Recently, portion of the aged population has been increased, and aging became the biggest issue that we will be facing in the future. As the aging population has increased, the silver generation is getting to account for the considerable percent of economic activities and becomes the main body of production and consumption. Although the economic activity of silver generation is increased, the development of silver contents for the leisure activities is still not revitalized. The serious silver contents and the easy-to-use interface are very important because the silver generation is relatively weaker than young people in perception, studying, and exercise, and is fragile in mobility and vitality. This paper suggests the Sensory 3D Gate-Ball game for silver generation's leisure and health maintaining along with the easy-to-use interface.
BACKGROUND/OBJECTIVES: Recent living condition improvements, changes in dietary habits, and reductions in physical activity are contributing to an increase in metabolic syndrome symptoms including diabetes and obesity. Through such societal developments, humankind is continuously exposed to metabolic diseases such as diabetes, and the number of the victims is increasing. This study investigated Cordyceps militaris water extract (CMW)-induced glucose uptake in HepG2 cells and the effect of CMW treatment on glucose metabolism. MATERIALS/METHODS: Colorimetric assay kits were used to determine the glucokinase (GK) and pyruvate dehydrogenase (PDH) activities, glucose uptake, and glycogen content. Either RT-PCR or western blot analysis was performed for quantitation of glucose transporter 2 (GLUT2), hepatocyte nuclear factor 1 alpha ($HNF-1{\alpha}$), phosphatidylinositol 3-kinase (PI3k), protein kinase B (Akt), phosphorylated AMP-activated protein kinase (pAMPK), phosphoenolpyruvate carboxykinase, GK, PDH, and glycogen synthase kinase 3 beta ($GSK-3{\beta}$) expression levels. The ${\alpha}-glucosidase$ inhibitory activities of acarbose and CMW were evaluated by absorbance measurement. RESULTS: CMW induced glucose uptake in HepG2 cells by increasing GLUT2 through $HNF-1{\alpha}$ expression stimulation. Glucose in the cells increased the CMW-induced phosphorylation of AMPK. In turn, glycolysis was stimulated, and glyconeogenesis was inhibited. Furthermore, by studying the mechanism of action of PI3k, Akt, and $GSK-3{\beta}$, and measuring glycogen content, the study confirmed that the glucose was stored in the liver as glycogen. Finally, CMW resulted in a higher level of ${\alpha}-glucosidase$ inhibitory activity than that from acarbose. CONCLUSION: CMW induced the uptake of glucose into HepG2 cells, as well, it induced metabolism of the absorbed glucose. It is concluded that CMW is a candidate or potential use in diabetes prevention and treatment.
Journal of the Korean Society for Precision Engineering
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v.26
no.7
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pp.134-141
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2009
Recently, many researchers have tried to develop wearable robots for various fields such as medical and military purposes. We have been studying robotic exoskeletons to assist the motion of persons who have problems with their muscle function in daily activities and rehabilitation. The upper-limb motions (shoulder, elbow and wrist motion) are especially important for such persons to perform daily activities. Generally for shoulder motion 300F is needed to describe its motion(extension/flexion, abduction/adduction, internal/external rotation) but we have used a redundant actuator thus making a 4 DOF system. In this paper, we proposed the mechanism design of the exoskeleton which consists of 4-DOF for shoulder and 1-DOF for elbow robotic exoskeleton to assist upper-limb motion. Then we compared the new mechanism design and prototype mechanism design. Here we also analyze the proposed system kinematically to find out and to avoid the singular point. This research will ensure that the proposed wearable robot system make human's motion more powerfully and more easily.
