigated to compare with the properties of RB-ex. The properties of glucose uptake in HepG2 cells were examined in the absence of insulin and two different glucose concentrations(5.5 mM and 25 mM). RB-ex and FA showed anti-hyperglycemic activities through the increase of glucose uptake and the stimulation of glucokinase activity in HepG2 cells. RB-ex exhibited higher glucose uptakes with higher glucose concentrations, whereas FA exhibited the same increasing effects on both concentrations of glucose. RB-ex and FA exhibited doubled glucokinase activities relative to control. In the presence of insulin in the 25 mM glucose-containing medium, the levels of glucose uptake were increased in all treatments compared with control. As stimulatory effects of samples on insulin secretion were estimated, RB-ex and FA stimulated insulin secretion at a concentration of 25 ${\mu}g/m{\ell}$ and in particular, FA showed the highest amount of insulin-release in HIT-T15 cells. Antioxidative effects on HIT-T15 cells, RB-ex and hydroxycinnamic acids, excluding p-CA, showed inhibitory activities of 78% to 80% at a concentration of 100 ${\mu}g/m{\ell}$. On the basis of these results, we conclude that RB-ex and FA could help decrease blood glucose levels and prevent the cell damages via antioxidant activity.

계층적 지역 등록 Mobile IP에서 백업 FA를 이용한 장애 관리 구조 (A Fault Management Architecture Using Backup FA in Hierarchical Local Registration Mobile IP)

  • 임기운;홍충선;이대영
    • 한국통신학회논문지
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    • 제26권11C호
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    • pp.1-9
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    • 2001
  • Mobile IP 프로토콜은 IP 호스트들이 IP 주소의 변화 없이 다른 네트워크 사이를 이동하는 것을 지원해준다. 지역 등록을 지원하는 Mobile IP 시스템은 비교적 먼 곳에 위치한 Home Agent로의 홈 등록 메시지의 빈도를 줄이기 위해 제안되어졌다. 이 지역 등록 Mobile IP 프로토콜은 MN의 등록 요청을 가려내 에이젼트가 처리함으로 성능 향상을 가져온다. 그러나 지역 등록 Mobile IP 접근 방법은 FA 장애 극복과 같은 몇 가지 고려해야 문제점을 가지게 된다. 본 논문에서는 계층적 지역 등록 Mobile IP에서 FA의 장애 극복하기 위한 기존의 프로토콜에 대해 살펴보고 계층적 지역 등록 Mobile IP에서 백업 FA에 의해 FA의 장애를 효율적으로 극복하는 새로운 FA 장애 극복 프로토콜에 대해 제안한다.

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Effect of Phytogenic Feed Additives in Soybean Meal on In vitro Swine Fermentation for Odor Reduction and Bacterial Community Comparison

  • Alam, M.J.;Mamuad, L.L.;Kim, S.H.;Jeong, C.D.;Sung, H.G.;Cho, S.B.;Jeon, C.O.;Lee, K.;Lee, Sang Suk
    • Asian-Australasian Journal of Animal Sciences
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    • 제26권2호
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    • pp.266-274
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    • 2013
  • The effect of different phytogenic feed additives on reducing odorous compounds in swine was investigated using in vitro fermentation and analyzed their microbial communities. Soybean meal (1%) added with 0.1% different phytogenic feed additives (FA) were in vitro fermented using swine fecal slurries and anaerobically incubated for 12 and 24 h. The phytogenic FAs used were red ginseng barn powder (Panax ginseng C. A. Meyer, FA1), persimmon leaf powder (Diospyros virginiana L., FA2), ginkgo leaf powder (Ginkgo biloba L., FA3), and oregano lippia seed oil extract (Lippia graveolens Kunth, OL, FA4). Total gas production, pH, ammonianitrogen ($NH_3$-N), hydrogen sulfide ($H_2S$), nitrite-nitrogen ($NO_2{^-}$-N), nitrate-nitrogen ($NO_3{^-}$-N), sulfate (${SO_4}^{--}$), volatile fatty acids (VFA) and other metabolites concentration were determined. Microbial communities were also analyzed using 16S rRNA DGGE. Results showed that the pH values on all treatments increased as incubation time became longer except for FA4 where it decreased. Moreover, FA4 incubated for 12 and 24 h was not detected in $NH_3$-N and $H_2S$. Addition of FAs decreased (p<0.05) propionate production but increased (p<0.05) the total VFA production. Ten 16S rRNA DGGE bands were identified which ranged from 96 to 100% identity which were mostly isolated from the intestine. Similarity index showed three clearly different clusters: I (FA2 and FA3), II (Con and FA1), and III (FA4). Dominant bands which were identified closest to Eubacterium limosum (ATCC 8486T), Uncultured bacterium clone PF6641 and Streptococcus lutetiensis (CIP 106849T) were present only in the FA4 treatment group and were not found in other groups. FA4 had a different bacterial diversity compared to control and other treatments and thus explains having lowest odorous compounds. Addition of FA4 to an enriched protein feed source for growing swine may effectively reduce odorous compounds which are typically associated with swine production.

