• Title/Summary/Keyword: stress intensity factor

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Marine phytoplankton improves recovery and sustains immune function in humans and lowers proinflammatory immunoregulatory cytokines in a rat model

  • Sharp, Matthew;Wilson, Jacob;Stefan, Matthew;Gheith, Raad;Lowery, Ryan;Ottinger, Charlie;Reber, Dallen;Orhan, Cemal;Sahin, Nurhan;Tuzcu, Mehmet;Durkee, Shane;Saiyed, Zainulabedin;Sahin, Kazim
    • Korean Journal of Exercise Nutrition
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    • v.25 no.1
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    • pp.42-55
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    • 2021
  • [Purpose] This study investigated the effects of marine phytoplankton supplementation (Oceanix®, Tetraselmis chuii) on 1) maximal isometric strength and immune function in healthy humans following a oneweek high-intensity resistance-training program and 2) the proinflammatory cytokine response to exercise in a rat model. [Methods] In the human trial, 22 healthy male and female participants were randomly divided into marine phytoplankton and placebo groups. Following baseline testing, participants underwent a 14-day supplement loading phase before completing five consecutive days of intense resistance training. In the rat model, rats were randomly divided into four groups (n=7 per condition): (i) control, (ii) exercise, (iii) exercise + marine phytoplankton (2.55 mg/kg/day), or (iv) exercise + marine phytoplankton (5.1 mg/kg/day). Rats in the exercising groups performed treadmill exercise 5 days per week for 6 weeks. [Results] In the human model, marine phytoplankton prevented significant declines in the isometric peak rate of force development compared to placebo. Additionally, salivary immunoglobulin A concentration was significantly lower following the resistance training protocol in the placebo group but not in the marine phytoplankton group. Marine phytoplankton in exercising rats decreased intramuscular levels and serum concentrations of tumor necrosis factor-alpha (TNF-α) and interleukin-1 beta (IL-1β) and intramuscular concentrations of malondialdehyde. [Conclusion] Marine phytoplankton prevented decrements in indices of functional exercise recovery and immune function. Mechanistically, these outcomes could be prompted by modulating the oxidative stress and proinflammatory cytokine response to exercise.

Aluminum toxicity-induced alterations of root proteome in wheat seedlings

  • Oh, Myeong Won;Roy, Swapan Kumar;Cho, Kun;Cho, Seong-Woo;Park, Chul-Soo;Chung, Keun-Yook;Choi, Jong-Soon;Woo, Sun-Hee
    • Proceedings of the Korean Society of Crop Science Conference
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    • 2017.06a
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    • pp.127-127
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    • 2017
  • Aluminum is the most abundant metallic element in the Earth's crust and considered as the most limiting factor for plant productivity in acidic soils. The inhibition of root growth is recognized as the primary effect of Al toxicity. Seeds of wheat cv. Keumkang (Korean cultivar) were germinated on petridish for 5 days and then transferred hydroponic apparatus which was treated with $0{\mu}M$ $AlCl_3$ (control), $100{\mu}M$ $AlCl_3$ and $150{\mu}M$ $AlCl_3$ for 5 days. The length of roots, shoots and fresh weight of wheat seedlings were decreased under aluminum stress. The concentrations of $K^+$, $Mg^{2+}$ and $Ac^{2+}$ were decreased whereas $Al^{3+}$ and $P_2O_5{^-}$ concentration was increased under aluminum stress. Using confocal microscopy, the fluorescence intensity of aluminum was increased with morin staining. In this study, a proteome analysis was performed to identify proteins, which is responsible to aluminum stress in wheat roots. In 10-day-old seedlings, proteins were extracted from roots and separated by 2-DE, stained by CBB. Using image analysis, a total of 47 differentially expressed protein spots were selected, whereas 19 protein spots were significantly up-regulated such as s-adenosylmethionine, oxalate oxidase, malate dehydrogenase, cysteine synthase, ascorbate peroxidase and 28 protein spots were significantly down-regulated such as heat shock protein 70, o-methytransferase 4, enolase, amylogenin by aluminum stress following protein spots analyzed by LTQ-FTICR mass spectrometry. The results provide the global picture of Al toxicity-induced alterations of protein profiles in wheat roots, and identify the Al toxicity-responsive proteins related to various biological processes that may provide some novel clues about plant Al tolerance.

