• Journal of the Korean Society of Hazard Mitigation
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• v.1 no.1 s.1
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• pp.117-125
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• 2001

This paper presented the analysis of stress regimes in and around inactive and active fault zones. The stress regime in the vicinity of an existing inactive fault zone is dependent on the orientation of the fault with respect to the current stress field and the contrast between the elastic properties of the faulted rock and those of the surrounding rock. In the analysis of stress regimes around an active fault zone, if the yielding stress is exceeded during loading, the localized shearing in a fault zone will result in weakness with mean stresses in the fault becoming lower than those in the surrounding rock. It can be expected that such stress gradients will induce fluid flow towards the faults zone.

• Proceedings of the Korea Concrete Institute Conference
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• 2009.05a
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• pp.373-374
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• 2009

Three autogenous expansion model of MgO concrete are investigated in order to access their suitability in stress analysis which consider temperature and volume change due to hydration of cement and temperature dependent expansion of MgO.

• Food Science and Biotechnology
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• v.17 no.1
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• pp.106-113
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• 2008

The antioxidant and anti-inflammatory protective effects of $\beta$-glucan from barley on RAW 264.7 murine macrophage cells induced by lipopolysaccharide (LPS) were examined. The RAW 264.7 murine macrophages were preincubated with various concentrations ($0-200\;{\mu}g/mL$) of $\beta$-glucan and stimulated with LPS to induce oxidative stress and inflammation. The $\beta$-glucan treatments were found to reduce thiobarbituric acid-reactive substance (TBARS) accumulation, and enhance glutathione levels and the activities of antioxidative enzymes, including superoxide dismutase (SOD), catalase, glutathione reductase, and glutathione peroxidase (GSH-px) in the LPS-stimulated macrophages as compared to the LPS-only treated cells. Nitric oxide (NO) production was significantly suppressed in a dose-dependent manner (p<0.05) with an $IC_{50}$ of $104\;{\mu}g/mL$. Further treatment with $\beta$-glucan at $200\;{\mu}g/mL$ suppressed NO production to 2% of the LPS-control, and suppressed the levels of inducible nitric oxide synthase (iNOS) protein and mRNA in a dose-dependent manner. The specific DNA binding activity of nuclear factor ${\kappa}B\;(NF{\kappa}B)$ was significantly suppressed by $\beta$-glucan treatment with an $IC_{50}$ of $220\;{\mu}g/mL$ in a dose-dependent manner. Finally, barley $\beta$-glucan ameliorates NO production and iNOS expression through the down-regulation of $NF{\kappa}B$ activity, which may be mediated by attenuated oxidative stress in RAW 264.7 macrophages.

• KSBB Journal
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• v.8 no.5
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• pp.424-430
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• 1993

The anti-stress effect by the treatment of vitamin C was investigated in this study. The treatment of ascorbic acid in the presence of $Cu^{2+}$ion induced strong time- and dose-dependent degradation of hitamine, and also the addition of histamine accelerated time-dependent decomposition of ascorbic acid in vitro. The treatment of ascorbic acid in $ODS^{od}/_{od}$rats, which cannot synthesize ascorbic acid, significantly decreased the urinary histamine. The protreatment of ascorbic acid, dexamethasone and promethazine inhibited the lethal effect induced by immobilization stress, but that of dimethylsulfoxide did not. The addition of ascorbic and to a culture of spleen cells of $ODS^{od}/_{od}$rats significantly increased the Con A-dependent T lymphocyte proliferation.

• Tunnel and Underground Space
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• v.13 no.1
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• pp.44-51
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• 2003

Changes of the hydraulic conductivity resulting from the redistribution of stresses by underground excavation are examined using the strain-dependent hydraulic conductivity modification relation, where the modulus reduction ratio and induced strain are the major parameters. The modulus reduction ratio is defined in terms of RMR(Rock Mass Rating) to represent the full gamut of rock mass condition. Though shear dilation has the effect on the modification of hydraulic conductivity, the extent of it depends on RMR When the extensional strain is applied to a fracture, the hydraulic conductivity increases with the decrease of RMR Loading configuration has the effect on the modification of hydraulic conductivity, where the differential stress mode with a magnitude of the minimum principal stress $($\sigma$_x)$ fixed and a magnitude of the maximum principal stress $($\sigma$_y)$ varied is found to exert the greatest effect on the change of hydraulic conductivity.

• Transactions of Materials Processing
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• v.20 no.3
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• pp.229-235
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• 2011

The formability of magnesium alloy sheets at room temperature is generally low because of the inherently limited number of slip systems, but higher at temperatures over $150^{\circ}C$. Therefore, prior to the practical application of these materials, the forming limits should be evaluated as a function of the temperature and strain rate. This can be achieved experimentally by performing a series of tests or analytically by deriving the corresponding modeling approaches. However, before the formability analysis can be conducted, a model of flow stress, which includes the effects of strain, strain rate and temperature, should be carefully identified. In this paper, such procedure is carried out for Mg alloy AZ31 and the concept of flow stress surface is proposed. Experimental flow stresses at four temperature levels ($150^{\circ}C$, $200^{\circ}C$, $250^{\circ}C$, $300^{\circ}C$) each with the pre-assigned strain rate levels of $0.01s^{-1}$, $0.1s^{-1}$ and $1.0s^{-1}$ are collected in order to establish the relationships between these variables. The temperature-compensated strain rate parameter which combines, in a single variable, the effects of temperature and strain rate, is introduced to capture these relationships in a compact manner. This study shows that the proposed concept of flow stress surface is practically relevant for the evaluation of temperature and strain dependent formability.

