• 한국컴퓨터정보학회논문지
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• 제26권8호
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• pp.165-172
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• 2021

본 연구의 고유수용성신경근촉진법이 뇌졸중 환자의 균형에 미치는 효과를 알아보기 위한 메타분석 연구이다. 이 연구는 프리지마 가이드 라인에 의해 시행되었으며, 총 3개의 데이터베이스를 이용하여 2020년 12월까지 발행된 무작위 배정 연구로 한정하여 검색하였다. 데이터베이스에서 검색된 1475개의 연구 중 본 연구 선정기준에 부합된 12편의 연구를 선정하였다. 개별 연구들의 효과크기를 산출하기 위해 R 프로그램을 이용하였다. 고유수용성신경촉진법이 뇌졸중 환자의 보행 능력에 미치는 전체 효과크기는 0.67으로 중간 정도 효과로 나타났다. 보행에 대한 하위변수에 대한 효과크기는 게이트 라이트 0.69, 10 미터 걷기 검사 0.59로 중간 정도의 효과크기로 나타났다. 이처럼 고유수용성신경근촉진법이 뇌졸중 환자의 보행 능력에 긍정적인 영향을 주었다.

• 대한방사성의약품학회지
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• 제9권1호
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• pp.3-8
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• 2023

Parkinson's disease is a neurodegenerative disease caused by damage to brain neurons related to dopamine. Non-clinical animal models mainly used in Parkinson's disease research include drug-induced models of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and 6-hydroxydopamine, and genetically modified transgenic animal models. Parkinson's diagnosis can be made using brain imaging of the substantia nigra-striatal dopamine system and using a radiotracer that specifically binds to the dopamine transporter. In this study, ¹⁸F-N-(3-fluoropropyl)-2β-carboxymethoxy-3β-(4-iodophenyl) nortropane was used to confirm the image evaluation cutoff between normal and parkinson's disease models, and to confirm model persistence over time. In addition, the efficacy of single or combined administration of clinically used therapeutic drugs in parkinson's animal models was evaluated. Image analysis was performed using the PMOD software. Converted to standardized uptake value, and analyzed by standardized uptake value ratio by dividing the average value of left striatum by the average value of right striatum obtained by applying positron emission tomography images to the atlas magnetic resonance template. The image cutoff of the normal and the parkinson's disease model was calculated as SUVR=0.829, and it was confirmed that it was maintained during the test period. In the three-drug combination administration group, the right and left striatum showed a high symmetry of more than 0.942 on average and recovered significantly. Images using ¹⁸F-N-(3-fluoropropyl)-2β-carboxymethoxy-3β-(4-iodophenyl) nortropane are thought to be able to diagnose and evaluate treatment efficacy of non-clinical Parkinson's disease.

• 대한수의학회지
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• 제63권4호
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• pp.35.1-35.10
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• 2023

Non-human primate (NHP) research faces challenges due to zoonosis risk and complex veterinary management yet lacks standardized guidelines for animal care. Therefore, we developed an advanced veterinary management protocol for NHP quarantine, anesthesia, and postoperative care. Three female 4 to 5-year-old cynomolgus monkeys were anesthetized and underwent various tests, including body weight, temperature, blood tests, urinalysis, microbiological monitoring, and physical and dental examinations. Ivermectin and medicated baths were administered to eradicate ectoparasites and endoparasites, and testing was repeated 30 days later. Following quarantine, we performed computed tomography and anesthesia maintenance for mastoidectomy. To relieve pain and maintain body weight, we administered tramadol intramuscularly 4 times/day for 3 days and meloxicam subcutaneously twice daily for 14 days. Feed replacements were provided. During the 33-day quarantine period, physical examinations revealed no abnormalities indicative of infectious diseases, and no specific clinical symptoms were observed. Through a preliminary test of anesthesia time, we selected ketamine 4 mg/kg + medetomidine 50 ㎍/kg for short experiments such as computed tomography, and ketamine 8 mg/kg + medetomidine 50 ㎍/kg for intubation. Ten days after mastoidectomy, NHPs consumed 100 kcal/kg and recovered their body weight. This study offers advanced veterinary management guideline for NHP research. Such protocols can lead to more standardized and ethical practices in NHP research, thereby enhancing the quality of studies on NHPs and the translation of findings to human health and disease.

• The International Journal of Costume Culture
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• 제8권1호
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• pp.11-22
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• 2005

The present study attempted to analyze the behavioral patterns and attitudes of high school girls toward apparel ads in magazines in relation to their physical self-concept. The study used a self-administered questionnaire. The sample consisted of 419 students at 3 girl's high schools located in Seoul. Likert scales were used for most measures with 1=never or very unimportant and 5=always or very important. Physical self-concept was measured on the basis of W S. Jung's Standardized Self-concept Test and Tennessee Self-concept Scale. Percentage, t-test, and Chi-square were used for the analysis of the data. Results are as follows: (1) Those with a high sense of physical self-concept read more magazines. (2) Those with higher sense of physical self-concept showed greater interest in magazine ads, consulted magazines for fashion trends, found ads more useful, and more often expressed satisfaction with the ads, than the lower self-concept group. (3) Advertisers should attempt to gain a deeper understanding of the socio-psychological characteristics of their readership as self-concept appeared to be related to several magazine readership attitudes and behaviors. Apparel ads targeting high school girls should consider the importance of company ads.

