• Molecules and Cells
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• 제38권9호
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• pp.789-795
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• 2015

A chromosome territory is composed of chromosomal subdomains. The internal structure of chromosomal subdomains provides a structural framework for many genomic activities such as replication and DNA repair, and thus is key to determining the basis of their mechanisms. However, the internal structure and regulating proteins of a chromosomal subdomain remains elusive. Previously, we showed that the chromosome territory expanded after BAF53 knockdown. Because the integrity of chromosomal subdomains is a deciding factor of the volume of a chromosome territory, we examined here the effect of BAF53 knockdown on chromosomal subdomains. We found that BAF53 knockdown led to the disintegration of histone H2B-GFP-visualized chromosomal subdomains and BrdU-labeled replication foci. In addition, the size of DNA loops measured by the maximum fluorescent halo technique increased and became irregular after BAF53 knockdown, indicating DNA loops were released from the residual nuclear structure. These data can be accounted for by the model that BAF53 is prerequisite for maintaining the structural integrity of chromosomal subdomains.

• Journal of Electrical Engineering and Technology
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• 제10권4호
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• pp.1674-1681
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• 2015

This paper presented an improved analytical method for calculating armature-reaction field in the surface-mounted permanent magnet machines accounting for opening slots. The analytical model is divided into two types of subdomains. The current of the armature is centralized in the center of the slots. The field solution of each subdomain is obtained by applying the interface and boundary conditions of the model. Two 30-pole/36-slot prototype machines with different slot-opening width are used for validation. The FE (finite element) results confirm the validity of the analytical results with the proposed model. The investigation shows that the wider the slot-opening width is, the smaller the peak value of radial and circumferential components of flux density, and the analytical armature-reaction field produced by centralized current in the slots is similar with the armature-reaction field produced by distributed current in the slots in the FE.

• 한국대기환경학회지
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• 제9권3호
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• pp.242-246
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• 1993

Theoretically, spectral method has the highest accuracy among present numerical methods, but it is generally difficult to apply to complex terrains because of complex boundary conditions. Recently, spectral-element method, basically divide the domain into a set of rectangular subdomain and solve the equation at each subdomain, has been introduced. However, boundary conditions become more complex and requires more computing time, thus spectral-element method is not powerful for all complex terrain problems. In this paper, potential flow theory was intorduced to solve the air flows and diffusion phenomenon in the presence of terrain obstacles. Using the velocity potential-stream line orthogonal coordinate space, the diffusion problems of hilly terrain by pseudospectral method were solved and compared those with no terrain real scale solutions.

• 한국직업건강간호학회지
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• 제22권1호
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• pp.1-12
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• 2013

Purpose: This study aims to test the validity and criteria-related reliability of the Korean version of the Copenhagen Psyco-social Questionnaire version II (COPSOQ-K) assessing the psychosocial working environment. Methods: The COPSOQ-K was developed through forward-backward translation techniques, and revision based on feedback from focus groups. Survey data were collected from 311 office workers who worked in one workplace. An internal consistency reliability was estimated by Cronbach's ${\alpha}$. The impacts of the COPSOQ-K scales on job satisfaction, self-rated health, stress, sleeping troubles, burnout, and sickness absence were analyzed with multiple regression model or multiple logistic regression model, adjusted age and gender using SAS version 9.3. The Pearson correlation coefficients between the COPSOQ-K scales and Korean job stress and its subdomain were identified. Results: Cronbach's ${\alpha}$ of COPSOQ-K scales was adequate or good (0.66~0.87). The major COPSOQ-K scales predict job satisfaction, self-rated health, stress, sleeping troubles burnout, and sickness absence. The major COPSOQ-K scales were correlated with Korean job stress and its subdomain. Conclusion: The COPSOQ-K scales have satisfactory reliability and criteria-related validity. The COPSOQ-K scales will be useful for the future studies and practices associated with psychosocial working environment.

• 한국정밀공학회지
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• 제23권11호
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• pp.93-102
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• 2006

In this study an advanced domain decomposition method is suggested in order to construct surface models from very large amount of points. In this method the spatial domain of interest that is occupied by the input set of points is divided in repetitive manner. First, the space is divided into smaller domains where the problem can be solved independently. Then each subdomain is again divided into much smaller domains where the problem can be solved locally. These local solutions of subdivided domains are blended together to obtain a solution of each subdomain using partition of unity function. Then the solutions of subdomains are merged together in order to construct whole surface model. The suggested methods are conceptually very simple and easy to implement. Since RDDM(Repetitive Domain Decomposition Method) is effective in the computation time and memory consumption, the present study is capable of providing a fast and accurate reconstructions of complex shapes from large amount of point data containing millions of points. The effectiveness and validity of the suggested methods are demonstrated by performing numerical experiments for the various types of point data.