• Geomechanics and Engineering
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• v.11 no.4
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• pp.531-552
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• 2016

The greenschist in the Jinping II Hydropower Station in southwest China exhibits continuous creep behaviour because of the geological conditions in the region. This phenomenon illustrates the time-dependent deformation and progressive damage that occurs after excavation. In this study, the responses of greenschist to stress over time were determined in a series of laboratory tests on samples collected from the access tunnel walls at the construction site. The results showed that the greenschist presented time-dependent behaviour under long-term loading. The samples generally experienced two stages: transient creep and steady creep, but no accelerating creep. The periods of transient creep and steady creep increased with increasing stress levels. The long-term strength of the greenschist was identified based on the variation of creep strain and creep rate. The ratio of long-term strength to conventional strength was around 80% and did not vary much with confining pressures. A quantitative method for predicting the failure period of greenschist, based on analysis of the stress-strain curve, is presented and implemented. At a confining pressure of 40 MPa, greenschist was predicted to fail in 5000 days under a stress of 290 MPa and to fail in 85 days under the stress of 320 MPa, indicating that the long-term strength identified by the creep rate and creep strain is a reliable estimate.

• Journal of the Korean Geotechnical Society
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• v.19 no.5
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• pp.291-299
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• 2003

The effect of temperature and soil confining stress on geosyntheic creep behaviour was studied by performing the temperature dependent confined creep tests for HDPE geogrid and geomembrane specimen. The visco-elastic creep coefficients of the geosynthetics were evaluated by the test results and it was proposed that the simple expressions for the instantaneous and limit creep strain of geosynthetics was considered as a function of temperature and confining stress on geosynthetics. Based on the time-temperature superposition principle, a master curve has been drawn for extrapolating tensile creep strains to longer time intervals(1$\times$10 $^7$min.∼1$\times$10$^{10}$min.). By using this master curves, the shift factors which can be used in establishing master curve considering confining stress on geosynthetics were carried out. Each tests was performed during 8,000∼12,000 min., with temperature ranging between 5$^{\circ}C$ and 4$0^{\circ}C$ and with confining stress ranging between 0 t/$m^2$ and 9 t/$m^2$.

• Composites Research
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• v.33 no.1
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• pp.30-37
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• 2020

Stress distributions dependent on fiber arrangements are studied using the two-dimensional representative volume element (RVE) model for uni-directionally continuous fiber-reinforced composites subjected to transverse tensile loading. It is easily expected that the stresses around the fibers are concentrated mainly due to the stiffness mismatch between the fiber and matrix materials. In this presentation, it is shown that the stresses are not always increased although the distance between two fibers is shortened. The 2D RVE models, originally having a regular hexagonal fiber array, is utilized to study the effect of the fiber locations on the stress distributions. As the central fiber is relocated, the stress distributions around the fiber are obtained through finite element analysis. It is found that the stresses around the fiber are strongly dependent on the fiber distance as well as the angle between the loading direction and the line connecting two fibers.

• Food Science and Biotechnology
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• v.16 no.2
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• pp.205-211
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• 2007

This study was designed to investigate the suppressive effect of chlorophyll a on nitric oxide (NO) production and intracellular oxidative stress. In addition, chlorophyll a regulation of nuclear factor (NF) ${\kappa}B$ activation and inducible NO synthase (iNOS) expression were explored as potential mechanisms of NO suppression in a lipopolysaccharide (LPS)-stimulated macrophage cell line. RAW 264.7 murine macrophages were preincubated with various concentrations ($0-10\;{\mu}g/ mL$) of chlorophyll a and stimulated with LPS to induce oxidative stress and inflammatory response. Treatment with chlorophyll a reduced the accumulation of thiobarbituric acid-reactive substances (TBARS), enhancing glutathione level and the activities of antioxidative enzymes including superoxide dismutase, catalase, glutathione peroxidase (GSH-px), and glutathione reductase in LPS-stimulated macrophages compared to LPS-only treated cells. NO production was significantly suppressed in a dose-dependent manner (p<0.05) with an $IC_{50}$ of $12.8\;{\mu}g/mL$. Treatment with chlorophyll a suppressed the levels of iNOS protein and its mRNA expression. The specific DNA binding activities of NFkB on nuclear extracts from chlorophyll a treated cells were significantly suppressed in a dose-dependent manner with an $IC_{50}$ of $10.7\;{\mu}g/mL$. Chlorophyll a ameliorates NO production and iNOS expression through the down-regulation of NFkB activity, which may be mediated by attenuated oxidative stress in RAW 264.7 macrophages.