• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.20 no.3
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• pp.152-157
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• 2009

Objectives : We investigated the parenting stress and depressive mood of mothers with developmentally-delayed children and the effects of participation in a mother-child development promotion program on same. Methods : Subjects were the mothers of 20 developmentally-delayed children. The severity of the mothers' parenting stress was evaluated via the Korean version of the Parenting Stress Index, Short Form (K-PSI-SF) and the severity of their depressive symptoms were evalueted by the Korean version of the Beck Depression Inventory (K-BDI). Results : The mean K-PSI-SF score and mean K-BDI score for these mothers were 93.35 (SD=10.47) and 23.25 (SD=10.42), respectively. These scores correspond to high parenting stress and moderate depression. The mothers who participated in a mother-child attachment- promotion program showed significant decreases in their K-PSI-SF and KBDI scores. Conclusion : Our data suggest that a mother-child attachment promotion program with emphasis on child development is effective in reducing parenting stress and depressive mood in mothers of developmentally-delayed children.

• Geomechanics and Engineering
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• v.22 no.2
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• pp.187-196
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• 2020

The changeable stress environment directly affect the propagation law of a stress wave. Stress wave propagation tests in sandstone with different axial stresses were carried using a modified split Hopkinson Pressure bar (SHPB) assuming the sandstone has a uniform pore distribution. Then the waveform and stress wave energy dissipation were analyzed. The results show that the stress wave exhibits the double peak phenomenon. With increasing axial stress, the intensity difference decreases exponentially and experiences first a dramatic decrease and then gentle development. The demarcation stress is σ/σ_c=30%, indicating that the closer to the incident end, the faster the intensity difference attenuates. Under the same axial stress, the intensity difference decreases linearly with propagation distance and its attenuation intensity factor displays a quadratic function with axial stress. With increasing propagation distance, the time difference decays linearly and its delay coefficient reflects the damage degree. The stress wave energy attenuates exponentially with propagation distance, and the relations between attenuation rate, attenuation coefficient and axial stress can be represented by the quadratic function.

• Child Health Nursing Research
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• v.22 no.3
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• pp.163-171
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• 2016

Purpose: This study was done to explore disease factors in children with epilepsy, parental factors and resource factors that are related to parenting stress and identify effects of each factor on parenting stress. Methods: Participants were 131 parents who had children who visited a hospital or were hospitalized due to epilepsy. Data collection was done between September 17 and November 17, 2012, and self-report surveys were used. Results: In Stepwise multiple regression analysis, factors influencing parenting stress in children with epilepsy were marital communication, educational background of parents, parenting efficacy, children's development delay, drug treatment and surgical treatment as a method of epilepsy treatment. These factors explained 34.6% (F=13.22, p<.001) of the variance in parenting stress. Conclusion: The findings indicate that parental factors (educational background of parents and parenting efficacy) and resource factors (marital communication) have higher explanatory power than disease factors of the children. Thus, it is importance to assess the capacity of parents through self-evaluation, and to assess barriers to marital communication when developing parenting stress intervention programs. Furthermore, both parents should be involved in interventions for parenting stress.

• The Journal of Korean Academy of Sensory Integration
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• v.21 no.3
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• pp.1-12
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• 2023

Objective : The purpose of this study was to compare the effects of the sensory processing characteristics of parents of developmentally delayed children and parents of typically developed children on parenting stress. Methods : From July to August 2022, 61 parents of children with developmental delays and 64 parents of children with typical development who used occupational therapy services at pediatric clinics and child development centers were evaluated for parenting stress and sensory profiles. Results : In a multiple regression analysis on the effect of sensory processing characteristics on the total score of parenting stress, tactile processing (β = 0.353, p = 0.001), gender (β = 0.438, p = 0.000), and monthly income (β = -0.261, p = 0.014) significantly affected the parenting stress of the parents of children with developmental delay. In parents of typically developing children, tactile processing (β = 0.376, p = 0.002) and gender (β = -0.264, p = 0.024) were found to have a significant effect on parenting stress. Conclusion : Parental gender and tactile processing characteristics of developmentally delayed and typically developing children are significant influencing factors for parenting stress.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.67 no.6
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• pp.794-798
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• 2018