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Electromagnetic Interference Shielding Effectiveness and Mechanical Properties of MWCNT-reinforced Polypropylene Nanocomposites (다중벽 탄소나노튜브강화 폴리프로필렌 나노복합재료의 전자파 차폐효과 및 기계적 특성)

  • Yim, Yoon-Ji;Seo, Min-Kang;Kim, Hak-Yong;Park, Soo-Jin
    • Polymer(Korea)
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    • v.36 no.4
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    • pp.494-499
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    • 2012
  • In this work, the effect of multi-walled carbon nanotube (MWCNT) on electromagnetic interference shielding effectiveness (EMI SE) and mechanical properties of MWCNT-reinforced polypropylene (PP) nanocomposites were investigated with varying MWCNT content from 1 to 10 wt%. Electric resistance was tested using a 4-point-probe electric resistivity tester. The EMI SE of the nanocomposites was evaluated by means of the reflection and adsorption methods. The mechanical properties of the nanocomposites were studied through the critical stress intensity factor ($K_{IC}$) measurement. The morphologies were observed by scanning electron microscopy (SEM). From the results, it was found that the EMI SE was enhanced with increasing MWCNT content, which played a key factor to determine the EMI SE. The $K_{IC}$ value was increased with increasing MWCNT content, whereas the value decreased above 5 wt% MWCNT content. This was probably considered that the MWCNT entangled with each other in PP due to an excess of MWCNT.

A Study on Thermal Conductivity and Fracture Toughness of Alumina Nanofibers and Powders-filled Epoxy Matrix Composites (알루미나 나노섬유와 분말이 첨가된 에폭시 복합재료의 열전도도 특성 및 파괴인성에 대한 연구)

  • Choi, Jeong-Ran;Park, Soo-Jin
    • Polymer(Korea)
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    • v.37 no.1
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    • pp.47-51
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    • 2013
  • In this work, the effect of alumina nanofibers on thermal conductivity and fracture toughness of alumina nanofibers and powder filled epoxy (EP) composites were investigated with varying alumina nanofiber content from 20 to 100 phr. Thermal conductivity was tested using a laser flash analysis (LFA). The fracture toughness of the composites were studied through the critical stress intensity factor ($K_{IC}$) measurement. The mophologies were observed by scanning electron microscopy (SEM). From the results, it was found that the thermal conductivity was enhanced with increasing alumina nanofiber content, which played a key factor to determine the thermal conductivity. The $K_{IC}$ value was increased with increasing alumina nanofiber content, whereas the value decreased above 40 phr alumina nanofiber content. This was probably considered that the alumina nanofiber entangled each other in EP due to an excess of alumina nanofibers.

A study on the application of optical fiber sensors to smart composite structures (지능형 복합재 구조물에 대한 광섬유센서의 적용에 관한 연구)

  • Jang, Tae-Seong;Kim, Ho;Lee, Jung-Ju
    • Journal of Sensor Science and Technology
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    • v.5 no.6
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    • pp.15-24
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    • 1996
  • In this study, as a part of the basic study for the application of optical fiber sensors to smart composite structures, the integrity of optical fiber sensors embedded within the composite structures was examined and then the laser signal transmitted through optical fiber sensors during the deformation of host structures was investigated. Firstly, it was found that bending test could be substituted for tensile test by comparing cumulative failure distribution based on weakest link theory and introducing the correction factor. Weibull parameters were obtained through the experiments and the correction factor was found to be applied to cumulative failure distribution derived from bending test. The integrity of embedded optical fiber sensors due to the thermal effect was evaluated by the comparison of the mean tensile strengths of cured and uncured optical fibers. Secondly, relationships between stress-strain curve obtained in tensile test of composite laminate and the intensity of laser signal transmitted through embedded optical fibers were examined and the possibility of the effective damage detection using optical fiber sensors was studied.

