• 한국세라믹학회지
• /
• 제43권9호
• /
• pp.519-526
• /
• 2006

A full-factorial design of experiments with three input factors and two levels for each factor including center points was utilized for the preparation and characterization of twelve types of $BaTiO_3$ slips for tape casting. Ceramic powders with different particle sizes, different milling methods such as high energy milling and conventional ball milling, and two types of dispersant with different polymeric species were chosen as input factors in order to investigate their effects on slip and on green tape properties. Tape casting, a small rectangular-shaped K-square preparation, characterization and quantitative data analysis using statistical software were followed. Ceramic powder was the most significant among three input factors for the output responses of slip viscosity and green tape density, showing more favorable results with large particles than with very fine ones. In addition, high energy milling for only 30 min was more efficient than 24h of conventional ball milling in terms of powder dispersion and milling. The optimum condition based on the experimental results was a slip exposed to high energy milling with large ceramic particles along with a methylethyl acetate dispersant.

• 한국지반공학회논문집
• /
• 제19권2호
• /
• pp.123-133
• /
• 2003

사면안정 신뢰성 해석을 통해 다양한 불확실성을 체계적으로 모델링할 수 있는 실용적 인 확률통계 기법을 제시한다. 새로운 제안식은, 지반성질의 확률적 특성화를 위해 공간적 변화와 공간평균으로 인한 분산감소뿐만 아니라 통계 및 측정오차까지도 고려하였다. 지진하중의 불확실성은 인공지진파를 대량으로 생성하고 이를 응답해석에 이용함으로써 반영하였다. 예제 해석결과, 한반도와 같이 지진이 활발하지 않은 지역(중약진 지진대)에서는 일반적 수준의지반성질 변화특성화가 지진위험도 특성화만큼이나 사면 파괴 위험도와 과도한 사면변형 계산값에 영향을 준다는 결론에 도달하였다.

• 한국치위생학회지
• /
• 제19권2호
• /
• pp.307-315
• /
• 2019

Objectives: The aim of this study was to investigate the characterization of composite resin inlay surface with silane and non-thermal atmospheric pressure plasma treatment. Methods: Composite resin inlay was used as a specimen, which was treated by sandblasting + silane and sandblasting + plasma. The untreated specimens were assigned to the control group. Specimens were analyzed for surface roughness, color change, and chemical composition. Statistical analyses were performed using one-way ANOVA test (p<0.05). Results: The present findings showed that the roughness and color changes of the plasma-treated surface were significantly lower than those of the silane-treated surface. In addition, a change in the chemical composition was observed on the plasma-treated surface. Conclusions: Based on the results, non-thermal atmospheric pressure plasma could be a potential tool for the cementation of composite resin inlay.

• 한국융합학회논문지
• /
• 제8권12호
• /
• pp.391-395
• /
• 2017

본 연구에서는 안경 조제 가공료와 피팅비 필요성 및 정착화에 필요한 내용에 대한 설문조사를 실시하였다. 2016년 8월 1일부터 9월 30일까지 서울, 경기 지역의 안경사 202명을 대상으로 각 설문항목을 설정하고 온라인 오프라인으로 설문조사를 실시하였다. 모든 자료의 통계처리는 Origin Pro 8.5를 사용하여 실시하였다. 안경 조제 가공료와 피팅비 도입의 필요성에 대하여서는 각각 92.1%(186명), 93.1%(188명)가 도입 필요성에 대해서 긍정적으로 평가하고 있었다. 안경 조제 가공료와 피팅비에 대한 설문분석 및 해외사례를 통해 안정화된 정책을 제공함으로써 보건의료 서비스 전문가로서 안경사의 위치를 정립하여야 할 필요가 있다고 조사되었다.

• 대한예방의학회:학술대회논문집
• /
• 대한예방의학회 1994년도 교수 연수회(환경)
• /
• pp.417-425
• /
• 1994

Although animal studies have been used most often for quantitative risk assessment, it is generally recognized that well-conducted epidemiologic studies would provide the best basis for estimating human risk. However, there are several features related to the design and analysis of epidemiologic studies that frequently limit their usefulness for quantitating risks. The lack of accurate information on exposure in epidemiologic studies is perhaps the most frequently cited limitation of these studies for risk assessment. However. other features of epidemiologic study design, such as statistical power, length of follow-up, confounding, and effect modification, may also limit the inferences that can be drawn from these studies. Furthermore, even when the aforementioned limitations are overcome, substantial uncertainty exists concerning the choice of an appropriate statistical (or biologic) model for extrapolation beyond the range of exposures observed in a particular study. This paper focuses on presenting a review and discussion of the methodologic issues involved in using epidemiologic studies for risk assessment. This review concentrates on the use of retrospective, cohort, mortality studies of occupational groups for assessing cancer risk because this is the most common application of epidemiologic data for quantitative risk assessment (QRA). Epidemiologic data should not be viewed as a panacea for the problems inherent in using animal bioassay data for QRA. Rather, information that can be derived from epidemiologic and toxicologic studies complement one another, and both data sources need to be used to provide the best characterization of human risk.