There is a growing need for a care system that can continuously monitor, manage and effectively relieve stress for modern people. In recent years, mobile healthcare devices capable of measuring heart rate have become popular, and many stress monitoring techniques using heart rate variability analysis have been actively proposed and commercialized. In addition, respiratory biofeedback methods are used to provide stress relieving services in environments using mobile healthcare devices. In this case, breathing information should be measured well to assess whether the user is doing well in biofeedback training. In this study, we extracted the heart beat interval signal from the PPG and used the oscillator based notch filter based on the IIR band pass filter to track the strongest frequency in the heart beat interval signal. The respiration signal was then estimated by filtering the heart beat interval signal with this frequency as the center frequency. Experimental results showed that the number of breathing could be measured accurately when the subject was guided to take a deep breath. Also, in the timeing measurement of inspiration and expiration, a time delay of about 1 second occurred. It is expected that this will provide a respiratory biofeedback service that can assess whether or not breathing exercise are performed well.

• Natural Product Sciences
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• v.12 no.4
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• pp.175-192
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• 2006

Screening for the cytotoxicity from plant origin is the first stage for anti-cancer drug development. A variety of terpenoids with exomethylene, epoxide, allyl, $\alpha,\beta-unsaturated$ carbonyl, acetylenes, and $\alpha-methylene-\gamma-lactone$ induces apoptosis and/or differentiation as well as cytotoxicity through the ROS signal transduction pathways. These are found among monoterpenes, sesquiterpenes, triterpenes, flavonoids, coumarins, diarylheptanoids, and even organosulfuric compounds. The most essential characteristics of natural cytotoxic substances is to possess the strong electrophilicity that is susceptible to nucleophilic biomolecules in the cell. Thiol-reductants and superoxide dismutase can block or delay apoptosis. Thus, ROS and the resulting cellular redox-potential changes can be parts of the signal transduction pathway during apoptosis. Disturbance of the balance of oxireduction by the pigment of natural quinones also caused the induction of the differentiation and apoptosis. Saponins with the cytotoxicity are restricted to their monodesmosides, rather than to bisdesmosides. Those saponins exhibited calcium ion-mediated apoptosis in addition to cytotoxicity whereas they showed also differentiation without extracellular calcium ion. The properties on cytotoxicity, apoptosis, and differentiation were assumed to depend on resultant oxidative stress to the cells. In this review, we describe a spectrum of cytotoxic compounds with various action mechanisms.

• Mycobiology
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• v.51 no.5
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• pp.273-280
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• 2023

The nucleolus is the largest, membrane-less organelle within the nucleus of eukaryotic cell that plays a critical role in rRNA transcription and assembly of ribosomes. Recently, the nucleolus has been shown to be implicated in an array of processes including the formation of signal recognition particles and response to cellular stress. Such diverse functions of nucleolus are mediated by nucleolar proteins. In this study, we characterized a gene coding a putative protein containing a nucleolar localization sequence (NoLS) in the rice blast fungus, Magnaporthe oryzae. Phylogenetic and domain analysis suggested that the protein is orthologous to Rrp8 in Saccharomyces cerevisiae. MoRRP8-GFP (translational fusion of MoRRP8 with green fluorescence protein) co-localizes with a nucleolar marker protein, MoNOP1 fused to red fluorescence protein (RFP), indicating that MoRRP8 is a nucleolar protein. Deletion of the MoRRP8 gene caused a reduction in vegetative growth and impinged largely on asexual sporulation. Although the asexual spores of DMorrp8 were morphologically indistinguishable from those of wild-type, they showed delay in germination and reduction in appressorium formation. Our pathogenicity assay revealed that the MoRRP8 is required for full virulence and growth within host plants. Taken together, these results suggest that nucleolar processes mediated by MoRRP8 is pivotal for fungal development and pathogenesis.

