• Computational Structural Engineering
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• v.10 no.1
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• pp.129-134
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• 1997

Interfacial stress singularity in a unidirectional two-dimensional laminate model consisting of an elastic fiber and a viscoelastic matrix has been investigated using the time-domain boundary element method. First, the interfacial singular stresses between the fiber and the matrix of a unidirectional laminate subjected to a uniform transverse tensile strain have been investigated near the free surface, but without any defect or any edge crack. Such a stress singularity might lead to fiber-matrix debonding or interfacial edge cracks. Then, the overall stress intensity factor for the case of a small interfacial edge crack of length a has been computed.

• Proceedings of the Korean Society for Technology of Plasticity Conference
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• 2008.05a
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• pp.288-292
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• 2008

Plastics is commonly used in consumer electronics because of it is high strength per unit mass and good productivity. But plastic parts are usually distorted after injection molding due to the residual stress after filling, packing, cooling process, and etc. And plastic material is to be deteriorated according to various temperature conditions and operating time, which can be characterized by stress relaxation and creep. The viscoelastic behaviour of plastic materials in time domain can be expressed by the Prony series of the commercial code, ABAQUS. In the paper, the process to predict the post deformation under cyclic thermal loadings was suggested. The process was applied to the real panel, and the deformation predicted by the analysis was compared with that of real test, which showed the possibility of applying the suggested process to predict the post deformation of plastic product under thermal loadings.

• Steel and Composite Structures
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• v.38 no.4
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• pp.355-363
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• 2021

The present paper attempts to investigate the propagation of plane waves in an isotropic elastic medium under the effect of initial stress and temperature-dependent properties. The modulus of elasticity is taken as a linear function of the reference temperature. The formulation is applied under the thermoelasticity theory with dual-phase-lag; the normal mode analysis is used to obtain the expressions for the displacement components, the temperature, the stress, and the strain components. Numerical results for the field quantities are given in the physical domain and illustrated graphically. Comparisons are made with the results predicted by different theories (Lord-Shulman theory, the classical coupled theory of thermoelasticity and the dual-phase-lag model) in the absence and presence of the initial stress as well as the case where the modulus of elasticity is independent of temperature.

• Genomics & Informatics
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• v.6 no.2
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• pp.72-76
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• 2008

Hypoxia-inducible factor $1{\alpha}\;(HIF1{\alpha})$ is a transcription factor that plays a key role in the adaptation of cells to low oxygen stress and oxygen homeostasis. The oxygen-dependent degradation (ODD) domain of $HIF1{\alpha}$ is responsible for the negative regulation of $HIF1{\alpha}$ in normoxia. The interactions of the $HIF1{\alpha}$ ODD domain with partner proteins such as von Hippel-Lindau tumor suppressor (pVHL) and p53 are mediated by two sequence motifs, the N- and C-terminal ODD(NODD and CODD). Multiple sequence alignment with $HIF1{\alpha}$ homologs from human, monkey, pig, rat, mouse, chicken, frog, and zebrafish has demonstrated that the NODD and CODD motifs have noticeably high conservation of the primary sequence across different species and isoforms. In this study, we carried out molecular dynamics simulation of the structure of the $HIF1{\alpha}$ CODD motif in complex with the p53 DNA-binding domain (DBD). The structure reveals specific functional roles of highly conserved residues in the CODD sequence motif of $HIF1{\alpha}$ for the recognition of p53.

• Molecules and Cells
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• v.27 no.4
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• pp.493-496
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• 2009

Hypoxia-inducible factor $1{\alpha}$ ($HIF1{\alpha}$) is a transcription factor that plays a key role in the adaptation of cells to low oxygen stress and oxygen homeostasis. The oxygen-dependent degradation (ODD) domain of $HIF1{\alpha}$ responsible for the negative regulation of $HIF1{\alpha}$ in normoxia is intrinsically unfolded. Here, we carried out the backbone $^1H$, $^{15}N$, and $^{13}C$ resonance assignment of a proteolysis-resistant fragment (residues 404-477) in the $HIF1{\alpha}$ ODD domain using NMR spectroscopy. About 98% (344/352) of all the $^1HN$, $^{15}N$, $^{13}C{\alpha}$, $^{13}C{\beta}$, and $^{13}CO$ resonances were unambiguously assigned. The results will be useful for further investigation of the structural and dynamic states of the $HIF1{\alpha}$ ODD domain and its interaction with binding partners.