• 한국진공학회:학술대회논문집
• /
• 한국진공학회 2013년도 제44회 동계 정기학술대회 초록집
• /
• pp.278-278
• /
• 2013

최근 나노 입자의 안전성에 대한 연구가 활발하게 이루어 지고 있다. 대부분의 연구는 세포독성과 쥐에 흡입시켜 각 장기에 침착 정도를 측정하는 연구에 집중되어 있고, 나노입자의 리간드 특성에 대한 연구는 활발이 진행되고 있지 않다. 따라서 같은 나노입자를 이용한 연구결과가 다르게 나타나는 것을 종종 확인 할 수 있어서, 나노입자 특성평가의 중요성이 커지고 있다 [1,2]. 본 연구에서는 용매에 리간드가 존재하는 PEG-conjugated AuNPs과 원심분리로 용액내의 free-ligands가 제거된 PEG-conjugated AuNPs에 대하여 ToF-SIMS 이미지를 얻었고, PEG와 AuNPs 이미지의 statistical correlation으로부터 AuNPs의 표면에 존재하는 리간드들의 stability를 평가할 수 있는 방법을 개발하였다. 또한, citrated-conjugated AuNPs을 PEG 리간드로 표면을 치완시키고, phagolysosomal simulant Fulid(PSF) 용액에 incubation 과정 동안의 PEG 리간드가 표면에서 제거되어 용액에 존재함을 확인하였다. ToF-SIMS의 이미지와 statistical correlation을 이용하면 나노입자의 표면에 존재하는 다양한 리간드들의 안정성을 평가할 수 있고, 이를 통한 나노입자의 안전성에 대한 연구에 기여 할 수 있을 것으로 기대된다.

• 한국통계학회:학술대회논문집
• /
• 한국통계학회 2005년도 추계 학술발표회 논문집
• /
• pp.31-36
• /
• 2005

An identification and characterization of susceptibility genes for common complex multifactorial diseases is a challengeable task, in which the effect of single genetic variation will be likely dependent on other genetic variations(gene-gene interaction) and environmental factors (gene-environment interaction). To address is issue, the multifactor dimensionality reduction (MDR) has been proposed and implemented by Ritchie et al. (2001), Moore et al. (2002), Hahn et al.(2003) and Ritchie et al. (2003). With MDR, multilocus genotypes effectively reduce the dimension of genotype predictors from n to one, which improves the identification of polymorphism combinations associated with disease risk. However, MDR cannot handle missing observations appropriately, in which missing observation is treated as an additional genotype category. This approach may suffer from a sparseness problem since when high-order interactions are considered, an additional missing category would make the contingency table cells more sparse. We propose a new MDR approach with minimum loss of sample sizes by considering missing data over all possible multifactor classes. We evaluate the proposed MDR by using the prediction errors and cross validation consistency.

• 상하수도학회지
• /
• 제30권4호
• /
• pp.417-425
• /
• 2016

Desalination is a key technology to overcome water shortage problem in a near future. High energy consumption is an Achilles' heel in desalination technology. Osmotically driven membrane processes like forward osmosis(FO) was introduced to address this energy issue. Characterizing membrane properties such as water permeability(A), salt permeability(B), and the resistance to salt diffusion within the support layer($K_{ICP}$) are very important to predict the performance of scaled-up FO processes. Currently, most of researches reported that the water permeability of FO membrane was measured by reverse osmosis(RO) type test. Permeating direction of RO and FO are different and RO test needs hydraulic pressure so that several problems can be occurred(i.e. membrane deformation, compaction and effect of concentration polarization). This study focuses on measuring water permeability of FO membrane by FO type test results in various experimental conditions. A statistical approach was developed to evaluate the three FO membrane properties(A, B, and $K_{ICP}$) and it predicted test result by the internal and external concentration polarization model.

• Mass Spectrometry Letters
• /
• 제12권2호
• /
• pp.41-46
• /
• 2021

Collision-induced dissociation (CID) and higher-energy collisional dissociation (HCD) are the widely used fragmentation technique in mass spectrometry-based proteomics studies. Understanding the fragmentation pattern from the tandem mass spectra using statistical methods helps to implement efficient spectrum analysis algorithms. The study characterizes the frequency of occurrence of multi-charged fragment ions and their neutral loss events of doubly and triply charged peptides in the CID and HCD spectrum. The dependency of the length of the fragment ion on the occurrence of multi-charged fragment ion is characterized here. Study shows that the singly charged fragment ions are generally dominated in the doubly charged peptide spectrum. However, as the length of the product ion increases, the frequency of occurrence of charge 2 fragment ions increases. The y- ions have more tendencies to generate charge 2 fragment ions than b- ions, both in CID and HCD spectrum. The frequency of occurrence of charge 2 fragment ion peaks is prominent upon the dissociation of the triply charged peptides. For triply charged peptides, product ion of higher length occurred in multiple charge states in CID spectrum. The neutral loss peaks mostly exist in charge 2 states in the triply charged peptide spectrum. The b-ions peaks are observed in much less frequency than y-ions in HCD spectrum as the length of the fragment increases. Isotopic peaks are occurred in charge 2 state both in doubly and triply charged peptide's HCD spectrum.

• 대한환경공학회지
• /
• 제38권2호
• /
• pp.71-78
• /
• 2016

본 연구에서는 낙동강 창녕함안보 구간의 수질을 통계분석을 이용하여 수질 특성을 파악하였다. 다양한 통계분석기법 중에서 상관분석과 주성분분석 및 요인분석을 실시하였으며, 강우에 따른 조류의 천이양상을 연구하였다. 이는 향후 창녕함안보 구간의 수질관리정책 수립을 위한 기초 자료를 구축하는데 매우 중요한 자료이다. 측정 자료의 상관성 분석 결과, 클로로필-a와 조류는 상관성이 유의하지 않게 나타났으며, 요인분석 결과로 3개의 주성분이 추출되었으며, 제 1요인으로는 COD, TOC, BOD, pH, 수온이 분류되었다. 또한, 강우에 따른 조류의 천이양상을 분석한 결과, 강우 후에는 남조류의 수중개체 농도가 감소하는 추세를 보인 반면, 규조류와 녹조류의 개체 농도는 다소 증가하였다.