• 제목/요약/키워드: surface acting

검색결과 561건 처리시간 0.027초

Consistent and Specific Suppression of Mucin Release from Cultured Hamster Tracheal Surface Epithelial Cells by Poly-L-Lysine

  • Lee, Choong-Jae;Lee, Jae-Heun;Seok, Jeong-Ho;Hur, Gang-Min;Park, Ji-Sun;Bae, So-Hyun;Jang, Hyeon-Seok;Park, Sang-Cheol
    • The Korean Journal of Physiology and Pharmacology
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    • 제7권3호
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    • pp.143-147
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    • 2003
  • Poly-L-lysine (PLL) was reported to suppress mucin release from airway goblet cells during 30 min treatment period. In this study, we investigated whether PLL consistently suppresses mucin release from cultured airway goblet cells during 24 h after 30 min treatment and also specifically suppresses the release of mucin without any effects on the other releasable glycoproteins. Confluent primary hamster tracheal surface epithelial (HTSE) cells were metabolically radiolabeled with $^3H$-glucosamine for 24 h and chased for 30 min in the presence of varying concentrations of PLL to assess the effects on $^3H$-mucin release and on the total elution profile of the treated culture medium. The total mucin content during 24 h after 30 min treatment of PLL was assesed to investigate the consistency of effects. PLL did not affect the release of the other releasable glycoproteins whose molecular weights were less than mucin, and decreased the total mucin content during 24 h after 30 min treatment. We conclude that PLL can specifically suppress mucin release from cultured airway goblet cells and the suppression on mucin release is consistent. This finding suggests that PLL might be used as a specific airway mucin-regulating agent by directly acting on airway mucin-secreting cells.

유막온도경계조건이 평행 슬라이더 베어링의 윤활성능에 미치는 영향 (Effect of Film-Temperature Boundary Conditions on the Lubrication Performance of Parallel Slider Bearing)

  • 박태조;김민규
    • Tribology and Lubricants
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    • 제33권5호
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    • pp.207-213
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    • 2017
  • In sliding bearings, viscous friction due to high shear acting on the bearing surface raises the oil temperature. One of the mechanisms responsible for generating the load-carrying capacity in parallel surfaces is known as the viscosity wedge effect. In this paper, we investigate the effect of film-temperature boundary conditions on the thermohydrodynamic (THD) lubrication of parallel slider bearings. For this purpose, the continuity equation, Navier-Stokes equation, and the energy equation with temperature-viscosity-density relations are numerically analyzed using the commercial computational fluid dynamics (CFD) code FLUENT. Two different film-temperature boundary conditions are adopted to investigate the pressure generation mechanism. The temperature and viscosity distributions in the film thickness and flow directions were obtained, and the factors related to the pressure generation in the equation of motion were examined in detail. It was confirmed that the temperature gradients in the film and flow directions contribute heavily to the thermal wedge effect, due to which parallel slider bearing can not only support a considerable load but also reduce the frictional force, and its effect is significantly changed with the film-temperature boundary conditions. The present results can be used as basic data for THD analysis of surface-textured sliding bearings; however, further studies on various film-temperature boundary conditions are required.

연료전지용 다공성전극에 있어서 백금촉매의 분산성개선 (Improvement of Platinum Particle Dispersion on Porous Electrode for Phosphoric Acid Fuel Cell)

  • 박정일;김조웅;이주성
    • 공업화학
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    • 제1권2호
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    • pp.224-231
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    • 1990
  • 백금촉매의 분산을 향상시키기 위하여 카본블랙의 표면처리, 용매, 계면활성제 및 초음파분산기에 따른 효과를 고찰하였다. 카본블랙을 산화처리하여 카본블랙 표면에 친수성기인 작용기들을 도입함으로써 작용기들이 염화백금산 이온의 anchorage center역할을 하여 이 염화백금산을 환원시킬 때 백금입자(이온)의 이동이나 성장을 억제시켜 미립화 시킬 수 있다고 생각되었다. 혼합용매, 계면활성제, 초음파분산기 등을 이용한 경우, 염화 백금산이온이 anchorage center 역할을 하고 있는 작용기들에 까지 잘 스며들어감으로써 백금촉매의 분산성이 향상됨을 알았다. 혼합용매에 초음파분산기를 사용하여 공기산화시킨 카본블랙에 백금촉매를 담지시킨 결과, 분산성이 가장 우수하였으며 입자크기는 $30A^{\circ}$ 이하로 미립화 되었다.

