• Title/Summary/Keyword: subregion

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Morphologic Alterations in Amygdala Subregions of Adult Patients with Bipolar Disorder

  • Lee, Hyun-Jae;Han, Kyu-Man;Kim, Aram;Kang, Wooyoung;Kang, Youbin;Kang, June;Won, Eunsoo;Tae, Woo-Suk;Ham, Byung-Joo
    • Korean Journal of Biological Psychiatry
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    • v.26 no.1
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    • pp.22-31
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    • 2019
  • Objectives Previous studies have revealed inconsistent results on amygdala volume in adult bipolar disorder (BD) patients compared to healthy controls (HC). Since the amygdala encompasses multiple subregions, the subtle volume changes in each amygdala nucleus might have not been fully reflected in the measure of the total amygdala volume, causing discrepant results. Thus, we aimed to investigate volume changes in each amygdala subregion and their association with subtypes of BD, lithium use and clinical status of BD. Methods Fifty-five BD patients and 55 HC underwent T1-weighted structural magnetic resonance imaging. We analyzed volumes of the whole amygdala and each amygdala subregion, including the anterior amygdaloid area, cortico-amygdaloid transition area, basal, lateral, accessory basal, central, cortical, medial and paralaminar nuclei using the atlas in the FreeSurfer. The volume difference was analyzed using a one-way analysis of covariance with individual volumes as dependent variables, and age, sex, and total intracranial volume as covariates. Results The volumes of whole right amygdala and subregions including basal nucleus, accessory basal nucleus, anterior amygdaloid area, and cortico-amygdaloid transition area in the right amygdala of BD patients were significantly smaller for the HC group. No significant volume difference between bipolar I disorder and bipolar II disorder was found after the Bonferroni correction. The trend of larger volume in medial nucleus with lithium treatment was not significant after the Bonferroni correction. No significant correlation between illness duration and amygdala volume, and insignificant negative correlation were found between right central nucleus volume and depression severity. Conclusions Significant volume decrements of the whole amygdala, basal nucleus, accessory basal nucleus, anterior amygdaloid area, and cortico-amygdaloid transition area were found in the right hemisphere in adult BD patients, compared to HC group. We postulate that such volume changes are associated with altered functional activity and connectivity of amygdala nuclei in BD.

A New Stereo Matching Algorithm (새로운 스테레오 정합 알고리즘)

  • Kim, Choong-Won
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.10 no.10
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    • pp.1829-1834
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    • 2006
  • In this raper in order to recover sharp object boundaries we propose a new efficient stereo matching algorithm in which window size is varied to the distance from the boundaries of object. To this end, the processing region is divided into small subregions with a same area and the disparities of the center pixels in the subregions are calculated using a area-based algorithm with multiple windows. From the this disparity map we can find the edges of the contracted objects. The disparities of original image are obtained using the gradient constraint that means the disparity of the center pixel is similar to the ones of the remaining pixels in the subregion. from the experimental results it is found that the proposed algorithm is very good for recovering sharp object boundaries compared to the similar different algorithm.

An Optimization Algorithm with Novel Flexible Grid: Applications to Parameter Decision in LS-SVM

  • Gao, Weishang;Shao, Cheng;Gao, Qin
    • Journal of Computing Science and Engineering
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    • v.9 no.2
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    • pp.39-50
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    • 2015
  • Genetic algorithm (GA) and particle swarm optimization (PSO) are two excellent approaches to multimodal optimization problems. However, slow convergence or premature convergence readily occurs because of inappropriate and inflexible evolution. In this paper, a novel optimization algorithm with a flexible grid optimization (FGO) is suggested to provide adaptive trade-off between exploration and exploitation according to the specific objective function. Meanwhile, a uniform agents array with adaptive scale is distributed on the gird to speed up the calculation. In addition, a dominance centroid and a fitness center are proposed to efficiently determine the potential guides when the population size varies dynamically. Two types of subregion division strategies are designed to enhance evolutionary diversity and convergence, respectively. By examining the performance on four benchmark functions, FGO is found to be competitive with or even superior to several other popular algorithms in terms of both effectiveness and efficiency, tending to reach the global optimum earlier. Moreover, FGO is evaluated by applying it to a parameter decision in a least squares support vector machine (LS-SVM) to verify its practical competence.

