• Title/Summary/Keyword: stress mechanism

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Study on Intestinal Flora and IgA Concentration Analysis in Newborn Mice by Stress and Diet in Pregnant Mice to Investigate the Effect of Taedok on the Intestinal Flora (태독이 장내 세균총에 미치는 영향을 규명하기 위한 임신쥐의 스트레스 및 식이에 따른 신생쥐의 장내 세균총 및 IgA 농도 분석 시험)

  • Jeong, Jieun;Choi, Yoomin;Jeong, Minjeong
    • The Journal of Pediatrics of Korean Medicine
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    • v.35 no.4
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    • pp.96-111
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    • 2021
  • Objectives The purpose of this study is to look for pathological mechanism of disease development caused by Taedok, by studying whether stress and diet in pregnant ICR mice affect the intestinal flora and IgA (Immunoglobulin A) concentration. Methods The mice were divided into 4 groups (n=5 per group) based on the concept of Taedok: the control group (G1), stress group (G2), capsaicin diet group (G3), high fat diet group (G4). We collected and analyzed intestinal flora from maternal feces and cecal flora from neonatal mice by group. Then, IgA concentration in the maternal feces and sIgA (secretory Immunoglobulin A) concentration in the cecal contents of newborn mice were analyzed. In addition, serum corticosterone was analyzed before and after stress application. Results Changes in maternal intestinal flora and neonatal mice cecal flora by stress and diet were observed. There were no significant changes in the IgA concentration in maternal feces and the sIgA concentration in the cecal contents of neonatal mice. No significant changes compared to the control group were observed between groups before and after applying stress. However, when comparing within one subject, a significant increase was confirmed after stress application in the stress group (G2). Conclusions Based on the results, we observed stress and diet in pregnant mice affect the intestinal flora of maternal and neonatal. We were able to interpret the pathological mechanism of Taedok based on the principle of interaction between mother and newborn intestinal flora.

Effect of an temperatures of post-spray heat treatment on wear behavior of $8%Y_2O_3-ZrO_2$ coating

  • Chae, Y.H.;Kim, S.S.
    • Proceedings of the Korean Society of Tribologists and Lubrication Engineers Conference
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    • 2002.10b
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    • pp.181-182
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    • 2002
  • Most recent, Plasma ceramic spray is used on parts of tribosystem, has been investigated on the tribological performance. The application of ceramic coatings by plasma spray has become essential in tribosystems to produce better wear resistance and longer life in various conditions. The purpose of this work was to investigate the wear behavior of $8%Y_2O_3-ZrO_2$ coating due to temperatures of post-spay heat treatment. The plasma-sprayed $8%Y_2O_3--Zirconia$ coating was idiscussed to know the relationship between phase transformations and temperatures of post- spray heat treatment. Wear tests was carried out with ball on disk type on normal load of 50N, 70N and 90N under room temperature. The transformation of phase and the value of residual stress were measured by X-ray diffraction method(XRD). Tribological characteristics and wear mechanisms of coatings was observed by SEM. The tribologieal wear performance was discussed a point of view for residual stress. Consequently. post-spray heat treatment plays an important role in decreasing residual stress. Residual stress in coating system has a significant influence on the wear mechanism of coating.

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Characterization of the brittleness of hard rock at different temperatures using uniaxial compression tests

  • Chen, Guoqing;Li, Tianbin;Wang, Wei;Guo, Fan;Yin, Hongyu
    • Geomechanics and Engineering
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    • v.13 no.1
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    • pp.63-77
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    • 2017
  • The failure mechanism of a deep hard rock tunnel under high geostress and high geothermalactivity is extremely complex. Uniaxial compression tests of granite at different temperatures were conducted. The complete stress-strain curves, mechanical parameters and macroscopic failure types of the rock were analyzed in detail. The brittleness index, which represents the possibility of a severe brittleness hazard, is proposed in this paperby comparing the peak stress and the expansion stress. The results show that the temperature range from 20 to $60^{\circ}C$ is able to aggravate the brittle failure of hard rock based on the brittleness index. The closure of internal micro cracks by thermal stress can improve the strength of hard rock and the storage capacity of elastic strain energy. The failure mode ofthe samples changes from shear failure to tensile failure as the temperature increases. In conclusion, the brittle failure mechanism of hard rock under the action of thermal coupling is revealed, and the analysis result offers significant guidance for deep buried tunnels at high temperatures and under high geostress.