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Investigation of Fatigue Strength and Prediction of Remaining Life in the Butt Welds Containing Penetration Defects (블완전용입 맞대기 용접재의 용입깊이에 따른 피로강도특성 및 잔류수명의 산출)

  • Han, Seung Ho;Han, Jeong Woo;Shin, Byung Chun
    • Journal of Korean Society of Steel Construction
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    • v.10 no.3 s.36
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    • pp.423-435
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    • 1998
  • In this paper fatigue strength reduction of butt weld with penetration defect, which can be seen frequently in the steel bridge, was assessed quantitatively. S-N curves were derived and investigated through the constant amplitude fatigue test of fully or partially penetrated welded specimen made of SWS490 steel. The fracture mechanical method was applied in order to calculate the remaining fatigue life of the partially penetrated butt welds. The fatigue limit of the fully penetrated butt welds was higher than that of category A in AASHTO's fatigue design curves, and the slope of S-N curves with 5.57 was stiffer than that of other result for welded part generally accepted as 3. The fatigue strength of the partially Penetrated butt weld was strongly influenced by the size of lack of penetration, D. It decreased drastically with increasing D from 3.9 to 14.7mm. Fracture behaviour of the partially penetrated butt weld is able to be explained obviously from the beach mark test that a semi-elliptical surface crack with small a/c ratio initiates at a internal weld root and propagates through the weld metal. To estimate the fatigue life of the partially penetrated butt weld with fracture mechanics, stress intensity factors K of 3-dimensional semi-elliptical crack were calculated by appling finite elements method and fracture mechanics parameters such as C and m were derived through the fatigue test of CT-specimen. As a result, the fatigue lives obtained by using the fracture mechanical method agreed well with the experimental results. The results were applied to Sung-Su bridge collapsed due to penetration defects in butt weld of vertical member.

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Development and Application of Mode II Fracture Toughness Test Method Using Rock Core Specimen (시추코어를 이용한 암석의 mode II 파괴인성 시험법 개발과 적용)

  • Jung, Yong-Bok;Park, Eui-Seob;Kim, Hyunwoo
    • Tunnel and Underground Space
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    • v.26 no.5
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    • pp.396-408
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    • 2016
  • Rock fracture mechanics has been widely applied to various fields of rock and civil engineering. But most researches covered mode I behavior, though mode II behavior is dominant in rock engineering. Until now, there is only one ISRM suggested method for mode II toughness of rock. A new SCC (Short Core in Compression) mode II toughness test method was developed considering 1) application of confining pressure, 2) easiness of notch creation, 3) utilization of existing equipment, 4) simple test procedure. The stress intensity factors were determined by 3D finite element method considering line and distributed loading conditions. The tests with granite specimens were carried out using MTS 815 rock test system with a loading rate of 0.002 mm/s. The mean value of mode II fracture toughness of granite showed $2.33MPa{\sqrt{m}}$. Mode I toughness of the same granite was $1.12MPa{\sqrt{m}}$, determined by Brazilian disk test and $K_{IIC}/K_{IC}=2.08$. The smooth fracture surface with rock powder formation also supported mode II behavior of SCC method. The SCC method can be used for the determination of mode II fracture toughness of rocks based on the current results.

Prediction of Transmission Error Using Dynamic Analysis of a Helical Gear (헬리컬기어의 동적해석을 통한 전달오차 예측)

  • Lee, Jeongseok;Yoon, Moonyoung;Boo, Kwangsuk;Kim, Heungseob
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.40 no.12
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    • pp.1005-1011
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    • 2016
  • The fundamental reason for gear noise is transmission error. Transmission error occurs because of STE (static transmission error) and DTE (dynamic transmission error), while a pair of gears is meshing. These errors are generated by the deflection of the teeth and the friction on the surface of the teeth. In addition, the vibration generated by transmission error leads to excited bearings. The bearings support the shafts, and the noise is radiated after exciting the gear casing. The analysis of the contact stress in helical gear tooth flanks indicates that it is due to impact loading, such as the sudden engagement and disengagement of a gear. Stress analysis is performed for different roll positions, in order to determine the most critical roll angle. Dynamic analysis is performed on this critical roll position, in order to evaluate variation in stresses and tooth contact force, with respect to time. In this study, transmission error analysis was implemented on a spur and helical gear with involute geometry and a modified geometry profile. In addition, in order to evaluate the intensity of impact due to sudden engagement and significant backlash, the impact factor was calculated using the finite element analysis results of static and dynamic maximum bending stresses.

