• Title/Summary/Keyword: surrogate

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Separation for the Determination of $^{59/63}Ni$ in Radioactive Wastes (방사성 폐기물 내 $^{59/63}Ni$ 정량을 위한 분리)

  • Lee, Chang-Heon;Jung, Kie-Chul;Choi, Kwang-Soon;Jee, Kwang-Young;Kim, Won-Ho
    • Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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    • v.3 no.4
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    • pp.309-317
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    • 2005
  • A study on the separation of $^{99}Tc,\;^{94}Nb,\;^{55}Fe,\;^{90}Sr\;and\;^{59/63}Ni$ in various radioactive wastes discharged from nuclear power plants has been performed for a use in their quantification which is indispensible for the evaluation of the radionuclide inventory Ni was recovered along with Ca, Mg, Al, Cr, Ti, Mn, Ce, Na, K, and Cu through the sequential separation procedure of Re(as a surrogate of $^{99}Tc$), Nb, Fe and Sr by anion exchange and Sr-Spec extraction chromatography. In this research, chemical separation of Ni from the co-existing elements was investigated by cation exchange and Ni-Spec extraction chromatography. Precipitation behaviour of Ni and the co-existing elements with dimethylglyoxime(DMG) was investigated in ammonium $citrate/ethanol-H_2O$ and tartaric $acid/acetone-H_2O$ in order to purify separated Ni fractions and to prepare $^{59/63}Ni$ source for the radioactivity measurement using a gas proportional counter. Recovery of Ni separated through ion exchange chromatographic separation procedure was $92.1\%$ with relative standard deviation of $0.9\%$. In addition, recovery of Ni with DMG in the tartaric $acid/acetone-H_2O$ was $85.6\%$ with relative standard deviation of $1.9\%$.

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Estimation of surface-level PM2.5 concentration based on MODIS aerosol optical depth over Jeju, Korea (MODIS 자료의 에어로졸의 광학적 두께를 이용한 제주지역의 지표면 PM2.5 농도 추정)

  • Kim, Kwanchul;Lee, Dasom;Lee, Kwang-yul;Lee, Kwonho;Noh, Youngmin
    • Korean Journal of Remote Sensing
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    • v.32 no.5
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    • pp.413-421
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    • 2016
  • In this study, correlations between Moderate Resolution Imaging Spectroradiometer (MODIS) derived Aerosol Optical Depth (AOD) values and surface-level $PM_{2.5}$ concentrations at Gosan, Korea have been investigated. For this purpose, data from various instruments, such as satellite, sunphotometer, Optical Particle Counter (OPC), and Micro Pulse Lidar (MPL) on 14-24 October 2009 were used. Direct comparison between sunphotometer measured AOD and surface-level $PM_{2.5}$ concentrations showed a $R^2=0.48$. Since the AERONET L2.0 data has significant number of observations with high AOD values paired to low surface-level $PM_{2.5}$ values, which were believed to be the effect of thin cloud or Asian dust. Correlations between MODIS AOD and $PM_{2.5}$ concentration were increased by screening thin clouds and Asian dust cases by use of aerosol profile data on Micro-Pulse Lidar Network (MPLNet) as $R^2$ > 0.60. Our study clearly demonstrates that satellite derived AOD is a good surrogate for monitoring atmospheric PM concentration.

Usefulness of End-tidal Carbon Dioxide as a Predictor of Emergency Intervention in Major Trauma Patients (중증 외상 환자에서의 응급중재술 시행 예측 인자로서의 호기말 이산화탄소 분압의 유용성)