The physical environment can dramatically affect students' feeling and their behavior, educational attainment, and the way in which we do school activities. Unlimited access to campus areas without appropriate securities have reported an increase of crime in school area and safety issues has encouraged school facility planners to install securities devices at every corner of buildings. However, it is still questionable whether this approach is enough to protect students and staffs from the victimization of crime, including thefts, burglaries and sexual offences. There has been continued doubt about the safety of educational facilities where individual college students are studying and enjoying extra-curricular activities. Therefore, the purpose of this study is intended to investigate the effects of perception of safety by students on the level of academic performance at public outdoor environment of university campus. An extensive literature noted that the central element of modern school design principle mainly holds the theory of crime prevention through environmental design (CPTED) and the concept of defensible space. The second generation of CPTED also focused on social soft issues as well as situational factors, which extends beyond mere physical design to include social factors. The correlation analysis found that the effect of sense of safety does appear to be statistically significant on the facilitation of academic achievement. However, the analysis of Chi-square concluded that the perception of safety was not related to demographic and socio-economic profiles of the group except for gender. Further, stepwise multiple regression analysis revealed that the most prime predictor for academic achievement were 'safe public outdoor space/paths' at university campus environment, implying careful design of public open space and sidewalks based on the guideline of CPTED. The study also demonstrated that as the level of positive perception of safety rose, the overall academic achievement also responded to the specified rate (${\beta}=.99$). Finally, the findings reinforce an evidence that high-quality school environments are a positive factor in student academic performance.
This study was concentrated on the development of the effective noise environmental education program(NEEP) for elementary student. And through this program, the student who is remaining as a spector or has not active attitude for noise problems will be encouraged to solve the troubles spontaneously. The object of this study was the two classes in H elementary school where is near to the Daegu international airport. One class that is a group for experiment has five NEEP lessons during five weeks in the time for the creative discretional activities. The other class, which was compared with the experimental group was given no lessons. NEEP was made on the bases that are the contents related with noise in 7th elementary education policy and the data developed by previous researchers. This program is containing basic concepts for noise and the effects of noise problems on human body or studying in class. And after using NEEP, students became more sensitive for noise environments than previous. And also students showed the positive attitude for solving noise troubles. It was meaningful in the level of p<.001 that the result of noise knowledge and awareness in the pre-post test within experiment group. However, all of the results in comparison group didn't represent statistically meaningful difference. And there were meaningful differences between experiment and comparison group after carrying out NEEP. In the area of noise knowledge and awareness, there were clearly meaningful results in the level of p<.001. Although the difference in noise attitude was a little, it was analyzed to have not a meaningful result. What suggested for researches in future are as follows. First, because until now the concrete research for the elementary student who exposed to noise and experienced a difficulty in hearing is deficient, many studies are needed. Second, NEEP with more lessons is required because the change of effective attitude needs long term. Third, due to the student who exposed to noise generally has low ability for concentration, NEEP compensated with activities is needed.
It is well known that vital statistics is of great importance as basic data for establishing various range of national policies. Especially, vital statistics is important among demographic information for monitoring and evaluating the population policy, for constructing life table, for making population projection, and for studying various aspects of the society. In principle, the production of vital statistics is based on the registration system. It is, however, still observed that there are some limitations in utilizing fully the registration system due to the inherent problems such as problems in its coverage, accuracies and timeliness. Thus, as an alternative, many countries conduct survey on vital statistics in order to supplement the registration system and obtain in-depth data. Korea is no exception in this aspect. The National Bureau of Statistics carries out the so-called Continuous Demographic Survey. This is a kind of multi-round retrospective survey, covering 32, 000 households and having reference period of one month. The survey has also characteristics of multi-subject sample. Thus, surveys on economic activity status of population, house-hold income & expenditure, and social indicators are together conducted with the same sample. It is, however, found that the survey itself tends to have some quality problems. Especially, the quality problems connected with field data collection are summarized as coverage error, non-response error and response error. Although it is inevitable not to be free from these errors, we should make all our efforts to reduce the errors. The probable schemes pointed out in this paper are as follows : 1) the strengthening formal quality control activities, 2) the review of the survey method, i. e., the combining interview method with mail-sending and mail-back method or pick-up method, 3) well documentation for various cases found in every stage of data collection, and 4) the strengthening the analytical activities. It is, also, emphasized that sincerity of planners and interviewers is the most important factor among other things.