• The Korean Journal of Health Service Management
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• v.7 no.2
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• pp.135-148
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• 2013

The aim of this study is to analyze affecting factor on the job finding stress of university students majoring occupational therapy. We collected data for 7days from 12 to 19 July, 2012. This study was surveyed 270 university students majoring occupational therapy was located in the Pusan and South Kyungnam region. It was found that mean score of the job find stress was $2.12{\pm}0.57$. There was statistically significant difference in the physical symptom, depression, anxiety and sub-domain on the job finding stress by gender, age, the economic status, region of birth, the state of employment, employment determinants, job finding stress relief, advice for job finding(p<0.05). From the multiple regression analysis, it was found that affecting factor on the job finding stress was personal characteristics, job related characteristics, stress relief characteristics, physical symptom, depression, anxiety which was statistically significant difference(p<0.05). As a result, we could know that they must relieve the physical symptom, depression and anxiety for lowering job finding stress of university student majoring occupational student.

• Korean Journal of Health Education and Promotion
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• v.26 no.4
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• pp.63-70
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• 2009

Objectives: Work stress is associated with increased risk of fatigue. The purpose of this study was to identify the relationship of work stress and fatigue among Medical Insurance Review Nurses. Methods: The subjects of this study were 117 nurses in charge of medical insurance review. A structured questionnaires were employed to evaluate the nurses' sociodemographics, work stress and fatigue. The data were analysed through frequency, percentile, mean, standard deviation, Chronbach's $\alpha$, Pearson's correlation coefficient, and multiple regression. Results: Mean scores of work stress and fatigue of participants were 3.29 and 1.97 respectively. Work stress was correlated with fatigue significantly (r=.39). There were effects on fatigue by work performance satisfaction and the frequency of insurance request among sociodemographics. Job conflicts with doctors which was a domain of work stress was increased fatigue. Conclusion: The results of this study suggest that work performance satisfaction, the frequency of insurance request and job conflicts with doctors are significant predictors of fatigue. Thus, a strategy to enhance nurses' work environment and to reduce work stress through developing interpersonal relationship is recommended.

• Proceedings of the Materials Research Society of Korea Conference
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• 1994.11a
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• pp.133-136
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• 1994

A microcechanical analysis based on the single fiber model has studied in the standpoint of stress-strain hysteresis response. A comparative study of constraint and unconstraint effects ha been taken into account to investigate includes the stress grouping technique to evaluate the domain-based field quantities. Results indicated that the development of significant fiber stresses both for the tensile and compressive loading, due to the constraint effects, provides an important contribution to the composited strengthening

• Advances in nano research
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• v.6 no.1
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• pp.39-55
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• 2018

Forced vibration analysis of a cracked functionally graded microbeam is investigated by using modified couple stress theory with damping effect. Mechanical properties of the functionally graded beam change vary along the thickness direction. The crack is modelled with a rotational spring. The Kelvin-Voigt model is considered in the damping effect. In solution of the dynamic problem, finite element method is used within Timoshenko beam theory in the time domain. Influences of the geometry and material parameters on forced vibration responses of cracked functionally graded microbeams are presented.

• Proceedings of the Computational Structural Engineering Institute Conference
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• 1999.04a
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• pp.19-26
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• 1999

This paper deals with the stress singularity induced at the interface corner between the viscoelastic thin film and the rigid substrate as the film absorbs moisture from the ambient environment. The rime-domain boundary element method is employed to investigate the behavior of interface stresses. The order of the free-edge singularity is obtained numerically for a given viscoelastic model. It is shown that the free-edge stress intensity factor is relaxed with time,'while the order of the singularity increases with time for the viscoelastic model considered.