  • Kim, Sung Ho;Kim, Seunghwan;Lee, Jae Gil;Chung, Sung Phil;Kim, Seung Ho
    • Journal of Trauma and Injury
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    • v.27 no.4
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    • pp.133-138
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    • 2014
  • Purpose: If the survival of patients suffering from severe blunt trauma is to be improved, appropriate interventions should be taken immediately. The purpose of this study is to evaluate the clinical utility of end-tidal carbon dioxide ($ETCO_2$) as a surrogate marker for predicting both the need for intervention and the prognosis. Methods: This is a prospective observational study. Nasal cannula was applied to measure $ETCO_2$, and the following parameters, which are known to be related to the prognosis for a patient, were recorded: injury severity score (ISS), revised trauma score (RTS), arterial blood gas (ABG), lactate, and hemoglobin (Hb). To evaluate the outcome, we investigated the details of emergent interventions and expired patients. Results: A total of 93 patients were enrolled in this study. Emergent intervention was significantly associated with systolic blood pressure (sBP, p-value=0.001), $ETCO_2$ (p-value<0.001), serum lactate level (p-value<0.001), pH (p-value< 0.003), $HCO_3$ (p-value=0.004), base excess (p-value<0.002), ISS (p-value<0.001) and RTS (p-value=0.005). In the multivariate logistic regression, only $ETCO_2$ (odds ratio (OR): 0.897, 95% confidence interval (CI): 0.792-0.975, p-value= 0.048) and ISS (OR: 1.132, 95% CI: 1.053-1.233, p-value=0.002) were associated with emergent intervention whereas $ETCO_2$ (p-value=0.973) and ISS (p-value=0.511) were not statistically significant in predicting the survival of patients in the univariate analysis. An optimal ETCO cut-off of 29 mmHg on the ROC curve was determined, with the area under the ROC curve (AUC) being 0.824 (0.732-0.917)]. Conclusion: This study has revealed that $ETCO_2$, which can be rapid and easily measured through a nasal cannula, and the ISS may be prognostic indicators of emergent interventions in Emergency Departments.

The Statistical Correlation Between Continuous Driving Time and Drowsy Accidents (연속주행시간과 졸음사고간 통계적 상관관계 분석)

  • KIM, Ducknyung;KIM, Sujin;CHOI, Jaeheon;CHO, Jongseok
    • Journal of Korean Society of Transportation
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    • v.35 no.5
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    • pp.423-433
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    • 2017
  • During recent 5 years, it was recorded that 20% of total accident frequency and 30% of total number of death have been occurred due to drowsy driving. Drowsy driving accident is result from the loss of driving ability due to driver's accumulated fatigue. Continuous driving time can be measured as a surrogate variable to quantify the level of fatigue. The main purpose of this research is to investigate statistical correlation between the proportion of continuous driving vehicle (more than 2 hours) and the number of drowsy accidents. To carry this out, continuous driving time was measured using GPS route-guidance trajectory data. Also, accident frequency, traffic volume and segment length were collected to estimate safety performance function (SPF) for Jungbunearuk expressway in Korea. Through various types of estimated SPFs, statistical correlation was analyzed based on estimated statistical indices. This research can provide theoretical background for enforcement to regulate commercial vehicle driver's continuous driving time. In addition, throughout the trajectory data expansion, it is expected that strategy for anti-drowsy driving facilities installation can be established based on the suggested methodology.

Correlation Analysis of Signal to Noise Ratio (SNR) and Suspended Sediment Concentration (SSC) in Laboratory Conditions (실험수로에서 신호대잡음비와 부유사농도의 상관관계 분석)

  • Seo, Kanghyeon;Kim, Dongsu;Son, Geunsoo
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.37 no.5
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    • pp.775-786
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    • 2017
  • Monitoring sediment flux is crucial especially for maintaining river systems to understand morphological behaviors. Recently, hydroacoustic backscatter (or SNR) as a surrogate to empirically estimate suspended sediment concentration has been increasingly highlighted for more efficient acquisition of sediment dataset, which is difficult throughout direct sediment sampling. However, relevant contemporary researches have focused on wide range solution applicable for large natural rivers where H-ADCPs with relatively low acoustic frequency have been widely utilized to seamlessly measure streamflow discharge. In this regard, this study aimed at investigating hydroacoustical characteristics based on a very recently released H-ADCP (SonTek SL-3000) with high acoustic frequency of 3 MHz in order to capitalize its capacity to be applied for suspended sediment monitoring in laboratory conditions. SL-3000 was tested in a laboratory flume to collect SNR in conjunction with LISST-100X for actual sediment concentration and particle distribution in both sand and silt sediment injection in various amount. Conventional algorithms to correct signal attenuations for water and sediment were carefully tested to validate whether they can be applied for SL-3000. As result of analyzing the SNR-SSC correlation trand, through further study in the future, it is confirmed that SSC can be observed indirectly by using the SNR.