FA-50 개발요구도의 효율적 관리를 위한 추적성 구현 (Efficient Management of FA-50 Development Requirements Through Traceability Implementation)

  • 김도현;김성준;안상석;이강훈;장민영
    • 시스템엔지니어링학술지
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    • 제6권2호
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    • pp.7-14
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    • 2010
  • Systematic and efficient Management of Development requirements will lead to success of project such as aircraft system development consisting of complex subsystem. For such reason, Requirements management tools have been used in most of project. In the case of FA-50 development project, requirements management tools have been used for systematic and efficient management of FA-50 Requirements. Especially FA-50 system was designed on the basis of the TA-50 configuration. Therefore, it needs traceability of requirements about functions, which have been already developed and will be newly developed. This paper was described about the implementation method of FA-50 development requirements traceability management.

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뇌 확산텐서 자기공명영상을 이용한 청소년 인터넷 중독자의 백질 섬유로에 관한 연구 (A Study of Whiter Matter Fiber Tractography in Young Internet Addiction Disorder using a Brain Diffusion Tensor Magnetic Resonance Imaging)

  • 구은회
    • 한국방사선학회논문지
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    • 제10권1호
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    • pp.7-13
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    • 2016
  • 3.0 T 자기공명영상기기에서 확산텐서영상을 이용하여 청소년을 대상으로 정상인과 인터넷 중독자의 뇌량과 내섬유막 구조의 변화에 대하여 정량적으로 알아보고자 하였다. 10명의 인터넷 중독자와 정상인 12명을 대상으로 검사를 하였고, 정량적 분석을 위하여 뇌량의 5부위와 내섬유막의 2부위를 View Forum 프로그램을 이용하여 두 그룹에 대한 신경섬유의 손상 정도를 FA, ADC($10^{-3}mm^2/s$), Length(mm)값으로 측정하였다. 그룹 간 통계적 유의성은 Independent t-test와 pearson 상관관계로 하였다(p<0.05). 정상인과 인터넷 중 독자에 관하여 신경섬유 손상정도는 7부위에 대하여 FA, ADC($10^{-3}mm^2/s$), Length(mm)값에 대하여 의미 있는 차이를 보였다(p<0.05). 또한 두 그룹에서 IAD scale 과 뇌량의 FA값은 음의 적으로 강하게 상관관계가 있었다(p<0.000). 결론적으로, 확산텐서영상은 FA, ADC($10^{-3}mm^2/s$), Length(mm)값에 대하여 유의성 있는 차이를 보여고, 이 결과는 뇌 백질에 대한 손상정도에 관하여 정량적으로 임상적 정보를 제공하였다.

Interactions Between MTHFR C677T - A1298C Variants and Folic Acid Deficiency Affect Breast Cancer Risk in a Chinese Population

  • Wu, Xia-Yu;Ni, Juan;Xu, Wei-Jiang;Zhou, Tao;Wang, Xu
    • Asian Pacific Journal of Cancer Prevention
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    • 제13권5호
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    • pp.2199-2206
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    • 2012
  • Background: Our objective was to evaluate the MTHFR C677T-A1298C polymorphisms in patients with breast cancer and in individuals with no history of cancer, to compare the levels of genetic damage and apoptosis under folic acid (FA) deficiency between patients and controls, and to assess associations with breast cancer. Methods: Genetic damage was marked by micronucleated binucleated cells (MNBN) and apoptosis was estimated by cytokinesis-block micronucleus assay (CBMN). PCR-RFLP molecular analysis was carried out. Results: The results showed significant associations between the MTHFR 677TT or the combined MTHFR C677T-A1298C and breast cancer risk (OR = 2.51, CI = 0.85 to 7.37, p = 0.08; OR = 4.11, CI = 0.78 to 21.8, p < 0.001). The MNBN from the combined MTHFR C677T-A1298C was higher and the apoptosis was lower than that of the single variants (p < 0.05). At 15 to 60 nmol/L FA, the MNBN in cases with the TTAC genotype was higher than controls (p < 0.05), whereas no significant difference in apoptosis was found between the cases and controls after excluding the genetic background. Conclusions: Associations between the combined MTHFR C677T-A1298C polymorphism and breast cancer are possible from this study. A dose of 120 nmol/L FA could enhance apoptosis in cases with MTHFR C677T-A1298C. Breast cancer individuals with the TTAC genotype may be more sensitive to the genotoxic effects of FA deficiency than controls.