Journal of Information Technology Applications and Management
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v.25
no.1
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pp.1-17
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2018
This study presents a research model that demonstrates the dominant design technology strategy for developing and securing dominant design technology based on open innovation. For this purpose, this study developed a strategic model for the development and acquisition of design technology, production technology, and production system of propeller which satisfies the requirements of ship propulsion system required by ship owners and shipbuilders. By studying large propellers for ships, it is possible to embody a strategic model that can be used as a technology development strategy of dominant design that is effective in technology field of other industries. In this study, HSP (High Skewed Propeller) strategy of Hyundai Heavy Industries, which occupies the largest global market share (47.5%, 2007) for more than 30 years until now, is analyzed as a successful case to verify this strategic model. The development and acquisition strategy model of dominant design technology presented in this study consists of four stages : dominant design project strategy, dominant design engineering technology strategy, dominant design production technology strategy, and dominant design production system strategy. The strategic model summarizes the key activities at each stage. In addition, the steps and core activities of this strategic model were confirmed through the case study. As a technology development strategy of HSP products, Hyundai Heavy Industries utilized open innovation technology to cooperate with outside, that is, collaborative research and development with KAIST (Korea Advanced Institute of Science and Technology) research team, and succeeded in achieving technology development of dominant design of HSP products by linking it with HSP technology development and acquisition strategy.
With the appearance of the Internet and the development of the World Wide Web, web-based education has made individual and selective learning centered on students in cyberspace available at any time and anywhere. In this paper, we design and implement courseware for a web-based 4th-year elementary school mathematics course. In order to make it as student-centered as possible, the courseware adopted learning activities using various Flash animation and design methodology to enhance students' interest to complete all parts of the course. When we gave our WBI courseware to 4th-year elementary school students to use, their achievement in the subject was greater than a group who studied with the traditional course. The results of the question investigation of the experimental group showed a positive reaction and increased educational achievements in the fields of comprehension, interest, convenience and reflection on self-directed learning.
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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v.30
no.2
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pp.100-111
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2017
Objectives : The purpose of this study was to research the antibiotic, antioxidant and whitening effects of Jwa Kum-Whan(JKW) and Soo Ryeon-Whan(SRW). Both Jwa Kum-Whan and Soo Ryeon-Whan are composed of Coptidis rhizoma and Evodiae fructus, but the ratios of the two species are different. JKW is composed of Coptidis rhizoma and Evodiae fructus by ratio of 6:1 and SRW's ratio is 1:1. Methods : Antibiotic activities of JKW and SRW's water extracts were studied by paper disc diffusion method. Four kinds of bacteria were applied in paper disc, and each extract was dropped, individually. The diameter of inhibition zone was measured. DPPH assay was used for studying free radical scavenging activity. DPPH is quantitatively decolorized from purple color by antioxidant material. Change of color was measured by spectrophotometer. Whitening activity was analyzed by tyrosinase inhibition assay. Tyrosinase is major enzyme for control process of making eumelanin. Optical Density was measured by spectrophotometer. Results : Candida albicans and Staphylococcus aureus's inhibition zone were made large available by Both prescriptions. Inhibition zone's diameter of JKW was preferable to SRW's. Radical scavenging activity was better at SRW, but JKW's activity was available, too. Tyrosinase inhibition activity was found out available only for JKW, not for SRW. Conclusions : JKW had antibiotic effects for Candida albicans, Staphylococcus aureus. And had antioxidant, whitening effects. SRW had antibiotic, antioxidant activities but not whitening effect.
Journal of the Korea Society of Computer and Information
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v.5
no.4
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pp.7-12
/
2000
This paper is an attempt to design and implement a multimedia title for the lesson of' Creatu Environment' which appears in the textbook of the second semester for the fourth graders. The title make the most use do multimedia features so that students my be able to reach the best result of activities. The title adopts the Cocktail program developed by Hite-Media Co. It is designed to resolve that are associated with sequential and letter-centered simplicity. As a result, students can interact on the other and the amount of their lessons. The title can effectively combines visual and aural (i. e. information to bring in motivations and participations in learning activities. This title is believed to help students to solve many classroom questions and to try individual learning. Finally, it is hoped that the title helps students to understand the ultimate go subject. 'Environment does affect the life of plants'.
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