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이봉분포 마스터커브를 이용한 SA508 Gr. 3 원자로용기강의 파괴인성 평가 (Evaluation of Fracture Toughness for SA508 Gr. 3 Reactor Pressure Vessel Steel Using Bimodal Master Curve Approach)

  • 김종민;김민철;이봉상
    • 한국압력기기공학회 논문집
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    • 제13권2호
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    • pp.60-66
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    • 2017
  • The standard master curve (MC) approach has the major limitation because it is only applicable to homogeneous datasets. In nature, materials are macroscopically inhomogeneous and involve scatter of fracture toughness data due to various deterministic material inhomogeneity and random inhomogeneity. RPV(reactor pressure vessel) steel has different fracture toughness with varying distance from the inner surface of the wall due to cooling rate in manufacturing process; deterministic inhomogeneity. On the other hand, reference temperature, $T_0$, used in the evaluation of fracture toughness is acting as a random parameter in the evaluation of welding region; random inhomogeneity. In the present paper, four regions, the surface, 1/8T, 1/4T and 1/2T, were considered for fracture toughness specimens of KSNP (Korean Standard Nuclear Plant) SA508 Gr. 3 steel to investigate deterministic material inhomogeneity and random inhomogeneity. Fracture toughness tests were carried out for four regions and three test temperatures in the transition region. Fracture toughness evaluation was performed using the bimodal master curve (BMC) approach which is applicable to the inhomogeneous material. The results of the bimodal master curve analyses were compared with that of conventional master curve analyses. As a result, the bimodal master approach considering inhomogeneous materials provides better description of scatter in fracture toughness data than conventional master curve analysis. However, the difference in the $T_0$ determined by two master curve approaches was insignificant.

Nanostructured Metal Organic Framework Modified Glassy Carbon Electrode as a High Efficient Non-Enzymatic Amperometric Sensor for Electrochemical Detection of H2O2

  • Naseri, Maryam;Fotouhi, Lida;Ehsani, Ali
    • Journal of Electrochemical Science and Technology
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    • 제9권1호
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    • pp.28-36
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    • 2018
  • Metal-organic frameworks have recently been considered very promising modifiers in electrochemical analysis due to their unique characteristics among which tunable pore sizes, crystalline ordered structures, large surface areas and chemical tenability are worth noting. In the present research, $Cu(btec)_{0.5}DMF$ was electrodeposited on the surface of glassy carbon electrode at room temperature under cathodic potential and was initially used as the active materials for the detection of $H_2O_2$. The cyclic voltammogram of $Cu(btec)_{0.5}DMF$ modified GC electrode shows distinct redox peaks potentials at +0.002 and +0.212 V in 0.1 M phosphate buffer solution (pH 6.5) corresponding to $Cu^{(II)}/Cu^{(I)}$ in $Cu(btec)_{0.5}DMF$. Acting as the electrode materials of a non-enzymatic $H_2O_2$ biosensor, the $Cu(btec)_{0.5}DMF$ brings about a promising electrocatalytic performance. The high electrocatalytic activity of the $Cu(btec)_{0.5}DMF$ modified GC electrode is demonstrated by the amperometric response towards $H_2O_2$ reduction with a wide linear range from $5{\mu}M$ to $8000{\mu}M$, a low detection limit of $0.865{\mu}M$, good stability and high selectivity at an applied potential of -0.2 V, which was higher than some $H_2O_2$ biosensors.