• 보건의료산업학회지
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• 제13권3호
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• pp.53-65
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• 2019

Objectives: This descriptive survey study aimed to identify factors that affect job satisfaction among nurses working in integrated nursing care service wards and to explore measures to increase job satisfaction among these nurses. Methods: Data were collected between July 20 and August 3, 2018 from nurses working in integrated nursing care service wards in Busan and Changwon city, in Korea. Data were analyzed with SPSS/WIN 23.0 software(IBM corp., Armonk, NY, USA). Results: Factors affecting job satisfaction among nurses working in integrated nursing care service wards were identified as follows: professional self-concept (${\beta}=.32$, p=.003), which is a subdomain of nursing professionalism, and nursing foundations for quality care (${\beta}=.30$, p=.001), which is a subdomain of nursing work environment. The model had an explanatory power of 54.7%. Conclusions: Nursing professionalism should be strongly established among nurses, as nurses are key players in a health system that allows stable and expanded operations of integrated nursing care. Intervention measures that create a better work environment for nurses should also be implemented. Furthermore, it is necessary to develop systematic strategies and multifaceted efforts to increase nurses' job satisfaction in integrated nursing care service wards.

• 한국전산유체공학회:학술대회논문집
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• 한국전산유체공학회 1997년도 추계 학술대회논문집
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• pp.23-28
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• 1997

A parallel implementation is made of a two-dimensional finite volume model based on the SIMPLER. The solution domain is decomposed into several subdomains and the solution at each subdomain is acquired by parallel use of multiple processors. Communications between processors are accomplished by using the standard MPI and the Cray-specific SHMEM. The parallelization method for the overall solution procedure to the Navier-Stokes equations is described in detail, The parallel implementation is validated on the Cray T3E system for a benchmark problem of natural convection in a sidewall-heated cavity. The parallel performance is assessed and the issues encountered in achieving a high-performance parallel model are elaborated.

• 대한조선학회지
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• 제19권4호
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• pp.19-29
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• 1982

Galerkin's finite element method is applied to a two-dimensional heat convection-diffusion problem arising in the hydrodynamic lubrication of thrust bearings used in naval vessels. A parabolized thermal energy equation for the lubricant, and thermal diffusion equations for both bearing pad and the collar are treated together, with proper juncture conditions on the interface boundaries. it has been known that a numerical instability arises when the classical Galerkin's method, which is equivalent to a centered difference approximation, is applied to a parabolic-type partial differential equation. Probably the simplest remedy for this instability is to use a one-sided finite difference formula for the first derivative term in the finite difference method. However, in the present coupled heat convection-diffusion problem in which the governing equation is parabolized in a subdomain(Lubricant), uniformly stable numerical solutions for a wide range of the Peclet number are obtained in the numerical test based on Galerkin's classical finite element method. In the present numerical convergence errors in several error norms are presented in the first model problem. Additional numerical results for a more realistic bearing lubrication problem are presented for a second numerical model.

• 한국통신학회논문지
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• 제26권8A호
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• pp.1378-1387
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• 2001

인터넷 서비스의 다양화와 네트워크의 대형화로 인하여 서브 도메인(Subdomain) 및 도메인을 포함한 인터넷 전체에 걸쳐 적용할 수 있는 계층적 구조의 보안 모델의 정의와 이 모델을 기반으로 하는 보안 정책 프로토콜의 표준화가 요구되고 있다. 이 논문에서는 기존 보안 정책 서버 구조를 기존의 Internet-Draft 문서를 통해 분석하고 그것을 바탕으로 계층적 보안 정책 구조를 제시한 후 보안 정책 연동 프로토콜을 설계한다. 이를 위해 보안정책 프로토콜을 확장하고 그룹개념을 위한 질의와 레코드를 확장 설계하고 계층적 보안 모델에서 효과적인 보안정책 상속 및 수정을 위한 갱신 레코드를 정의한다. 또한 동일한 정책 속성을 갖는 호스트들의 모임을 그룹으로 정의하고, 이 개념을 기반으로 효율적인 연동 메커니즘을 설계한다.

• 전산구조공학
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• 제8권3호
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• pp.75-78
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• 1995

이 논문에서는 경계요소법을 사용하여 서로 다른 탄성체들이 무한하게 적층된 복합구조체의 자유경계면에서 발생하는 특이 응력을 조사하였다. 종속영역법을 도입하여, 해석모델을 독립된 탄성영역들로 나누었고, 해석모델의 공유경계면에 변위연속조건과 표면력 평형조건을 적용하여 경계요소공식을 유도하였다. 예제의 문제에 대한 수치해석 결과를 제시하였다.