• Structural Engineering and Mechanics
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• v.63 no.4
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• pp.447-456
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• 2017

The primary objective of this paper is to study the effectiveness of anchorage on the performance of shear deficient beams externally strengthened with CFRP composites. The overall behavior of the tested beams loaded up to failure, the onset of the cracking, and crack development with increased load and ductility were described. The use of CFRP composites is an effective technique to enhance the shear capacity of RC beams by using CFRP strips anchored into the tension side and from the top by 15-34% based on the investigated variables. Bonded anchorage of CFRP strips with width of 0.1h-0.3h to the beam resulted in a decrease in average interface bond stress and an increase in the effective strain of the FRP sheet at failure, which resulted in a higher shear capacity as compared with that of the U-wrapped beams without anchorage as well as delay or mitigate the sheet debonding from the concrete surface.

• Journal of Families and Better Life
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• v.31 no.1
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• pp.11-27
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• 2013

The purpose of this study was to investigate the overall developmental characteristics of Korean children ages 0 to 8, and then explore specifically how children's social and emotional developmental levels are related to mothers' psychological states. This study was part of newly launched Boryung Baby Panel Study using web-based survey in 2011. The subjects were all mothers of 940 infants(0-2 years), 654 toddlers(3-5 years), and 484 school-age children(6-8 years) The mothers were asked to administer the web-based standardized developmental checklist for their child and fill out the questionnaires of psychological variables(life satisfaction, depression, parenting attitude, parenting efficacy, and parenting stress). The data was analyzed using descriptive analysis, t-test, and logistic regression for SPSS 20.0 windows. Major findings were as follows: 1. Infants(0 to 2) showed higher developmental level in cognition and fine motor skill domain compared to other domains. 2. Most toddlers(3 to 5) showed normal development in the most domain such as gross motor skill, fine motor skill, language, letter, number, self-help behavior. 3. In socio-emotional development domain, the ratio of risk or delay group were highest at both infant and toddler. 4. The 6-8 years old children that belong to risk group by the result of SDQ(emotion and behavior assessment) were also relatively high. 5. The relation of the children's socio-emotional developmental level and the mother's psychological variables were reciprocal. Based on these findings, the implications and the limitations of current study were discussed.

• Journal of the korean society of oceanography
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• v.37 no.3
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• pp.91-107
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• 2002

The wintertime upwind flow in the Yellow Sea has been investigated through a series of two-dimensional numerical experiments in an idealized basin. A total of 10 experiments have been carried out to examine the effects of wind forcing, bottom friction and the presence of oceanic currents sweeping the shelf of the East China Sea. A spatially uniform steady and periodic wind stresses are considered along with comparison of linear and quadratic formulations. The wind-driven flow in the absence of oceanic current has been computed using Proudman open boundary condition (POBC), while the wind-driven current in the presence of oceanic current has been computed using Flather’s radiation condition (FOBC). The oceanic currents to be prescribed at the open boundary have been simulated by specifying uniform sea level gradients across the Taiwan Strait and the eastern ECS shelf, Calculations show that, as seen in Lee et al. (2000), oceanic flow little penetrates into the Yellow Sea in the absence of wind forcing unless a unrealistically low rate of bottom frictional dissipation is assumed. Both steady and time-periodic wind stresses invoke the upwind flow along the central trough of the Yellow Sea, independently of the presence of the oceanic current. The presence of oceanic currents very marginally alters the north-south gradient of the sea surface elevation in the Yellow Sea. Changes in the intensity and direction of the wind-induced mean upwind flow are hardly noticeable in the Yellow Sea but are found to be significant near Cheju Island where the gradient is reduced and therewith contribution of Ekman transport increases. In case of steady wind forcing circulation patterns such as two gyres on the slope sides, a cyclonic gyre on the western slope and an anticyclonic gyre on the eastern slope persist and the upwind flow composes part of the cyclonic gyre in the Yellow Sea. While in case of the time-periodic wind stress the appearance and disappearance of the patterns are repeated according to the time variation of the wind stress and the upwind flow accordingly varies with phase delay, mostly intensifying near the time when the wind forcing is approximately near the middle of the decaying stage.