Comparative Inactivation of Hepatitis A Virus and Murine Encephalomyocarditis Virus to Various Inactivation Processes (바이러스 불활화 공정에 대한 Hepatitis A Virus와 Murine Encephalomyocarditis Virus의 민감도 비교)

  • Kim, In-Seop
    • Korean Journal of Microbiology
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    • v.39 no.4
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    • pp.242-247
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    • 2003
  • Murine encephalomyocarditis virus (EMCV) has been used as a surrogate for hepatitis A virus (HAV) for the validation of virus removal and/or inactivation during the manufacturing process of biopharmaceuticals. Recently international regulation for the validation of HAV safety has been reinforced because of the reported cases of HAV transmission to hemophiliac patients who had received ntihemophilic factors prepared from human plasma. The purpose of the present study was to compare the resistance of HAV and EMCV to various viral inactivation processes and then to standardize the HAV validation method. HAV was more resistant than EMCV to pasteurization (60oC heat treatment for 10 hr), low pH incubation (pH 3.9 at 25oC for 14 days), 0.1 M NaOH treatment, and lyophilization. EMCV was completely inactivated to undetectable levels within 2 hr of pasteurization, however, HAV was completely inactivated to undetectable levels after 5 hr treatment. EMCV was completely inactivated to undetectable levels within 15 min of 0.1 M NaOH treatment, however, residual infectivity of HAV still remained even after 120 min of treatment. The log reduction factors achieved during low pH incubation were 1.63 for HAV and 3.84 for EMCV. Also the log reduction factors achieved during a lyophilization process of antihemophilic factor VIII were 1.21 for HAV and 4.57 for EMCV. These results indicate that HAV rather than EMCV should be used for the virus validation study and the validation results obtained using EMCV should be precisely reviewed.

Selective Separation of $^{59/63}Ni$ from Radioactive Wastes (방사성 폐기물 내 $^{59/63}Ni$의 선택적 분리)

  • Lee Chang-Heon;Jung Kie-Chul;Choi Kwang-Soon;Jee Kwang-Yong;Kim Won-Ho
    • Proceedings of the Korean Radioactive Waste Society Conference
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    • 2005.06a
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    • pp.121-128
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    • 2005
  • A study on the selective separation of $^{99}Tc,\;^{94}Nb,\;^{55}Fe,\;^{90}Sr$ and $^{59}Ni(^{63}Ni)$ from various radioactive wastes discharged from the nuclear power plants in Korea is being performed for use in their quantifications which are indispensible for the evaluation of the radionuclide inventory. Separation behaviour of Ce, Ca, Mg, Al, Cr, Ti, Mn and Cu recovered along with Ni during the separation of Re (as a surrogate of $^{99}Tc$), Nb, Fe and Sr by anion exchange and Sr-Spec extraction chromatography was investigated by cation exchange and Ni-Spec extraction chromatography using synthetic radioactive waste dissolved solutions containing matrix elements such as Re, Nb, Fe, Sr, Ni, B, Na, K, Ce, Co, Ca, Mg, Al, Zn, Cr, Pb, Cd, Mo, Mn, Cu, Zr, Ti and U. To purify the Ni fraction recovered and prepare a radionuclide source available for gas proportional counting, an application of the Ni precipitation procedure with dimethylglyoxime in the medium of ammonium citrate and tartaric acid solutions as a masking agent for co-existing metal ions was described in detail.

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Assessment of River Water Quality Contaminated by Abandoned Mine and Hot-Spring using Principal Component Analysis (주성분분석기법을 적용한 온천 및 폐광산 오염원에 대한 하천수질평가)

  • Lee Jae-Young;Sato Yuko;Kang Meea;Jeong Gyo-Cheol
    • The Journal of Engineering Geology
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    • v.15 no.4 s.42
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    • pp.381-390
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    • 2005
  • S City depends on the T River as source water for water supply. Arsenic and boron from the hot-spring waste-water discharged from the hot-spring spa resort and emerging from the fractures of bedrock of the river have been prevalent contaminant of the T River water. This research was conducted to propose the simple and quick surrogate parameter for water quality management easily. And through making hexa-diagram of principal ions in the water samples, existing state of the water and influence of the human activity or geological origin can be figured out. As a results of characteristics of the T River water quality using principal component analysis, the contributory percentages of the 1st, 2nd and 3rd principal components were $40.80\%,\;21.40\%\;and\;11.31\%$, respectively. Therefore it was clarified that the quality of the T River water could be explained by these three principal components. Concentration of the chloride ion, which is one of the characteristics of the hot-spring water, was well correlated to both arsenic and boron concentrations. Hence concentrations of the arsenic and boron in the raw water of the water reatment plant can be predicted by the measurement of concentration of the chloride ion.