Temperature dependence of the effective anisotropy in Ni nanowire arrays

  • Meneses, Fernando;Urreta, Silvia E.;Escrig, Juan;Bercoff, Paula G.
    • Current Applied Physics
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    • 제18권11호
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    • pp.1240-1247
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    • 2018
  • Magnetic hysteresis in Ni nanowire arrays grown by electrodeposition inside the pores of anodic alumina templates is studied as a function of temperature in the range between 5 K and 300 K. Nanowires with different diameters, aspect ratios, inter-wire distance in the array and surface condition (smooth and rough) are synthesized. These microstructure parameters are linked to the different free magnetic energy contributions determining coercivity and the controlling magnetization reversal mechanisms. Coercivity increases with temperature in arrays of nanowires with rough surfaces and small diameters -33 nm and 65 nm- when measured without removing the alumina template and/or the Al substrate. For thicker wires -200 nm in diameter and relatively smooth surfaces- measured without the Al substrate, coercivity decreases as temperature rises. These temperature dependences of magnetic hysteresis are described in terms of an effective magnetic anisotropy $K_a$, resulting from the interplay of magnetocrystalline, magnetoelastic and shape anisotropies, together with the magnetostatic interaction energy density between nanowires in the array. The experimentally determined coercive fields are compared with results of micromagnetic calculations, performed considering the magnetization reversal mode acting in each studied array and microstructure parameters. A method is proposed to roughly estimate the value of $K_a$ experimentally, from the hysteresis loops measured at different temperatures. These measured values are in agreement with theoretical calculations. The observed temperature dependence of coercivity does not arise from an intrinsic property of pure Ni but from the nanowires surface roughness and the way the array is measured, with or without the alumina template and/or the aluminum support.

Research on aerodynamic force and structural response of SLCT under wind-rain two-way coupling environment

  • Ke, Shitang;Yu, Wenlin;Ge, Yaojun
    • Wind and Structures
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    • 제29권4호
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    • pp.247-270
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    • 2019
  • Wind-resistant design of existing cooling tower structures overlooks the impacts of rainfall. However, rainstorm will influence aerodynamic force on the tower surface directly. Under this circumstance, the structural response of the super-large cooling tower (SLCT) will become more complicated, and then the stability and safety of SLCT will receive significant impact. In this paper, surrounding wind fields of the world highest (210 m) cooling tower in Northwest China underthree typical wind velocities were simulated based on the wind-rain two-way coupling algorithm. Next, wind-rain coupling synchronous iteration calculations were conducted under 9 different wind speed-rainfall intensity combinations by adding the discrete phase model (DPM). On this basis, the influencing laws of different wind speed-rainfall intensity combinations on wind-driving rain, adhesive force of rain drops and rain pressure coefficients were discussed. The acting mechanisms of speed line, turbulence energy strength as well as running speed and trajectory of rain drops on structural surface in the wind-rain coupling field were disclosed. Moreover, the fitting formula of wind-rain coupling equivalent pressure coefficient of the cooling tower was proposed. A systematic contrast analysis on its 3D distribution pattern was carried out. Finally, coupling model of SLCT under different working conditions was constructed by combining the finite element method. Structural response, buckling stability and local stability of SLCT under different wind velocities and wind speed-rainfall intensity combinations were compared and analyzed. Major research conclusions can provide references to determine loads of similar SLCT accurately under extremely complicated working conditions.

캐피라리 전기 영동법에 의한 비시안 무전해 Au 도금액의 분석 (Analysis of cyanide free electroless Au plating solution by capillary elecrophoresis)