Platform of Hot Pepper Stress Genomics: Indentification of Stress Inducible Genes in Hot Pepper (Capsicum annuum L.) Using cDNA Microarray Analysis

  • Chung, Eun-Jo;Lee, Sanghyeob;Park, Doil
    • Proceedings of the Korean Society of Plant Pathology Conference
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    • 2003.10a
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    • pp.81.1-81
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    • 2003
  • Although plants have evolved to possess various defense mechanisms from local biotic and abiotic stressors, most of yield loss is caused by theses stressors. Recent studies have revealed that several different stress responsive reactions are inter-networking. Therefore, the identification and dissection of stress responsive genes is an essential and first step towards understanding of the global defense mechanism in response to various stressors. For this purpose, we applied cDNA microarray analysis, because it has powerful ability to monitor the global gene expression in a specific situation. To date, more than 10,000 non-redundant genes were identified from seven different cDNA libraries and deposited in our EST database (http://plant.pdrs.re.kr/ks200201/pepper.html). For this study, we have built 5K cDNA microarray containing 4,685 unigene clones from three different cDNA libraries. Monitoring of gene expression profiles of hot pepper interactions with biotic stress, abiotic stresses and chemical treatments will be presented. Although this work shows expression profiling at the sub-genomic level, this could be a good starting point to understand the complexity of global defense mechanism in hot pepper.

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Analysis of Deep-Trap States in GaN/InGaN Ultraviolet Light-Emitting Diodes after Electrical Stress

  • Jeong, Seonghoon;Kim, Hyunsoo;Lee, Sung-Nam
    • Journal of the Korean Physical Society
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    • v.73 no.12
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    • pp.1879-1883
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    • 2018
  • We analyzed the deep-trap states of GaN/InGaN ultraviolet light-emitting diodes (UV LEDs) before and after electrical stress. After electrical stress, the light output power dropped by 5.5%, and the forward leakage current was increased. The optical degradation mechanism could be explained based on the space-charge-limited conduction (SCLC) theory. Specifically, for the reference UV LED (before stress), two sets of deep-level states which were located 0.26 and 0.52 eV below the conduction band edge were present, one with a density of $2.41{\times}10^{16}$ and the other with a density of $3.91{\times}10^{16}cm^{-3}$. However, after maximum electrical stress, three sets of deep-level states, with respective densities of $1.82{\times}10^{16}$, $2.32{\times}10^{16}cm^{-3}$, $5.31{\times}10^{16}cm^{-3}$ were found to locate at 0.21, 0.24, and 0.50 eV below the conduction band. This finding shows that the SCLC theory is useful for understanding the degradation mechanism associated with defect generation in UV LEDs.

Fracture and Protection Technologies against Impulse of Power Arresters (전력용 피뢰기의 임펄스에 의한 파손과 대척 기술)

  • 한세원;조한구;김석수
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2001.07a
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    • pp.190-193
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    • 2001
  • ZnO varistors have been widely used to protect power system and electronic system against overvoltages based on their excellent nonlinearity. In order to increase their protection capability, the fracture and protection technologies of arresters have to study according to their applications, namely ImA DC voltage, leakage currents, impulse residual voltages, withstanding capability to impulse surge, and energy absorption capability. ZnO varistors which have nonlinear current-voltage characteristic name a number of failure mechanism when ZnO elements absorb surge energies. Failure mode by thermal stress and Pin hole are among the most common failure mechanism at the high current surge current. In this study, the fracture mechaism of power arresters are introduced and protection technologies are researched. In particular the effect of thermal stress by surge currents to ZnO elements and methods against arc surge energy through withstand structure design of arrester are discussed.