External apical root resorption 6 months after initiation of orthodontic treatment: A randomized clinical trial comparing fixed appliances and orthodontic aligners

  • Toyokawa-Sperandio, Katia Cristina;Conti, Ana Claudia de Castro Ferreira;Fernandes, Thais Maria Freire;de Almeida-Pedrin, Renata Rodrigues;de Almeida, Marcio Rodrigues;Oltramari, Paula Vanessa Pedron
    • 대한치과교정학회지
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    • 제51권5호
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    • pp.329-336
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    • 2021
  • Objective: To compare the magnitude of external apical root resorption (EARR) 6 months after starting orthodontic treatment using orthodontic aligners (OAs) and fixed appliances (FAs). Methods: This parallel randomized clinical trial included 40 patients randomized into two groups: OA group (n = 20, 160 incisors) and FA group (n = 20, 160 incisors). For evaluation of the tooth length, periapical radiographs and standardized linear measurements of the maxillary and mandibular incisors were acquired before (T0) and 6 months after treatment initiation (T1). EARR was calculated through the difference in length between the two time points (T1-T0). Statistical comparisons were performed by means of using t-tests, chi-squared test and covariance analysis (a = 5%). Results: Rounding of the root apex was observed in both groups; the resorption involved 2.88% of the root length, so 97.12% of the tooth length remained intact. Intragroup comparisons between the two time points revealed a significant difference, with (T1-T0) ranging from -0.52 to -0.88 mm in the FA group and from -0.52 to -0.85 mm in the OA group. In the intergroup comparisons, only tooth #21 presented a statistically significant difference (OA: -0.52 ± 0.57 mm, FA: -0.86 ± 0.60 mm); however, the overall differences between groups were not clinically relevant, ranging from 0.03 to 0.35 mm. Conclusions: OA and FA treatment resulted in a similar degree of EARR in the maxillary and mandibular incisors at 6 months after treatment initiation. However, the amount of resorption was small and does not impair tooth longevity.

Identification and characterization of novel single nucleotide polymorphism markers for fat deposition in muscle tissue of pigs using amplified fragment length polymorphism

  • Supakankul, Pantaporn;Kumchoo, Tanavadee;Mekchay, Supamit
    • Asian-Australasian Journal of Animal Sciences
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    • 제30권3호
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    • pp.338-346
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    • 2017
  • Objective: This study was conducted to identify and evaluate the effective single nucleotide polymorphism (SNP) markers for fat deposition in the longissimus dorsi muscles of pigs using the amplified fragment length polymorphism (AFLP) approach. Methods: Sixty-four selective primer combinations were used to identify the AFLP markers in the 20 highest- and 20 lowest-intramuscular fat (IMF) content phenotypes. Five AFLP fragments were converted into simple codominant SNP markers. These SNP markers were tested in terms of their association with IMF content and fatty acid (FA) composition traits in 620 commercially crossbred pigs. Results: The SSC7 g.4937240C>G marker showed an association with IMF content (p<0.05). The SSC9 g.5496647_5496662insdel marker showed a significant association with IMF content and arachidonic levels (p<0.05). The SSC10 g.71225134G>A marker revealed an association with palmitoleic and ${\omega}9$ FA levels (p<0.05), while the SSC17 g.61976696G>T marker showed a significant association with IMF content and FA levels of palmitoleic, eicosenoic, arachidonic, monounsaturated fatty acids, and ${\omega}9$ FA levels. However, no significant association of SSC8 g.47338181G>A was observed with any IMF and FA levels in this study. Conclusion: Four SNP markers (SSC7 g.4937240C>G, SSC9 g.5496647_5496662insdel, SSC10 g.71225134G>A, and SSC17 g.61976696G>T) were found to be associated with IMF and/or FA content traits in commercially crossbred pigs. These findings provide evidence of the novel SNP markers as being potentially useful for selecting pigs with the desirable IMF content and FA composition.