Reproductive Cycle of the Ark Shell, Scapharca subcrenata, on the West Coast of Korea

  • Kwun Sun-Man;Chung Ee-Yung
    • Fisheries and Aquatic Sciences
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    • v.2 no.2
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    • pp.142-148
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    • 1999
  • Monthly changes in the gonad index (GI), egg-diameter composition, gonadal development, reproductive cycle of the ark shell, Scapharca subcrenata, were investigated by histological method and morphometric data. This species is dioecious and oviparous. The gonad is located among the subregion of mid-intestinal gland, digestive diverticula and the outer fibromuscular layers compacted by the fibrous connective tissues and muscle fibers. The gonad index sharply increased in May, reached the maximum value in June, and then gradually decreased from July to December. The reproductive cycle of this species can be divided into six successive stages: early active stage (January to May), late active stage (June to July), ripe stage (June to August), partially spawned stage (July to September), degenerative stage (August to December), and resting stage (January to April). S. subcrenata spawns once a year between July and early September, and the main spawning occurred between July and August when the water temperatures were above $20^{\circ}C$. This evidence suggest that timings of maturation and spawning are closely related to water temperatures. Even though the spawning period was once a year, it is assumed that the number of spawning frequencies (broods) may occur more than twice during the spawning season.

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Analysis of Multi-Layered Structural Systems Using Nonlinear Finite Elements-Boundary Elements (반무한 다중 구조계의 비선형 유한요소 - 경계요소 해석)

  • 김문겸;장정범;이상도;황학주
    • Proceedings of the Computational Structural Engineering Institute Conference
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    • 1992.04a
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    • pp.58-64
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    • 1992
  • It is usual that underground structures are constructed within multi-layered medium. In this paper, an efficient numerical model ling of multi-layered structural systems is studied using coupled analysis of finite elements and boundary elements. The finite elements are applied to the area in which the material nonlinearity is dominated, and the boundary elements are applied to the far field area where the nonlinearity is relatively weak. In the boundary element model 1 ins of the multi-layered medium, fundamental solutions are restricted. Thus, methods which can utilize existing Kelvin and Melan solution are sought for the interior multi-layered domain problem and semi infinite domain problem. Interior domain problem which has piecewise homogeneous layers is analyzed using boundary elements with Kelvin solution; by discretizing each homogeneous subregion and applying compatibility and equilibrium conditions between interfaces. Semi-infinite domain problem is analyzed using boundary elements with Melan solution, by superposing unit stiffness matrices which are obtained for each layer by enemy method. Each methodology is verified by comparing its results which the results from the finite element analysis and it is concluded that coupled analysis using boundary elements and finite elements can be reasonable and efficient if the superposition technique is applied for the multi-layered semi-infinite domain problems.

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The first of its kind metallicity map of the Large Magellanic Cloud

  • Choudhury, Samyaday;Subramaniam, Annapurni;Cole, Andrew A.
    • The Bulletin of The Korean Astronomical Society
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    • v.41 no.2
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    • pp.30.1-30.1
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    • 2016
  • We have estimated a metallicity map of the Large Magellanic Cloud (LMC) using the Magellanic Cloud Photometric Survey (MCPS) and Optical Gravitational Lensing Experiment (OGLE III) photometric data. This is a first of its kind, high-spatial resolution map of metallicity up to a radius of $4^{\circ}-5^{\circ}$, derived using large area photometric data and calibrated using spectroscopic data of Red Giant Branch (RGB) stars. The RGB is identified in the V, (V - I) colour- magnitude diagrams of small subregions of varying sizes in both data sets. The slope of the RGB is used as an indicator of the mean metallicity of a subregion, and it is calibrated to metallicity using spectroscopic data for field and cluster red giants in selected subregions. The mean metallicity of the LMC is found to be [Fe/H] = -0.37 dex (${\sigma}[Fe/H]=0.12$) from MCPS data, and [Fe/H] = -0.39 dex (${\sigma}[Fe/H]=0.10$) from OGLE III data. The bar is found to have an uniform and higher metallicity compared to the disk, and is indicative of an active bar in the past. Both the data sets suggest a shallow radial metallicity gradient up to a radius of 4 kpc ($-0.049{\pm}0.002$ dex kpc-1 to $-0.066{\pm}0.006$ dex kpc-1). This metallicity gradient of the LMC disk, though shallow, resembles the gradient seen in spiral galaxies, and similar to that found in our Galaxy.