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Design of Accelerated Test for Reliability Assurance of SHAFT Assembly (SHAFT 어셈블리 신뢰성 보증을 위한 가속시험의 설계)

  • 김준홍;오근태;김명수
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.23 no.61
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    • pp.75-87
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    • 2000
  • This paper proposes a procedure for designing an accelerated test using SMAT(Stress, (failure) Mechanism and Test) model describing the relation among stress, failure mode/mechanism and test method. In SMAT model the stresses to be applied are derived from the environmental factor analysis, the relative importance of those stresses can be estimated using AHP(Analytic Hierarchy Process) and failure mode/mechanism and test method are derived from the fields failure information and FMEA(Failure Mode and Effect Analysis). By applying the procedure we can make a selection of major factors to cause the failure of assembly and design the accelerated test using DOE(Design of Experiments) The procedure is illustrated with an qualification test case study of washing machine shaft assembly in "A" electric appliance company.

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Improvement of Fatigue-Proof Characteristics of Link Members Under Impact Loadings by a Spring-Actuated Mechanism (스프링구동 메커니즘의 충격 하중을 받는 링크부재의 내피로 특성 향상)

  • 안길영;박상후;이부윤;김원진;오일성
    • Journal of the Korean Society for Precision Engineering
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    • v.20 no.4
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    • pp.158-164
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    • 2003
  • The air circuit breaker (ACB) with the spring-actuated mechanism was studied to improve the fatigue-proof characteristics of its link. The low-cycle fatigue fracture phenomenon occurred on the critical link, called h-link, of ACB from the repeated rapid closing and opening operations. To analyze the cause of failure, dynamic FE-analysis on the b-link part of ACB was performed considering tile velocity and acceleration of the links per time as boundary conditions, which were obtained by using ADAMS. Also, the S-N curve obtained by experiments was used to investigate requirement on the fatigue-proof characteristics. Then, to reduce the maximum tensile stress on the h-link, three types of h-link were examined and one of them was selected.

The Interpretation of Separation Mechanism of Ridge-Cut Explosive Bolt Using Software Simulation Program

  • Lee, Y. J.;Kim, D. J.
    • Proceedings of the Korean Society of Propulsion Engineers Conference
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    • 2004.03a
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    • pp.532-543
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    • 2004
  • The present work have been developed the interpretation processor including the behavior of material failure and the separation phenomena under transient dynamic loading (the operation of explosive bolt) using AUTODYN V4.3, SoildWork 2003 and TrueGrid V2.1 programs. It has been demonstrated that the interpretation in ridge-cut explosive bolt under dynamic loading condition should be necessary to the appropriate failure model and the basic stress of bolt failure is the principal stress. The use of this interpretation processor developing the present work could be extensively helped to design the shape and the amount of explosives in the explosive bolt having a complex geometry. It is also proved that the interpretation processor approach is an accurate and effective analysis technique to evaluate the separation mechanism in explosive bolts.

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The moderating role of motivations in problematic use of online gaming: A study of live streaming viewers of Twitch

  • Chen, Chi-Ying;Chang, Shao-Liang
    • International Journal of Internet, Broadcasting and Communication
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    • v.11 no.2
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    • pp.84-92
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    • 2019
  • While the Internet continues to integrate with modern lives, the risks of negative outcomes resulting from problematic use (PU) are also increasing. Although psychological well-being and use motivations have been shown to play major roles in Internet PU, understanding the moderating mechanism is critical for advanced knowledge. The present study employed survey data from users of a live video-game streaming service (LVGS) that is an area rarely been studied. Result concluded a positive moderating effect of escapism motive (EM) on the association between loneliness and the PU of LVGS, while the moderating mechanism between EM and stress was not indicated. A moderating effect of information seeking (IS) on the relationship between stress and the PU of LVGS was found negative, but no mechanism between IS and loneliness was indicated. This study highlights how the interplay of different motivation and pathologies may induce or prevent video-game-related addiction.