The Survey of High School Students' Concern Levels on Decision-making Problems based on Biology (생물영역에서 고등학생의 의사결정 문제에 대한 관심도 조사)

  • Hong, Jung-Lim;Chang, Nam-Kee
    • Journal of The Korean Association For Science Education
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    • v.19 no.1
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    • pp.1-7
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    • 1999
  • The purpose of this study was to survey the high school students' concern levels on decision-making problems based on biology, This study is a exploratory research to develop teaching strategies and curriculum of the common science for the enhancement of the students' decision-making ability in problems involved biological knowledges. The survey subjects were 101 first graders of the high school in Seoul area. The survey instrument developed was 5-point scale of Likert type consisted of 24 question items. The survey results showed that the concern level on selection of method for learning was the highest. The concern levels on selection of method for sports or diet which are the individual faced problems were high, and concern levels on the problems social issued such as decisions about standard for noise, pros and cons of approval for brain death or artificial abortion were high, too. The students' concern levels on problems individual context were significantly higher than concern levels on problems social context (p<0.01). The males' concern levels were higher than females' on 'AIDS', 'incinerator for rubbish', 'atomic power plant', 'protection policy for decreasing species', 'standard for noise' (p<0.05), And the males' concern levels were higher than females' on domain of 'ecosystem and environment pollution'. But the females had higher concern levels than males on 'diet' and 'surrogate mother' (p<0.05). The analyzed results were discussed in respects of implication for teaching strategies and curriculum.

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Use of Hydrogen Peroxide with Ozone to Simultaneously Reduce MIB and Quench Ozone Residual in Existing Water Treatment Plants Sourcing Water from the Han River (한강을 원수로 하는 오존/과산화수소 고도정수처리공정에서의 MIB제거 및 잔류오존 농도에 관한 연구)

  • McAdams, Stephen R.;Koo, Bon Jin;Jang, Myung Hoon;Lee, Sung Kyoo
    • Journal of Korean Society on Water Environment
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    • v.28 no.5
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    • pp.704-716
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    • 2012
  • This paper provides a detailed account of pilot testing conducted at South Lake Tahoe (California), the Ddukdo (Seoul) water treatment plant (WTP) and the Bokjung (Seongnam) WTP between February, 2010, and February, 2012. The objectives were first, to characterize the reactions of ozone with hydrogen peroxide (Peroxone) for Han River water following sand filtration, second to determine empirical ozone and hydrogen peroxide doses to remove a taste-and-odor surrogate 2-methylisoborneol (MIB) using an advanced oxidation process (AOP) configuration and third, to determine the optimum dosing configuration to reduce residual ozone to a safe level at the exit of the process. The testing was performed in a real-time plant environment at both low- and high seasonal water temperatures. Experimental results including ozone decomposition rates were dependent on temperature and pH, consistent with data reported by other researchers. MIB in post-sand-filtration water was spiked to 40-50 ng/L, and in all cases, it was reduced to below the specified target level (7 ng/liter) and typically non-detect (ND). It was demonstrated that Peroxone could achieve both MIB removal and low effluent ozone residual at ozone+hydrogen peroxide doses less than those for ozone alone. An empirical predictive model, suitable for use by design engineers and operating personnel and for incorporation in plant control systems was developed. Due to a significant reduction in the ozone reaction/decomposition at low winter temperatures, results demonstrate the hydrogen peroxide can be "pre-conditioned" in order to increase initial reaction rates and achieve lower ozone residuals. Results also indicate the method, location and composition of hydrogen peroxide injection is critical to successful implementation of Peroxone without using excessive chemicals or degrading performance.