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A Study on Sexual Maturation of Mactra veneriformis Reeve (동죽, Mactra veneriformis Reeve 의 성성숙에 관한 연구)

  • Chung, Ee-Yung;Kim, Sung-Yeon;Lee, Taek-Yuil
    • The Korean Journal of Malacology
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    • v.4 no.1
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    • pp.30-41
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    • 1988
  • The gonadal development, the annual reproductive cycle and the first sexual maturity of surf clam, Mactra veneriformis Reeve were studied histologically. Speciemens were monthly collected at the intertidal zone of Naechodo, Chollabuk-do, Korea, for one year from March 1986 to February 1987. Sexuality of the clam is dioecious. The gonads were located between the subregion of mid-intestinal gland in the visceral cavity and the reticular connetive tissues of the foot, The ovary is composed of a number of ovarian sacs, and the testis comprise several testiculat lobules. The undifferentiated mesenchymal tissues and eosinophilic granular cells function as nutritive cells in the early stage. The ripe eggs were about 50-60${\mu}{\textrm}{m}$ in diameter, and they were wurroundedby the gelatinous membranes. The spawing period was from early June to September the main spawning occurred beetween July and August when the water temperature reached above 24$^{\circ}C$. The annual reproductive cycle of this species could be classified into five successive stages: multiplicative(January to March), growing(March to May), mature(April to August), spent(June to September), degenerative and resting(September to February). The monthly changes of fatness coefficient closely correlated with the annual reproductive cycle. Percentages of the first sexual maturity of female and male clams were over 50% among those individals ranging from 2.1 To 2.5cm, and 100% in those over 2.6cm in shell length.

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Shadow Generation By Extracted Point data on Subregion (영역별 데이터 추출에의한 효과적인 그림자 표현)

  • Ko, Chan;Kang, Jung-Ho
    • Journal of the Korea Computer Industry Society
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    • v.3 no.2
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    • pp.217-226
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    • 2002
  • To describe an object realistically is the most important thing in the 3-dimentional space in computer graphics. It is not enough with one or two factors. Several factors should be considered such as perspective sense, cubic effect, material of an object, shadow, strength of light, etc. A shadow algorithm plays an important part in the realistic description of an object. There are many methods to describe a shadow, but it means numerous repeated operations to describe a shadow and it needs much time. We seperate the shadow part and calculate the strength of light for numerous points and it takes much time. This thesis presents a new method to describe a shadow quickly by separating categories maintaining a realistic description of an object.

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Molecular Dynamics Study on the Pattern Transfer in Nanoimprint Lithography (분자 동역학을 이용한 나노임프린트 리소그래피에서의 패턴 전사에 관한 연구)

  • Kang Ji-Hoon;Kim Kwang-Seop;Kim Kyung-Woong
    • Tribology and Lubricants
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    • v.21 no.4
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    • pp.177-184
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    • 2005
  • The molecular dynamics simulation of nanoimprint lithography (NIL) using $SiO_2$ stamp and amorphous poly-(methylmethacrylate) (PNMA) film is performed to study pattern transfer in NIL. Force fields including bond, angle, torsion, van der Waals and electrostatic potential are used to describe the intermolecular and intramolecular force of PMMA molecules and $SiO_2$ stamp. Nose-Hoover thermostat is used to control the system temperature and cell multipole method is adopted to treat long range interactions. The deformation of PMMA film is observed during pattern transfer in the NIL process. For the detail analysis of deformation characteristics, the distributions of density and stress in PMHA film are calculated. The adhesion and friction forces are obtained by dividing the PMMA film into subregions and calculating the interacting force between subregion and stamp. Their effects on the pattern transfer are also discussed as varying the indentation depth and speed.

A Study on Automatic Classification of Fingerprint Images (지문 영상의 자동 분류에 관한 연구)

  • Lim, In-Sic;Sin, Tae-Min;Park, Goo-Man;Lee, Byeong-Rae;Park, Kyu-Tae
    • Proceedings of the KIEE Conference
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    • 1988.07a
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    • pp.628-631
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    • 1988
  • This paper describes a fingerprint classification on the basis of feature points(whorl, core) and feature vector and uses a syntactic approach to identify the shape of flow line around the core. Fingerprint image is divided into 8 by 8 subregions and fingerprint region is separated from background. For each subregion of fingerprint region, the dominant ridge direction is obtained to use the slit window quantized in 8 direction and relaxation is performed to correct ridge direction code. Feature points(whorl, core, delta) are found from the ridge direction code. First classification procedure divides the types of fingerprint into 4 class based on whorl and cores. The shape of flow line around the core is obtained by tracing for the fingerprint which has one core or two core and is represented as string. If the string is acceptable by LR(1) parser, feature vector is obtained from feature points(whorl, core, delta) and the shape of flow line around the core. Feature vector is used hierarchically and linearly to classify fingerprint again. The experiment resulted in 97.3 percentages of sucessful classification for 71 fingerprint impressions.

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