The Assessment of Photochemical Index of Nursery Seedlings of Cucumber and Tomato under Drought Stress (건조스트레스에 의한 오이와 토마토 공정육묘의 광화학적 지표 해석)

  • Ham, Hyun Don;Kim, Tae Seong;Lee, Mi Hyun;Park, Ki Bae;An, Jae-Ho;Kang, Dong Hyeon;Kim, Tae Wan
    • Korean Journal of Environmental Biology
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    • v.36 no.4
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    • pp.479-487
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    • 2018
  • The purpose of this study is to analyze photochemical activity of nursery seedlings under drought stress, using chlorophyll fluorescence reaction analysis. Young nursery seedlings of tomato (Lycopersicon esculentum Mill.) and cucumber (Cucumis sativa L.), were grown under drought stress for 8 days. Analysis of chlorophyll fluorescence reaction (OJIP) and parameters, were performed to evaluate photochemical fluctuation in nursery seedlings under drought stress. Chlorophyll fluorescence reaction analysis showed maximal recorded fluorescence (P) decreased from the 5 day after treatment in tomato seedlings, while an amount of chlorophyll fluorescence increased at the J-I step. Thus, physiological activity was reduced. In cucumber seedlings, maximal recorded fluorescence (P) and maximal variable fluorescence ($F_V$) lowered from the 4 day after treatment, and chlorophyll fluorescence intensity of J-I step increased. Chlorophyll fluorescence parameter analysis showed electron transfer efficiency of PSII and PSI were significantly inhibited with decreasing $ET2_O/RC$ and $RE1_O/RC$ from the 5 day after treatment, in tomato seedlings and from the 4 day after treatment, in cucumber seedlings. $ET2_O/RC$ and $PI_{ABS}$ significantly changed. In conclusion, 6 indices such as $F_V/F_M$, $DI_O/RC$, $ET2_O/RC$, $RE1_O/RC$, $PI_{ABS}$ and $PI_{TOTAL}ABS$ were selected for determining drought stress in nursery seedlings. Drought stress factor index (DFI) was used to evaluate whether the crop was healthy or not, under drought stress. Cucumber seedlings were less resistant to drought stress than tomato seedlings, in the process of drought stress.

Effect of Stress Induced Phase Transformation on $Al_2 O_3$ Matrix Dispersed with $ZrO_2-Y_2O_3$ ($Y_2O_3-ZrO_2$$Al_2 O_3$ 매트릭스에 분산시 응력 유기 상변태의 효과)

  • Lee, Tae-Keun;Lim, Eung-Keuk;Kim, Hwan
    • Journal of the Korean Ceramic Society
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    • v.22 no.1
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    • pp.11-18
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    • 1985
  • The effect of stress induced phase transformation on $Al_2 O_3$ matrix dispersed with $ZrO_2-Y_2O_3$ has been studied. In order to determinate the mechanical properties three $Al_2O_3-ZrO_2$ composite series containing 1, 3 and 5 mole% $Y_2O_3$ were prepared. The starting materials were $Al_2O_3$ and $ZrO_2-Y_2O_3$ which was prepared from the aqueous solution of high purity $YCl_3$.$6H_2O$ and $ZrOCl_2$.$8H_2O$. Powder mixtures of $Al_2O_3-ZrO_2$ containing $Y_2O_3$ have been prepared by ball-milling with methanol and the samples were formed by isostatic press and sintered at 150$0^{\circ}C$ for 2hrs. After sintering. the specimens were polished for mechanical determination. The relative density of sintered specimens were also measured. It was found that the addition of 1, 3mole% to {{{{ { ZrO}_{2 } }} allowed full retention of the tetragonal phase in $Al_2O_3-ZrO_2$ but partially stabilized zirconia (PSZ) was produced by additions of 5 mole% $Y_2O_3$.The critical stress-intensity factor KIc of $A_2O_3-ZrO_2$ (containing 1 mole% $Y_2O_3$) composite materials increased with increasing $ZrO_2$ content, The maximum value of KIC=7Mn/$m^3$/2 at 20 mole% $ZrO_2$ exhibited about twice that of the $Al_2 O_3$ The modulus of rupture exhibited a trend similiar to KIC The maximum value of MOR was 580MN/m2. As the amount of Y2O3 increase it was observed that the maximum of KIC and MOR decreased : Additions of 3 mole% $Al_2O_3$ $Y_2O_3$ allowed the maximum of KIC 6MN/$m^3$/2 MOR 540MN/$m^2$ at 15 mole% $ZrO_2$ additions of 5 mole% $Y_2O_3$ allowed the maximum of KIC 5MN/$m^3$/2 MOR 410MN/$m^2$ at 10 mole% $ZrO_2$.

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