• 대한예방한의학회지
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• 제19권1호
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• pp.61-70
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• 2015

Objective : The aim of this study is to investigate the features of clinical trial which used symptom differentiation on cancer patients Method : Electronic databases including Ovid-Medline, Ovid-EMBASE, and Cochrane library were searched. Search terms incorporating the concepts of cancer, herbal medicine, clinical trial were used. Articles described using symptom differentiation in methods were selected. Results : Twelve studies used symptom differentiation for prescribing herbal medicine to cancer patients. A total of 36 symptom differentiation were used. The kind of the herbal medicines was varied as much as the kind of symptom differentiation. Conclusion : Most of herbal medicines used for cancer patients focused on quality of life or adverse events rather than tumor size. Symptom differentiation and herbal medicine used in selected studies were too diverse to categorize. To use standardized symptom differentiation, symptom differentiation instrument should be developed and reliability test and validity test are needed.

• 성인간호학회지
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• 제21권6호
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• pp.666-677
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• 2009

Purpose: This study was to test a theoretical model examining the relationships among social support, illness demands, marital adjustment, family coping and family functioning in couples more than three years after breast cancer diagnosis. Methods: A causal modeling methodology was used to test the specified relationships in the recursive theoretical model. A total of 60 couples with breast cancer were recruited from January to April 2005. Five standardized questionnaires were used to measure the theoretical concepts: social support (ISSB), illness demands (DOII), marital adjustment (DAS), family coping (F-COPES), and family functioning (FACESII). Results: Path analysis results from the wives and the husbands revealed different patterns. Three hypotheses were supported in the wife model as predicted: social support and family coping, family coping and family functioning, and social support and marital adjustment (trend). Five hypotheses were supported in the husband model as predicted: social support and illness demands, also social support and marital adjustment, illness demands and marital adjustment, marital adjustment and family coping, and family coping and family functioning. Conclusion: This study provides valuable information for developing various interventions with social support for improving family functioning of breast cancer couples in the middle adaption stage (more than three years after diagnosis).

• 대한간호학회지
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• 제38권1호
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• pp.83-91
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• 2008

Purpose: The purpose of this study was to test the validity of a modified clinical performance examination (CPX) for preclinical students in nursing. Method: 70 nursing students in their second semester of the junior year at C University participated in CPX. Scenarios and checklists were developed by our research team from September to October 2005. Six stations were organized. Evaluation included physical examination of a patient with lung cancer, education on usage of a metered dosage inhaler, and lobectomy postoperative care. Students were randomly assigned to a station. Result: There was a difference in the CPX scores according to stations. The agreement of scoring between trained faculty members and SPs was more than moderate (r=.647). The correlation between the CPX score and the average grade in the previous semester and between the CPX score and the average grade of a paper and pen test of the pulmonary system of adults was low (r=.276; r=.048). Conclusion: Traditional CPX is generally recommended, however, modified CPX is appropriate for preclinical students in the current Korean Nursing school setting if there are additional scoring systems to balance the testing level at each station.

• 한국실내디자인학회논문집
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• 제12호
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• pp.78-86
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• 1997

The purpose of this study was to determine the relationships between personality and interior environmental disposition, such as disposition toward traditional/modern, feminine/ masculine and simple/complex characteristics. Korean Testing Center's standardized test which measures activity, emotional stability, dominance, reflectiveness, sociability, autonomy, and achievement was used to measure personality. The three key disposition variables were measured using a visual instrument which was developed in this study. To create images, 3$\times$2$\times$2 factorial composition producing 12 types of images was used. Four set of images were developed to measure each categories of each dispositional characteristic controlling other systematic variables and extraneous variables effects. Thereby total 48 visual images were simulated. The subjects were 107 students. Data were analyzed using frequency, percentage, chi-square. test and pearson's correlation coefficients. Major findings were as follows; 1)Disposition toward oriental tradition were more likely appeared in higher emotional stability personality 2) Disposition toward tradition were more likely to be dominated than one toward modern in case of higher autonomy personality.

• 정보관리학회지
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• 제27권1호
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• pp.103-118
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• 2010

최근 특허기술의 가치평가가 크게 강조되고 있으며, 그 평가의 수단으로 특허의 피인용횟수가 매우 유용한 척도 중의 하나로 받아들여지고 있다. 그에 따라 이 연구에서는 특허의 피인용횟수와 이에 영향을 미칠만한 형태적 기술적 개념적 요인의 17개 변수들 간의 상관관계를 미국특허를 대상으로 5개 주제분야에 걸쳐 분석하였다. 분석결과 특허의 피인용횟수와 일정 수준 이상의 상관관계, 즉 5% 이상의 설명력을 갖는 변수는 페이지 수, 청구항 수, 참고문헌 평균 피인용횟수, 기술분야 특허증감율, 서지결합도, 동시인용도 및 문헌간유사도 등 7개로 나타났다. 또한 이들 변수에 대한 분산분석 결과 7개 변수 모두 전반적으로 대부분의 주제분야 간에 있어서 평균값의 차이가 있는 것으로 나타났다.

• Wind and Structures
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• 제8권3호
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• pp.213-233
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• 2005

Wind uplift rating of roofing systems is based on standardized test methods. Roof specimens are placed in an apparatus with a specified table size (length and width) then subjected to the required wind load cycle. Currently, there is no consensus on the table size to be used by these testing protocols in spite of the fact that the table size plays a significant role in wind uplift performance. Part I of this paper presented a study with the objective to investigate the impact of table size on the performance of roofing systems. To achieve this purpose, extensive numerical experiments using the finite element method have been conducted and benchmarked with results obtained from the experimental work. The present contribution is a continuation of the previous research and can be divided into two parts: (1) Undertake additional numerical simulations for wider membranes that were not addressed in the previous works. Due to the advancement in membrane technology, wider membranes are now available in the market and are used in commercial roofing practice as it reduces installation cost and (2) Formulate a logical step to combine and generalize over 400 numerical tests and experiments on various roofing configurations and develop correction factors such that it can be of practical use to determine the wind uplift resistance of roofs.