  • 한재호;김동현
    • 한국표면공학회지
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    • 제55권2호
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    • pp.120-132
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    • 2022
  • In the non-cyanide-based electroless Au plating solution using thiomalic acid as a complexing agent and aminoethanethiol as a reducing agent, analysis of each component constituting the plating solution is essential for the analysis of the reaction mechanism. And component analysis in the plating solution is important for monitoring component changes in the plating process and optimizing the management method. Capillary Electrophoresis (CE) method is rapid, sensitive and quantitative and could be readily applied to analysis of Aun+ ion, complexing agent and reducing agent in electroless Au plating solution. In this study, the capillary electrophoresis method was used to analyze each component in the electroless Au plating solution in order to elucidate the complex bonding form and the plating mechanism of the non-cyanide-based electroless Au plating bath. The purpose of this study was to establish data for optimizing the monitoring and management method of plating solution components to improve the uniformity of precipitation and stability. As a result, it was confirmed that the analysis of thiomalic acid as a complexing agent and Aun+ ions and the analysis of aminoethanethiol as a reducing agent were possible by capillary electrophoresis. In the newly developed non-cyanide-based electroless Au plating solution, it was confirmed that Aun+ ions exist in the form of Au+ having a charge of +1, and that thiomalic acid and Au+ are combined in a molar ratio of 2 : 1. In addition, it was confirmed that aminoethanethiol can form a complex by combining with Au+ ions depending on conditions as well as acting as a reducing agent.

실 작업 부하를 이용한 로타베이터 기어박스의 강도 평가와 치면 접촉 패턴 해석 (Gear Rating and Contact Pattern Analysis for Rotavator Gearbox Using Actual Working Load)

  • 김정길;조승제;이동근;오주영;신민석;박영준
    • 한국기계가공학회지
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    • 제20권6호
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    • pp.92-99
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    • 2021
  • The rotavator is attached to the three-point hitch at the rear of a tractor and uses the power take-off strength of the tractor to perform soil harrowing. During operation, the power transmitted to the gearbox of the rotavator varies with the soil characteristics and depth. These properties influence the reliability of the gearbox. In this study, actual load measurements and analyses were performed using a rotavator. In addition, the safety factor and fatigue life of the gearbox components were determined using the analysis results. Through analysis and tests, the contact pattern of the gear tooth surface was identified. The input power values of the gearbox were minimum and maximum at 54.5% and 84.5% of the tractor power, respectively. Based on the actual load analysis results, the strength and fatigue life of the gearbox components were satisfied. In addition, through the analysis and testing of the gear contact pattern, it was confirmed that a similar contact occurred. Through the analysis, the magnitude of the load acting on the tooth surface of the gear was confirmed.

Changes in the Hydrodynamic Characteristics of Ships During Port Maneuvers

  • Mai, Thi Loan;Vo, Anh Khoa;Jeon, Myungjun;Yoon, Hyeon Kyu
    • 한국해양공학회지
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    • 제36권3호
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    • pp.143-152
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    • 2022
  • To reach a port, a ship must pass through a shallow water zone where seabed effects alter the hydrodynamics acting on the ship. This study examined the maneuvering characteristics of an autonomous surface ship at 3-DOF (Degree of freedom) motion in deep water and shallow water based on the in-port speed of 1.54 m/s. The CFD (Computational fluid dynamics) method was used as a specialized tool in naval hydrodynamics based on the RANS (Reynolds-averaged Navier-Stoke) solver for maneuvering prediction. A virtual captive model test in CFD with various constrained motions, such as static drift, circular motion, and combined circular motion with drift, was performed to determine the hydrodynamic forces and moments of the ship. In addition, a model test was performed in a square tank for a static drift test in deep water to verify the accuracy of the CFD method by comparing the hydrodynamic forces and moments. The results showed changes in hydrodynamic forces and moments in deep and shallow water, with the latter increasing dramatically in very shallow water. The velocity fields demonstrated an increasing change in velocity as water became shallower. The least-squares method was applied to obtain the hydrodynamic coefficients by distinguishing a linear and non-linear model of the hydrodynamic force models. The course stability, maneuverability, and collision avoidance ability were evaluated from the estimated hydrodynamic coefficients. The hydrodynamic characteristics showed that the course stability improved in extremely shallow water. The maneuverability was satisfied with IMO (2002) except for extremely shallow water, and collision avoidance ability was a good performance in deep and shallow water.